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The map label for this gene is znuA [H]

Identifier: 159184797

GI number: 159184797

Start: 1510841

End: 1511830

Strand: Direct

Name: znuA [H]

Synonym: Atu1521

Alternate gene names: 159184797

Gene position: 1510841-1511830 (Clockwise)

Preceding gene: 159184795

Following gene: 159184799

Centisome position: 53.17

GC content: 60.81

Gene sequence:

>990_bases
ATGAAATCGATCCTGATCCCGCTCATGGCGTCGGCGGCACTAGCAGCCGTCGCTTCGGGCGCTACCGCCGCGCCCGATGT
CGTGGTCTCGATCAAGCCTGTCCACTCCCTCGTTGCAGCCATCATGAAGGGTGTGGGCGAACCGCAGCTCATCGTCGACG
GCGCGGCCTCGCCGCATACTTATAATCTCCGGCCCTCCAATGCACGCAAGCTCGAAAAGGCGGATGTGGTGTTTTGGGTC
GGCCCCGGACTGGAAGCCTTTCTGCAAAAGCCGCTGGAAGCGCTGGCCAGCAAGGCGACCGTGGTGGAGCTAGAAGATGC
CAAGGGTCTCGAAAAACTGCCCTTCCGAAAGGGCGGCCCCTTCGAGGCGCACGATGATGGTGAAGAAGGCCATGAGGCGC
ATGCGGGCCACACCGAAGACGAAGGTGCGCATGATCATGGAAACGACCATGCCGGTTCCGAGGAGCACGAGCACGGCGCG
TATGACACGCATCTCTGGCTCGACCCTGCCAACGCCAAGGCAATGGCCCAGGCGATCGAAACGGCTCTGATTGCGGCCGA
TGCCGGCAATGCCGCGACCTATCAGGCCAACACCAAGAAGCTGATCGATGATCTCGATGCGCTCGACGCCGAAGTCGTAG
AGACGGTGAAACCGGTGAAGGACAAGCCCTTCATCGTTTTCCACGATGCTTATCAATATTTCGAGCATCGTTATGGCGTG
AAAACCGCGGGATCGATCACCGTCAGCCCCGAAACCCTGCCGGGCGCGGATCGCGTCAAACAGATGCAGGAGAAGGTTCG
CCAGCTGGGCGCACCCTGCGTTTTCGCCGAACCGCAATTCGAGCCGAAACTGGTCTCGGTCATCACCGAAGGCACGGCAG
CGAAATCGGCGACGCTCGATCCGGAAGCGGCGACACTCACGCCCGGCCCCGATCTTTATTTCAAGCTGATGCGCGGCATT
GCCGGTTCGCTCAAGAACTGCCTGTCCTGA

Upstream 100 bases:

>100_bases
TTGTCCGTTCAGCGATGTTGCCTACCGCTATTGCATACGTTATAGAGTTACGCAATAAATGTAATAACATAACTATACTT
GTTCAAGTGGAGTGCATTTC

Downstream 100 bases:

>100_bases
TCGGAAACAGCGCCGGATTTCCTATGGCTTGGGCGCCATCGACGACCAGACCGGCCCGCTGATGCTCTGCAGCGTTTCAG
CAGCTTCACCATTGATGCGG

Product: ABC transporter, substrate binding protein (zinc)

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKSILIPLMASAALAAVASGATAAPDVVVSIKPVHSLVAAIMKGVGEPQLIVDGAASPHTYNLRPSNARKLEKADVVFWV
GPGLEAFLQKPLEALASKATVVELEDAKGLEKLPFRKGGPFEAHDDGEEGHEAHAGHTEDEGAHDHGNDHAGSEEHEHGA
YDTHLWLDPANAKAMAQAIETALIAADAGNAATYQANTKKLIDDLDALDAEVVETVKPVKDKPFIVFHDAYQYFEHRYGV
KTAGSITVSPETLPGADRVKQMQEKVRQLGAPCVFAEPQFEPKLVSVITEGTAAKSATLDPEAATLTPGPDLYFKLMRGI
AGSLKNCLS

Sequences:

>Translated_329_residues
MKSILIPLMASAALAAVASGATAAPDVVVSIKPVHSLVAAIMKGVGEPQLIVDGAASPHTYNLRPSNARKLEKADVVFWV
GPGLEAFLQKPLEALASKATVVELEDAKGLEKLPFRKGGPFEAHDDGEEGHEAHAGHTEDEGAHDHGNDHAGSEEHEHGA
YDTHLWLDPANAKAMAQAIETALIAADAGNAATYQANTKKLIDDLDALDAEVVETVKPVKDKPFIVFHDAYQYFEHRYGV
KTAGSITVSPETLPGADRVKQMQEKVRQLGAPCVFAEPQFEPKLVSVITEGTAAKSATLDPEAATLTPGPDLYFKLMRGI
AGSLKNCLS
>Mature_329_residues
MKSILIPLMASAALAAVASGATAAPDVVVSIKPVHSLVAAIMKGVGEPQLIVDGAASPHTYNLRPSNARKLEKADVVFWV
GPGLEAFLQKPLEALASKATVVELEDAKGLEKLPFRKGGPFEAHDDGEEGHEAHAGHTEDEGAHDHGNDHAGSEEHEHGA
YDTHLWLDPANAKAMAQAIETALIAADAGNAATYQANTKKLIDDLDALDAEVVETVKPVKDKPFIVFHDAYQYFEHRYGV
KTAGSITVSPETLPGADRVKQMQEKVRQLGAPCVFAEPQFEPKLVSVITEGTAAKSATLDPEAATLTPGPDLYFKLMRGI
AGSLKNCLS

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=313, Percent_Identity=37.0607028753994, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34919; Mature: 34919

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILIPLMASAALAAVASGATAAPDVVVSIKPVHSLVAAIMKGVGEPQLIVDGAASPHT
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCE
YNLRPSNARKLEKADVVFWVGPGLEAFLQKPLEALASKATVVELEDAKGLEKLPFRKGGP
ECCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHCCCCCCCC
FEAHDDGEEGHEAHAGHTEDEGAHDHGNDHAGSEEHEHGAYDTHLWLDPANAKAMAQAIE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHH
TALIAADAGNAATYQANTKKLIDDLDALDAEVVETVKPVKDKPFIVFHDAYQYFEHRYGV
HHHHEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCC
KTAGSITVSPETLPGADRVKQMQEKVRQLGAPCVFAEPQFEPKLVSVITEGTAAKSATLD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCCCCCCCC
PEAATLTPGPDLYFKLMRGIAGSLKNCLS
CCCCEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSILIPLMASAALAAVASGATAAPDVVVSIKPVHSLVAAIMKGVGEPQLIVDGAASPHT
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCE
YNLRPSNARKLEKADVVFWVGPGLEAFLQKPLEALASKATVVELEDAKGLEKLPFRKGGP
ECCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHCCCCCCCC
FEAHDDGEEGHEAHAGHTEDEGAHDHGNDHAGSEEHEHGAYDTHLWLDPANAKAMAQAIE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHH
TALIAADAGNAATYQANTKKLIDDLDALDAEVVETVKPVKDKPFIVFHDAYQYFEHRYGV
HHHHEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCC
KTAGSITVSPETLPGADRVKQMQEKVRQLGAPCVFAEPQFEPKLVSVITEGTAAKSATLD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCCCCCCCC
PEAATLTPGPDLYFKLMRGIAGSLKNCLS
CCCCEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA