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The map label for this gene is aglA [H]

Identifier: 159185146

GI number: 159185146

Start: 2269104

End: 2270768

Strand: Reverse

Name: aglA [H]

Synonym: Atu2295

Alternate gene names: 159185146

Gene position: 2270768-2269104 (Counterclockwise)

Preceding gene: 159185149

Following gene: 159185145

Centisome position: 79.91

GC content: 58.68

Gene sequence:

>1665_bases
ATGACGCTACCCCATGCCCCGGTCCACAAACCTCAAGCGCAATCGGACTGGTGGAAAGGAGCGGTGATCTATCAGGTCTA
TCCGCGCTCGTTTCAGGATACGACCGGCGACGGATATGGCGATCTGGCCGGGGTGACGAAACGTCTGCCCTATATCGCCT
CACTCGGTGTCGATGCCATCTGGCTCTCACCCTTCTTCACCTCGCCCATGGCCGATATGGGTTATGACGTTTCCGATTAT
TGCAATGTCGATCCAATGTTCGGCACGCTCGCCGATTTCGACGCCCTGATGGCCGAGGCGCACCGGCTGGGGCTGAAAGT
CATCATCGATCAGGTGATTTCGCATACGTCTGACAAACATCCGTGGTTCGTGGACAGCCGCGCGAGCCGTATCAACAGCA
AGGCGGACTGGTATGTCTGGGCCAATCCCAAACCGGATGGCACGGCACCCACCAACTGGCTTTCCGTGTTCGGCGGGCCG
GCCTGGGAGTGGGACGGGGTGCGGAAGCAATATTATATGCACAGCTTCCTCGCCTCGCAGCCGGACCTGAATTTCCACAA
TCCCGAGGTTCAGGATGCGGTGCTGGAAACCGTGCGTTTCTGGCTCGATCGTGGCGTGGACGGTTTTCGGCTCGATACCG
TCAACCACTATTTCCATGACAAGCTTTTGCGCGACAACCCGCCGCTTGTTGACGACGAAAGTTTTGGCCTCGATGCGTCC
GACGTCAATCCCTATGGCATGCAGGACCATCTCTACGACAAGACACGGCCGGAAAACGTGGCTTTCCTCAAGCGCTTTCG
TGCGCTGCTCGACGACTATGAGGGCCGCGCCACGGTGGGTGAGGTGGGGGATGGGGCTCGCTCCCTGAAAACGGTCGCGG
CCTATACATCCGGCAATGACAAACTCAACATGTGTTACACATTCGATCTGCTGGGACCGGATTTCAGTGCAAAACACCTG
CGCGGCTCGGTCGAGACATTCGGCAAGGTGGTGACGGATGGCTGGGTGTGCTGGGCCTTTTCCAACCATGATGTGGTGCG
CCATCTCAGCCGGTTTTCCGAAGGCCCCGAGGAGCAGACGCGCGTTGCGAAACTCGCCATCTGTGTTCTCGCCAGCCTGC
GTGGCTCCATATGTCTCTATCAGGGCGAGGAGCTGGGGCTGACAGAGGCCGAACTTGCCTTCGAGGATCTGCGTGATCCC
TATGGCATTCGTTTCTGGCCCGCCTTCAAGGGGCGCGACGGATGCCGCACACCGATGGTGTGGGAAACGGGCAAGCCGAA
TGCCGGGTTCTCAACTGCCGAAAAGCCTTGGCTGCCGGTGCCCTACGTGCATGCCATGCAGGCCGTGGATGCGCAGGAGC
GCAAGCCGGATTCGGTTCTCAACCATTATCGGGCCGTCCTGTCCTTCCGCAAAACCCATGGTGCGCTGCGCGACGGCGAC
ATGCATTTCATCAAGACCAATCTCGATGTGCTGGCCTTCACCCGGCAGAGGGGTGATGAAAAACTGCTGTTCGTTTTCAA
CCTGACCCGTGAGCCGGTGGAATTTCCCGTGCCAAAGGCCATGAGTGTTACGGATATCCTGCAGATGCCGGGTTTTGCGC
CGCTCTATGATGCTGGCATCGTGAAGCTCGAGGGGCTGGATGTATTTTGCGGGATCGTTGCATGA

Upstream 100 bases:

>100_bases
ACAAGGGCGATGTGGCTCGTTTGTGCATGTGCGAAGTTCCGGTTTACGCGGGCGCAAGGGCTTTATATTCTCCCGGCGTG
ACACCCTCAGGAGATCGCCG

Downstream 100 bases:

>100_bases
GCGGACAATTTGTCATCGGAAACGCCGCCGACTACCCTGATGCATGGTGCCTTTTGCGGCATCGCCTGTGGCCGGATACC
ACGCCCGCCGAACATAGGGA

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MTLPHAPVHKPQAQSDWWKGAVIYQVYPRSFQDTTGDGYGDLAGVTKRLPYIASLGVDAIWLSPFFTSPMADMGYDVSDY
CNVDPMFGTLADFDALMAEAHRLGLKVIIDQVISHTSDKHPWFVDSRASRINSKADWYVWANPKPDGTAPTNWLSVFGGP
AWEWDGVRKQYYMHSFLASQPDLNFHNPEVQDAVLETVRFWLDRGVDGFRLDTVNHYFHDKLLRDNPPLVDDESFGLDAS
DVNPYGMQDHLYDKTRPENVAFLKRFRALLDDYEGRATVGEVGDGARSLKTVAAYTSGNDKLNMCYTFDLLGPDFSAKHL
RGSVETFGKVVTDGWVCWAFSNHDVVRHLSRFSEGPEEQTRVAKLAICVLASLRGSICLYQGEELGLTEAELAFEDLRDP
YGIRFWPAFKGRDGCRTPMVWETGKPNAGFSTAEKPWLPVPYVHAMQAVDAQERKPDSVLNHYRAVLSFRKTHGALRDGD
MHFIKTNLDVLAFTRQRGDEKLLFVFNLTREPVEFPVPKAMSVTDILQMPGFAPLYDAGIVKLEGLDVFCGIVA

Sequences:

>Translated_554_residues
MTLPHAPVHKPQAQSDWWKGAVIYQVYPRSFQDTTGDGYGDLAGVTKRLPYIASLGVDAIWLSPFFTSPMADMGYDVSDY
CNVDPMFGTLADFDALMAEAHRLGLKVIIDQVISHTSDKHPWFVDSRASRINSKADWYVWANPKPDGTAPTNWLSVFGGP
AWEWDGVRKQYYMHSFLASQPDLNFHNPEVQDAVLETVRFWLDRGVDGFRLDTVNHYFHDKLLRDNPPLVDDESFGLDAS
DVNPYGMQDHLYDKTRPENVAFLKRFRALLDDYEGRATVGEVGDGARSLKTVAAYTSGNDKLNMCYTFDLLGPDFSAKHL
RGSVETFGKVVTDGWVCWAFSNHDVVRHLSRFSEGPEEQTRVAKLAICVLASLRGSICLYQGEELGLTEAELAFEDLRDP
YGIRFWPAFKGRDGCRTPMVWETGKPNAGFSTAEKPWLPVPYVHAMQAVDAQERKPDSVLNHYRAVLSFRKTHGALRDGD
MHFIKTNLDVLAFTRQRGDEKLLFVFNLTREPVEFPVPKAMSVTDILQMPGFAPLYDAGIVKLEGLDVFCGIVA
>Mature_553_residues
TLPHAPVHKPQAQSDWWKGAVIYQVYPRSFQDTTGDGYGDLAGVTKRLPYIASLGVDAIWLSPFFTSPMADMGYDVSDYC
NVDPMFGTLADFDALMAEAHRLGLKVIIDQVISHTSDKHPWFVDSRASRINSKADWYVWANPKPDGTAPTNWLSVFGGPA
WEWDGVRKQYYMHSFLASQPDLNFHNPEVQDAVLETVRFWLDRGVDGFRLDTVNHYFHDKLLRDNPPLVDDESFGLDASD
VNPYGMQDHLYDKTRPENVAFLKRFRALLDDYEGRATVGEVGDGARSLKTVAAYTSGNDKLNMCYTFDLLGPDFSAKHLR
GSVETFGKVVTDGWVCWAFSNHDVVRHLSRFSEGPEEQTRVAKLAICVLASLRGSICLYQGEELGLTEAELAFEDLRDPY
GIRFWPAFKGRDGCRTPMVWETGKPNAGFSTAEKPWLPVPYVHAMQAVDAQERKPDSVLNHYRAVLSFRKTHGALRDGDM
HFIKTNLDVLAFTRQRGDEKLLFVFNLTREPVEFPVPKAMSVTDILQMPGFAPLYDAGIVKLEGLDVFCGIVA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=511, Percent_Identity=31.7025440313112, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI61744483, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI61744481, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI61744479, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI65506891, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI61744477, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI61744475, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790687, Length=526, Percent_Identity=35.5513307984791, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1786604, Length=496, Percent_Identity=22.1774193548387, Blast_Score=89, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32565753, Length=497, Percent_Identity=24.1448692152917, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25147709, Length=557, Percent_Identity=24.5960502692998, Blast_Score=102, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321731, Length=555, Percent_Identity=35.4954954954955, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6319776, Length=555, Percent_Identity=35.4954954954955, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6322241, Length=568, Percent_Identity=35.0352112676056, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322021, Length=568, Percent_Identity=35.0352112676056, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6324416, Length=568, Percent_Identity=35.0352112676056, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321726, Length=564, Percent_Identity=34.0425531914894, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6322245, Length=565, Percent_Identity=33.4513274336283, Blast_Score=292, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24586587, Length=509, Percent_Identity=36.1493123772102, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24583745, Length=548, Percent_Identity=35.2189781021898, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24586593, Length=513, Percent_Identity=36.4522417153996, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24583747, Length=516, Percent_Identity=37.7906976744186, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24583749, Length=516, Percent_Identity=37.7906976744186, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24586597, Length=524, Percent_Identity=37.0229007633588, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24586599, Length=502, Percent_Identity=34.8605577689243, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24586589, Length=500, Percent_Identity=37.8, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI45549022, Length=522, Percent_Identity=34.2911877394636, Blast_Score=291, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24586591, Length=519, Percent_Identity=36.0308285163777, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI221330053, Length=519, Percent_Identity=34.1040462427746, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI281360393, Length=456, Percent_Identity=33.7719298245614, Blast_Score=228, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 62360; Mature: 62229

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPHAPVHKPQAQSDWWKGAVIYQVYPRSFQDTTGDGYGDLAGVTKRLPYIASLGVDAI
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEE
WLSPFFTSPMADMGYDVSDYCNVDPMFGTLADFDALMAEAHRLGLKVIIDQVISHTSDKH
EECHHHCCCHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PWFVDSRASRINSKADWYVWANPKPDGTAPTNWLSVFGGPAWEWDGVRKQYYMHSFLASQ
CEEECCHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
PDLNFHNPEVQDAVLETVRFWLDRGVDGFRLDTVNHYFHDKLLRDNPPLVDDESFGLDAS
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DVNPYGMQDHLYDKTRPENVAFLKRFRALLDDYEGRATVGEVGDGARSLKTVAAYTSGND
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHEEEECCCC
KLNMCYTFDLLGPDFSAKHLRGSVETFGKVVTDGWVCWAFSNHDVVRHLSRFSEGPEEQT
EEEEEEEEEECCCCCCHHHHCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCCHHHH
RVAKLAICVLASLRGSICLYQGEELGLTEAELAFEDLRDPYGIRFWPAFKGRDGCRTPMV
HHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCE
WETGKPNAGFSTAEKPWLPVPYVHAMQAVDAQERKPDSVLNHYRAVLSFRKTHGALRDGD
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
MHFIKTNLDVLAFTRQRGDEKLLFVFNLTREPVEFPVPKAMSVTDILQMPGFAPLYDAGI
EEEEECCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCE
VKLEGLDVFCGIVA
EEECCCEEEEEECC
>Mature Secondary Structure 
TLPHAPVHKPQAQSDWWKGAVIYQVYPRSFQDTTGDGYGDLAGVTKRLPYIASLGVDAI
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEE
WLSPFFTSPMADMGYDVSDYCNVDPMFGTLADFDALMAEAHRLGLKVIIDQVISHTSDKH
EECHHHCCCHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PWFVDSRASRINSKADWYVWANPKPDGTAPTNWLSVFGGPAWEWDGVRKQYYMHSFLASQ
CEEECCHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
PDLNFHNPEVQDAVLETVRFWLDRGVDGFRLDTVNHYFHDKLLRDNPPLVDDESFGLDAS
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DVNPYGMQDHLYDKTRPENVAFLKRFRALLDDYEGRATVGEVGDGARSLKTVAAYTSGND
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHEEEECCCC
KLNMCYTFDLLGPDFSAKHLRGSVETFGKVVTDGWVCWAFSNHDVVRHLSRFSEGPEEQT
EEEEEEEEEECCCCCCHHHHCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCCHHHH
RVAKLAICVLASLRGSICLYQGEELGLTEAELAFEDLRDPYGIRFWPAFKGRDGCRTPMV
HHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCE
WETGKPNAGFSTAEKPWLPVPYVHAMQAVDAQERKPDSVLNHYRAVLSFRKTHGALRDGD
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
MHFIKTNLDVLAFTRQRGDEKLLFVFNLTREPVEFPVPKAMSVTDILQMPGFAPLYDAGI
EEEEECCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCE
VKLEGLDVFCGIVA
EEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]