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The map label for this gene is gcvT [H]

Identifier: 159184753

GI number: 159184753

Start: 1416488

End: 1417903

Strand: Direct

Name: gcvT [H]

Synonym: Atu1420

Alternate gene names: 159184753

Gene position: 1416488-1417903 (Clockwise)

Preceding gene: 15888746

Following gene: 15888750

Centisome position: 49.85

GC content: 56.99

Gene sequence:

>1416_bases
ATGGCAAATTCCAGTCTGACCGAGGTTTTGAAGCAATATCCGAACCCCGTTGAAATGCTCCGCAACTCAAAAATCGGAAT
GTATGTATACCCGGTTGTCGCCGGTGAGTTCAGCAACTGGCGTTCCGAGCAGGCCGCATGGCGCGAGGGTGCCGTGTTGT
TTGACCAGTCCCACCACATGGACGAATTGATCGTTGAAGGGCCCGATGCGGAGAAATTCCTTGCCTATCACGGCATCAAC
TCCTTTTCGAATTTCGATCTCAACCGCGCCAAGCATTTCGTTCCGGTAACTCCTGATGGTCACGTCATTGGTGACCACAT
CATTTTCCGCGAGCGTCAGGACAAGTTCATCCTCGTCGGCCGCGCTCCGACCTCGAGCTGGCTGATGTTCTGCGCTGCCT
ATGGCAAGTGGAATGTGCGTATCAAGCATGATCCTCGGTCTCCGTCGCGGCCGGAAGGCGAGCGTGTGCTTCGCACCCAC
TACCGCTACCAGATCCAGGGACCGGATGCCCCGAAGATCTTCGAGAAGATGAATGGTGGGCCGATCCCGGATATCAAGTT
CTTCCATGTCGACTGGATCAATATCGGCTCGAAGAAAGTACAGGCGCTGCGTCACGGCATGTCCGGCGCGCCCGGTCTCG
AAGTATGGGGACCGTATGAGGACAAGAGCTACATCCTGTCCTGCATCCTCGAGGCAGCCAAACAGGCCGGCGTCAATCTC
GTGCGCTGCGGCAGCCGGGCCTATTCCACCAACACGCTCGAATCGGGCTGGATCCCGTCGCCTCTGCCGGGCATTTACAC
CGGCGACGGCATGCTGAAGGATTATCGCGACTGGCTGGGCGCGGATAGCTACGAGGCCACGGGCGCGATCGGCGGAAGCT
TCGTTTCCGAGAATATCGAGGACTATTACGTCAATCCGTTCGAACTCGGTTATGACTTCTATATTGGCTGGAAGAAGGAC
GATTTCATTGGCAAGTCGGCGCTCGAGGCCATGAAGGGCAAAACGCATCGCAAGAAGGTGACCTTCGAATGGAATGCAGA
GGATGTCGTTGACGTCATCGCCTCAGCCTTCCGTCCTGGCGAAGACCATTACAAGTGGATCGATTTCCCGCAGGCCAATT
ACGCTTCGACGGGCGCAGACCTTATCCTGAAGGGCGGCAAACATGTGGGGATGTCGATGTTCACCGGCTATTCCTATAAT
GAGCGCTGCATATTGTCGCTCGGCATCGTCGACAATGACATCCAGATCGGCGACGTTCTCACGCTTGTCTGGGGCGAGCC
AGATGGCGGCTCCGCCAAGACCTCGACGGAGCGCCACAAGCAGAAGGAAATCCGCGTCCGCGTTTCAGAAACGCCTTACG
CCGCGGAAGCACGCGACAATTACGCCGACAGCTGGCGCACCAAAAAGGCGTCCTGA

Upstream 100 bases:

>100_bases
TTGTCGACACCCTCCCTGACGCGGTAATTTTGCGCTTGCAATTTATCAAAGCACAGCGTTTCATGTATACATAGATGCGA
TTGCCAGGGAGGAGATGACA

Downstream 100 bases:

>100_bases
GAAGGCTCCGTCTGCCCGCGCCCGTTCGCGCGGCACCATATGAAGCGATCAAAAAAAACAAGGCCCGCCGGAACCGGTGG
GCCTTTGCTATTGTGAAAAG

Product: glycine cleavage system T protein, aminomethyltransferase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MANSSLTEVLKQYPNPVEMLRNSKIGMYVYPVVAGEFSNWRSEQAAWREGAVLFDQSHHMDELIVEGPDAEKFLAYHGIN
SFSNFDLNRAKHFVPVTPDGHVIGDHIIFRERQDKFILVGRAPTSSWLMFCAAYGKWNVRIKHDPRSPSRPEGERVLRTH
YRYQIQGPDAPKIFEKMNGGPIPDIKFFHVDWINIGSKKVQALRHGMSGAPGLEVWGPYEDKSYILSCILEAAKQAGVNL
VRCGSRAYSTNTLESGWIPSPLPGIYTGDGMLKDYRDWLGADSYEATGAIGGSFVSENIEDYYVNPFELGYDFYIGWKKD
DFIGKSALEAMKGKTHRKKVTFEWNAEDVVDVIASAFRPGEDHYKWIDFPQANYASTGADLILKGGKHVGMSMFTGYSYN
ERCILSLGIVDNDIQIGDVLTLVWGEPDGGSAKTSTERHKQKEIRVRVSETPYAAEARDNYADSWRTKKAS

Sequences:

>Translated_471_residues
MANSSLTEVLKQYPNPVEMLRNSKIGMYVYPVVAGEFSNWRSEQAAWREGAVLFDQSHHMDELIVEGPDAEKFLAYHGIN
SFSNFDLNRAKHFVPVTPDGHVIGDHIIFRERQDKFILVGRAPTSSWLMFCAAYGKWNVRIKHDPRSPSRPEGERVLRTH
YRYQIQGPDAPKIFEKMNGGPIPDIKFFHVDWINIGSKKVQALRHGMSGAPGLEVWGPYEDKSYILSCILEAAKQAGVNL
VRCGSRAYSTNTLESGWIPSPLPGIYTGDGMLKDYRDWLGADSYEATGAIGGSFVSENIEDYYVNPFELGYDFYIGWKKD
DFIGKSALEAMKGKTHRKKVTFEWNAEDVVDVIASAFRPGEDHYKWIDFPQANYASTGADLILKGGKHVGMSMFTGYSYN
ERCILSLGIVDNDIQIGDVLTLVWGEPDGGSAKTSTERHKQKEIRVRVSETPYAAEARDNYADSWRTKKAS
>Mature_470_residues
ANSSLTEVLKQYPNPVEMLRNSKIGMYVYPVVAGEFSNWRSEQAAWREGAVLFDQSHHMDELIVEGPDAEKFLAYHGINS
FSNFDLNRAKHFVPVTPDGHVIGDHIIFRERQDKFILVGRAPTSSWLMFCAAYGKWNVRIKHDPRSPSRPEGERVLRTHY
RYQIQGPDAPKIFEKMNGGPIPDIKFFHVDWINIGSKKVQALRHGMSGAPGLEVWGPYEDKSYILSCILEAAKQAGVNLV
RCGSRAYSTNTLESGWIPSPLPGIYTGDGMLKDYRDWLGADSYEATGAIGGSFVSENIEDYYVNPFELGYDFYIGWKKDD
FIGKSALEAMKGKTHRKKVTFEWNAEDVVDVIASAFRPGEDHYKWIDFPQANYASTGADLILKGGKHVGMSMFTGYSYNE
RCILSLGIVDNDIQIGDVLTLVWGEPDGGSAKTSTERHKQKEIRVRVSETPYAAEARDNYADSWRTKKAS

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 53055; Mature: 52924

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSSLTEVLKQYPNPVEMLRNSKIGMYVYPVVAGEFSNWRSEQAAWREGAVLFDQSHHM
CCCCHHHHHHHHCCCHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEECCCCC
DELIVEGPDAEKFLAYHGINSFSNFDLNRAKHFVPVTPDGHVIGDHIIFRERQDKFILVG
CHHEEECCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEECCEEEEEECCCCEEEEE
RAPTSSWLMFCAAYGKWNVRIKHDPRSPSRPEGERVLRTHYRYQIQGPDAPKIFEKMNGG
CCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHEEEEEEEECCCCCHHHHHHCCCC
PIPDIKFFHVDWINIGSKKVQALRHGMSGAPGLEVWGPYEDKSYILSCILEAAKQAGVNL
CCCCEEEEEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
VRCGSRAYSTNTLESGWIPSPLPGIYTGDGMLKDYRDWLGADSYEATGAIGGSFVSENIE
EEECCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCH
DYYVNPFELGYDFYIGWKKDDFIGKSALEAMKGKTHRKKVTFEWNAEDVVDVIASAFRPG
HHCCCHHHCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCCC
EDHYKWIDFPQANYASTGADLILKGGKHVGMSMFTGYSYNERCILSLGIVDNDIQIGDVL
CCCCEEECCCCCCCCCCCCEEEEECCCCCCHHEEECCCCCCEEEEEEEEECCCEEECEEE
TLVWGEPDGGSAKTSTERHKQKEIRVRVSETPYAAEARDNYADSWRTKKAS
EEEECCCCCCCCCCCHHHHHCEEEEEEECCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
ANSSLTEVLKQYPNPVEMLRNSKIGMYVYPVVAGEFSNWRSEQAAWREGAVLFDQSHHM
CCCHHHHHHHHCCCHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEECCCCC
DELIVEGPDAEKFLAYHGINSFSNFDLNRAKHFVPVTPDGHVIGDHIIFRERQDKFILVG
CHHEEECCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEECCEEEEEECCCCEEEEE
RAPTSSWLMFCAAYGKWNVRIKHDPRSPSRPEGERVLRTHYRYQIQGPDAPKIFEKMNGG
CCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHEEEEEEEECCCCCHHHHHHCCCC
PIPDIKFFHVDWINIGSKKVQALRHGMSGAPGLEVWGPYEDKSYILSCILEAAKQAGVNL
CCCCEEEEEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
VRCGSRAYSTNTLESGWIPSPLPGIYTGDGMLKDYRDWLGADSYEATGAIGGSFVSENIE
EEECCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCH
DYYVNPFELGYDFYIGWKKDDFIGKSALEAMKGKTHRKKVTFEWNAEDVVDVIASAFRPG
HHCCCHHHCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCCC
EDHYKWIDFPQANYASTGADLILKGGKHVGMSMFTGYSYNERCILSLGIVDNDIQIGDVL
CCCCEEECCCCCCCCCCCCEEEEECCCCCCHHEEECCCCCCEEEEEEEEECCCEEECEEE
TLVWGEPDGGSAKTSTERHKQKEIRVRVSETPYAAEARDNYADSWRTKKAS
EEEECCCCCCCCCCCHHHHHCEEEEEEECCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]