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The map label for this gene is tbpA [H]

Identifier: 159185343

GI number: 159185343

Start: 2699179

End: 2700192

Strand: Reverse

Name: tbpA [H]

Synonym: Atu2714

Alternate gene names: 159185343

Gene position: 2700192-2699179 (Counterclockwise)

Preceding gene: 15889967

Following gene: 15889965

Centisome position: 95.02

GC content: 57.79

Gene sequence:

>1014_bases
GTGCGCCGTCGTCTTTTCCTGAATTCCGTCATTGCCGCCTCGCTGTTTCTGCCCGGTTTAGCCGCGGCGCAGGACAAGCC
GGAACTGACCGTCTACACCTATGAAAGCTTCGTTTCCGAATGGGGCCCCGGCCCCAAGGTGAAGGAAGCCTTCGAGAAGG
TTTGCGTCTGCACGGTCAATTTTGTCGGTGTCGCGGATGGCGTGGCGCTGCTCAATCGTCTGAAACTTGAGGGCAGCGGT
TCCAAGGCGGACGTCGTGGTCGGGCTCGACACCAATCTTGTCGCGGAAGCCAAACAGACCGGCCTTTTTGACGCCAGTGG
CATCGATGCATCGGCGGCCAAGGTGCCGGGCGGTTACAAGGACGATGTTTTCGTACCCTATGATTATGGGCATTTCGCTG
TGATCTATGACACGCAGGCGGTGAAAAACCCGCCGGCGAGCCTTAAAGAACTGGTGGAAGGCGACTCCGCGCAGAAGATC
GCCATTCAGGACCCGCGTACCTCCACACCTGGGCTTGGCCTGCTTTTGTGGGTAAAGTCAGTTTATGGCGACAAGGCGCC
GGAGGCTTGGGCAAAGCTCAGGAAGCGCATTCTCACCGTCACGCCCGGCTGGTCGGAATCCTATGGCCTGTTCACCAAGG
GAGAGGTGCCGATGGTGCTCTCCTACACCACCTCGCCGGCCTATCACATGGTCGCCGAAAAGTCGGACCGTTATCAGGCT
GCGGCCTTTTCGGAAGGGCATTACATCCAGATCGAAGTGTCCGGCCTTCTCAAAAACGCACCGCACAAGGAGCTGGCAAA
GCAGTTTCTCGCTTTCACACTGACATCAGGTTTTCAGGATGCCATTCCCGAAAACAACTGGATGATGCCGGTTGCGGCAA
CGTCGGCGCCCTTGCCCGAGGCATTTTCCAAACTCGTCGTGCCGCAGAAGACCTTTCTGATGGATCCCGAAGAGGTGGCG
AAGAACCGCAAAGCCTGGATCGACGAATGGCTTTCGGCCATGAGCATGAACTGA

Upstream 100 bases:

>100_bases
GCTTGCCAACCCGAAGAACCTGATCCGGTTCATACCGGCGGAGGGATTAGACGGCTTAAAGGCAAGCGGCTACTCCTTCT
CGTCTTTTGAGGAGATACCC

Downstream 100 bases:

>100_bases
GGAAGAGGCACGCCCGCGCATGATGCTGCGTCGCGATTATCGGCGGTCGATCATTTTGGGGACGGCGGCTTTTGCCGCCG
TTTTCCTGTTCATGGCGCTC

Product: thiamine transporter substrate binding subunit

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRRRLFLNSVIAASLFLPGLAAAQDKPELTVYTYESFVSEWGPGPKVKEAFEKVCVCTVNFVGVADGVALLNRLKLEGSG
SKADVVVGLDTNLVAEAKQTGLFDASGIDASAAKVPGGYKDDVFVPYDYGHFAVIYDTQAVKNPPASLKELVEGDSAQKI
AIQDPRTSTPGLGLLLWVKSVYGDKAPEAWAKLRKRILTVTPGWSESYGLFTKGEVPMVLSYTTSPAYHMVAEKSDRYQA
AAFSEGHYIQIEVSGLLKNAPHKELAKQFLAFTLTSGFQDAIPENNWMMPVAATSAPLPEAFSKLVVPQKTFLMDPEEVA
KNRKAWIDEWLSAMSMN

Sequences:

>Translated_337_residues
MRRRLFLNSVIAASLFLPGLAAAQDKPELTVYTYESFVSEWGPGPKVKEAFEKVCVCTVNFVGVADGVALLNRLKLEGSG
SKADVVVGLDTNLVAEAKQTGLFDASGIDASAAKVPGGYKDDVFVPYDYGHFAVIYDTQAVKNPPASLKELVEGDSAQKI
AIQDPRTSTPGLGLLLWVKSVYGDKAPEAWAKLRKRILTVTPGWSESYGLFTKGEVPMVLSYTTSPAYHMVAEKSDRYQA
AAFSEGHYIQIEVSGLLKNAPHKELAKQFLAFTLTSGFQDAIPENNWMMPVAATSAPLPEAFSKLVVPQKTFLMDPEEVA
KNRKAWIDEWLSAMSMN
>Mature_337_residues
MRRRLFLNSVIAASLFLPGLAAAQDKPELTVYTYESFVSEWGPGPKVKEAFEKVCVCTVNFVGVADGVALLNRLKLEGSG
SKADVVVGLDTNLVAEAKQTGLFDASGIDASAAKVPGGYKDDVFVPYDYGHFAVIYDTQAVKNPPASLKELVEGDSAQKI
AIQDPRTSTPGLGLLLWVKSVYGDKAPEAWAKLRKRILTVTPGWSESYGLFTKGEVPMVLSYTTSPAYHMVAEKSDRYQA
AAFSEGHYIQIEVSGLLKNAPHKELAKQFLAFTLTSGFQDAIPENNWMMPVAATSAPLPEAFSKLVVPQKTFLMDPEEVA
KNRKAWIDEWLSAMSMN

Specific function: Part of the ABC transporter complex thiBPQ involved in thiamine import [H]

COG id: COG4143

COG function: function code H; ABC-type thiamine transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1786255, Length=310, Percent_Identity=58.7096774193548, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR005948
- InterPro:   IPR005967 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 36750; Mature: 36750

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRLFLNSVIAASLFLPGLAAAQDKPELTVYTYESFVSEWGPGPKVKEAFEKVCVCTVN
CCCHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHEEE
FVGVADGVALLNRLKLEGSGSKADVVVGLDTNLVAEAKQTGLFDASGIDASAAKVPGGYK
HHHHHHHHHHHHHHEECCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHCCCCCCC
DDVFVPYDYGHFAVIYDTQAVKNPPASLKELVEGDSAQKIAIQDPRTSTPGLGLLLWVKS
CCEEEEECCCCEEEEEECHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHH
VYGDKAPEAWAKLRKRILTVTPGWSESYGLFTKGEVPMVLSYTTSPAYHMVAEKSDRYQA
HHCCCCHHHHHHHHHHEEEECCCCCCCCCEEECCCCCEEEEECCCCCEEEHHCCCCCEEE
AAFSEGHYIQIEVSGLLKNAPHKELAKQFLAFTLTSGFQDAIPENNWMMPVAATSAPLPE
EEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCHH
AFSKLVVPQKTFLMDPEEVAKNRKAWIDEWLSAMSMN
HHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRRLFLNSVIAASLFLPGLAAAQDKPELTVYTYESFVSEWGPGPKVKEAFEKVCVCTVN
CCCHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHEEE
FVGVADGVALLNRLKLEGSGSKADVVVGLDTNLVAEAKQTGLFDASGIDASAAKVPGGYK
HHHHHHHHHHHHHHEECCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHCCCCCCC
DDVFVPYDYGHFAVIYDTQAVKNPPASLKELVEGDSAQKIAIQDPRTSTPGLGLLLWVKS
CCEEEEECCCCEEEEEECHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHH
VYGDKAPEAWAKLRKRILTVTPGWSESYGLFTKGEVPMVLSYTTSPAYHMVAEKSDRYQA
HHCCCCHHHHHHHHHHEEEECCCCCCCCCEEECCCCCEEEEECCCCCEEEHHCCCCCEEE
AAFSEGHYIQIEVSGLLKNAPHKELAKQFLAFTLTSGFQDAIPENNWMMPVAATSAPLPE
EEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCHH
AFSKLVVPQKTFLMDPEEVAKNRKAWIDEWLSAMSMN
HHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA