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The map label for this gene is caiB [H]

Identifier: 159185061

GI number: 159185061

Start: 2092326

End: 2093528

Strand: Direct

Name: caiB [H]

Synonym: Atu2127

Alternate gene names: 159185061

Gene position: 2092326-2093528 (Clockwise)

Preceding gene: 159185060

Following gene: 159185062

Centisome position: 73.63

GC content: 60.93

Gene sequence:

>1203_bases
ATGACCGACATGCCGAACAGGAAACCGCCGCTCTCAGGCATCCGCGTCATTGAGCTGGCGCGTGTTCTGGCTGGTCCCTG
GGCGGGGCAGATGCTGGCCGATATGGGCGCTGACGTCATCAAGGTCGAAAACCCCGAAGGTGGCGACGATACCCGGGCAT
GGGGGCCACCCTTCGTCGAAAGCGCCGATGGCGAAAACCTGTCTGCCGCCTATTACCACGCCACCAATCGTGGCAAACGC
TCCATCGTCGCCGATCTGAAAACGCCCGAAGGCTGTGCGCTGGTGCGCCGGCTGGTCCGCACTGCCGATGTCGTTATCGA
AAACTTCAAGCGCGACGGGCTTGCCAAATATGGCCTCGATTACGAGAGCCTGAGGGTGCTCAATCCGAAGCTGATCTATT
GCTCCATCACCGGCTTCGGCCAGACCGGACCTTATGCCGATTTTGCCGGATACGACTATATCGTGCAGGGCATGTCCGGT
TTCATGTCGATTACGGGCGAACCGGACGGCCAGCCGATGAAGGCCGGCGTGGCGGTCGCCGATATCTTCACCGGCATCTA
TTCCGTGTCAGCCATTCAGGCCGCCCTCATCCACGCCATGCGATCAGGCGAGGGGCAGCACATCGACATGGCGCTTCTCG
ATGTGCAATCGGCCGTGCTCGCCAACCAGAACATGAATTACCTGATCTCCGGCCGCCCGCCCATCCGGCTCGGTAACGCC
CACCCGAATATTTCCCCCTATGAGGTAGTGCCGACGGCCGATGGTTTCCTGATCCTCGCGGTCGGCAATGACGGCCAGTT
CCGCCGCCTCTGCAACATTCTCGGCATTGGCGCGATTGCCGATGACGAACGTTATGCGACAAACAAGGCCCGCGTGGCGC
ATAAGGTCGAAGTGCGGCAGATCATTTCCACCGAAACGCTGAAATGGAACAAGCGCGATCTTCTGACTGCTTGCGAAACG
AACGCCGTGCCGGCCGGGCCGATCAACTCCATCGAGGAAATGTTCGCCGATCCGCAGGTTCAGGCACGTGGCCTGCGCGT
CGATCTGGAGGCGGAAGACGGCACCGTCATCCCCGGTGTGCGGACACCGATTATCATGTCACAGACGCCGCTGCGTTATG
AGCGCCCGAGCCCGAAGCTCGGCGAACATCAGGCGCAGGTGCTGGCCGAACTGGAAACTATCGAAAGGACCGCGACGCCA
TGA

Upstream 100 bases:

>100_bases
GGCGTCTTTGCCGAAACGGAATAAGTCCATGAGATAAAATCACATGCGGCGCGGCAAGCAGCGGTCTATAAACCGGCAAG
CAGAAAATCCCGGGGGACAG

Downstream 100 bases:

>100_bases
AGGCAGGAATGAAAAGAACTGGTGGCCAACTGATCGTCGAAGCGCTGAAGGCCAATGGCGTCTCGCGCGTTTCCTGCGTT
CCGGGCGAAAGCTACCTGGC

Product: L-carnitine dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTDMPNRKPPLSGIRVIELARVLAGPWAGQMLADMGADVIKVENPEGGDDTRAWGPPFVESADGENLSAAYYHATNRGKR
SIVADLKTPEGCALVRRLVRTADVVIENFKRDGLAKYGLDYESLRVLNPKLIYCSITGFGQTGPYADFAGYDYIVQGMSG
FMSITGEPDGQPMKAGVAVADIFTGIYSVSAIQAALIHAMRSGEGQHIDMALLDVQSAVLANQNMNYLISGRPPIRLGNA
HPNISPYEVVPTADGFLILAVGNDGQFRRLCNILGIGAIADDERYATNKARVAHKVEVRQIISTETLKWNKRDLLTACET
NAVPAGPINSIEEMFADPQVQARGLRVDLEAEDGTVIPGVRTPIIMSQTPLRYERPSPKLGEHQAQVLAELETIERTATP

Sequences:

>Translated_400_residues
MTDMPNRKPPLSGIRVIELARVLAGPWAGQMLADMGADVIKVENPEGGDDTRAWGPPFVESADGENLSAAYYHATNRGKR
SIVADLKTPEGCALVRRLVRTADVVIENFKRDGLAKYGLDYESLRVLNPKLIYCSITGFGQTGPYADFAGYDYIVQGMSG
FMSITGEPDGQPMKAGVAVADIFTGIYSVSAIQAALIHAMRSGEGQHIDMALLDVQSAVLANQNMNYLISGRPPIRLGNA
HPNISPYEVVPTADGFLILAVGNDGQFRRLCNILGIGAIADDERYATNKARVAHKVEVRQIISTETLKWNKRDLLTACET
NAVPAGPINSIEEMFADPQVQARGLRVDLEAEDGTVIPGVRTPIIMSQTPLRYERPSPKLGEHQAQVLAELETIERTATP
>Mature_399_residues
TDMPNRKPPLSGIRVIELARVLAGPWAGQMLADMGADVIKVENPEGGDDTRAWGPPFVESADGENLSAAYYHATNRGKRS
IVADLKTPEGCALVRRLVRTADVVIENFKRDGLAKYGLDYESLRVLNPKLIYCSITGFGQTGPYADFAGYDYIVQGMSGF
MSITGEPDGQPMKAGVAVADIFTGIYSVSAIQAALIHAMRSGEGQHIDMALLDVQSAVLANQNMNYLISGRPPIRLGNAH
PNISPYEVVPTADGFLILAVGNDGQFRRLCNILGIGAIADDERYATNKARVAHKVEVRQIISTETLKWNKRDLLTACETN
AVPAGPINSIEEMFADPQVQARGLRVDLEAEDGTVIPGVRTPIIMSQTPLRYERPSPKLGEHQAQVLAELETIERTATP

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=399, Percent_Identity=41.1027568922306, Blast_Score=307, Evalue=1e-83,
Organism=Homo sapiens, GI300863124, Length=423, Percent_Identity=38.5342789598109, Blast_Score=295, Evalue=4e-80,
Organism=Homo sapiens, GI13376042, Length=423, Percent_Identity=36.1702127659575, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI300863126, Length=399, Percent_Identity=35.8395989974937, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI42794625, Length=386, Percent_Identity=27.720207253886, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI266456254, Length=386, Percent_Identity=27.720207253886, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI266458393, Length=308, Percent_Identity=30.8441558441558, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI266458397, Length=265, Percent_Identity=32.0754716981132, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI266458395, Length=150, Percent_Identity=38, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI42822893, Length=150, Percent_Identity=38, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI87082093, Length=388, Percent_Identity=37.3711340206186, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1788717, Length=413, Percent_Identity=29.5399515738499, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1786222, Length=395, Percent_Identity=26.0759493670886, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI115535051, Length=197, Percent_Identity=34.010152284264, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32564160, Length=207, Percent_Identity=30.9178743961353, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648431, Length=386, Percent_Identity=43.0051813471503, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24585488, Length=231, Percent_Identity=32.4675324675325, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43386; Mature: 43255

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMPNRKPPLSGIRVIELARVLAGPWAGQMLADMGADVIKVENPEGGDDTRAWGPPFVE
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCC
SADGENLSAAYYHATNRGKRSIVADLKTPEGCALVRRLVRTADVVIENFKRDGLAKYGLD
CCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
YESLRVLNPKLIYCSITGFGQTGPYADFAGYDYIVQGMSGFMSITGEPDGQPMKAGVAVA
HHHHEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHH
DIFTGIYSVSAIQAALIHAMRSGEGQHIDMALLDVQSAVLANQNMNYLISGRPPIRLGNA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCEEECCCCCEEECCC
HPNISPYEVVPTADGFLILAVGNDGQFRRLCNILGIGAIADDERYATNKARVAHKVEVRQ
CCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHH
IISTETLKWNKRDLLTACETNAVPAGPINSIEEMFADPQVQARGLRVDLEAEDGTVIPGV
HHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEECCCCEECCCC
RTPIIMSQTPLRYERPSPKLGEHQAQVLAELETIERTATP
CCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDMPNRKPPLSGIRVIELARVLAGPWAGQMLADMGADVIKVENPEGGDDTRAWGPPFVE
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCC
SADGENLSAAYYHATNRGKRSIVADLKTPEGCALVRRLVRTADVVIENFKRDGLAKYGLD
CCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
YESLRVLNPKLIYCSITGFGQTGPYADFAGYDYIVQGMSGFMSITGEPDGQPMKAGVAVA
HHHHEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHH
DIFTGIYSVSAIQAALIHAMRSGEGQHIDMALLDVQSAVLANQNMNYLISGRPPIRLGNA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCEEECCCCCEEECCC
HPNISPYEVVPTADGFLILAVGNDGQFRRLCNILGIGAIADDERYATNKARVAHKVEVRQ
CCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHH
IISTETLKWNKRDLLTACETNAVPAGPINSIEEMFADPQVQARGLRVDLEAEDGTVIPGV
HHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEECCCCEECCCC
RTPIIMSQTPLRYERPSPKLGEHQAQVLAELETIERTATP
CCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]