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The map label for this gene is rpoC

Identifier: 159184989

GI number: 159184989

Start: 1922808

End: 1927016

Strand: Reverse

Name: rpoC

Synonym: Atu1955

Alternate gene names: 159184989

Gene position: 1927016-1922808 (Counterclockwise)

Preceding gene: 159184990

Following gene: 159184987

Centisome position: 67.81

GC content: 58.64

Gene sequence:

>4209_bases
ATGAACCAAGAGGTCATGAATCTTTTCAATCCTCAGGTGCCTGCGCAGCATTTCGATTCCATCCGGATTTCGATCGCTTC
GCCGGAAAAAATCCTGTCGTGGTCCTACGGCGAGATCAAGAAGCCGGAAACCATCAACTACCGTACGTTCAAGCCTGAGC
GTGACGGTCTTTTCTGCGCGCGCATCTTTGGGCCGATCAAGGACTATGAGTGCCTGTGCGGCAAGTACAAGCGCATGAAG
TACAAGGGCATCATCTGCGAAAAGTGCGGCGTCGAAGTGACGCTGTCGCGCGTTCGCCGTGAGCGCATGGGCCACATTGA
GCTCGCAGCGCCGGTTGCCCATATCTGGTTCCTGAAGTCGCTTCCTTCGCGTATCTCGACCTTGCTCGACATGACGCTGA
AGGATGTCGAACGCGTTCTCTATTTCGAGAACTACATCGTCACCGAGCCTGGCCTCACTTCGCTGAAGCAGAACCAGCTT
CTGTCTGAAGAAGAGTACATGATCGCCGTTGACGAGTTCGGCGAAGACCAGTTCACCGCCATGATCGGCGCTGAAGCCAT
CTATGAGATGCTGGCTTCGATGAACCTCGAAAAGATCGCCGGCGACCTGCGCGCCGAGCTTGCTGAAACGACTTCTGACC
TCAAGCAGAAGAAGTTCATGAAGCGCCTGAAGATCGTCGAGAACTTCATGGAGAGCGGCAATCGTCCGGAATGGATGATC
ATGAAGGTCGTTCCGGTCATTCCGCCGGACCTGCGTCCGCTGGTTCCGCTGGATGGCGGTCGTTTTGCGACGTCCGACCT
CAACGATCTCTATCGCCGCGTCATCAACCGTAACAACCGTCTGAAGCGCCTGATCGAGCTTCGTGCGCCTGGCATCATCA
TCCGCAATGAAAAGCGTATGTTGCAGGAATCCGTCGATGCGCTGTTCGACAACGGCCGTCGCGGCCGCGTCATCACGGGT
GCCAACAAGCGTCCGCTGAAGTCGCTCTCCGACATGCTCAAGGGCAAGCAGGGCCGTTTCCGCCAGAACCTTCTCGGCAA
GCGCGTCGACTATTCCGGCCGTTCGGTTATCGTGACCGGTCCGGAACTGAAGCTGCACCAGTGCGGCCTGCCGAAGAAGA
TGGCGCTCGAACTGTTCAAGCCGTTCATCTATGCCCGTCTCGACGCTAAGGGTTACTCCTCGACCGTCAAGCAGGCCAAG
AAGCTGGTTGAAAAGGAAAAGCCGGAGGTCTGGGATATCCTCGACGAGGTCATCCGCGAACATCCGGTTCTTCTGAACCG
CGCACCGACGCTGCACCGTCTGGGTATCCAGGCTTTCGAACCCATGCTGGTCGAAGGCAAGGCCATCCAGCTGCATCCGC
TCGTCTGCACGGCCTTCAACGCCGACTTCGACGGTGACCAGATGGCTGTTCACGTTCCGCTTTCGCTGGAAGCCCAGCTG
GAAGCGCGCGTGCTGATGATGTCGACCAACAACATCCTGCATCCGGCAAACGGCCACCCGATCATCGTTCCGTCGCAGGA
CATGGTTCTCGGCCTGTATTACCTGTCGATCATGAACCAGAACGAGCCCGGCGAAGGCATGGCTTTCTCGGATATCGGCG
AATTGCATCACGCGCTTGAAAACAAGGTCGTGACGCTGCATGCCAAGATCCGTGGCCGCTTCAAGACCGTGGATGCCGAC
GGCAAGCCGGTTTCCAAGATCCATGAAACGACGCCTGGCCGTATGCTCATCGGCGAACTTCTGCCGAAGAACGTCAACGT
GCCTTTCGACACCTGCAACCAGGAAATGACCAAGAAGAACATCTCCAAGATGATCGACACGGTCTACCGTCATTGCGGCC
AGAAAGACACGGTCATCTTCTGCGACCGGATCATGCAGCTCGGCTTCAGCCACGCCTGCCGCGCCGGCATTTCGTTCGGC
AAGGACGACATGGTCATTCCGGACAGCAAGGTGAAGATCGTCGGCGACACCGAAGCTCTCGTGAAGGAATACGAACAGCA
GTATAATGATGGTCTCATCACCCAGGGCGAAAAGTACAACAAGGTTGTCGACGCGTGGGGCAAGGCTACCGAAAAGGTCG
CCGAAGAAATGATGGCGCGCATCAAGGCTGTCGAGTTCGATCCGGAAACGGGCCGCCAGAAGCCGATGAACTCTATCTAC
ATGATGTCCCACTCGGGTGCTCGTGGTTCTCCGAACCAGATGCGTCAGCTGGGCGGCATGCGCGGCCTGATGGCCAAGCC
CTCGGGCGAAATCATCGAGACGCCGATCATCTCGAACTTCAAGGAAGGCCTGACCGTTAACGAGTACTTCAACTCGACCC
ACGGTGCCCGTAAGGGTCTTGCAGACACCGCCTTGAAGACCGCAAACTCGGGTTACCTGACCCGTCGTCTCGTCGACGTG
GCGCAGGATTGCATCGTCAACTCCGTGGATTGCGGCACCGACAAGGGCCTCACCATGACCGCCATCGTCGATGCCGGTCA
GATCGTGGCCTCGATTGGCGCCCGTATCCTCGGCCGCACGGCTCTCGACGACATCGACAACCCGGTCACTGGCGAGAACA
TCGTCAAGGCCGGCACGCTGATCGACGAAGCCGACGTTGCCATCATCGAGAAGGCTGGCATCCAGTCCGTCCGCATCCGT
TCGGCTCTGACCTGCGAAGTGCAGATCGGCGTCTGCGGCGTCTGCTATGGTCGTGACCTTGCACGCGGTACGCCTGTCAA
CATGGGCGAGGCCGTTGGCGTCATCGCCGCACAGTCGATCGGTGAACCGGGCACGCAGCTCACCATGCGTACCTTCCACC
TTGGCGGTACGGCTAACGTGGTCGACCAGTCGTTCCTGGAAGCATCGTATGAAGGTACGATCCAGATCAAGAACCGCAAC
ATCCTGCGGAACTCCGAAGGCGTTCTCATCGCCATGGGCCGTAACATGTCCGTTACGATCCTTGATGAGCGCGGCGTCGA
ACGTTCCTCGCAGCGTGTCGCTTACGGTTCGAAGATCTTCGTGGACGATGGCGACAAGGTTAAACGCGGTCAGCGTCTTG
CAGAGTGGGACCCCTACACCCGTCCGATGATGACGGAAGTGGAAGGTACCGTTCACTTCGAGGACCTCGTCGACGGTCTC
TCCGTTCTGGAAGCCACCGACGAATCCACCGGCATCACCAAGCGTCAGGTTATCGACTGGCGTTCGACGCCGCGTGGTTC
GGACCTCAAGCCCGCTATCATCATCAAGGATGCTTCCGGCGCGGTTGCCAAGCTTAGCCGCGGTGGCGAAGCTCGCTTCC
ACCTGTCCGTGGATGCGATCCTCTCGGTCGAACCTGGTTCGAAGGTCTCCCAGGGTGACGTGCTTGCACGTTCGCCGCTG
GAAAGCGCCAAGACGAAGGACATCACCGGTGGTCTGCCGCGCGTTGCCGAACTGTTCGAAGCCCGTCGTCCGAAGGACCA
CGCCATCATCGCAGAGATTGATGGTACGATCCGCCTCGGCCGCGACTACAAGAACAAGCGTCGCGTGATGATCGAGCCTG
CGGAAGACGGCGTCGAGCCGGTCGAATACCTGATCCCGAAGGGCAAGCCCTTCCATCTTCAGGAAGGCGACTACATCGAG
AAGGGCGAATACATTCTCGACGGCAACCCGGCACCGCACGACATTCTGGCGATCAAGGGTGTAGAGGCTCTGGCTTCCTA
CCTCGTGAACGAAATCCAGGAAGTCTACCGACTGCAGGGCGTTGTGATCAACGACAAGCACATCGAGGTGATCGTTCGCC
AGATGCTGCAGAAGGTCGAGATCACCGATGCTGGTGACAGCCAGTACATCGTTGGCGACAATGTCGACCGTATCGAGATG
GAAGACATGAACGACCGTCTCATCGAAGAGGGCAAGAAGCCTGCTTATGGCGAGCCGGTTCTGCTCGGCATCACCAAGGC
TTCGTTGCAGACGCCGTCCTTCATCTCGGCCGCATCCTTCCAGGAAACCACCAAGGTTCTCACGGAAGCTGCGATCGCCG
GCAAGACGGACACGCTGCAGGGCCTTAAGGAAAACGTCATCGTCGGCCGTCTCATCCCGGCCGGCACCGGCGGCACCATG
ACGCAGATCCGCCGCATCGCCACCTCGCGCGACGACCTCATTCTGGAGGAACGCCGCAAGGGTACGGGTGCAGGCTCTGC
GAACCAGATGCTGCAGGACATGACGGACCAGGTTCCAGCCGCCGAATAA

Upstream 100 bases:

>100_bases
GTGCGGTTAAATCCGTATTTAAAGCTCTGGACGGTGACCCGGGAAGAAGCCGGTCCAGATGCAAACAGGGGCAGCAGCTA
GCCTCTCAAGGAGACAAGGC

Downstream 100 bases:

>100_bases
GGTCAGGCAAGGGCAGGGGCTTTACGAAGCCCCGCCATGGTTCAGTAAAAACGCCCGGAGCAATCCGGGCGTTTTTGTTT
GTGCGGACCGGCCGGTGCCT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1402; Mature: 1402

Protein sequence:

>1402_residues
MNQEVMNLFNPQVPAQHFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTSLKQNQL
LSEEEYMIAVDEFGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRAELAETTSDLKQKKFMKRLKIVENFMESGNRPEWMI
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGHPIIVPSQDMVLGLYYLSIMNQNEPGEGMAFSDIGELHHALENKVVTLHAKIRGRFKTVDAD
GKPVSKIHETTPGRMLIGELLPKNVNVPFDTCNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFG
KDDMVIPDSKVKIVGDTEALVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDPETGRQKPMNSIY
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDCIVNSVDCGTDKGLTMTAIVDAGQIVASIGARILGRTALDDIDNPVTGENIVKAGTLIDEADVAIIEKAGIQSVRIR
SALTCEVQIGVCGVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTANVVDQSFLEASYEGTIQIKNRN
ILRNSEGVLIAMGRNMSVTILDERGVERSSQRVAYGSKIFVDDGDKVKRGQRLAEWDPYTRPMMTEVEGTVHFEDLVDGL
SVLEATDESTGITKRQVIDWRSTPRGSDLKPAIIIKDASGAVAKLSRGGEARFHLSVDAILSVEPGSKVSQGDVLARSPL
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVMIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSQYIVGDNVDRIEM
EDMNDRLIEEGKKPAYGEPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDTLQGLKENVIVGRLIPAGTGGTM
TQIRRIATSRDDLILEERRKGTGAGSANQMLQDMTDQVPAAE

Sequences:

>Translated_1402_residues
MNQEVMNLFNPQVPAQHFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTSLKQNQL
LSEEEYMIAVDEFGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRAELAETTSDLKQKKFMKRLKIVENFMESGNRPEWMI
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGHPIIVPSQDMVLGLYYLSIMNQNEPGEGMAFSDIGELHHALENKVVTLHAKIRGRFKTVDAD
GKPVSKIHETTPGRMLIGELLPKNVNVPFDTCNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFG
KDDMVIPDSKVKIVGDTEALVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDPETGRQKPMNSIY
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDCIVNSVDCGTDKGLTMTAIVDAGQIVASIGARILGRTALDDIDNPVTGENIVKAGTLIDEADVAIIEKAGIQSVRIR
SALTCEVQIGVCGVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTANVVDQSFLEASYEGTIQIKNRN
ILRNSEGVLIAMGRNMSVTILDERGVERSSQRVAYGSKIFVDDGDKVKRGQRLAEWDPYTRPMMTEVEGTVHFEDLVDGL
SVLEATDESTGITKRQVIDWRSTPRGSDLKPAIIIKDASGAVAKLSRGGEARFHLSVDAILSVEPGSKVSQGDVLARSPL
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVMIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSQYIVGDNVDRIEM
EDMNDRLIEEGKKPAYGEPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDTLQGLKENVIVGRLIPAGTGGTM
TQIRRIATSRDDLILEERRKGTGAGSANQMLQDMTDQVPAAE
>Mature_1402_residues
MNQEVMNLFNPQVPAQHFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTSLKQNQL
LSEEEYMIAVDEFGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRAELAETTSDLKQKKFMKRLKIVENFMESGNRPEWMI
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGHPIIVPSQDMVLGLYYLSIMNQNEPGEGMAFSDIGELHHALENKVVTLHAKIRGRFKTVDAD
GKPVSKIHETTPGRMLIGELLPKNVNVPFDTCNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFG
KDDMVIPDSKVKIVGDTEALVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDPETGRQKPMNSIY
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDCIVNSVDCGTDKGLTMTAIVDAGQIVASIGARILGRTALDDIDNPVTGENIVKAGTLIDEADVAIIEKAGIQSVRIR
SALTCEVQIGVCGVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTANVVDQSFLEASYEGTIQIKNRN
ILRNSEGVLIAMGRNMSVTILDERGVERSSQRVAYGSKIFVDDGDKVKRGQRLAEWDPYTRPMMTEVEGTVHFEDLVDGL
SVLEATDESTGITKRQVIDWRSTPRGSDLKPAIIIKDASGAVAKLSRGGEARFHLSVDAILSVEPGSKVSQGDVLARSPL
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVMIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSQYIVGDNVDRIEM
EDMNDRLIEEGKKPAYGEPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDTLQGLKENVIVGRLIPAGTGGTM
TQIRRIATSRDDLILEERRKGTGAGSANQMLQDMTDQVPAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI39725938, Length=845, Percent_Identity=25.6804733727811, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI4505939, Length=935, Percent_Identity=24.8128342245989, Blast_Score=165, Evalue=3e-40,
Organism=Homo sapiens, GI103471997, Length=250, Percent_Identity=30.8, Blast_Score=92, Evalue=3e-18,
Organism=Escherichia coli, GI2367335, Length=1372, Percent_Identity=59.402332361516, Blast_Score=1654, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=570, Percent_Identity=25.9649122807018, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25145495, Length=310, Percent_Identity=31.6129032258064, Blast_Score=136, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=893, Percent_Identity=22.508398656215, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324690, Length=693, Percent_Identity=25.5411255411255, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360912, Length=672, Percent_Identity=26.9345238095238, Blast_Score=164, Evalue=4e-40,
Organism=Drosophila melanogaster, GI17530899, Length=491, Percent_Identity=26.8839103869654, Blast_Score=148, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17647875, Length=335, Percent_Identity=26.865671641791, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_AGRT5 (Q8UE09)

Other databases:

- EMBL:   AE007869
- PIR:   AI2816
- PIR:   B97595
- RefSeq:   NP_354930.2
- ProteinModelPortal:   Q8UE09
- STRING:   Q8UE09
- GeneID:   1139411
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1955
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q8UE09
- ProtClustDB:   PRK00566
- BioCyc:   ATUM176299-1:ATU1955-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155518; Mature: 155518

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEVMNLFNPQVPAQHFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCHHHCCCEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRISTLLDMTLKDVERVLYFENYIVTEPGLTSLKQNQLLSEEEYMIAVDEFGEDQFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCHHHH
MIGAEAIYEMLASMNLEKIAGDLRAELAETTSDLKQKKFMKRLKIVENFMESGNRPEWMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHHCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGHPIIVPSQDMVLGLYYLSIMNQNEPGEGMAFSDIGELHHALE
CEEEEEEECCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
NKVVTLHAKIRGRFKTVDADGKPVSKIHETTPGRMLIGELLPKNVNVPFDTCNQEMTKKN
CCEEEEEEEECCEEEEECCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCHHHCCHHHHHHH
ISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFGKDDMVIPDSKVKIVGDTEAL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCEECCCCCEEEEECHHHH
VKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDPETGRQKPMNSIY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEE
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGL
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHCCCHHHHHCCCCHHHCCH
ADTALKTANSGYLTRRLVDVAQDCIVNSVDCGTDKGLTMTAIVDAGQIVASIGARILGRT
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
ALDDIDNPVTGENIVKAGTLIDEADVAIIEKAGIQSVRIRSALTCEVQIGVCGVCYGRDL
HHHHCCCCCCCCHHHHHCCEECCCCCHHHHHCCCCCEEECEEEEEEEEECEEEEECCCHH
ARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTANVVDQSFLEASYEGTIQIKNRN
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCC
ILRNSEGVLIAMGRNMSVTILDERGVERSSQRVAYGSKIFVDDGDKVKRGQRLAEWDPYT
EEECCCCEEEEECCCCEEEEEECCCCCCCCCCEECCCEEEECCCHHHHHCCCCCCCCCCC
RPMMTEVEGTVHFEDLVDGLSVLEATDESTGITKRQVIDWRSTPRGSDLKPAIIIKDASG
CCCHHHCCCCEEHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCCCCCCCCEEEEECCCC
AVAKLSRGGEARFHLSVDAILSVEPGSKVSQGDVLARSPLESAKTKDITGGLPRVAELFE
CHHHHCCCCCEEEEEEEEEEEEECCCCCCCCCCCEECCCHHHCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGTIRLGRDYKNKRRVMIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
HCCCCCCEEEEEECCEEEECCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEECCCCCEEE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVE
CCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCC
ITDAGDSQYIVGDNVDRIEMEDMNDRLIEEGKKPAYGEPVLLGITKASLQTPSFISAASF
CCCCCCCEEEECCCCCEEECCCHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHH
QETTKVLTEAAIAGKTDTLQGLKENVIVGRLIPAGTGGTMTQIRRIATSRDDLILEERRK
HHHHHHHHHHHHCCCCHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHC
GTGAGSANQMLQDMTDQVPAAE
CCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNQEVMNLFNPQVPAQHFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCHHHCCCEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRISTLLDMTLKDVERVLYFENYIVTEPGLTSLKQNQLLSEEEYMIAVDEFGEDQFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCHHHH
MIGAEAIYEMLASMNLEKIAGDLRAELAETTSDLKQKKFMKRLKIVENFMESGNRPEWMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHHCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGHPIIVPSQDMVLGLYYLSIMNQNEPGEGMAFSDIGELHHALE
CEEEEEEECCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
NKVVTLHAKIRGRFKTVDADGKPVSKIHETTPGRMLIGELLPKNVNVPFDTCNQEMTKKN
CCEEEEEEEECCEEEEECCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCHHHCCHHHHHHH
ISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFGKDDMVIPDSKVKIVGDTEAL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCEECCCCCEEEEECHHHH
VKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDPETGRQKPMNSIY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEE
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGL
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHCCCHHHHHCCCCHHHCCH
ADTALKTANSGYLTRRLVDVAQDCIVNSVDCGTDKGLTMTAIVDAGQIVASIGARILGRT
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
ALDDIDNPVTGENIVKAGTLIDEADVAIIEKAGIQSVRIRSALTCEVQIGVCGVCYGRDL
HHHHCCCCCCCCHHHHHCCEECCCCCHHHHHCCCCCEEECEEEEEEEEECEEEEECCCHH
ARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTANVVDQSFLEASYEGTIQIKNRN
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCC
ILRNSEGVLIAMGRNMSVTILDERGVERSSQRVAYGSKIFVDDGDKVKRGQRLAEWDPYT
EEECCCCEEEEECCCCEEEEEECCCCCCCCCCEECCCEEEECCCHHHHHCCCCCCCCCCC
RPMMTEVEGTVHFEDLVDGLSVLEATDESTGITKRQVIDWRSTPRGSDLKPAIIIKDASG
CCCHHHCCCCEEHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCCCCCCCCEEEEECCCC
AVAKLSRGGEARFHLSVDAILSVEPGSKVSQGDVLARSPLESAKTKDITGGLPRVAELFE
CHHHHCCCCCEEEEEEEEEEEEECCCCCCCCCCCEECCCHHHCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGTIRLGRDYKNKRRVMIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
HCCCCCCEEEEEECCEEEECCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEECCCCCEEE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVE
CCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCC
ITDAGDSQYIVGDNVDRIEMEDMNDRLIEEGKKPAYGEPVLLGITKASLQTPSFISAASF
CCCCCCCEEEECCCCCEEECCCHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHH
QETTKVLTEAAIAGKTDTLQGLKENVIVGRLIPAGTGGTMTQIRRIATSRDDLILEERRK
HHHHHHHHHHHHCCCCHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHC
GTGAGSANQMLQDMTDQVPAAE
CCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194