Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 159185209

GI number: 159185209

Start: 2394505

End: 2395623

Strand: Reverse

Name: livK [C]

Synonym: Atu2422

Alternate gene names: 159185209

Gene position: 2395623-2394505 (Counterclockwise)

Preceding gene: 159185442

Following gene: 15889691

Centisome position: 84.31

GC content: 59.7

Gene sequence:

>1119_bases
ATGAAGAAGTCTCTTCTTTCCGCTGTTGCGCTGACCGCCATGGTCGCGTTTGGCGGTTCGGCCTGGGCCGATGTCGTGAT
CGCTGTCGGCGCACCGCTGACCGGCCCGAACGCTGCTTTCGGCGCTCAGATCCAGAAGGGTGCCGAACAGGCTGCGAAAG
ACATCAATGCTGCCGGCGGTATCAATGGCGAGCAGATTAAGATCGTGCTGGGCGACGACGTATCCGACCCCAAGCAGGGT
ATTTCGGTTGCCAACAAATTCGTTGCTGACGGCGTGAAATTCGTTGTCGGTCACTTCAACTCGGGTGTTTCCATTCCGGC
ATCGGAAGTTTATGCCGAAAACGGCATTCTCGAAATCACGCCCGCTGCGACCAACCCGGTCTTTACCGAGCGTGGCCTGT
GGAACACCTTCCGCACCTGCGGCCGTGACGACCAGCAGGGCGGCATTGCCGGCAAGTACCTGGCCGATCATTTCAAGGAC
GCCAAGGTCGCCATCATTCACGACAAGACGCCTTATGGTCAGGGTCTTGCCGATGAAACCAAAAAGGCTGCCAATGCTGC
CGGCGTGACTGAGGTCATGTATGAAGGCGTCAACGTCGGCGACAAGGACTTCTCCGCGCTGATCTCGAAGATGAAGGAAG
CCGGCGTTTCCATCATCTACTGGGGCGGCCTGCACACCGAAGCCGGCCTGATCATCCGCCAGGCGGCTGACCAGGGTCTG
AAGGCCAAGCTCGTTTCGGGCGACGGTATTGTCTCGAACGAACTTGCTTCCATCGCCGGCGACGCCGTCGAGGGCACGCT
GAACACCTTCGGCCCTGATCCGACGCTGCGCCCGGAAAACAAGGAACTGGTAGAGAAGTTCAAGGCCGCCGGCTTCAACC
CGGAAGCCTACACGCTCTACTCCTATGCCGCGATGCAGGCGATTGCAGGCGCAGCGAAGGCTGCGGGTTCCGTGGAGCCG
GAAAAGGTTGCCGAAGCCCTGAAGAAGGGCTCCTTCCCGACCGCACTCGGCGAAATCTCCTTCGATGAGAAGGGCGACCC
GAAGCTTCCCGGCTACGTCATGTACGAATGGAAGAAGGGTCCGGACGGCAAGTTCACCTACATCCAGCAGGGCAGCTAA

Upstream 100 bases:

>100_bases
TGCACAATGCTCGTCAGAGTGGAACGGTTTCTGTTCGGTTAAGGTGGGTATCGAACAGGTCCTTGCAATCAACCCATCCA
AGGAACTGGGAGTTAAAGTA

Downstream 100 bases:

>100_bases
GCCTTCAGCGATACACTATCGAAGCCCGGCAGCGATGCCGGGCTTTTTGTTTTTGACGACACTCTGCTGCTTTGCCTGCC
ACACTGGAGACAACAAGGCG

Product: ABC transporter, substrate binding protein (amino acid)

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKKSLLSAVALTAMVAFGGSAWADVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQG
ISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKD
AKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGL
KAKLVSGDGIVSNELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLYSYAAMQAIAGAAKAAGSVEP
EKVAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEWKKGPDGKFTYIQQGS

Sequences:

>Translated_372_residues
MKKSLLSAVALTAMVAFGGSAWADVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQG
ISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKD
AKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGL
KAKLVSGDGIVSNELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLYSYAAMQAIAGAAKAAGSVEP
EKVAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEWKKGPDGKFTYIQQGS
>Mature_372_residues
MKKSLLSAVALTAMVAFGGSAWADVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQG
ISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKD
AKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGL
KAKLVSGDGIVSNELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLYSYAAMQAIAGAAKAAGSVEP
EKVAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEWKKGPDGKFTYIQQGS

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=359, Percent_Identity=40.3899721448468, Blast_Score=265, Evalue=5e-72,
Organism=Escherichia coli, GI48994941, Length=345, Percent_Identity=40.5797101449275, Blast_Score=259, Evalue=2e-70,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 38809; Mature: 38809

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLLSAVALTAMVAFGGSAWADVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGG
CCHHHHHHHHHHHHHHHCCCHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
INGEQIKIVLGDDVSDPKQGISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEIT
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHCCCCEEEE
PAATNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADET
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
KKAANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGL
HHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCC
KAKLVSGDGIVSNELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLY
EEEEECCCCCHHHHHHHHHCHHHHCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
SYAAMQAIAGAAKAAGSVEPEKVAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEWKKG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
PDGKFTYIQQGS
CCCCEEEEECCC
>Mature Secondary Structure
MKKSLLSAVALTAMVAFGGSAWADVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGG
CCHHHHHHHHHHHHHHHCCCHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
INGEQIKIVLGDDVSDPKQGISVANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEIT
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHCCCCEEEE
PAATNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADET
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
KKAANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGL
HHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCC
KAKLVSGDGIVSNELASIAGDAVEGTLNTFGPDPTLRPENKELVEKFKAAGFNPEAYTLY
EEEEECCCCCHHHHHHHHHCHHHHCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
SYAAMQAIAGAAKAAGSVEPEKVAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEWKKG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
PDGKFTYIQQGS
CCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA