Click here to switch to the map view.

The map label for this gene is mcpA [C]

Identifier: 159185107

GI number: 159185107

Start: 2191182

End: 2193446

Strand: Direct

Name: mcpA [C]

Synonym: Atu2223

Alternate gene names: 159185107

Gene position: 2191182-2193446 (Clockwise)

Preceding gene: 159185103

Following gene: 15889503

Centisome position: 77.11

GC content: 61.28

Gene sequence:

>2265_bases
ATGCCGGGTGTAAATCCGACTGCTGTCAAAGCTAAATCATTGTCAATCAAGGCCAAATTCGCGGCGCTCGTCACGGGCGC
GACGCTGGTCTCCTGCCTGTCCGTGGGGTTGTTGTCCTACGAGATGGGCAAGTCGGGCCTTATCGACGCCAGCGAAATCA
GGCTCGAAACGGTTGCAAGCAACCAATCCAAGCAGCTTGACGCCTATACTTTGCGTGTCGAACAAAGCATCACCGAACTG
TCGCAGAATGCCGCAATCGCCCAGGCGCTGGAAACGATGACCACTGTCGTGCCGACGGAAAAGGATGCCATCATCCAGGC
TTTCCGCCGTGAAGGCGTCTCCGAGGAGGAGCGCGCTTCCTTCAACGGCGAAGGGTTGCGACTGCTTTATGCCATTCGCC
ACGCGACCATCAACGCCGCCATCGCCAGCGTCTGGCGCAATACCCGCGTCAGCGATATCTATGTCATCGACAAGAACGGC
CTCATTATCTATTCCGTGACCAAGGGAAAGAACTTCCTGACCAACGTGACGGAACCGCAGAACGCCGCGATCAAGGACCT
GTTCCAGCGCATCGAAGCCGGCAAGGATGGTGTCGTCAGCACCACCGGTTTCAGTGGCGGCGATAGTGATTCGGCCATGA
TCGGCATGCCGCTCGCGGTCTCAAACTGGGGCCAGCTGCAGCGCAAGGGCGCCGTCATCATGCGCGTTGCCGCCGACCGT
ATCGGCGCAGTCGTCACACCCGAAGAAACCGGCAAGACCATTGATGACGCCGTTCTTCTGAGCGCGGAGGGCAAACGCCG
CGCCGGCGTGCTCTCGGGCGGCGCGGATGCTGCCATTTCCGAAAATCTCGCGGCCCTTTCGGGCGCAAGCGACCCTGGAA
TGGTGCTGGCACAGACGCCTGCCGGCAACATCTTCTATGCCTATCGCCCGGTCACCGTGTTTGGCCAGAAGCATCTTCTG
GCCATCGGCCAGCAGGAGAGCAAGGTGCTGGCCGCCGCCAACGATCTTGCCTTCTGGGCGGCCGTTGCGACCCTTGCCGT
TCTTGCGATCATGACGCTGATCGGCATCTTTGTATCCGCAAGCCTCACCAAGCCGTTGACCGGTCTTGCCGGATTGATGG
AGCGCCTCAACGGCGGTGACAACAATATCGAGATCAAGGCGGTTTCCCGCGGCGATGAGATCGGCACCATGGCGCGCGCG
CTGGAATCCTTCCGCCAGGGCATTCTGGACAAGCAGCGCATGGAAGCCGAATCCCATCGCAAGGGCGAGGAACTGGATGA
GGAACGCGCCCAGCGTGAAATGGAAAAGGCCAGAAGCGCCAAGGAACTGGAAGAGGCCGTCGATGCACTCGCGACCGGTC
TTGCCAATCTGGCCGCCGGCAGACTTGATCGTCGCATCGAAAAATCCTTCGTGCCGTCGCTCGATCATCTGCGCGTCGAC
TTCAACAACTCCATGGCCGGGCTGGAAGCGACGATCTCCAATATCGGCGAAAGCGCCAATGCCATCCGCTCCGGCTCCGG
CGAACTGAAGAGCGCATCGGAAGACCTGTCGCGGCGCACCGAACGTCAGGCCGCAGCCCTTGAGGAAGCGGCTGCAGCGC
TCGGAGAGATGACGCAGGCCGTCGATCTCTCCCTGTCGCGCTGCAATGTTGCTGTCGAGGCGACGGCAGGCACGATGCAG
GACGCCCACAAGTCTACGGCTGTGGTGAAAGAAGCGATCGTCGCCATGGAACGCATCGAGACCTCTTCGTCCAAGATCCG
CCAGATCATCGACGTCATCGACCAGATCGCCTTCCAGACCAACCTGCTGGCCCTGAATGCCGGCGTGGAAGCCGCACGCG
CCGGTGAAGCCGGAAAGGGCTTTGCCGTTGTGGCGCAGGAAGTCCGCGAACTGGCCCAGAAATCGGCCGCCGCCGCGCGT
GACATCACGACGCTGATCGCCACCTCGGCGGGCGATGTGGAAAGCGGTGTCGCGCTGGTGCTGAAGACTGGCGAAAGCCT
GGAGCAGATCCAGAAACGCATCCAGTCGGTCAACGACCAGATCGGCGAAATCGCCACCGCATCGCGCGAACAGTCCGGCC
GCCTCAGCGAAATCAACGCCTCCGTCAACGAACTCGACCATGTCACGCAGCAGAATGCGGCGATGGTGGAACAAACCACG
GCTTCGGCCTTCTCATTGGCAAGTGAGGCGGATGGCCTGACCGAACAGGTCGGGCAGTTCTCAGTGGGCGAGACCCGGCA
CGCGGACCAGCGTTACGCGGCATAA

Upstream 100 bases:

>100_bases
CGGCATGCGGGAAATAATCGTACAATTTGCAGCCCTTTAACGCGACCGTAAGCAATTTTTGCCACCGTGCGACAACGTTT
TTTTGGGGGGAGGAAACAGG

Downstream 100 bases:

>100_bases
GCCACAAGGAAAAAAGGCCGGAGACAAAACCTCCGGCCTTTTATTTTGCTTAAAACTCCGATCCGGGCTCCCAGGGGCCG
AAGCCCCTGGGAACACGCCG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MPGVNPTAVKAKSLSIKAKFAALVTGATLVSCLSVGLLSYEMGKSGLIDASEIRLETVASNQSKQLDAYTLRVEQSITEL
SQNAAIAQALETMTTVVPTEKDAIIQAFRREGVSEEERASFNGEGLRLLYAIRHATINAAIASVWRNTRVSDIYVIDKNG
LIIYSVTKGKNFLTNVTEPQNAAIKDLFQRIEAGKDGVVSTTGFSGGDSDSAMIGMPLAVSNWGQLQRKGAVIMRVAADR
IGAVVTPEETGKTIDDAVLLSAEGKRRAGVLSGGADAAISENLAALSGASDPGMVLAQTPAGNIFYAYRPVTVFGQKHLL
AIGQQESKVLAAANDLAFWAAVATLAVLAIMTLIGIFVSASLTKPLTGLAGLMERLNGGDNNIEIKAVSRGDEIGTMARA
LESFRQGILDKQRMEAESHRKGEELDEERAQREMEKARSAKELEEAVDALATGLANLAAGRLDRRIEKSFVPSLDHLRVD
FNNSMAGLEATISNIGESANAIRSGSGELKSASEDLSRRTERQAAALEEAAAALGEMTQAVDLSLSRCNVAVEATAGTMQ
DAHKSTAVVKEAIVAMERIETSSSKIRQIIDVIDQIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQKSAAAAR
DITTLIATSAGDVESGVALVLKTGESLEQIQKRIQSVNDQIGEIATASREQSGRLSEINASVNELDHVTQQNAAMVEQTT
ASAFSLASEADGLTEQVGQFSVGETRHADQRYAA

Sequences:

>Translated_754_residues
MPGVNPTAVKAKSLSIKAKFAALVTGATLVSCLSVGLLSYEMGKSGLIDASEIRLETVASNQSKQLDAYTLRVEQSITEL
SQNAAIAQALETMTTVVPTEKDAIIQAFRREGVSEEERASFNGEGLRLLYAIRHATINAAIASVWRNTRVSDIYVIDKNG
LIIYSVTKGKNFLTNVTEPQNAAIKDLFQRIEAGKDGVVSTTGFSGGDSDSAMIGMPLAVSNWGQLQRKGAVIMRVAADR
IGAVVTPEETGKTIDDAVLLSAEGKRRAGVLSGGADAAISENLAALSGASDPGMVLAQTPAGNIFYAYRPVTVFGQKHLL
AIGQQESKVLAAANDLAFWAAVATLAVLAIMTLIGIFVSASLTKPLTGLAGLMERLNGGDNNIEIKAVSRGDEIGTMARA
LESFRQGILDKQRMEAESHRKGEELDEERAQREMEKARSAKELEEAVDALATGLANLAAGRLDRRIEKSFVPSLDHLRVD
FNNSMAGLEATISNIGESANAIRSGSGELKSASEDLSRRTERQAAALEEAAAALGEMTQAVDLSLSRCNVAVEATAGTMQ
DAHKSTAVVKEAIVAMERIETSSSKIRQIIDVIDQIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQKSAAAAR
DITTLIATSAGDVESGVALVLKTGESLEQIQKRIQSVNDQIGEIATASREQSGRLSEINASVNELDHVTQQNAAMVEQTT
ASAFSLASEADGLTEQVGQFSVGETRHADQRYAA
>Mature_753_residues
PGVNPTAVKAKSLSIKAKFAALVTGATLVSCLSVGLLSYEMGKSGLIDASEIRLETVASNQSKQLDAYTLRVEQSITELS
QNAAIAQALETMTTVVPTEKDAIIQAFRREGVSEEERASFNGEGLRLLYAIRHATINAAIASVWRNTRVSDIYVIDKNGL
IIYSVTKGKNFLTNVTEPQNAAIKDLFQRIEAGKDGVVSTTGFSGGDSDSAMIGMPLAVSNWGQLQRKGAVIMRVAADRI
GAVVTPEETGKTIDDAVLLSAEGKRRAGVLSGGADAAISENLAALSGASDPGMVLAQTPAGNIFYAYRPVTVFGQKHLLA
IGQQESKVLAAANDLAFWAAVATLAVLAIMTLIGIFVSASLTKPLTGLAGLMERLNGGDNNIEIKAVSRGDEIGTMARAL
ESFRQGILDKQRMEAESHRKGEELDEERAQREMEKARSAKELEEAVDALATGLANLAAGRLDRRIEKSFVPSLDHLRVDF
NNSMAGLEATISNIGESANAIRSGSGELKSASEDLSRRTERQAAALEEAAAALGEMTQAVDLSLSRCNVAVEATAGTMQD
AHKSTAVVKEAIVAMERIETSSSKIRQIIDVIDQIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQKSAAAARD
ITTLIATSAGDVESGVALVLKTGESLEQIQKRIQSVNDQIGEIATASREQSGRLSEINASVNELDHVTQQNAAMVEQTTA
SAFSLASEADGLTEQVGQFSVGETRHADQRYAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=296, Percent_Identity=43.5810810810811, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI1788195, Length=253, Percent_Identity=44.6640316205534, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1788194, Length=295, Percent_Identity=39.3220338983051, Blast_Score=172, Evalue=9e-44,
Organism=Escherichia coli, GI1787690, Length=285, Percent_Identity=40.7017543859649, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789453, Length=232, Percent_Identity=37.5, Blast_Score=140, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 79733; Mature: 79602

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGVNPTAVKAKSLSIKAKFAALVTGATLVSCLSVGLLSYEMGKSGLIDASEIRLETVAS
CCCCCCCCEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NQSKQLDAYTLRVEQSITELSQNAAIAQALETMTTVVPTEKDAIIQAFRREGVSEEERAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCC
FNGEGLRLLYAIRHATINAAIASVWRNTRVSDIYVIDKNGLIIYSVTKGKNFLTNVTEPQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCHHCCCCCCC
NAAIKDLFQRIEAGKDGVVSTTGFSGGDSDSAMIGMPLAVSNWGQLQRKGAVIMRVAADR
HHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCEECCCHHHHHHCCHHEEEEHHHH
IGAVVTPEETGKTIDDAVLLSAEGKRRAGVLSGGADAAISENLAALSGASDPGMVLAQTP
HCEEECCHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECC
AGNIFYAYRPVTVFGQKHLLAIGQQESKVLAAANDLAFWAAVATLAVLAIMTLIGIFVSA
CCCEEEEEECEEEECCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLTKPLTGLAGLMERLNGGDNNIEIKAVSRGDEIGTMARALESFRQGILDKQRMEAESHR
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGEELDEERAQREMEKARSAKELEEAVDALATGLANLAAGRLDRRIEKSFVPSLDHLRVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEE
FNNSMAGLEATISNIGESANAIRSGSGELKSASEDLSRRTERQAAALEEAAAALGEMTQA
CCCCHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDLSLSRCNVAVEATAGTMQDAHKSTAVVKEAIVAMERIETSSSKIRQIIDVIDQIAFQT
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NLLALNAGVEAARAGEAGKGFAVVAQEVRELAQKSAAAARDITTLIATSAGDVESGVALV
CEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LKTGESLEQIQKRIQSVNDQIGEIATASREQSGRLSEINASVNELDHVTQQNAAMVEQTT
EECCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAFSLASEADGLTEQVGQFSVGETRHADQRYAA
HHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
PGVNPTAVKAKSLSIKAKFAALVTGATLVSCLSVGLLSYEMGKSGLIDASEIRLETVAS
CCCCCCCEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NQSKQLDAYTLRVEQSITELSQNAAIAQALETMTTVVPTEKDAIIQAFRREGVSEEERAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCC
FNGEGLRLLYAIRHATINAAIASVWRNTRVSDIYVIDKNGLIIYSVTKGKNFLTNVTEPQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCHHCCCCCCC
NAAIKDLFQRIEAGKDGVVSTTGFSGGDSDSAMIGMPLAVSNWGQLQRKGAVIMRVAADR
HHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCEECCCHHHHHHCCHHEEEEHHHH
IGAVVTPEETGKTIDDAVLLSAEGKRRAGVLSGGADAAISENLAALSGASDPGMVLAQTP
HCEEECCHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECC
AGNIFYAYRPVTVFGQKHLLAIGQQESKVLAAANDLAFWAAVATLAVLAIMTLIGIFVSA
CCCEEEEEECEEEECCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLTKPLTGLAGLMERLNGGDNNIEIKAVSRGDEIGTMARALESFRQGILDKQRMEAESHR
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGEELDEERAQREMEKARSAKELEEAVDALATGLANLAAGRLDRRIEKSFVPSLDHLRVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEE
FNNSMAGLEATISNIGESANAIRSGSGELKSASEDLSRRTERQAAALEEAAAALGEMTQA
CCCCHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDLSLSRCNVAVEATAGTMQDAHKSTAVVKEAIVAMERIETSSSKIRQIIDVIDQIAFQT
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NLLALNAGVEAARAGEAGKGFAVVAQEVRELAQKSAAAARDITTLIATSAGDVESGVALV
CEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LKTGESLEQIQKRIQSVNDQIGEIATASREQSGRLSEINASVNELDHVTQQNAAMVEQTT
EECCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAFSLASEADGLTEQVGQFSVGETRHADQRYAA
HHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]