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The map label for this gene is benK [H]

Identifier: 159185253

GI number: 159185253

Start: 2498361

End: 2499710

Strand: Reverse

Name: benK [H]

Synonym: Atu2525

Alternate gene names: 159185253

Gene position: 2499710-2498361 (Counterclockwise)

Preceding gene: 15889791

Following gene: 15889785

Centisome position: 87.97

GC content: 61.11

Gene sequence:

>1350_bases
ATGCAGGGACGGGGAGACGCTGATCCATACCGGATGGCGCGTTCGTGCGTGAAAGGGAGGAATATGTCCACGAATTATCT
GAGCGCCGCTTCAGTGCGGACGAAGAACCCGGCTGGCGTCATCGCGACATGCGGCCTGATGATCATGTTCGACGGGTACG
ACCTGGTCGTTTATGGCGCGGTCGCCCCGGCGCTGCTGAAAGAAAGCACCTGGGCGCTTAACCCGGCCATGGTCGGGCGC
GCCGCCGCCTTGACGCTGGTGGGCATGCTGCTCGGCGCACTGTTTGCCGGCACCATGGCCGACCGTATCGGCCGCCGGAA
GGTGGTTCTCTTAAGCCTCGCCGGATTTTCGGCGATGATGATCGCCTCGGCCATGACGCCGAACTTTCTCGCCTTCGAAA
TCACCCGCTTTTTTGCCGGCCTCGGACTTGGCGCGCTGTTGCCGACGGTTACTGCGCTGGTGCTGGAGTTTTCGCCGCCG
CAACGCAGGGCGCAGGCCAATTCCCTGTCCTTCCTCGGTTATCTCATCGGCGGCATCATTTCCGGCATCCTGGGCATGCT
ACTTCTGGAGAGTTATGGCTGGCGGCCATTGATGCTGATCGGCGGCCTGCCGCTCATCCTGCTGCCGATCTTCATGCGCT
TCCTGCCGGAATCGCCGGAGTGGCTGGCGAGCAAAGGCCGGCAGGCGGAGGCCGACGGCATTTGCGACAGTTATGGTCTG
CAACGCATCGTACCCCATGCAAAAATGCAGAAGGGTGGCGTCGGCGCGTTGTTTTCCGAAGGCCGGCTGGCTTCGACGCT
GAATGCCTGGGGCATTCACTTCTGCTCGCTGCTGCTCACCTTCGGCATGGTCAACTGGTTGCCCACCATCATGAACAAGA
TGGGTTATGACATCAGTTCGGCGCTCAGCTTTTCCGTCATGCTCAATGTCGGCGCCGCCATCGGCATCCTTATCGGTGGA
CGCTTTGCGGATAAGGGCAACGTCAAGGTGGTGGTGGCGATCCTGTTTGCCGTCGGCGCCGCATCGATCTTCGCCCTGAC
TGCCAACAAGGGACCGCTTCTTTATGTTTTCGTGGCGCTTGCGGGTGCCGGAACCATCGGAACGCAGATTCTCGCCAATG
TCCTGGTAGGACGGCTTTATCCCGTCCATATTCGAGGCACTGGTCTCGGCTTTTCGCTGGCGGTCGGGCGGCTTGGCGGC
ATTGCTGGGCCGATGATCGGCGGCCTGGTGCTGCAAAGGGGTCTGGCGCCGGAGTGGAATTTCTACATTTTTGGCTCGGT
CGCGGTCGTTGGGCTGATGCTCACAGTGTTGACCCTGCTTTACCGCACATCGGGCGACGCACGGGTTTGA

Upstream 100 bases:

>100_bases
ATGCAACATTTAATTTATGGCGAGTGATATCGGCGACGTGTGGCTTGACAGGAGCAAGGCACATATCAGGGTGGAGCCCG
CCGGACACTCACGGAGGATA

Downstream 100 bases:

>100_bases
TAACAGGCTATGGCCGCAGGATCGTGAACCTGCGGCCATCGCAAACCTAATGCGGCAGGACATGCGGTCTCAGAAAAACA
ATCCGTCAGCCCCTGCGTCC

Product: MFS permease

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQGRGDADPYRMARSCVKGRNMSTNYLSAASVRTKNPAGVIATCGLMIMFDGYDLVVYGAVAPALLKESTWALNPAMVGR
AAALTLVGMLLGALFAGTMADRIGRRKVVLLSLAGFSAMMIASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSPP
QRRAQANSLSFLGYLIGGIISGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESPEWLASKGRQAEADGICDSYGL
QRIVPHAKMQKGGVGALFSEGRLASTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISSALSFSVMLNVGAAIGILIGG
RFADKGNVKVVVAILFAVGAASIFALTANKGPLLYVFVALAGAGTIGTQILANVLVGRLYPVHIRGTGLGFSLAVGRLGG
IAGPMIGGLVLQRGLAPEWNFYIFGSVAVVGLMLTVLTLLYRTSGDARV

Sequences:

>Translated_449_residues
MQGRGDADPYRMARSCVKGRNMSTNYLSAASVRTKNPAGVIATCGLMIMFDGYDLVVYGAVAPALLKESTWALNPAMVGR
AAALTLVGMLLGALFAGTMADRIGRRKVVLLSLAGFSAMMIASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSPP
QRRAQANSLSFLGYLIGGIISGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESPEWLASKGRQAEADGICDSYGL
QRIVPHAKMQKGGVGALFSEGRLASTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISSALSFSVMLNVGAAIGILIGG
RFADKGNVKVVVAILFAVGAASIFALTANKGPLLYVFVALAGAGTIGTQILANVLVGRLYPVHIRGTGLGFSLAVGRLGG
IAGPMIGGLVLQRGLAPEWNFYIFGSVAVVGLMLTVLTLLYRTSGDARV
>Mature_449_residues
MQGRGDADPYRMARSCVKGRNMSTNYLSAASVRTKNPAGVIATCGLMIMFDGYDLVVYGAVAPALLKESTWALNPAMVGR
AAALTLVGMLLGALFAGTMADRIGRRKVVLLSLAGFSAMMIASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSPP
QRRAQANSLSFLGYLIGGIISGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESPEWLASKGRQAEADGICDSYGL
QRIVPHAKMQKGGVGALFSEGRLASTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISSALSFSVMLNVGAAIGILIGG
RFADKGNVKVVVAILFAVGAASIFALTANKGPLLYVFVALAGAGTIGTQILANVLVGRLYPVHIRGTGLGFSLAVGRLGG
IAGPMIGGLVLQRGLAPEWNFYIFGSVAVVGLMLTVLTLLYRTSGDARV

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=202, Percent_Identity=28.7128712871287, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI24308167, Length=399, Percent_Identity=24.0601503759398, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI166064021, Length=383, Percent_Identity=26.1096605744125, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI262399383, Length=163, Percent_Identity=29.4478527607362, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI73695465, Length=168, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI90669191, Length=377, Percent_Identity=23.8726790450928, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI216548223, Length=177, Percent_Identity=25.9887005649718, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI24497497, Length=346, Percent_Identity=23.4104046242775, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4507005, Length=348, Percent_Identity=24.4252873563218, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI166197673, Length=375, Percent_Identity=24.8, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI24497478, Length=152, Percent_Identity=34.8684210526316, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI24497480, Length=152, Percent_Identity=34.8684210526316, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI24497476, Length=152, Percent_Identity=34.8684210526316, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI20070188, Length=152, Percent_Identity=34.8684210526316, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI213021148, Length=235, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI31542327, Length=345, Percent_Identity=25.7971014492754, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87081723, Length=378, Percent_Identity=32.2751322751323, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788074, Length=372, Percent_Identity=30.3763440860215, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082231, Length=409, Percent_Identity=25.6723716381418, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788068, Length=401, Percent_Identity=26.4339152119701, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786229, Length=384, Percent_Identity=24.7395833333333, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082159, Length=372, Percent_Identity=28.7634408602151, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082404, Length=374, Percent_Identity=22.4598930481283, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32564663, Length=433, Percent_Identity=25.1732101616628, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560496, Length=436, Percent_Identity=22.7064220183486, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17542342, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319718, Length=165, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640198, Length=297, Percent_Identity=24.5791245791246, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640196, Length=297, Percent_Identity=24.5791245791246, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640200, Length=297, Percent_Identity=24.5791245791246, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24668456, Length=414, Percent_Identity=25.1207729468599, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24668440, Length=387, Percent_Identity=24.8062015503876, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922616, Length=344, Percent_Identity=22.9651162790698, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47307; Mature: 47307

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGRGDADPYRMARSCVKGRNMSTNYLSAASVRTKNPAGVIATCGLMIMFDGYDLVVYGA
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHHCCEEEEECCCCEEEEHH
VAPALLKESTWALNPAMVGRAAALTLVGMLLGALFAGTMADRIGRRKVVLLSLAGFSAMM
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
IASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSPPQRRAQANSLSFLGYLIGGII
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESPEWLASKGRQAEADGICDSYGL
HHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHCH
QRIVPHAKMQKGGVGALFSEGRLASTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISS
HHHCCCHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALSFSVMLNVGAAIGILIGGRFADKGNVKVVVAILFAVGAASIFALTANKGPLLYVFVAL
HHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
AGAGTIGTQILANVLVGRLYPVHIRGTGLGFSLAVGRLGGIAGPMIGGLVLQRGLAPEWN
HCCCHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
FYIFGSVAVVGLMLTVLTLLYRTSGDARV
EEEEHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQGRGDADPYRMARSCVKGRNMSTNYLSAASVRTKNPAGVIATCGLMIMFDGYDLVVYGA
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHHCCEEEEECCCCEEEEHH
VAPALLKESTWALNPAMVGRAAALTLVGMLLGALFAGTMADRIGRRKVVLLSLAGFSAMM
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
IASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSPPQRRAQANSLSFLGYLIGGII
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESPEWLASKGRQAEADGICDSYGL
HHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHCH
QRIVPHAKMQKGGVGALFSEGRLASTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISS
HHHCCCHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALSFSVMLNVGAAIGILIGGRFADKGNVKVVVAILFAVGAASIFALTANKGPLLYVFVAL
HHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
AGAGTIGTQILANVLVGRLYPVHIRGTGLGFSLAVGRLGGIAGPMIGGLVLQRGLAPEWN
HCCCHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
FYIFGSVAVVGLMLTVLTLLYRTSGDARV
EEEEHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]