Click here to switch to the map view.

The map label for this gene is sinR [H]

Identifier: 159185192

GI number: 159185192

Start: 2367708

End: 2368397

Strand: Direct

Name: sinR [H]

Synonym: Atu2394

Alternate gene names: 159185192

Gene position: 2367708-2368397 (Clockwise)

Preceding gene: 15889664

Following gene: 159185208

Centisome position: 83.32

GC content: 61.45

Gene sequence:

>690_bases
ATGGACGTGAACAAGACCGTGAAGCTGAGCAACAGGGACAGGAACATTCTGCTGCGTGCACCCCTGATCGGGGTTGCCGA
CGACGCGGCCGCGCTGAAGATGATGGAGGCGGCGACCATCACCAATGTCAACGCCCGCCACGTCCTCTTCAAGGAAGGCG
AAACGGCGCAGCATTTTTATTGCGTGCTATCGGGTTATATCAGGCTTTATCGGCTGGACCGGCACGGGCGTGAGGCGGAT
GTGCGCGTCAGCGGACCCGGCGATACCTTCAACGAATGCCTGATCTTCGGCAGCGATACCTATCGTTACAGCGCGCAGGC
GGCTGAAAGCTGCACAGTGGCGCGTTTCGAGCTGGCAAGAATCCGAACCCTGATCGATCAGGAGCCGGCAATCGCCAAGG
CCGTCATGCGCTGCCTTTCCAACAGCCTGCTGGCGACCATGGACTGCATCGCCAACGACCGGCTGCAGACGGCACCACAA
CGCGTCGCCCATTACCTCATCAACCAGGGCCCGCGCGATGCGACATCCTTTTCGCTGCGGCTGCCCTTCCAGAAGAGCCT
GCTGGCCGGCAAGCTCGGCCTTGCCCCGGAAGCCCTGTCGCGCGCTTTCTCGGCACTGAAGAAGTCAGGCGTCACGGTGC
GCGGCCGCATCGTGCAGGTTAATGACGTCGCGGCATTAAAGCAGATCTGA

Upstream 100 bases:

>100_bases
AAATGCGATGAGTTCTTTGCAGATAGGCGTGAGGGAGAAGGAACTTCCCCGGTTTCGTATCGCTTCGGACGGCCCGGCAA
AAGGTTTGAGCGGGAGCCGG

Downstream 100 bases:

>100_bases
AAACACCGGGAGAGGATGAAGGGCGGTATGCCAACCGGCATGCCGCCCTTCTGCATGACTGAAAGCGGAAAATCAGCCCG
GCTGCGGCACGAAGCGGAAG

Product: regulator of biofilm formation, Fnr family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MDVNKTVKLSNRDRNILLRAPLIGVADDAAALKMMEAATITNVNARHVLFKEGETAQHFYCVLSGYIRLYRLDRHGREAD
VRVSGPGDTFNECLIFGSDTYRYSAQAAESCTVARFELARIRTLIDQEPAIAKAVMRCLSNSLLATMDCIANDRLQTAPQ
RVAHYLINQGPRDATSFSLRLPFQKSLLAGKLGLAPEALSRAFSALKKSGVTVRGRIVQVNDVAALKQI

Sequences:

>Translated_229_residues
MDVNKTVKLSNRDRNILLRAPLIGVADDAAALKMMEAATITNVNARHVLFKEGETAQHFYCVLSGYIRLYRLDRHGREAD
VRVSGPGDTFNECLIFGSDTYRYSAQAAESCTVARFELARIRTLIDQEPAIAKAVMRCLSNSLLATMDCIANDRLQTAPQ
RVAHYLINQGPRDATSFSLRLPFQKSLLAGKLGLAPEALSRAFSALKKSGVTVRGRIVQVNDVAALKQI
>Mature_229_residues
MDVNKTVKLSNRDRNILLRAPLIGVADDAAALKMMEAATITNVNARHVLFKEGETAQHFYCVLSGYIRLYRLDRHGREAD
VRVSGPGDTFNECLIFGSDTYRYSAQAAESCTVARFELARIRTLIDQEPAIAKAVMRCLSNSLLATMDCIANDRLQTAPQ
RVAHYLINQGPRDATSFSLRLPFQKSLLAGKLGLAPEALSRAFSALKKSGVTVRGRIVQVNDVAALKQI

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=192, Percent_Identity=27.0833333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25224; Mature: 25224

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVNKTVKLSNRDRNILLRAPLIGVADDAAALKMMEAATITNVNARHVLFKEGETAQHFY
CCCCCEEEECCCCCEEEEECCCEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
CVLSGYIRLYRLDRHGREADVRVSGPGDTFNECLIFGSDTYRYSAQAAESCTVARFELAR
HHHHHHHHEEEECCCCCCCEEEEECCCCCCCCEEEECCCCCEECHHHHCCHHHHHHHHHH
IRTLIDQEPAIAKAVMRCLSNSLLATMDCIANDRLQTAPQRVAHYLINQGPRDATSFSLR
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
LPFQKSLLAGKLGLAPEALSRAFSALKKSGVTVRGRIVQVNDVAALKQI
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHCC
>Mature Secondary Structure
MDVNKTVKLSNRDRNILLRAPLIGVADDAAALKMMEAATITNVNARHVLFKEGETAQHFY
CCCCCEEEECCCCCEEEEECCCEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
CVLSGYIRLYRLDRHGREADVRVSGPGDTFNECLIFGSDTYRYSAQAAESCTVARFELAR
HHHHHHHHEEEECCCCCCCEEEEECCCCCCCCEEEECCCCCEECHHHHCCHHHHHHHHHH
IRTLIDQEPAIAKAVMRCLSNSLLATMDCIANDRLQTAPQRVAHYLINQGPRDATSFSLR
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
LPFQKSLLAGKLGLAPEALSRAFSALKKSGVTVRGRIVQVNDVAALKQI
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]