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The map label for this gene is cobL [H]

Identifier: 159185387

GI number: 159185387

Start: 2799463

End: 2800722

Strand: Reverse

Name: cobL [H]

Synonym: Atu2798

Alternate gene names: 159185387

Gene position: 2800722-2799463 (Counterclockwise)

Preceding gene: 15890047

Following gene: 15890044

Centisome position: 98.56

GC content: 61.75

Gene sequence:

>1260_bases
ATGACATCTGAATATTCCGGAACGGCAAAGGCTTCCACTGAAAAGAACGAAAAGCCGTGGCTGTCCATTGTCGGTATAGG
CGAGGACGGGCTTCAGGGGCTGGGTGAAAATGCGCGTCAGGCGATAGAGGCAGCCGAGGTGGTTTTCGGCGGCAAACGCC
ATCTGGAACTGGCGGCTGGGGCCATTCGCGGCGAAGCGCGGGCCTGGCCGGTGCCGTTTGATGTGGACATGAACGATGTT
CTCGCATTGCGCGGCCGCCTGGTGTGTGTGCTGGCATCGGGCGATCCGTTCTTCTATGGTGCGGGGGTCACGCTTCTGCG
GCGGATTCCGGCGGAGGAAACGGCTTGTTATCCCTCGCCTTCCGCCTTTTCGCTGGCCGCCTCGCGGCTTGGCTGGGCCC
TGCAATCGGCCGAATGCGTTTCGCTGCATGGGCGCTCAATCGATCTGTTGCGGCCACATCTGCATCATGGCGCGCGGATC
ATCGCGCTGACGTCTGATGAGCGCGACCCAGCCTTGATTGCGCGGCTGCTGTCCGATGCCGGCTTCGGCCGTTCGGAATT
CATCCTGCTTGAAGCATTGGGCGGAGACCGGGAAAAGCGACGGCAAATCCGGGCTGCTGATTTTGGCTTTGAAGATACTG
ATCCGCTCAATGTCGTCGCGATCGAGGTCGTGGCGGATGAGGGTGCGCGCCTCCTGCCTTTTGCTCACGGGCTTGATGAC
GGCCTGTTTGAACATGACGGGCAGATCACCAAGCGCGAAATCCGCGCGGTGACGCTTTCGTCACTCGCCTCCCGTCGGGG
AGAACTGCTGTGGGATATTGGTGCGGGCTCCGGCTCGATCGGCATCGAATGGATGTTGTCGCATCCTTCGCTGCGCGCCA
TCGCCATCGAGCAGCATCCGGAAAGGGCTGAGCGGATTGCCCGCAATGCTGACGCTTTTGGTGTTCCGGGGCTTGAGGTC
ATGATCGGCACGGCTCCGGCGGCTTTTGAAGGCTTGTCTTCACCGGATGCGATCTTTATTGGCGGCGGCGGCAGTGAGAC
GGGTGTGCTGGAGGCCGCCATGGATGCTCTGAAACCGGGCGGGCGGCTGGTGGCCAATGCGGTGACGCTGGAAATGGAAG
CGGTATTGCTTGCTGCCCATGCGAAATTCGGCGGGTCGATGATCCGGCTGGAGGTCTCGCGGGCTGCTGCTGTCGGTTCC
ATGTCCGGCTGGCGTCCGGCTATGCCGGTGACACAATGGAGCTGGGTCAAGCCATGGTGA

Upstream 100 bases:

>100_bases
GGCCATGGACAGCAGAATTCGGTAGCCGGAGTCTTCCGCCAGCCGGCCGGCCAGAATGCGGGCATCCGCCGTGCCGCCAA
GGATGAGTATGGAGCGTGTC

Downstream 100 bases:

>100_bases
CCGTGGCTGGCATAGGCTGCCGCAAAGGTGCCGCCTCGGACGCGATCATTGCGGCTGTGCGGGCGGCGGAGCGTGCTTTT
GGCGTCACGGTTGACTATCT

Product: precorrin-6y methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTSEYSGTAKASTEKNEKPWLSIVGIGEDGLQGLGENARQAIEAAEVVFGGKRHLELAAGAIRGEARAWPVPFDVDMNDV
LALRGRLVCVLASGDPFFYGAGVTLLRRIPAEETACYPSPSAFSLAASRLGWALQSAECVSLHGRSIDLLRPHLHHGARI
IALTSDERDPALIARLLSDAGFGRSEFILLEALGGDREKRRQIRAADFGFEDTDPLNVVAIEVVADEGARLLPFAHGLDD
GLFEHDGQITKREIRAVTLSSLASRRGELLWDIGAGSGSIGIEWMLSHPSLRAIAIEQHPERAERIARNADAFGVPGLEV
MIGTAPAAFEGLSSPDAIFIGGGGSETGVLEAAMDALKPGGRLVANAVTLEMEAVLLAAHAKFGGSMIRLEVSRAAAVGS
MSGWRPAMPVTQWSWVKPW

Sequences:

>Translated_419_residues
MTSEYSGTAKASTEKNEKPWLSIVGIGEDGLQGLGENARQAIEAAEVVFGGKRHLELAAGAIRGEARAWPVPFDVDMNDV
LALRGRLVCVLASGDPFFYGAGVTLLRRIPAEETACYPSPSAFSLAASRLGWALQSAECVSLHGRSIDLLRPHLHHGARI
IALTSDERDPALIARLLSDAGFGRSEFILLEALGGDREKRRQIRAADFGFEDTDPLNVVAIEVVADEGARLLPFAHGLDD
GLFEHDGQITKREIRAVTLSSLASRRGELLWDIGAGSGSIGIEWMLSHPSLRAIAIEQHPERAERIARNADAFGVPGLEV
MIGTAPAAFEGLSSPDAIFIGGGGSETGVLEAAMDALKPGGRLVANAVTLEMEAVLLAAHAKFGGSMIRLEVSRAAAVGS
MSGWRPAMPVTQWSWVKPW
>Mature_418_residues
TSEYSGTAKASTEKNEKPWLSIVGIGEDGLQGLGENARQAIEAAEVVFGGKRHLELAAGAIRGEARAWPVPFDVDMNDVL
ALRGRLVCVLASGDPFFYGAGVTLLRRIPAEETACYPSPSAFSLAASRLGWALQSAECVSLHGRSIDLLRPHLHHGARII
ALTSDERDPALIARLLSDAGFGRSEFILLEALGGDREKRRQIRAADFGFEDTDPLNVVAIEVVADEGARLLPFAHGLDDG
LFEHDGQITKREIRAVTLSSLASRRGELLWDIGAGSGSIGIEWMLSHPSLRAIAIEQHPERAERIARNADAFGVPGLEVM
IGTAPAAFEGLSSPDAIFIGGGGSETGVLEAAMDALKPGGRLVANAVTLEMEAVLLAAHAKFGGSMIRLEVSRAAAVGSM
SGWRPAMPVTQWSWVKPW

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 44637; Mature: 44506

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEYSGTAKASTEKNEKPWLSIVGIGEDGLQGLGENARQAIEAAEVVFGGKRHLELAAG
CCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHHH
AIRGEARAWPVPFDVDMNDVLALRGRLVCVLASGDPFFYGAGVTLLRRIPAEETACYPSP
HHCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCEEEECHHHHHHHCCCCCCCCCCCC
SAFSLAASRLGWALQSAECVSLHGRSIDLLRPHLHHGARIIALTSDERDPALIARLLSDA
CHHHHHHHHHHHHHCCCCEEEECCCEEEEECHHHHCCCEEEEEECCCCCHHHHHHHHHHC
GFGRSEFILLEALGGDREKRRQIRAADFGFEDTDPLNVVAIEVVADEGARLLPFAHGLDD
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCC
GLFEHDGQITKREIRAVTLSSLASRRGELLWDIGAGSGSIGIEWMLSHPSLRAIAIEQHP
CHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCEEEEEECCCH
ERAERIARNADAFGVPGLEVMIGTAPAAFEGLSSPDAIFIGGGGSETGVLEAAMDALKPG
HHHHHHHHCCCCCCCCCEEEEEECCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCC
GRLVANAVTLEMEAVLLAAHAKFGGSMIRLEVSRAAAVGSMSGWRPAMPVTQWSWVKPW
CEEEEEEEEEEHHHHEEEHHHHCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSEYSGTAKASTEKNEKPWLSIVGIGEDGLQGLGENARQAIEAAEVVFGGKRHLELAAG
CCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHHH
AIRGEARAWPVPFDVDMNDVLALRGRLVCVLASGDPFFYGAGVTLLRRIPAEETACYPSP
HHCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCEEEECHHHHHHHCCCCCCCCCCCC
SAFSLAASRLGWALQSAECVSLHGRSIDLLRPHLHHGARIIALTSDERDPALIARLLSDA
CHHHHHHHHHHHHHCCCCEEEECCCEEEEECHHHHCCCEEEEEECCCCCHHHHHHHHHHC
GFGRSEFILLEALGGDREKRRQIRAADFGFEDTDPLNVVAIEVVADEGARLLPFAHGLDD
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCC
GLFEHDGQITKREIRAVTLSSLASRRGELLWDIGAGSGSIGIEWMLSHPSLRAIAIEQHP
CHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCEEEEEECCCH
ERAERIARNADAFGVPGLEVMIGTAPAAFEGLSSPDAIFIGGGGSETGVLEAAMDALKPG
HHHHHHHHCCCCCCCCCEEEEEECCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCC
GRLVANAVTLEMEAVLLAAHAKFGGSMIRLEVSRAAAVGSMSGWRPAMPVTQWSWVKPW
CEEEEEEEEEEHHHHEEEHHHHCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]