Click here to switch to the map view.

The map label for this gene is solA [H]

Identifier: 159185051

GI number: 159185051

Start: 2075243

End: 2076430

Strand: Reverse

Name: solA [H]

Synonym: Atu2111

Alternate gene names: 159185051

Gene position: 2076430-2075243 (Counterclockwise)

Preceding gene: 159185052

Following gene: 159185050

Centisome position: 73.07

GC content: 61.45

Gene sequence:

>1188_bases
ATGCCGGATTTCAAATATATCGTGGTCGGGGCCGGGATGATGGGAGCGGCCGCGGCGCGGCATCTTTCGGTGCAAACGGA
TGGCGTGGCGCTGATCGGGCCGGCCGAACCGGCTGATCGCAAGACACATCAGGGTGTATTTTCAAGTCATTACGACGTAG
CGCGTATCACCCGCGGTTTTGACGGCGATCCGGTCTGGGCCGAACTCGCGTTGCGTTCGATCCGGCGTTACGCCGAGATA
GAGGCGAAAAGCGGCATCCGGTTCTTCACCGAAGCGGGCTGCCTGTTCACGGGCAACGGCAAGGGGCTTGCGGGAGACTA
TGTATCGCGGGCGCTTTCCTCGGCAGATCGTCTCGGTCTTGGCGTGGAAACGCTTGGTGCTGAAGCGCTGGCAGGACGGT
TTCCGATGTTTGCGCTGCCTGCCGATCATGGCGGGAGCTTTGAGGCCCGCAATGCCGGCCACATCAATCCACGGGCGCTG
GTGAAAGCGCAATGCGCAATCGCCGAAGCGCAGGGCGGCCGGCTTGTGCGCGAGACGGCGGCGCATATTCGCGATACCTC
CCGTAGCGTCGAGGTCATGACGCGGGAAGGGGCCACCTATACGGCGGAAAAGGTCATCGTCGCGGCGGGCGGTTTCACCA
ATATGGCGGCGCTTCTGCCGTCACCGGTCGATATGGCGGCGACGGGCCGCACCATCGTGTTCTTCGAGCTGGATGAAGCA
CGGCAGGCGCTGTTCAGCGCGATGCCCTCGACGATCGTGCTGGCGGAAACCGAGGACGATATCGTCTATATCCTGCCGCC
AGTGCGATATCCCGATGGCAAGGTCTATCTGAAAATCGGTGGCGAAAGCGAAAAGGGCAGGCTTGAAACGCTGGTCCAAG
CGGTCGACTGGTTCCACTCGGACGGCACGCCCGATGAGGTGGAGTTCCTGACGAAAAAAGCCCTGTCGCTGATGCCGGCG
CTGGCCGGCTGCCCGGTCACATCAGGATCCTGCGTCGCCTCCATCACCTGCAGCGGTTATCCCTATATCGGCTATACGCA
ATCCTCCAATATTGCGGTTCTGACCGGCGGCAATTTCGTTTCCGCCAAGTCTTCGGATGAGATCGGGCGACTGGGCGCGC
AACTGCTTCTCAATGGCCAGCTGACCGAGGATGAGTTCGCCGCCGAAATGTCGCCGGTTTTTGTCTGA

Upstream 100 bases:

>100_bases
CGAGCTGAGGCCGGCATCGATCATCTGCGAAATTGCGAAAAACGATTCCGGTTCGGGTCGGCATGCTGTAGTCAGAAACA
AATCTGATACGGAGCATGAC

Downstream 100 bases:

>100_bases
CATTCTCCATGCAGGCAGCTACAAGAATGCGGGTGAACGGAACAGGTAAAGAGGGCGGCATGTCGGGACATTTCAACTAT
ATCGTCGTCGGTCGCGGCAT

Product: sarcosine oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPDFKYIVVGAGMMGAAAARHLSVQTDGVALIGPAEPADRKTHQGVFSSHYDVARITRGFDGDPVWAELALRSIRRYAEI
EAKSGIRFFTEAGCLFTGNGKGLAGDYVSRALSSADRLGLGVETLGAEALAGRFPMFALPADHGGSFEARNAGHINPRAL
VKAQCAIAEAQGGRLVRETAAHIRDTSRSVEVMTREGATYTAEKVIVAAGGFTNMAALLPSPVDMAATGRTIVFFELDEA
RQALFSAMPSTIVLAETEDDIVYILPPVRYPDGKVYLKIGGESEKGRLETLVQAVDWFHSDGTPDEVEFLTKKALSLMPA
LAGCPVTSGSCVASITCSGYPYIGYTQSSNIAVLTGGNFVSAKSSDEIGRLGAQLLLNGQLTEDEFAAEMSPVFV

Sequences:

>Translated_395_residues
MPDFKYIVVGAGMMGAAAARHLSVQTDGVALIGPAEPADRKTHQGVFSSHYDVARITRGFDGDPVWAELALRSIRRYAEI
EAKSGIRFFTEAGCLFTGNGKGLAGDYVSRALSSADRLGLGVETLGAEALAGRFPMFALPADHGGSFEARNAGHINPRAL
VKAQCAIAEAQGGRLVRETAAHIRDTSRSVEVMTREGATYTAEKVIVAAGGFTNMAALLPSPVDMAATGRTIVFFELDEA
RQALFSAMPSTIVLAETEDDIVYILPPVRYPDGKVYLKIGGESEKGRLETLVQAVDWFHSDGTPDEVEFLTKKALSLMPA
LAGCPVTSGSCVASITCSGYPYIGYTQSSNIAVLTGGNFVSAKSSDEIGRLGAQLLLNGQLTEDEFAAEMSPVFV
>Mature_394_residues
PDFKYIVVGAGMMGAAAARHLSVQTDGVALIGPAEPADRKTHQGVFSSHYDVARITRGFDGDPVWAELALRSIRRYAEIE
AKSGIRFFTEAGCLFTGNGKGLAGDYVSRALSSADRLGLGVETLGAEALAGRFPMFALPADHGGSFEARNAGHINPRALV
KAQCAIAEAQGGRLVRETAAHIRDTSRSVEVMTREGATYTAEKVIVAAGGFTNMAALLPSPVDMAATGRTIVFFELDEAR
QALFSAMPSTIVLAETEDDIVYILPPVRYPDGKVYLKIGGESEKGRLETLVQAVDWFHSDGTPDEVEFLTKKALSLMPAL
AGCPVTSGSCVASITCSGYPYIGYTQSSNIAVLTGGNFVSAKSSDEIGRLGAQLLLNGQLTEDEFAAEMSPVFV

Specific function: Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L- alanine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41854; Mature: 41723

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFKYIVVGAGMMGAAAARHLSVQTDGVALIGPAEPADRKTHQGVFSSHYDVARITRGF
CCCCEEEEEECCHHHHHHHHEEEEECCCEEEEECCCCCCCHHHCCHHHCCCCHHHHHCCC
DGDPVWAELALRSIRRYAEIEAKSGIRFFTEAGCLFTGNGKGLAGDYVSRALSSADRLGL
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHCCC
GVETLGAEALAGRFPMFALPADHGGSFEARNAGHINPRALVKAQCAIAEAQGGRLVRETA
CHHHHCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHH
AHIRDTSRSVEVMTREGATYTAEKVIVAAGGFTNMAALLPSPVDMAATGRTIVFFELDEA
HHHHCCCCCEEEEEECCCEEEEEEEEEEECCHHHHHHHCCCCCCCCCCCCEEEEEECCHH
RQALFSAMPSTIVLAETEDDIVYILPPVRYPDGKVYLKIGGESEKGRLETLVQAVDWFHS
HHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
DGTPDEVEFLTKKALSLMPALAGCPVTSGSCVASITCSGYPYIGYTQSSNIAVLTGGNFV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEECCCEE
SAKSSDEIGRLGAQLLLNGQLTEDEFAAEMSPVFV
ECCCCCHHHHHHHHEEECCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
PDFKYIVVGAGMMGAAAARHLSVQTDGVALIGPAEPADRKTHQGVFSSHYDVARITRGF
CCCEEEEEECCHHHHHHHHEEEEECCCEEEEECCCCCCCHHHCCHHHCCCCHHHHHCCC
DGDPVWAELALRSIRRYAEIEAKSGIRFFTEAGCLFTGNGKGLAGDYVSRALSSADRLGL
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHCCC
GVETLGAEALAGRFPMFALPADHGGSFEARNAGHINPRALVKAQCAIAEAQGGRLVRETA
CHHHHCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHH
AHIRDTSRSVEVMTREGATYTAEKVIVAAGGFTNMAALLPSPVDMAATGRTIVFFELDEA
HHHHCCCCCEEEEEECCCEEEEEEEEEEECCHHHHHHHCCCCCCCCCCCCEEEEEECCHH
RQALFSAMPSTIVLAETEDDIVYILPPVRYPDGKVYLKIGGESEKGRLETLVQAVDWFHS
HHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
DGTPDEVEFLTKKALSLMPALAGCPVTSGSCVASITCSGYPYIGYTQSSNIAVLTGGNFV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEECCCEE
SAKSSDEIGRLGAQLLLNGQLTEDEFAAEMSPVFV
ECCCCCHHHHHHHHEEECCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10220347; 10913293; 11087383; 10368302 [H]