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The map label for this gene is ureG

Identifier: 159185193

GI number: 159185193

Start: 2369298

End: 2369909

Strand: Reverse

Name: ureG

Synonym: Atu2396

Alternate gene names: 159185193

Gene position: 2369909-2369298 (Counterclockwise)

Preceding gene: 159185194

Following gene: 15889666

Centisome position: 83.4

GC content: 58.99

Gene sequence:

>612_bases
ATGAAATCGGGTAATGGTCCGCTGCGCGTCGGCATTGGCGGGCCGGTAGGTTCCGGCAAGACGGCGTTGACGGAAAAGCT
CTGCAAGGCGATGAGCGGCGATTATTCCGTCGCCGTCGTCACCAATGATATCTATACCAAGGAAGATGCCGAGGCGTTGG
TGCGCATGCAGGCGTTGCCATCCGAGCGTATCGTCGGTGTGGAGACAGGCGGTTGCCCGCATACCGCCATCCGCGAGGAT
GCGACGATCAATCTGCAGGCGATTGCCGGGCTTAATGCGCAGTTTCCCGATCTCGATGTTGTCTTCATCGAATCCGGCGG
TGACAATCTCGCCGCGACCTTTTCGCCCGATCTTGCCGATATCACCATCTATGTGATCTCCGTCTGCCAGGGCGAGGAGA
TTCCGCGCAAGGGCGGGCCGGGCATCACCCGCTCGGACCTGCTGGTCATCAACAAGAAGGACCTTGCGCCTTATGTCGGT
GCCGATCTGACTGTGATGGACAGCGATGCGACGCGGATGCGCAACGCCATGCCGTTCGTTTTTACCGATATGAAACGGGG
CGATGGCGTCGATCGTATCGTCGGTTTCCTGAAAGAGCAGGGTGGTCTGTGA

Upstream 100 bases:

>100_bases
GGGGAGAAGAAACTGGCGGCACGGTTCTTGCTTGCTCTTGAAGCGTTGGTCCAAGGCTTTACGGTAGGAAATACCAAAGC
ATGATGAAGGGAACAGAGTG

Downstream 100 bases:

>100_bases
GCCATGAATGCACCGCTGCGTTTTGGCCCCTATGCCGTGTCCCGGTTCGTTGATGGCGTCTACAAGGCACCTGTCGGTCA
TCTCATCCACCGGCAGGGCG

Product: urease accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKSGNGPLRVGIGGPVGSGKTALTEKLCKAMSGDYSVAVVTNDIYTKEDAEALVRMQALPSERIVGVETGGCPHTAIRED
ATINLQAIAGLNAQFPDLDVVFIESGGDNLAATFSPDLADITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVG
ADLTVMDSDATRMRNAMPFVFTDMKRGDGVDRIVGFLKEQGGL

Sequences:

>Translated_203_residues
MKSGNGPLRVGIGGPVGSGKTALTEKLCKAMSGDYSVAVVTNDIYTKEDAEALVRMQALPSERIVGVETGGCPHTAIRED
ATINLQAIAGLNAQFPDLDVVFIESGGDNLAATFSPDLADITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVG
ADLTVMDSDATRMRNAMPFVFTDMKRGDGVDRIVGFLKEQGGL
>Mature_203_residues
MKSGNGPLRVGIGGPVGSGKTALTEKLCKAMSGDYSVAVVTNDIYTKEDAEALVRMQALPSERIVGVETGGCPHTAIRED
ATINLQAIAGLNAQFPDLDVVFIESGGDNLAATFSPDLADITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVG
ADLTVMDSDATRMRNAMPFVFTDMKRGDGVDRIVGFLKEQGGL

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_AGRT5 (Q7CX57)

Other databases:

- EMBL:   AE007869
- RefSeq:   NP_355348.2
- ProteinModelPortal:   Q7CX57
- SMR:   Q7CX57
- STRING:   Q7CX57
- GeneID:   1134434
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2396
- eggNOG:   COG0378
- HOGENOM:   HBG364734
- OMA:   DDIPRKG
- PhylomeDB:   Q7CX57
- ProtClustDB:   CLSK864148
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 21434; Mature: 21434

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGNGPLRVGIGGPVGSGKTALTEKLCKAMSGDYSVAVVTNDIYTKEDAEALVRMQALP
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCC
SERIVGVETGGCPHTAIREDATINLQAIAGLNAQFPDLDVVFIESGGDNLAATFSPDLAD
CCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCHHH
ITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVGADLTVMDSDATRMRNAMPFV
EEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCEEEECCCHHHHHCCCCEE
FTDMKRGDGVDRIVGFLKEQGGL
EECCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSGNGPLRVGIGGPVGSGKTALTEKLCKAMSGDYSVAVVTNDIYTKEDAEALVRMQALP
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCC
SERIVGVETGGCPHTAIREDATINLQAIAGLNAQFPDLDVVFIESGGDNLAATFSPDLAD
CCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCHHH
ITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVGADLTVMDSDATRMRNAMPFV
EEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCEEEECCCHHHHHCCCCEE
FTDMKRGDGVDRIVGFLKEQGGL
EECCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194