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The map label for this gene is wrbA

Identifier: 159184888

GI number: 159184888

Start: 1713434

End: 1714033

Strand: Reverse

Name: wrbA

Synonym: Atu1728

Alternate gene names: 159184888

Gene position: 1714033-1713434 (Counterclockwise)

Preceding gene: 159184892

Following gene: 15889032

Centisome position: 60.32

GC content: 62.17

Gene sequence:

>600_bases
ATGACGAAGGTTCTGGTACTTTATTACTCCTCTTACGGCCATATCGAGACAATGGCCTATGCGGTTGCCGAAGGCGTGGA
GTCCACCGGCGCGGAAGCCGTGGTCAAGCGCGTTCCCGAACTGGTTCCGGAAGAGGTCGCCAAGTCCTCGCACTTCAAGA
TGGATCAGCCGGCACCGGTGGCGACGGTGGACGAACTGGCCGAATACGATGCCATCATCGTCGGCGCCGGCACGCGTTTC
GGCACGGTCGCCTCGCAGATGCGCAATTTCTGGGACCAGACCGGCGGCCTGTGGTTCAGCGGCAAGCTGGTGGGCAAGGT
CGGCTCGGCCTTTACCTCGTCCGCCACGCAGCACGGCGGTCAGGAATCGACCATTCTCGGTTTCATTCCCACCTTCCTGC
ACCATGGCATGGCCGTCGTCGGTCTGCCCTATGCCTTCCAGGGCCAGATGGGTGTCGATGAAATCAAGGGCGGTTCGCCC
TATGGCGCTTCCACCATCACCGATGGGGACGGCTCGCGTCAGCCTTCCGCAATCGAGCTGGACGCCGCTCGTTATCAGGG
TGCGCATGTCGCCAAGCTGGCCGCCAAGCTTTCCGCTTGA

Upstream 100 bases:

>100_bases
TTCAAATTGAGTTGACGGGTCAACACCGATGATCATCGAGTTTTTGAAGAAGCTTCTGGCCGGTACGCCGGAAACAGTTC
CAGCAAAGGAAACGAAGAGA

Downstream 100 bases:

>100_bases
GCCAGGTTTGATTGAAAAAGAAATGCGGCCCAGAAGGCCGCATTTTCTTTGCGCCGGCATTTGAGACGCCGGGCCTGTGG
AACTTATGGATTTTTAAGGC

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTKVLVLYYSSYGHIETMAYAVAEGVESTGAEAVVKRVPELVPEEVAKSSHFKMDQPAPVATVDELAEYDAIIVGAGTRF
GTVASQMRNFWDQTGGLWFSGKLVGKVGSAFTSSATQHGGQESTILGFIPTFLHHGMAVVGLPYAFQGQMGVDEIKGGSP
YGASTITDGDGSRQPSAIELDAARYQGAHVAKLAAKLSA

Sequences:

>Translated_199_residues
MTKVLVLYYSSYGHIETMAYAVAEGVESTGAEAVVKRVPELVPEEVAKSSHFKMDQPAPVATVDELAEYDAIIVGAGTRF
GTVASQMRNFWDQTGGLWFSGKLVGKVGSAFTSSATQHGGQESTILGFIPTFLHHGMAVVGLPYAFQGQMGVDEIKGGSP
YGASTITDGDGSRQPSAIELDAARYQGAHVAKLAAKLSA
>Mature_198_residues
TKVLVLYYSSYGHIETMAYAVAEGVESTGAEAVVKRVPELVPEEVAKSSHFKMDQPAPVATVDELAEYDAIIVGAGTRFG
TVASQMRNFWDQTGGLWFSGKLVGKVGSAFTSSATQHGGQESTILGFIPTFLHHGMAVVGLPYAFQGQMGVDEIKGGSPY
GASTITDGDGSRQPSAIELDAARYQGAHVAKLAAKLSA

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=199, Percent_Identity=59.2964824120603, Blast_Score=214, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6319849, Length=204, Percent_Identity=42.6470588235294, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=42.2110552763819, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319526, Length=200, Percent_Identity=34, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_AGRT5 (P58795)

Other databases:

- EMBL:   AE007869
- PIR:   AI2788
- PIR:   B97568
- RefSeq:   NP_354714.2
- ProteinModelPortal:   P58795
- SMR:   P58795
- STRING:   P58795
- GeneID:   1133766
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1728
- eggNOG:   COG0655
- HOGENOM:   HBG686708
- OMA:   MAPRIAI
- PhylomeDB:   P58795
- ProtClustDB:   PRK03767
- BioCyc:   ATUM176299-1:ATU1728-MONOMER
- BRENDA:   1.6.5.2
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 20933; Mature: 20802

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLVLYYSSYGHIETMAYAVAEGVESTGAEAVVKRVPELVPEEVAKSSHFKMDQPAPV
CCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ATVDELAEYDAIIVGAGTRFGTVASQMRNFWDQTGGLWFSGKLVGKVGSAFTSSATQHGG
HHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCC
QESTILGFIPTFLHHGMAVVGLPYAFQGQMGVDEIKGGSPYGASTITDGDGSRQPSAIEL
CCCHHHHHHHHHHHCCCEEEECCEEECCCCCHHHCCCCCCCCCCCEECCCCCCCCCEEEE
DAARYQGAHVAKLAAKLSA
HHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TKVLVLYYSSYGHIETMAYAVAEGVESTGAEAVVKRVPELVPEEVAKSSHFKMDQPAPV
CEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ATVDELAEYDAIIVGAGTRFGTVASQMRNFWDQTGGLWFSGKLVGKVGSAFTSSATQHGG
HHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCC
QESTILGFIPTFLHHGMAVVGLPYAFQGQMGVDEIKGGSPYGASTITDGDGSRQPSAIEL
CCCHHHHHHHHHHHCCCEEEECCEEECCCCCHHHCCCCCCCCCCCEECCCCCCCCCEEEE
DAARYQGAHVAKLAAKLSA
HHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194