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The map label for this gene is ppa

Identifier: 159185313

GI number: 159185313

Start: 2643817

End: 2644350

Strand: Reverse

Name: ppa

Synonym: Atu2661

Alternate gene names: 159185313

Gene position: 2644350-2643817 (Counterclockwise)

Preceding gene: 15889918

Following gene: 159185311

Centisome position: 93.06

GC content: 57.49

Gene sequence:

>534_bases
ATGCGTATCGATGCAATTTCCATAGGCAAGAACCCGCCGGATGACATAAACGTTATCGTTGAAGTGCCGGTCGGTGGCCA
TCCGATCAAGTACGAGATGGACAAGGACGCGGGTGCGCTGATCGTCGATCGCTTCCTCTACACGCCGATGACCTATCCGG
GTAACTATGGCTTCGTGCCGCACACCCTGTCCGACGATGGCGACCCGATCGATGTTCTCATCTGCAACACCCGTCCGCTG
GTTCCCGGCTGCGTGATCAATGTCCGCCCCATCGGCGTGATGATCATGGAAGATGATGGCGGCAAGGACGAGAAAATCCT
CGCCGTGCCGGCTCCGAAGCTGACGCAGCGTTACGACAAGGTCCATAACTACACCGACCTGCCGGAAATCACGCTGAAGC
AGATCGAGCATTTCTTCGAGCACTACAAGGATCTGGAGCCCGGCAAGTGGGTGAAGATGGGCGGCTGGCAGGATGTCGAC
GTCGCCAAGAAGCTGATCGTCGAAGCCATCGAGCGTTACAAGACGCAGGGCTGA

Upstream 100 bases:

>100_bases
AAATCCGGCATTCTGTCTTATCCGCTCAAAGCCATGTTGCAATACGGCGACTTTCCCAGTATCGAAAACCAAATCCAACC
CGTCGAATTGAGGGAAGCGA

Downstream 100 bases:

>100_bases
TAGCCCTAGCCCGCCAGCTTTTTAAAGAGCTTTTCGAAATCCTCCGGGTCGGTATCGATCCGGAGGATTTTTTTGCGCGC
TGTTTCGCCTGAGATGAAGG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRIDAISIGKNPPDDINVIVEVPVGGHPIKYEMDKDAGALIVDRFLYTPMTYPGNYGFVPHTLSDDGDPIDVLICNTRPL
VPGCVINVRPIGVMIMEDDGGKDEKILAVPAPKLTQRYDKVHNYTDLPEITLKQIEHFFEHYKDLEPGKWVKMGGWQDVD
VAKKLIVEAIERYKTQG

Sequences:

>Translated_177_residues
MRIDAISIGKNPPDDINVIVEVPVGGHPIKYEMDKDAGALIVDRFLYTPMTYPGNYGFVPHTLSDDGDPIDVLICNTRPL
VPGCVINVRPIGVMIMEDDGGKDEKILAVPAPKLTQRYDKVHNYTDLPEITLKQIEHFFEHYKDLEPGKWVKMGGWQDVD
VAKKLIVEAIERYKTQG
>Mature_177_residues
MRIDAISIGKNPPDDINVIVEVPVGGHPIKYEMDKDAGALIVDRFLYTPMTYPGNYGFVPHTLSDDGDPIDVLICNTRPL
VPGCVINVRPIGVMIMEDDGGKDEKILAVPAPKLTQRYDKVHNYTDLPEITLKQIEHFFEHYKDLEPGKWVKMGGWQDVD
VAKKLIVEAIERYKTQG

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=176, Percent_Identity=52.8409090909091, Blast_Score=201, Evalue=2e-53,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_AGRT5 (Q8UC37)

Other databases:

- EMBL:   AE007869
- PIR:   AD2903
- PIR:   F97678
- RefSeq:   NP_355598.2
- ProteinModelPortal:   Q8UC37
- SMR:   Q8UC37
- STRING:   Q8UC37
- GeneID:   1134699
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2661
- eggNOG:   COG0221
- HOGENOM:   HBG529150
- OMA:   EHFFEHY
- PhylomeDB:   Q8UC37
- ProtClustDB:   PRK01250
- BioCyc:   ATUM176299-1:ATU2661-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 19902; Mature: 19902

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDAISIGKNPPDDINVIVEVPVGGHPIKYEMDKDAGALIVDRFLYTPMTYPGNYGFVP
CEEEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
HTLSDDGDPIDVLICNTRPLVPGCVINVRPIGVMIMEDDGGKDEKILAVPAPKLTQRYDK
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEECCHHHHHHHHH
VHNYTDLPEITLKQIEHFFEHYKDLEPGKWVKMGGWQDVDVAKKLIVEAIERYKTQG
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIDAISIGKNPPDDINVIVEVPVGGHPIKYEMDKDAGALIVDRFLYTPMTYPGNYGFVP
CEEEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
HTLSDDGDPIDVLICNTRPLVPGCVINVRPIGVMIMEDDGGKDEKILAVPAPKLTQRYDK
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEECCHHHHHHHHH
VHNYTDLPEITLKQIEHFFEHYKDLEPGKWVKMGGWQDVDVAKKLIVEAIERYKTQG
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194