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The map label for this gene is cheD [H]

Identifier: 159185294

GI number: 159185294

Start: 2601286

End: 2603058

Strand: Direct

Name: cheD [H]

Synonym: Atu2618

Alternate gene names: 159185294

Gene position: 2601286-2603058 (Clockwise)

Preceding gene: 159185293

Following gene: 15889883

Centisome position: 91.54

GC content: 58.38

Gene sequence:

>1773_bases
ATGCTGGGGTTAGGAAAAAGCGCAGACAATCGAAATATGCTCGATGCGATATCCAGATCGCAGGCGGTCATAGAATTCGA
TCTCAAGGGTAATATTCTCACCGCAAACCGCAATTTCTGCATGGCGCTGGGTTATGATCTCGCAGAAATCGTCGGCAAGC
ACCATCGCATCTTCTGCGACCGGGAGATTGCCGCATCGCACGCCTATCAGGAGTTCTGGGAATCTCTTGCGCGCGGCGAA
TTTCAGGCGAAGGAGTATCGCCGCATCCGCAAGGATGGATCAGCCGTCTGGATCGAAGCATCCTACAATCCTGTCTTCCG
TTCGGGCAAACCCTACAAAGTCGTCAAGATCGCGACCGACATCACCGCCAAGAGGATCAAGGCCGTCGAAGATGCAGGCA
AGCTGGAGGCGTTATCCCGCTCTCAGGCCACCATCGAGTTTTTCCCCGACGGTACGATCATCACCGCCAATCCGAACTTC
TGCGCAACGGTGAACTACGACCTGAAGGAAATCGAGGGCAAACACCATCGCATGTTCTGTGATCCGGCCTATACGGCATC
CGCGGCTTACGCCAATTTCTGGCAGCGGCTGGCATCGGGAGAGTTCATTTCGGACGAATTTGTCCGCTATGGAAAGAACG
GCAAGGAAATATGGATCCAGGCCGCCTACAACCCGGTCCTGGATGAGGCGGGAAAAGTCGTGAAAGTGGTGAAATTCGCC
ACCGACGTGACCCCGCGCATGAGCGCCATTACTGTGCTTGCCGATGCTTTGCAGGCGCTGGCCGCGGGCGACCTCGTGCA
GCGCCTCGACACCAGCTTCGTGCCCAGCATGGAGAAGCTGCGTGCGGACTTTAATGAGGTCGTCGGCAAGCTACAGGCCA
CCATGCAGACGATCTCCCACAATGCCTCGACAATCGCCTCCGGCTCGGGCGAAATCCGCATCGCCGCCGATCAACTTTCG
CAACGCACCGAACAACAGGCGGCCTCGCTGGAAGAAACTGCGGCCGCTCTCGAAGAAATCACCACCACCGTGACCGATGC
CAGCCAGCGTGCCGCCGAGGCGGGCAAGCTGGTGTTGCGGACGAGGGAACATGCCGAACATTCCGGCGACGTCGTTCAGC
AGGCGATTTCCGCCATGGACGCGATTTCGCGTTCCTCCGGCGAAATCACCAATATCATCGGCGTGATCGACGACATCGCC
TTCCAGACCAATCTTCTGGCGCTGAATGCAGGGGTCGAAGCCGCCCGCGCCGGGGAGGCCGGCAAGGGTTTTGCCGTTGT
GGCGCAGGAAGTTCGCGAGCTGGCGCAACGCTCCGCCGTCGCGGCCAAGGAAATCAAATCGCTTATCAACACCTCCCGCG
AACAGGTCGCCAACGGCGTCGATCTCGTCGGCAGAACCGGTGGGGCCTTGCGGGATATTCAGTCGCAGATGGGCGAAATC
GATATCAATGTCTCGGCAATCGTCGAGGCATCGCGCGAACAGGCGAACGGGCTGAAGGAAATCAATCAGGCCGTCAACGT
CATGGATCAGGCGACCCAGAAAAATGCCGCCATGGTGGAAGAAACCACTGCCGCCAGCCACGGCCTCGCCAGTGAGGCCG
ACAACCTCTATGTATTGCTGCGACAGTTCAAAATATCCGGCGACGGACAGATATCATCTGCCCAGCCCATCGATAAAAAA
GCCGCCAGCATATCCCGGCTACCGACACCTCAGCCGCGATATGCCACGGCAAGGGCGCATGGCAATGCGGCAGCCGAATG
GGCGGAATTCTAA

Upstream 100 bases:

>100_bases
GCCCATGGCGGCAAAACCTGTTCGTTGTTCAACATGATACGGCGCGGACCGCACCTTGGGTGCGGCGAGCCGCCCGTGGA
CCGATATTTGGGGGACGTTA

Downstream 100 bases:

>100_bases
ACCCGCCTATGCCGAAGCCAACCGCCGAGGCTATAGAATAATACGGTCCGCACGGGTGAAGATCTCGAAGTCTTCACCCC
GGACCAACGCAACAAGCGTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MLGLGKSADNRNMLDAISRSQAVIEFDLKGNILTANRNFCMALGYDLAEIVGKHHRIFCDREIAASHAYQEFWESLARGE
FQAKEYRRIRKDGSAVWIEASYNPVFRSGKPYKVVKIATDITAKRIKAVEDAGKLEALSRSQATIEFFPDGTIITANPNF
CATVNYDLKEIEGKHHRMFCDPAYTASAAYANFWQRLASGEFISDEFVRYGKNGKEIWIQAAYNPVLDEAGKVVKVVKFA
TDVTPRMSAITVLADALQALAAGDLVQRLDTSFVPSMEKLRADFNEVVGKLQATMQTISHNASTIASGSGEIRIAADQLS
QRTEQQAASLEETAAALEEITTTVTDASQRAAEAGKLVLRTREHAEHSGDVVQQAISAMDAISRSSGEITNIIGVIDDIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAVAAKEIKSLINTSREQVANGVDLVGRTGGALRDIQSQMGEI
DINVSAIVEASREQANGLKEINQAVNVMDQATQKNAAMVEETTAASHGLASEADNLYVLLRQFKISGDGQISSAQPIDKK
AASISRLPTPQPRYATARAHGNAAAEWAEF

Sequences:

>Translated_590_residues
MLGLGKSADNRNMLDAISRSQAVIEFDLKGNILTANRNFCMALGYDLAEIVGKHHRIFCDREIAASHAYQEFWESLARGE
FQAKEYRRIRKDGSAVWIEASYNPVFRSGKPYKVVKIATDITAKRIKAVEDAGKLEALSRSQATIEFFPDGTIITANPNF
CATVNYDLKEIEGKHHRMFCDPAYTASAAYANFWQRLASGEFISDEFVRYGKNGKEIWIQAAYNPVLDEAGKVVKVVKFA
TDVTPRMSAITVLADALQALAAGDLVQRLDTSFVPSMEKLRADFNEVVGKLQATMQTISHNASTIASGSGEIRIAADQLS
QRTEQQAASLEETAAALEEITTTVTDASQRAAEAGKLVLRTREHAEHSGDVVQQAISAMDAISRSSGEITNIIGVIDDIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAVAAKEIKSLINTSREQVANGVDLVGRTGGALRDIQSQMGEI
DINVSAIVEASREQANGLKEINQAVNVMDQATQKNAAMVEETTAASHGLASEADNLYVLLRQFKISGDGQISSAQPIDKK
AASISRLPTPQPRYATARAHGNAAAEWAEF
>Mature_590_residues
MLGLGKSADNRNMLDAISRSQAVIEFDLKGNILTANRNFCMALGYDLAEIVGKHHRIFCDREIAASHAYQEFWESLARGE
FQAKEYRRIRKDGSAVWIEASYNPVFRSGKPYKVVKIATDITAKRIKAVEDAGKLEALSRSQATIEFFPDGTIITANPNF
CATVNYDLKEIEGKHHRMFCDPAYTASAAYANFWQRLASGEFISDEFVRYGKNGKEIWIQAAYNPVLDEAGKVVKVVKFA
TDVTPRMSAITVLADALQALAAGDLVQRLDTSFVPSMEKLRADFNEVVGKLQATMQTISHNASTIASGSGEIRIAADQLS
QRTEQQAASLEETAAALEEITTTVTDASQRAAEAGKLVLRTREHAEHSGDVVQQAISAMDAISRSSGEITNIIGVIDDIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAVAAKEIKSLINTSREQVANGVDLVGRTGGALRDIQSQMGEI
DINVSAIVEASREQANGLKEINQAVNVMDQATQKNAAMVEETTAASHGLASEADNLYVLLRQFKISGDGQISSAQPIDKK
AASISRLPTPQPRYATARAHGNAAAEWAEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=263, Percent_Identity=46.3878326996198, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1788194, Length=294, Percent_Identity=41.4965986394558, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788195, Length=338, Percent_Identity=39.0532544378698, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787690, Length=292, Percent_Identity=40.0684931506849, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=39.3305439330544, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63889; Mature: 63889

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLGKSADNRNMLDAISRSQAVIEFDLKGNILTANRNFCMALGYDLAEIVGKHHRIFCD
CCCCCCCCCCCHHHHHHHCCCEEEEEECCCCEEECCCCEEEEECCCHHHHHCCHHEEEEC
REIAASHAYQEFWESLARGEFQAKEYRRIRKDGSAVWIEASYNPVFRSGKPYKVVKIATD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEEHH
ITAKRIKAVEDAGKLEALSRSQATIEFFPDGTIITANPNFCATVNYDLKEIEGKHHRMFC
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCEEEEECCCHHHCCCCCCEEEE
DPAYTASAAYANFWQRLASGEFISDEFVRYGKNGKEIWIQAAYNPVLDEAGKVVKVVKFA
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
TDVTPRMSAITVLADALQALAAGDLVQRLDTSFVPSMEKLRADFNEVVGKLQATMQTISH
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NASTIASGSGEIRIAADQLSQRTEQQAASLEETAAALEEITTTVTDASQRAAEAGKLVLR
CCHHEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TREHAEHSGDVVQQAISAMDAISRSSGEITNIIGVIDDIAFQTNLLALNAGVEAARAGEA
HHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCC
GKGFAVVAQEVRELAQRSAVAAKEIKSLINTSREQVANGVDLVGRTGGALRDIQSQMGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHCCCCCHHHHHHHHHCCC
DINVSAIVEASREQANGLKEINQAVNVMDQATQKNAAMVEETTAASHGLASEADNLYVLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEE
RQFKISGDGQISSAQPIDKKAASISRLPTPQPRYATARAHGNAAAEWAEF
HHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEHHCCCCCCHHHHCC
>Mature Secondary Structure
MLGLGKSADNRNMLDAISRSQAVIEFDLKGNILTANRNFCMALGYDLAEIVGKHHRIFCD
CCCCCCCCCCCHHHHHHHCCCEEEEEECCCCEEECCCCEEEEECCCHHHHHCCHHEEEEC
REIAASHAYQEFWESLARGEFQAKEYRRIRKDGSAVWIEASYNPVFRSGKPYKVVKIATD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEEHH
ITAKRIKAVEDAGKLEALSRSQATIEFFPDGTIITANPNFCATVNYDLKEIEGKHHRMFC
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCEEEEECCCHHHCCCCCCEEEE
DPAYTASAAYANFWQRLASGEFISDEFVRYGKNGKEIWIQAAYNPVLDEAGKVVKVVKFA
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
TDVTPRMSAITVLADALQALAAGDLVQRLDTSFVPSMEKLRADFNEVVGKLQATMQTISH
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NASTIASGSGEIRIAADQLSQRTEQQAASLEETAAALEEITTTVTDASQRAAEAGKLVLR
CCHHEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TREHAEHSGDVVQQAISAMDAISRSSGEITNIIGVIDDIAFQTNLLALNAGVEAARAGEA
HHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCC
GKGFAVVAQEVRELAQRSAVAAKEIKSLINTSREQVANGVDLVGRTGGALRDIQSQMGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHCCCCCHHHHHHHHHCCC
DINVSAIVEASREQANGLKEINQAVNVMDQATQKNAAMVEETTAASHGLASEADNLYVLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEE
RQFKISGDGQISSAQPIDKKAASISRLPTPQPRYATARAHGNAAAEWAEF
HHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]