Click here to switch to the map view.

The map label for this gene is phbC [H]

Identifier: 159184834

GI number: 159184834

Start: 1585294

End: 1587153

Strand: Direct

Name: phbC [H]

Synonym: Atu1604

Alternate gene names: 159184834

Gene position: 1585294-1587153 (Clockwise)

Preceding gene: 15888914

Following gene: 15888918

Centisome position: 55.79

GC content: 60.75

Gene sequence:

>1860_bases
ATGGCAGGTGTTGACGGCGGGGCTGGGAAAAAGGGTGGCAAAACGCCCGGCTTCGACGCCAGTACCGCCGAGGCCTACCT
GATCCGCGACCCCGAAACCTTCGCGATCAATGTCGCCCGCGCGCTCGAAAACCTCGGCAAGGCCGCCTCCGAATGGTTGG
CGCCGCGCGAACGCGGCGAAATTCCACAGGCAAGCGCCGATCCGGTAACCGATCTGGTCAAGACGCTGTCGGATGTCGCC
GAATATTGGATGGCCGAACCGAAGCGGTCGCTGGAGGCGCAGACCCATCTTCTCTCCAGCTATTACGATCTTTGGACGAA
ATCGCTGGCGCAATTTTCCAATGACGCCGATTCGCCCCCGGAAAATGTGGCCGAAAGCGGCCCTGCACAGCGCAGAAGCA
AGCGTTTTGCCGATGCCGACTGGCAGACCAATCCGTTCTTCGATTTCCTGCTGAAAGCCTACCAGACCACCGTCGGTTTC
GCCGACCGGATGGTGACGGAAGCCGATGGGCTGGATGAGCATACCCGCACCAAGGCGCTGTTCTACATGCGGCAGGTGAC
GGAGGCGCTTTCGCCGGCCAATTTCGTCTTCACCAACCCGCAGGTTTTTCGCGAGACGGTGGCCTCCAGTGGCGCCAATC
TTGTCAAGGGTATGGCGCAGCTGGCCGAGGATGTCGCGGCCGGCAATGGCCATCTGAAACTGCGCCAGACCGATTACAGC
AAATTCGTCATCGGCCAGAACATTGCCGTCACGCCTGGGAAGGTCGTGGCGAAAAGCCCGCTCTGCGAAATCATCCATTA
TGCGCCGACGACGGAAAAGGTCTTCAAACCGCCGCTGCTGATCGTGCCGCCCTGGATCAACAAATTCTACATTCTCGATC
TCAACCCGCAGAAATCCTTCGTCGGCTGGTGCCTCGAGCAGGGCCACAGCGTGTTCATGGTCTCCTGGATCAACCCGGAC
GCCGGCCTCGCCAACAAGGGCTGGGACGATTATATCAATGAGGGCATCGATTTTGCCCTCGACACCATCGAGGAGCGCAC
CGGCGAGAAGCAAATCAACGCCATCGGTTATTGCGTCGGCGGCACGCTGTTATCCTCGGCGCTGGCGCTGCATGCGCAGC
AGGGCAATGAGCGTATCCGCAGCGCCACGCTGCTCGCCGCCCAGACCGATTTCATCCATGCCGGCGATCTCAAGGTCTTC
ATCGATGAAGGCCAGCTGGCGGCGCTGGACAAGCACATGCAGGCGGTCGGTTATCTCGATGGCTCGATCATGGCCACCGT
CTTCAACATGTTGCGCGCTTCCGACCTCATCTGGCCCTATGTGGTCGATAATTACCTGCGCGGCGCCGAGCCCCTCCCCT
TCGATCTCCTCTACTGGAATTCCGATTCGACCCGGGTGACGGCCGCCAGTCATTCCTTCTATCTGCGCAATTGTTACCTC
GAGAACAATCTCGCCCGCGGGCTGATGCGCGTTGCCGGCAAGCGCATCAATCTCGGCGATATCACGATACCCGTCTACGA
TCTCGCCACCCGCGACGATCATATCGCGCCGGCGAAATCGGTCTTCACGGGTGCTGCCCTGTTCGGCGGAACGGTGGAAT
TCGTGCTCGGCGCGTCAGGCCACATTGCCGGTGTCATCAACCCGCCGCAGCTTGAGAAATACCAATATTGGACAGGCCCG
TCACCATCAGGAGACTTCGAGGCCTGGCAGGCGGCCGCCACGGCCCATAAGGGTTCCTGGTGGATGCACTGGCAGAACTG
GATCGAAAGCCAGAGCACCGAGAAGGTGAAGGCGCGTAAGCCGGGAGACGGCAAGCGCCCGGTGCTCGGCGACGCGCCGG
GAACCTACGTCCTTTCCTGA

Upstream 100 bases:

>100_bases
TCGACTGCGGTTCGGCGCTTTACGAGCCTCCCCTTGCTGGTGGAACTTGTATTCGTTTTCATGCAGAATGTGCAAACACA
AATTTGGTGGAGGATCGTGC

Downstream 100 bases:

>100_bases
TCTCATCCGCCACTCTCATTTTTCAGGCCACATGCTCTTCACGCCTCCGCTCATTCCCGCCACACTGATTTCCCGCTACA
AGCGTTTCCTGTTCGATGCC

Product: poly-beta-hydroxybutyrate synthase

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MAGVDGGAGKKGGKTPGFDASTAEAYLIRDPETFAINVARALENLGKAASEWLAPRERGEIPQASADPVTDLVKTLSDVA
EYWMAEPKRSLEAQTHLLSSYYDLWTKSLAQFSNDADSPPENVAESGPAQRRSKRFADADWQTNPFFDFLLKAYQTTVGF
ADRMVTEADGLDEHTRTKALFYMRQVTEALSPANFVFTNPQVFRETVASSGANLVKGMAQLAEDVAAGNGHLKLRQTDYS
KFVIGQNIAVTPGKVVAKSPLCEIIHYAPTTEKVFKPPLLIVPPWINKFYILDLNPQKSFVGWCLEQGHSVFMVSWINPD
AGLANKGWDDYINEGIDFALDTIEERTGEKQINAIGYCVGGTLLSSALALHAQQGNERIRSATLLAAQTDFIHAGDLKVF
IDEGQLAALDKHMQAVGYLDGSIMATVFNMLRASDLIWPYVVDNYLRGAEPLPFDLLYWNSDSTRVTAASHSFYLRNCYL
ENNLARGLMRVAGKRINLGDITIPVYDLATRDDHIAPAKSVFTGAALFGGTVEFVLGASGHIAGVINPPQLEKYQYWTGP
SPSGDFEAWQAAATAHKGSWWMHWQNWIESQSTEKVKARKPGDGKRPVLGDAPGTYVLS

Sequences:

>Translated_619_residues
MAGVDGGAGKKGGKTPGFDASTAEAYLIRDPETFAINVARALENLGKAASEWLAPRERGEIPQASADPVTDLVKTLSDVA
EYWMAEPKRSLEAQTHLLSSYYDLWTKSLAQFSNDADSPPENVAESGPAQRRSKRFADADWQTNPFFDFLLKAYQTTVGF
ADRMVTEADGLDEHTRTKALFYMRQVTEALSPANFVFTNPQVFRETVASSGANLVKGMAQLAEDVAAGNGHLKLRQTDYS
KFVIGQNIAVTPGKVVAKSPLCEIIHYAPTTEKVFKPPLLIVPPWINKFYILDLNPQKSFVGWCLEQGHSVFMVSWINPD
AGLANKGWDDYINEGIDFALDTIEERTGEKQINAIGYCVGGTLLSSALALHAQQGNERIRSATLLAAQTDFIHAGDLKVF
IDEGQLAALDKHMQAVGYLDGSIMATVFNMLRASDLIWPYVVDNYLRGAEPLPFDLLYWNSDSTRVTAASHSFYLRNCYL
ENNLARGLMRVAGKRINLGDITIPVYDLATRDDHIAPAKSVFTGAALFGGTVEFVLGASGHIAGVINPPQLEKYQYWTGP
SPSGDFEAWQAAATAHKGSWWMHWQNWIESQSTEKVKARKPGDGKRPVLGDAPGTYVLS
>Mature_618_residues
AGVDGGAGKKGGKTPGFDASTAEAYLIRDPETFAINVARALENLGKAASEWLAPRERGEIPQASADPVTDLVKTLSDVAE
YWMAEPKRSLEAQTHLLSSYYDLWTKSLAQFSNDADSPPENVAESGPAQRRSKRFADADWQTNPFFDFLLKAYQTTVGFA
DRMVTEADGLDEHTRTKALFYMRQVTEALSPANFVFTNPQVFRETVASSGANLVKGMAQLAEDVAAGNGHLKLRQTDYSK
FVIGQNIAVTPGKVVAKSPLCEIIHYAPTTEKVFKPPLLIVPPWINKFYILDLNPQKSFVGWCLEQGHSVFMVSWINPDA
GLANKGWDDYINEGIDFALDTIEERTGEKQINAIGYCVGGTLLSSALALHAQQGNERIRSATLLAAQTDFIHAGDLKVFI
DEGQLAALDKHMQAVGYLDGSIMATVFNMLRASDLIWPYVVDNYLRGAEPLPFDLLYWNSDSTRVTAASHSFYLRNCYLE
NNLARGLMRVAGKRINLGDITIPVYDLATRDDHIAPAKSVFTGAALFGGTVEFVLGASGHIAGVINPPQLEKYQYWTGPS
PSGDFEAWQAAATAHKGSWWMHWQNWIESQSTEKVKARKPGDGKRPVLGDAPGTYVLS

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 67971; Mature: 67840

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVDGGAGKKGGKTPGFDASTAEAYLIRDPETFAINVARALENLGKAASEWLAPRERGE
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHCCC
IPQASADPVTDLVKTLSDVAEYWMAEPKRSLEAQTHLLSSYYDLWTKSLAQFSNDADSPP
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ENVAESGPAQRRSKRFADADWQTNPFFDFLLKAYQTTVGFADRMVTEADGLDEHTRTKAL
HHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FYMRQVTEALSPANFVFTNPQVFRETVASSGANLVKGMAQLAEDVAAGNGHLKLRQTDYS
HHHHHHHHHCCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
KFVIGQNIAVTPGKVVAKSPLCEIIHYAPTTEKVFKPPLLIVPPWINKFYILDLNPQKSF
EEEECCCEEECCCCHHHCCHHHHHHHCCCCCHHHHCCCEEEECCCCCEEEEEECCCCHHH
VGWCLEQGHSVFMVSWINPDAGLANKGWDDYINEGIDFALDTIEERTGEKQINAIGYCVG
HHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
GTLLSSALALHAQQGNERIRSATLLAAQTDFIHAGDLKVFIDEGQLAALDKHMQAVGYLD
HHHHHHHHHHHHHHCHHHHHHHHHEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHCCC
GSIMATVFNMLRASDLIWPYVVDNYLRGAEPLPFDLLYWNSDSTRVTAASHSFYLRNCYL
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEEEEHHHH
ENNLARGLMRVAGKRINLGDITIPVYDLATRDDHIAPAKSVFTGAALFGGTVEFVLGASG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCC
HIAGVINPPQLEKYQYWTGPSPSGDFEAWQAAATAHKGSWWMHWQNWIESQSTEKVKARK
CEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHCCCCCCHHHCCC
PGDGKRPVLGDAPGTYVLS
CCCCCCCCCCCCCCCEEEC
>Mature Secondary Structure 
AGVDGGAGKKGGKTPGFDASTAEAYLIRDPETFAINVARALENLGKAASEWLAPRERGE
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHCCC
IPQASADPVTDLVKTLSDVAEYWMAEPKRSLEAQTHLLSSYYDLWTKSLAQFSNDADSPP
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ENVAESGPAQRRSKRFADADWQTNPFFDFLLKAYQTTVGFADRMVTEADGLDEHTRTKAL
HHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FYMRQVTEALSPANFVFTNPQVFRETVASSGANLVKGMAQLAEDVAAGNGHLKLRQTDYS
HHHHHHHHHCCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
KFVIGQNIAVTPGKVVAKSPLCEIIHYAPTTEKVFKPPLLIVPPWINKFYILDLNPQKSF
EEEECCCEEECCCCHHHCCHHHHHHHCCCCCHHHHCCCEEEECCCCCEEEEEECCCCHHH
VGWCLEQGHSVFMVSWINPDAGLANKGWDDYINEGIDFALDTIEERTGEKQINAIGYCVG
HHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
GTLLSSALALHAQQGNERIRSATLLAAQTDFIHAGDLKVFIDEGQLAALDKHMQAVGYLD
HHHHHHHHHHHHHHCHHHHHHHHHEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHCCC
GSIMATVFNMLRASDLIWPYVVDNYLRGAEPLPFDLLYWNSDSTRVTAASHSFYLRNCYL
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEEEEHHHH
ENNLARGLMRVAGKRINLGDITIPVYDLATRDDHIAPAKSVFTGAALFGGTVEFVLGASG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCC
HIAGVINPPQLEKYQYWTGPSPSGDFEAWQAAATAHKGSWWMHWQNWIESQSTEKVKARK
CEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHCCCCCCHHHCCC
PGDGKRPVLGDAPGTYVLS
CCCCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8626293 [H]