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The map label for this gene is ffh [H]

Identifier: 159185333

GI number: 159185333

Start: 2682032

End: 2683603

Strand: Direct

Name: ffh [H]

Synonym: Atu2697

Alternate gene names: 159185333

Gene position: 2682032-2683603 (Clockwise)

Preceding gene: 159185328

Following gene: 15889952

Centisome position: 94.39

GC content: 61.64

Gene sequence:

>1572_bases
ATGTTTGAAAACCTCCAGGACCGCCTTGGTTCCATTCTGAATGGACTGACCGGCCGTGGCGCGCTGACGGAAGCCGATGT
TGCCGCCGCCCTGCGCGAGGTTCGCCGTGCGCTTCTGGAAGCGGACGTGGCGCTGGAAGTCGTGCGTTCCTTCACCGACA
GGGTGCGTGAAAAGGCCGTCGGCGCAGCGGTTCTGAAATCCATCAAGCCCGGCCAGATGGTCGTCAAGATCGTGCATGAC
GAGCTTGTCGAAATGCTTGGCACCGAAGGCGTTTCTATCGACCTGCATGCGGCCGCCCCCGTCGTCATCATGATGGTGGG
TCTGCAGGGCTCGGGTAAAACCACCACAACTGGCAAGATCGCCAAGCGCCTGACCGACCGCGACAAGAAGAAGGTGCTGA
TGGCATCTCTCGACACGCGTCGTCCGGCCGCACAGGAACAGCTGCGCCAGCTCGGCGTCCAGACGGGCGTCGATACGCTG
CCGATCATCGCCGGCCAGTCGCCGACAGATATCGCCGCACGCGCCGTACAGGCTGCGAAACTCGGCGGCCACGACGTCGT
CATTCTCGATACTGCCGGCCGCACGCACATCGACGAACCCTTGATGCTGGAAATGGCCGACATCAAGAAGAAATCCAACC
CGCATGAAATCCTGCTGGTAGCGGATTCGCTGACCGGTCAGGACGCCGTCAACCTCGCGCGCAATTTCGATGAGCGTGTC
GGCATCACCGGCCTTGTGCTTACCCGTATGGACGGCGACGGACGCGGCGGTGCGGCCCTTTCCATGCGCGCCGTCACCGG
CAAGCCGATTAAGCTGATCGGTATCGGCGAGCGCATGAACGAACTCGACGAGTTCCATCCGCGCCGTATCGCCGACCGTA
TTCTCGGCATGGGCGACATCGTCTCGCTGGTCGAAAAGGCCGCCGAAAACATCGATGCGGAAAAAGCCCGCTCCATGGCC
GAGAAGATGGCCAAGGGCAAGTTCGACCTCAACGATCTGGCCGACCAGCTTGGTCAGATGAAGAAGATGGGCGGCATGGG
CGGCATCATGGGACTGATGCCCGGCATGGCCGGCATGAAGGACAAGATGGCTTCGGCCGGTATGAACGACAAGATGTTCG
ACCGCCAGATCGCCATCATCTCTTCTATGACCAAGGCCGAGCGCGCCAATCCGGATATTCTGAAACACAGCCGCAAGAAG
CGCATCGCCGCCGGCTCCGGCACCGATGCCGCCGAAATCAACAAGCTCTTGAAAATGCATCGCGGCATGGCCGACATGAT
GAAGGCCATGGGCGGCAAGGGCAAAGGCGGCATCATGAAACAGATGATGGGCGGCCTTGCCGGCAAGATGGGTCTTGGTG
GGATGATGGGCGGCGGCATGCCTGATCTGTCGAACATCGATCCGAAGCAGCTTGAGGCGCTCCAGAAACAGGCTGAAGCC
GCCGGTCTCGGCAAGCCGGGTGCAATGCCCGGCATGGGTGGTCTGCCGGGCGGATTGCCCGGTCTCGGTGGGGCAAAGCT
GCCGGGTCTTGGTGGCATGCCGGGCCTGCCTGGTTTCCCGAAAAAGAAGTGA

Upstream 100 bases:

>100_bases
CAGCGCGATGCGCCCTCGGGTGCTTTTTGGCTTTGCGTCTTGTTTTTGCCAGCGAAAGCACCGACGTTTCGGAAACCCCG
GAACGAAGAAGGAAGAAACG

Downstream 100 bases:

>100_bases
GGGCGACGCCAATGAACAATACAGAGGTGAAAGCCCAGCTTTCCGAATACCGCCAGTCGATCGACAATATCGATGCCGCA
CTGGTTCACATTCTTGCTGA

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MFENLQDRLGSILNGLTGRGALTEADVAAALREVRRALLEADVALEVVRSFTDRVREKAVGAAVLKSIKPGQMVVKIVHD
ELVEMLGTEGVSIDLHAAAPVVIMMVGLQGSGKTTTTGKIAKRLTDRDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTL
PIIAGQSPTDIAARAVQAAKLGGHDVVILDTAGRTHIDEPLMLEMADIKKKSNPHEILLVADSLTGQDAVNLARNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGIGERMNELDEFHPRRIADRILGMGDIVSLVEKAAENIDAEKARSMA
EKMAKGKFDLNDLADQLGQMKKMGGMGGIMGLMPGMAGMKDKMASAGMNDKMFDRQIAIISSMTKAERANPDILKHSRKK
RIAAGSGTDAAEINKLLKMHRGMADMMKAMGGKGKGGIMKQMMGGLAGKMGLGGMMGGGMPDLSNIDPKQLEALQKQAEA
AGLGKPGAMPGMGGLPGGLPGLGGAKLPGLGGMPGLPGFPKKK

Sequences:

>Translated_523_residues
MFENLQDRLGSILNGLTGRGALTEADVAAALREVRRALLEADVALEVVRSFTDRVREKAVGAAVLKSIKPGQMVVKIVHD
ELVEMLGTEGVSIDLHAAAPVVIMMVGLQGSGKTTTTGKIAKRLTDRDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTL
PIIAGQSPTDIAARAVQAAKLGGHDVVILDTAGRTHIDEPLMLEMADIKKKSNPHEILLVADSLTGQDAVNLARNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGIGERMNELDEFHPRRIADRILGMGDIVSLVEKAAENIDAEKARSMA
EKMAKGKFDLNDLADQLGQMKKMGGMGGIMGLMPGMAGMKDKMASAGMNDKMFDRQIAIISSMTKAERANPDILKHSRKK
RIAAGSGTDAAEINKLLKMHRGMADMMKAMGGKGKGGIMKQMMGGLAGKMGLGGMMGGGMPDLSNIDPKQLEALQKQAEA
AGLGKPGAMPGMGGLPGGLPGLGGAKLPGLGGMPGLPGFPKKK
>Mature_523_residues
MFENLQDRLGSILNGLTGRGALTEADVAAALREVRRALLEADVALEVVRSFTDRVREKAVGAAVLKSIKPGQMVVKIVHD
ELVEMLGTEGVSIDLHAAAPVVIMMVGLQGSGKTTTTGKIAKRLTDRDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTL
PIIAGQSPTDIAARAVQAAKLGGHDVVILDTAGRTHIDEPLMLEMADIKKKSNPHEILLVADSLTGQDAVNLARNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGIGERMNELDEFHPRRIADRILGMGDIVSLVEKAAENIDAEKARSMA
EKMAKGKFDLNDLADQLGQMKKMGGMGGIMGLMPGMAGMKDKMASAGMNDKMFDRQIAIISSMTKAERANPDILKHSRKK
RIAAGSGTDAAEINKLLKMHRGMADMMKAMGGKGKGGIMKQMMGGLAGKMGLGGMMGGGMPDLSNIDPKQLEALQKQAEA
AGLGKPGAMPGMGGLPGGLPGLGGAKLPGLGGMPGLPGFPKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=529, Percent_Identity=30.0567107750473, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI226371618, Length=461, Percent_Identity=29.9349240780911, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI295424842, Length=312, Percent_Identity=29.1666666666667, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI23308697, Length=312, Percent_Identity=29.1666666666667, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=32.0754716981132, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=53.3018867924528, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1789874, Length=254, Percent_Identity=37.4015748031496, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=489, Percent_Identity=27.4028629856851, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=31.8791946308725, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=537, Percent_Identity=30.5400372439479, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320498, Length=318, Percent_Identity=27.0440251572327, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17647949, Length=502, Percent_Identity=29.4820717131474, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24641198, Length=306, Percent_Identity=30.0653594771242, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 54992; Mature: 54992

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.6 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENLQDRLGSILNGLTGRGALTEADVAAALREVRRALLEADVALEVVRSFTDRVREKAV
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAVLKSIKPGQMVVKIVHDELVEMLGTEGVSIDLHAAAPVVIMMVGLQGSGKTTTTGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCHHHEECCCCCCCCCHHHHH
AKRLTDRDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTLPIIAGQSPTDIAARAVQAAK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMLEMADIKKKSNPHEILLVADSLTGQDAVNLARNFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGIGERMNELDEFHPRRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHH
VSLVEKAAENIDAEKARSMAEKMAKGKFDLNDLADQLGQMKKMGGMGGIMGLMPGMAGMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHH
DKMASAGMNDKMFDRQIAIISSMTKAERANPDILKHSRKKRIAAGSGTDAAEINKLLKMH
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RGMADMMKAMGGKGKGGIMKQMMGGLAGKMGLGGMMGGGMPDLSNIDPKQLEALQKQAEA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AGLGKPGAMPGMGGLPGGLPGLGGAKLPGLGGMPGLPGFPKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFENLQDRLGSILNGLTGRGALTEADVAAALREVRRALLEADVALEVVRSFTDRVREKAV
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAVLKSIKPGQMVVKIVHDELVEMLGTEGVSIDLHAAAPVVIMMVGLQGSGKTTTTGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCHHHEECCCCCCCCCHHHHH
AKRLTDRDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTLPIIAGQSPTDIAARAVQAAK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMLEMADIKKKSNPHEILLVADSLTGQDAVNLARNFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGIGERMNELDEFHPRRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHH
VSLVEKAAENIDAEKARSMAEKMAKGKFDLNDLADQLGQMKKMGGMGGIMGLMPGMAGMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHH
DKMASAGMNDKMFDRQIAIISSMTKAERANPDILKHSRKKRIAAGSGTDAAEINKLLKMH
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RGMADMMKAMGGKGKGGIMKQMMGGLAGKMGLGGMMGGGMPDLSNIDPKQLEALQKQAEA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AGLGKPGAMPGMGGLPGGLPGLGGAKLPGLGGMPGLPGFPKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA