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The map label for this gene is mcpA [H]

Identifier: 159185086

GI number: 159185086

Start: 2145191

End: 2147281

Strand: Direct

Name: mcpA [H]

Synonym: Atu2173

Alternate gene names: 159185086

Gene position: 2145191-2147281 (Clockwise)

Preceding gene: 159185085

Following gene: 159185087

Centisome position: 75.49

GC content: 60.5

Gene sequence:

>2091_bases
TTGCCAAAGAAAACCAATCTTATGACGCGCATTCTGGTTGCAGCGTCATCTCTTGTCGTTGCAGCCTTTGCAGGCTTTTC
CTATTACATCGACAGCCTCCAGCATCGGGTTACTACCGAAGCAGTCGCGGAAAACATTGATTCTTCCGGCAAGCAGGCTG
CGCAAAGCATCGCCAACTGGCTGAACGGTCGCATCATGCTGACACAAACGGTGGCGGCAACCCTGGCCAAGCTTCCGGAT
GACGAGGCAAAGCTGCGTTTTCTGGAAAATGACGTGCTGACGGCACAGTTCATGTCGACCTATTTCGGCAATGCCGAGAC
AGGCACCTTCACCACCTTCCCGAAGACACCGCTGCCGGAAGGTTACGATCCGCGCAAGCGTCCGTGGTATCTGGATGCGG
TGAAAGCCGGCAAGACGGTTCTGACGGAACCCTATAATGACGCCTCGACCGGAGGCCTTATCATCACCGCCGCTATTCCC
GTTTCCATCGATGGCAAGCTTGCCGGTGTGACAGGCAGCGATTTCTCGCTGGATTCGCTGGTGAAGATGATCAAGTCGGT
GGATGCCGGCACGGATGGCTACGCGTTCCTCGTCAGCAAGGACGGCAAAATCCTCATTCATCCGGATCCAAAATTCGTCG
ACAAGCCGCTGGCCGATCTCTTCAAGGTCGATACGCCGGCGATTTCCTCCGCGATTTCCCAGACCGAAATCGACGGCAAG
GGCAAGATCACCAGCTTCATCCCGGTTGCGGGCCTGCCTTCGGTCGACTGGTATCTCGGTTTCGTCGTGGATTCCGACGT
CGCCTACAGCGCGATCGGCCAGTTCCGCCTGGCGGCGACCATCGCAACGGTTCTCGCCGCCGCGATCATGATTGGCCTGC
TGGCGACCGTGCTGTCCCGCTTCATCGTCCGCCCTGTCACGCAGATGACCTCTGCCATGGAAGGTCTTGCCGCCGGTAAT
CTCGATGTCGGCATTCCCGGCCAGGAACGCACCGACCAGATCGGCTCCATGGCTGCAGCCGTCGCCGTGTTCCGCTCGAA
CGCAATGGAGCGCCTACGCCTTGAGGGCGATGCCGAACAGAACCGCACGCTTTCCGAACAGGAGCGCAACGAGCGCGAAA
GAACCGCAGCAAAAGACGCGGCGGATATCCAGTTCGCGGTCGACTCGCTTGCCAAGGGTCTGGCGCATCTTTCCGATGGC
GATCTCAACTATCGCATCGACACGCCTTTCGTGACCCGCATCGATCGCCTTCGTAACGATTTCAACAATTCCGTTGCGAA
GCTGAATGCGGCGCTCAGCACGGTCGGCCAGAATGCGCTCGCCATCGACGCCGGAGCCGGCGAAATCCGCCAGTCCGCCG
ACGATCTGGCACGCCGCACCGAGCAGCAGGCGGCCTCCGTCGAGGAAACCGCCGCAGCACTCGAAGAGATCACCACGACG
GTGAAGGATTCCGCCCGCCGTGCCGAAGAAGTCGGCCGTCTGGTCGATCGCGCCCGCGGCAATGCCGAACAGTCCGGCGT
CATTGTGGAAGATGCCGTGCGTGCCATGGAAGGCATCGAAAAATCCTCGTCGGAGATCAGCAACATCATCGGCGTAATCG
ACGAGATCGCCTTCCAGACCAACCTCCTGGCGCTGAATGCCGGTGTCGAAGCCGCCCGCGCCGGTGAGGCCGGCAAGGGT
TTTGCCGTCGTCGCACAGGAAGTGCGCGAACTCGCCCAGCGCTCCGCCAATGCCGCCAAAGCGATCAAGACATTGATCAA
CGCCTCGACATCGCAGGTGCAGTCCGGCGTCGAACTCGTCGGCAATGCCGGCAAGGCGCTGGAAACCATCGTTCGCGAAG
TGCAGGAGATCAACCGCCACATCGATGCCATCGTGACATCGTCGCGCGAACAGTCGACCGGACTTCAGGAAATCAACACC
GCCATCAACACCATCGATCAGGGCACGCAGCAGAATGCCGCCATGGTCGAGGAACAGACGGCGGCAAGCCACGGCCTTGC
CTCGGAAGCGGCGGCGCTCAACGAGTTGCTTGCACAGTTCCAGCTCGCCGCCGCCACGCGGCGGCAGGCGGAATATGGTC
GGGCTGCTTAA

Upstream 100 bases:

>100_bases
TAAGCTGCATGACGCAGATTATTCCCGCCTTTGAGGCATGTTTCCCCCATCAATGTTAAAGATGACCTCGACGGTACATC
CGGCTTCAAGGATCCGTAGC

Downstream 100 bases:

>100_bases
CGGGATAAACAATTTGTTGGATTCGCTACAGCAGGCAGACATCCGTCAAACATTACCCCCCTCTTGGCGTCATCCTCGGG
CTTGTCCCGAGGATCTAACC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MPKKTNLMTRILVAASSLVVAAFAGFSYYIDSLQHRVTTEAVAENIDSSGKQAAQSIANWLNGRIMLTQTVAATLAKLPD
DEAKLRFLENDVLTAQFMSTYFGNAETGTFTTFPKTPLPEGYDPRKRPWYLDAVKAGKTVLTEPYNDASTGGLIITAAIP
VSIDGKLAGVTGSDFSLDSLVKMIKSVDAGTDGYAFLVSKDGKILIHPDPKFVDKPLADLFKVDTPAISSAISQTEIDGK
GKITSFIPVAGLPSVDWYLGFVVDSDVAYSAIGQFRLAATIATVLAAAIMIGLLATVLSRFIVRPVTQMTSAMEGLAAGN
LDVGIPGQERTDQIGSMAAAVAVFRSNAMERLRLEGDAEQNRTLSEQERNERERTAAKDAADIQFAVDSLAKGLAHLSDG
DLNYRIDTPFVTRIDRLRNDFNNSVAKLNAALSTVGQNALAIDAGAGEIRQSADDLARRTEQQAASVEETAAALEEITTT
VKDSARRAEEVGRLVDRARGNAEQSGVIVEDAVRAMEGIEKSSSEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKG
FAVVAQEVRELAQRSANAAKAIKTLINASTSQVQSGVELVGNAGKALETIVREVQEINRHIDAIVTSSREQSTGLQEINT
AINTIDQGTQQNAAMVEEQTAASHGLASEAAALNELLAQFQLAAATRRQAEYGRAA

Sequences:

>Translated_696_residues
MPKKTNLMTRILVAASSLVVAAFAGFSYYIDSLQHRVTTEAVAENIDSSGKQAAQSIANWLNGRIMLTQTVAATLAKLPD
DEAKLRFLENDVLTAQFMSTYFGNAETGTFTTFPKTPLPEGYDPRKRPWYLDAVKAGKTVLTEPYNDASTGGLIITAAIP
VSIDGKLAGVTGSDFSLDSLVKMIKSVDAGTDGYAFLVSKDGKILIHPDPKFVDKPLADLFKVDTPAISSAISQTEIDGK
GKITSFIPVAGLPSVDWYLGFVVDSDVAYSAIGQFRLAATIATVLAAAIMIGLLATVLSRFIVRPVTQMTSAMEGLAAGN
LDVGIPGQERTDQIGSMAAAVAVFRSNAMERLRLEGDAEQNRTLSEQERNERERTAAKDAADIQFAVDSLAKGLAHLSDG
DLNYRIDTPFVTRIDRLRNDFNNSVAKLNAALSTVGQNALAIDAGAGEIRQSADDLARRTEQQAASVEETAAALEEITTT
VKDSARRAEEVGRLVDRARGNAEQSGVIVEDAVRAMEGIEKSSSEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKG
FAVVAQEVRELAQRSANAAKAIKTLINASTSQVQSGVELVGNAGKALETIVREVQEINRHIDAIVTSSREQSTGLQEINT
AINTIDQGTQQNAAMVEEQTAASHGLASEAAALNELLAQFQLAAATRRQAEYGRAA
>Mature_695_residues
PKKTNLMTRILVAASSLVVAAFAGFSYYIDSLQHRVTTEAVAENIDSSGKQAAQSIANWLNGRIMLTQTVAATLAKLPDD
EAKLRFLENDVLTAQFMSTYFGNAETGTFTTFPKTPLPEGYDPRKRPWYLDAVKAGKTVLTEPYNDASTGGLIITAAIPV
SIDGKLAGVTGSDFSLDSLVKMIKSVDAGTDGYAFLVSKDGKILIHPDPKFVDKPLADLFKVDTPAISSAISQTEIDGKG
KITSFIPVAGLPSVDWYLGFVVDSDVAYSAIGQFRLAATIATVLAAAIMIGLLATVLSRFIVRPVTQMTSAMEGLAAGNL
DVGIPGQERTDQIGSMAAAVAVFRSNAMERLRLEGDAEQNRTLSEQERNERERTAAKDAADIQFAVDSLAKGLAHLSDGD
LNYRIDTPFVTRIDRLRNDFNNSVAKLNAALSTVGQNALAIDAGAGEIRQSADDLARRTEQQAASVEETAAALEEITTTV
KDSARRAEEVGRLVDRARGNAEQSGVIVEDAVRAMEGIEKSSSEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGF
AVVAQEVRELAQRSANAAKAIKTLINASTSQVQSGVELVGNAGKALETIVREVQEINRHIDAIVTSSREQSTGLQEINTA
INTIDQGTQQNAAMVEEQTAASHGLASEAAALNELLAQFQLAAATRRQAEYGRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=292, Percent_Identity=43.1506849315069, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=42.809364548495, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=46.2745098039216, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI2367378, Length=301, Percent_Identity=43.5215946843854, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789453, Length=231, Percent_Identity=40.6926406926407, Blast_Score=156, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74012; Mature: 73881

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKTNLMTRILVAASSLVVAAFAGFSYYIDSLQHRVTTEAVAENIDSSGKQAAQSIANW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LNGRIMLTQTVAATLAKLPDDEAKLRFLENDVLTAQFMSTYFGNAETGTFTTFPKTPLPE
HCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
GYDPRKRPWYLDAVKAGKTVLTEPYNDASTGGLIITAAIPVSIDGKLAGVTGSDFSLDSL
CCCCCCCCEEHHHHHCCCEEEECCCCCCCCCCEEEEEEECEEECCEEECCCCCCCCHHHH
VKMIKSVDAGTDGYAFLVSKDGKILIHPDPKFVDKPLADLFKVDTPAISSAISQTEIDGK
HHHHHHCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
GKITSFIPVAGLPSVDWYLGFVVDSDVAYSAIGQFRLAATIATVLAAAIMIGLLATVLSR
CCEEEEECCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRPVTQMTSAMEGLAAGNLDVGIPGQERTDQIGSMAAAVAVFRSNAMERLRLEGDAEQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NRTLSEQERNERERTAAKDAADIQFAVDSLAKGLAHLSDGDLNYRIDTPFVTRIDRLRND
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHH
FNNSVAKLNAALSTVGQNALAIDAGAGEIRQSADDLARRTEQQAASVEETAAALEEITTT
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKDSARRAEEVGRLVDRARGNAEQSGVIVEDAVRAMEGIEKSSSEISNIIGVIDEIAFQT
HHHHHHHHHHHHHHHHHHCCCCHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKAIKTLINASTSQVQSGVELV
HHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
GNAGKALETIVREVQEINRHIDAIVTSSREQSTGLQEINTAINTIDQGTQQNAAMVEEQT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
AASHGLASEAAALNELLAQFQLAAATRRQAEYGRAA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKKTNLMTRILVAASSLVVAAFAGFSYYIDSLQHRVTTEAVAENIDSSGKQAAQSIANW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LNGRIMLTQTVAATLAKLPDDEAKLRFLENDVLTAQFMSTYFGNAETGTFTTFPKTPLPE
HCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
GYDPRKRPWYLDAVKAGKTVLTEPYNDASTGGLIITAAIPVSIDGKLAGVTGSDFSLDSL
CCCCCCCCEEHHHHHCCCEEEECCCCCCCCCCEEEEEEECEEECCEEECCCCCCCCHHHH
VKMIKSVDAGTDGYAFLVSKDGKILIHPDPKFVDKPLADLFKVDTPAISSAISQTEIDGK
HHHHHHCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
GKITSFIPVAGLPSVDWYLGFVVDSDVAYSAIGQFRLAATIATVLAAAIMIGLLATVLSR
CCEEEEECCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRPVTQMTSAMEGLAAGNLDVGIPGQERTDQIGSMAAAVAVFRSNAMERLRLEGDAEQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NRTLSEQERNERERTAAKDAADIQFAVDSLAKGLAHLSDGDLNYRIDTPFVTRIDRLRND
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHH
FNNSVAKLNAALSTVGQNALAIDAGAGEIRQSADDLARRTEQQAASVEETAAALEEITTT
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKDSARRAEEVGRLVDRARGNAEQSGVIVEDAVRAMEGIEKSSSEISNIIGVIDEIAFQT
HHHHHHHHHHHHHHHHHHCCCCHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKAIKTLINASTSQVQSGVELV
HHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
GNAGKALETIVREVQEINRHIDAIVTSSREQSTGLQEINTAINTIDQGTQQNAAMVEEQT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
AASHGLASEAAALNELLAQFQLAAATRRQAEYGRAA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]