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The map label for this gene is dcp [H]

Identifier: 159185314

GI number: 159185314

Start: 2647213

End: 2649273

Strand: Reverse

Name: dcp [H]

Synonym: Atu2664

Alternate gene names: 159185314

Gene position: 2649273-2647213 (Counterclockwise)

Preceding gene: 159185316

Following gene: 15889919

Centisome position: 93.23

GC content: 57.3

Gene sequence:

>2061_bases
ATGCCATTGAAGACCGCCCTTTATCCCGCGCTGGTTGACTGGAACGGCCATAATGGCCTGCCGAAATTCGATGCGGTCAA
GGATGAGGATTTTGCGCCCGCTTTCGATGCCGCGCTTTTTTCCCATGAGCAGGAAATCGATGCGATTGCGGGAAATCCAG
AGGCGCCGAGTTTCGAAAACACGGTGACCGCACTCGAAATTGCAGGTGACGAGCTCTCGCGTATCTCGTCGCTGTTCTGG
AACAAAGCCGGCGCCAACACCAATGGTGTGATCCAGGCGCTCGAGCGGGAAATCGCGCCAAAGATGTCGCGACATTATTC
GAAGATCGGCATGAACGAAGCGCTGTTCAAGCGCATCGACACGCTGTGGGAAAAGCGCGAGGCGCTTGGGCTGACAGGCG
AAGAAAAACGGGTTCTCGAACGCCATTGGAAAGGTTTTGTCCACTCAGGTGCGAAATTGCCGAAAGAGCGGCAGGAGCGG
CTGGCGGCCATCAATGAAGAGCTTGCCGGTCTCGGCGCGAAATTCGGCCAGAACGTGCTGGCGGATGAGAAGAGCTGGAA
GCTTTTGCTTTCCACGGATGAAGAGCTTGCGGGCATCCCCGGCTTCCTGCGCGACGCTATGGCGGGGGCAGCCGGCGAGC
ACGGGGAGGACGGCAAATTTGCCGTTACCCTTTCCCGCTCGATCATCGAGCCCTTCCTGACTTTTTCAGAACGGCGCGAC
CTGCGCGAACAGGCCTTCAAGGCCTGGGTGGCGCGGGGCGAGAACGGTGGCGAGACCGACAATCGCGAGATCGTCCGCCG
CACCCTCGAACTGCGCGAGGAAAAGGCAAAACTTCTTGGTTATGCGAATTTCGCTGCCTATAAGCTGGATGATACGATGG
CGAAGACGCCGGATGCGGTGAACGGTCTTCTCCGTCAGGTCTGGGAAAAAGCCGTTCAACGGGCCGGTGAGGAAGAGGCT
GGACTTGCCGCCATCATCGCCGAGGAAGGCAAGAACCACGAGGTGCTGCCGTGGGACTGGCGGCATTATGCCGAAAAGCT
CCGGGCACAGAAATTCAATTTCTCCGAGGCGGAATTGAAGCCCTATCTGCAGCTGGAAAAGATCATCGAAGCCTGTTTCG
ATGTGGCAGAGCGGCTGTTTGGAATTCATGCGGTCGAAGTGAAGGGCGTTGTGGGCTATCACCCGGATGTGCGAATTTTC
GAAATCCGCGATAACAAGGGCGATCTGAAGGCCATGTTCCTCGGCGACTATTTCGCCCGCCCCTCCAAACGATCAGGCGC
CTGGATGAGCTCCTTCCAGTCGCAGCACAAGCTGCCGCTGAAGGACGGCACGGTCGGTGAAATCCCGATCATCTACAATG
TCTGCAATTTCGCGAAACCAGCCGAAGGAAAACCGGCGCTGCTTTCGCTCGACGATGCGCGCACGCTGTTCCATGAATTC
GGCCACGCCTTGCATGGCATGTTGTCCGATGTCACCTATCCCTCGGTATCCGGAACGGGTGTCTCGCGCGATTTCGTCGA
ATTGCCGTCCCAGCTTTACGAACATTGGCTGACGGTGCCGGAAATTCTCGAAAAATACGCGCTGCACTATGAGACTGGTG
CGCCGATGCCGAAGGCGCTGCTGGACAAGGTTCTGGCCGCGCAGACCTTCAATGCCGGTTTCAACACGGTGGAATTCACC
TCTTCGGCGATCGTCGATATGGCGTTTCACACCCGTGACAGCGTTGCCGATCCGATGGCGGTTCAGGGTGAGGTACTTTC
TGGCCTCAATATGCCAAAATCCATCGTCATGCGGCACGCGACGCCGCATTTCCAGCATGTGTTTTCGGGCGACGGTTATT
CCGCCGGTTATTATTCCTACATGTGGTCGGAAGTTCTCGATGCCGATGCCTTTGCCGCCTTTGAGGAAACCGGCAACGCT
TTTGATGGCGAGATGGCGCGCAGGCTGAAGGATAATATCTATTCCGTCGGGGGCTCGATCGATCCTGAAGAGGCTTATCT
CGCGTTCCGCGGCAAGATGCCGAGCCCGGATGCGATGCTTTTGAAGCGCGGTCTCGTATAA

Upstream 100 bases:

>100_bases
GAGAAAGCGTCGGCATTTTTCGACCTCCGCTTAGCATATTGAATTGACGCTAGAGGCATGCCCATATGGATTTTAATCGG
AATCGCACAAGGAAGATGAA

Downstream 100 bases:

>100_bases
GAGACTGTCATAATTCTCAGCTAGAACCTGAGCGCAGGGGGCTTATGACATGAGCCCCCCTTTCGCATTTGCAAAAAAAA
GGTTATGAGCGCGCCAAACT

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MPLKTALYPALVDWNGHNGLPKFDAVKDEDFAPAFDAALFSHEQEIDAIAGNPEAPSFENTVTALEIAGDELSRISSLFW
NKAGANTNGVIQALEREIAPKMSRHYSKIGMNEALFKRIDTLWEKREALGLTGEEKRVLERHWKGFVHSGAKLPKERQER
LAAINEELAGLGAKFGQNVLADEKSWKLLLSTDEELAGIPGFLRDAMAGAAGEHGEDGKFAVTLSRSIIEPFLTFSERRD
LREQAFKAWVARGENGGETDNREIVRRTLELREEKAKLLGYANFAAYKLDDTMAKTPDAVNGLLRQVWEKAVQRAGEEEA
GLAAIIAEEGKNHEVLPWDWRHYAEKLRAQKFNFSEAELKPYLQLEKIIEACFDVAERLFGIHAVEVKGVVGYHPDVRIF
EIRDNKGDLKAMFLGDYFARPSKRSGAWMSSFQSQHKLPLKDGTVGEIPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
GHALHGMLSDVTYPSVSGTGVSRDFVELPSQLYEHWLTVPEILEKYALHYETGAPMPKALLDKVLAAQTFNAGFNTVEFT
SSAIVDMAFHTRDSVADPMAVQGEVLSGLNMPKSIVMRHATPHFQHVFSGDGYSAGYYSYMWSEVLDADAFAAFEETGNA
FDGEMARRLKDNIYSVGGSIDPEEAYLAFRGKMPSPDAMLLKRGLV

Sequences:

>Translated_686_residues
MPLKTALYPALVDWNGHNGLPKFDAVKDEDFAPAFDAALFSHEQEIDAIAGNPEAPSFENTVTALEIAGDELSRISSLFW
NKAGANTNGVIQALEREIAPKMSRHYSKIGMNEALFKRIDTLWEKREALGLTGEEKRVLERHWKGFVHSGAKLPKERQER
LAAINEELAGLGAKFGQNVLADEKSWKLLLSTDEELAGIPGFLRDAMAGAAGEHGEDGKFAVTLSRSIIEPFLTFSERRD
LREQAFKAWVARGENGGETDNREIVRRTLELREEKAKLLGYANFAAYKLDDTMAKTPDAVNGLLRQVWEKAVQRAGEEEA
GLAAIIAEEGKNHEVLPWDWRHYAEKLRAQKFNFSEAELKPYLQLEKIIEACFDVAERLFGIHAVEVKGVVGYHPDVRIF
EIRDNKGDLKAMFLGDYFARPSKRSGAWMSSFQSQHKLPLKDGTVGEIPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
GHALHGMLSDVTYPSVSGTGVSRDFVELPSQLYEHWLTVPEILEKYALHYETGAPMPKALLDKVLAAQTFNAGFNTVEFT
SSAIVDMAFHTRDSVADPMAVQGEVLSGLNMPKSIVMRHATPHFQHVFSGDGYSAGYYSYMWSEVLDADAFAAFEETGNA
FDGEMARRLKDNIYSVGGSIDPEEAYLAFRGKMPSPDAMLLKRGLV
>Mature_685_residues
PLKTALYPALVDWNGHNGLPKFDAVKDEDFAPAFDAALFSHEQEIDAIAGNPEAPSFENTVTALEIAGDELSRISSLFWN
KAGANTNGVIQALEREIAPKMSRHYSKIGMNEALFKRIDTLWEKREALGLTGEEKRVLERHWKGFVHSGAKLPKERQERL
AAINEELAGLGAKFGQNVLADEKSWKLLLSTDEELAGIPGFLRDAMAGAAGEHGEDGKFAVTLSRSIIEPFLTFSERRDL
REQAFKAWVARGENGGETDNREIVRRTLELREEKAKLLGYANFAAYKLDDTMAKTPDAVNGLLRQVWEKAVQRAGEEEAG
LAAIIAEEGKNHEVLPWDWRHYAEKLRAQKFNFSEAELKPYLQLEKIIEACFDVAERLFGIHAVEVKGVVGYHPDVRIFE
IRDNKGDLKAMFLGDYFARPSKRSGAWMSSFQSQHKLPLKDGTVGEIPIIYNVCNFAKPAEGKPALLSLDDARTLFHEFG
HALHGMLSDVTYPSVSGTGVSRDFVELPSQLYEHWLTVPEILEKYALHYETGAPMPKALLDKVLAAQTFNAGFNTVEFTS
SAIVDMAFHTRDSVADPMAVQGEVLSGLNMPKSIVMRHATPHFQHVFSGDGYSAGYYSYMWSEVLDADAFAAFEETGNAF
DGEMARRLKDNIYSVGGSIDPEEAYLAFRGKMPSPDAMLLKRGLV

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=612, Percent_Identity=30.5555555555556, Blast_Score=247, Evalue=3e-65,
Organism=Homo sapiens, GI14149738, Length=652, Percent_Identity=26.3803680981595, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI156105687, Length=672, Percent_Identity=25.297619047619, Blast_Score=172, Evalue=9e-43,
Organism=Escherichia coli, GI1787819, Length=687, Percent_Identity=39.8835516739447, Blast_Score=474, Evalue=1e-134,
Organism=Escherichia coli, GI1789913, Length=679, Percent_Identity=35.1988217967599, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI32565901, Length=634, Percent_Identity=20.820189274448, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71999758, Length=584, Percent_Identity=20.0342465753425, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319793, Length=658, Percent_Identity=25.3799392097264, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322715, Length=363, Percent_Identity=26.7217630853994, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356111, Length=569, Percent_Identity=24.0773286467487, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI20129717, Length=588, Percent_Identity=22.6190476190476, Blast_Score=135, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 76344; Mature: 76213

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKTALYPALVDWNGHNGLPKFDAVKDEDFAPAFDAALFSHEQEIDAIAGNPEAPSFEN
CCCCHHHCHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVTALEIAGDELSRISSLFWNKAGANTNGVIQALEREIAPKMSRHYSKIGMNEALFKRID
CCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLWEKREALGLTGEEKRVLERHWKGFVHSGAKLPKERQERLAAINEELAGLGAKFGQNVL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
ADEKSWKLLLSTDEELAGIPGFLRDAMAGAAGEHGEDGKFAVTLSRSIIEPFLTFSERRD
CCCCCCEEEEECCHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHH
LREQAFKAWVARGENGGETDNREIVRRTLELREEKAKLLGYANFAAYKLDDTMAKTPDAV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHCCCHHH
NGLLRQVWEKAVQRAGEEEAGLAAIIAEEGKNHEVLPWDWRHYAEKLRAQKFNFSEAELK
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
PYLQLEKIIEACFDVAERLFGIHAVEVKGVVGYHPDVRIFEIRDNKGDLKAMFLGDYFAR
HHHHHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCEEEEEEECCCCCEEEEEHHHHHCC
PSKRSGAWMSSFQSQHKLPLKDGTVGEIPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHH
GHALHGMLSDVTYPSVSGTGVSRDFVELPSQLYEHWLTVPEILEKYALHYETGAPMPKAL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
LDKVLAAQTFNAGFNTVEFTSSAIVDMAFHTRDSVADPMAVQGEVLSGLNMPKSIVMRHA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHCC
TPHFQHVFSGDGYSAGYYSYMWSEVLDADAFAAFEETGNAFDGEMARRLKDNIYSVGGSI
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
DPEEAYLAFRGKMPSPDAMLLKRGLV
CHHHHHEEEECCCCCCHHHHHHCCCC
>Mature Secondary Structure 
PLKTALYPALVDWNGHNGLPKFDAVKDEDFAPAFDAALFSHEQEIDAIAGNPEAPSFEN
CCCHHHCHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVTALEIAGDELSRISSLFWNKAGANTNGVIQALEREIAPKMSRHYSKIGMNEALFKRID
CCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLWEKREALGLTGEEKRVLERHWKGFVHSGAKLPKERQERLAAINEELAGLGAKFGQNVL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
ADEKSWKLLLSTDEELAGIPGFLRDAMAGAAGEHGEDGKFAVTLSRSIIEPFLTFSERRD
CCCCCCEEEEECCHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHH
LREQAFKAWVARGENGGETDNREIVRRTLELREEKAKLLGYANFAAYKLDDTMAKTPDAV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHCCCHHH
NGLLRQVWEKAVQRAGEEEAGLAAIIAEEGKNHEVLPWDWRHYAEKLRAQKFNFSEAELK
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
PYLQLEKIIEACFDVAERLFGIHAVEVKGVVGYHPDVRIFEIRDNKGDLKAMFLGDYFAR
HHHHHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCEEEEEEECCCCCEEEEEHHHHHCC
PSKRSGAWMSSFQSQHKLPLKDGTVGEIPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHH
GHALHGMLSDVTYPSVSGTGVSRDFVELPSQLYEHWLTVPEILEKYALHYETGAPMPKAL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
LDKVLAAQTFNAGFNTVEFTSSAIVDMAFHTRDSVADPMAVQGEVLSGLNMPKSIVMRHA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHCC
TPHFQHVFSGDGYSAGYYSYMWSEVLDADAFAAFEETGNAFDGEMARRLKDNIYSVGGSI
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
DPEEAYLAFRGKMPSPDAMLLKRGLV
CHHHHHEEEECCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]