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The map label for this gene is tolB [C]

Identifier: 159184859

GI number: 159184859

Start: 1640744

End: 1641574

Strand: Reverse

Name: tolB [C]

Synonym: Atu1656

Alternate gene names: 159184859

Gene position: 1641574-1640744 (Counterclockwise)

Preceding gene: 15888965

Following gene: 159184858

Centisome position: 57.77

GC content: 57.28

Gene sequence:

>831_bases
ATGCGCAGTTCCATCGAAATCTTCAACATCCGGACCCGGAAGATGCGGGTGGTCTGGCAGACGCCGGAGCTGTTTGAAGC
GCCGAACTGGTCGCCGGACGGGAAATATCTGCTGTTGAACAGCGAAGGGCTGCTTTATCGCCTGTCACTTGCCGGCGACC
CTTCGCCGGAAAAGGTCGACACCGGCTTTGCGACAATCTGCAATAACGACCACGGCATTTCGCCCGATGGTGCGCTCTAT
GCCATTTCCGACAAGGTGGAGTTCGGCAAGAGCGCGATCTACCTTTTGCCGTCGACGGGCGGCACACCGCGGCTGATGAC
GAAGAACCTTCCCTCCTACTGGCATGGCTGGTCGCCGGACGGGAAAAGTTTTACCTATTGCGGCATTCGCGACCAGGTTT
TCGACATCTATTCCATGGACATAGACAGCGGCGTTGAAACGCGCCTCACCCATGGTGAAGGCCGCAACGACGGCCCGGAT
TATTCGCCGGATGGACGATGGATCTATTTCAACTCCAGCCGAACCGGCCAGATGCAGATTTGGCGCGTGCGGGTGGATGG
TTCCAGCGTCGAGCGCATCACCGACAGCGCCTATGGCGACTGGTTCCCGCATCCGTCTCCTTCGGGTGACAAGGTGGTGT
TCGTTTCTTATGACGCCGATGTCTTCGATCATCCGCGTGATCTCGATGTGCGGGTGCAGCTGATGGATATGGATGGCGGC
AATGTCGAAACGCTGTTCGACCTGTTTGGCGGGCAAGGAACGATGAATTCGCCCAACTGGTCTCCTGATGGCGATGAGTT
TGCTTATGTCAGGTATTTCCCGGTGGAATGA

Upstream 100 bases:

>100_bases
TCCGATTACCAACCGGTTTCGGGATCGGTAAGGTGCGCAAACGGAATGTATGCGCCAGTCGACGCTCCACACCAGACTAT
CGACAGGCCCGGGAGGCAGC

Downstream 100 bases:

>100_bases
TGACGGTAAGGTGCGGCAGGCCACATTGCCGCACCACCCGTGGGACACTTGTGCTTGCAAGCTTTTTTGCCCATAGCTTC
TCCGGTCAGGTGCCCGCCCT

Product: tolB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRSSIEIFNIRTRKMRVVWQTPELFEAPNWSPDGKYLLLNSEGLLYRLSLAGDPSPEKVDTGFATICNNDHGISPDGALY
AISDKVEFGKSAIYLLPSTGGTPRLMTKNLPSYWHGWSPDGKSFTYCGIRDQVFDIYSMDIDSGVETRLTHGEGRNDGPD
YSPDGRWIYFNSSRTGQMQIWRVRVDGSSVERITDSAYGDWFPHPSPSGDKVVFVSYDADVFDHPRDLDVRVQLMDMDGG
NVETLFDLFGGQGTMNSPNWSPDGDEFAYVRYFPVE

Sequences:

>Translated_276_residues
MRSSIEIFNIRTRKMRVVWQTPELFEAPNWSPDGKYLLLNSEGLLYRLSLAGDPSPEKVDTGFATICNNDHGISPDGALY
AISDKVEFGKSAIYLLPSTGGTPRLMTKNLPSYWHGWSPDGKSFTYCGIRDQVFDIYSMDIDSGVETRLTHGEGRNDGPD
YSPDGRWIYFNSSRTGQMQIWRVRVDGSSVERITDSAYGDWFPHPSPSGDKVVFVSYDADVFDHPRDLDVRVQLMDMDGG
NVETLFDLFGGQGTMNSPNWSPDGDEFAYVRYFPVE
>Mature_276_residues
MRSSIEIFNIRTRKMRVVWQTPELFEAPNWSPDGKYLLLNSEGLLYRLSLAGDPSPEKVDTGFATICNNDHGISPDGALY
AISDKVEFGKSAIYLLPSTGGTPRLMTKNLPSYWHGWSPDGKSFTYCGIRDQVFDIYSMDIDSGVETRLTHGEGRNDGPD
YSPDGRWIYFNSSRTGQMQIWRVRVDGSSVERITDSAYGDWFPHPSPSGDKVVFVSYDADVFDHPRDLDVRVQLMDMDGG
NVETLFDLFGGQGTMNSPNWSPDGDEFAYVRYFPVE

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1656_AGRT5 (Q8UEU8)

Other databases:

- EMBL:   AE007869
- PIR:   AC2780
- PIR:   E97559
- RefSeq:   NP_354645.2
- PDB:   2OJH
- PDBsum:   2OJH
- ProteinModelPortal:   Q8UEU8
- SMR:   Q8UEU8
- STRING:   Q8UEU8
- GeneID:   1133694
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1656
- eggNOG:   COG0823
- HOGENOM:   HBG299282
- OMA:   NDHGISP
- ProtClustDB:   CLSK800403
- BioCyc:   ATUM176299-1:ATU1656-MONOMER
- InterPro:   IPR011042
- InterPro:   IPR011659
- Gene3D:   G3DSA:2.120.10.30

Pfam domain/function: PF07676 PD40

EC number: NA

Molecular weight: Translated: 31105; Mature: 31105

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSIEIFNIRTRKMRVVWQTPELFEAPNWSPDGKYLLLNSEGLLYRLSLAGDPSPEKVD
CCCCEEEEEEEEEEEEEEEECCHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCC
TGFATICNNDHGISPDGALYAISDKVEFGKSAIYLLPSTGGTPRLMTKNLPSYWHGWSPD
CCEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCC
GKSFTYCGIRDQVFDIYSMDIDSGVETRLTHGEGRNDGPDYSPDGRWIYFNSSRTGQMQI
CCEEEEECCCHHEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEE
WRVRVDGSSVERITDSAYGDWFPHPSPSGDKVVFVSYDADVFDHPRDLDVRVQLMDMDGG
EEEEECCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCCCEEEEEEEECCCC
NVETLFDLFGGQGTMNSPNWSPDGDEFAYVRYFPVE
CHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MRSSIEIFNIRTRKMRVVWQTPELFEAPNWSPDGKYLLLNSEGLLYRLSLAGDPSPEKVD
CCCCEEEEEEEEEEEEEEEECCHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCC
TGFATICNNDHGISPDGALYAISDKVEFGKSAIYLLPSTGGTPRLMTKNLPSYWHGWSPD
CCEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCC
GKSFTYCGIRDQVFDIYSMDIDSGVETRLTHGEGRNDGPDYSPDGRWIYFNSSRTGQMQI
CCEEEEECCCHHEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEE
WRVRVDGSSVERITDSAYGDWFPHPSPSGDKVVFVSYDADVFDHPRDLDVRVQLMDMDGG
EEEEECCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCCCEEEEEEEECCCC
NVETLFDLFGGQGTMNSPNWSPDGDEFAYVRYFPVE
CHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194