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The map label for this gene is fabZ

Identifier: 159184740

GI number: 159184740

Start: 1377948

End: 1378412

Strand: Direct

Name: fabZ

Synonym: Atu1383

Alternate gene names: 159184740

Gene position: 1377948-1378412 (Clockwise)

Preceding gene: 15888708

Following gene: 15888710

Centisome position: 48.49

GC content: 59.14

Gene sequence:

>465_bases
ATGGCTGACGAAACGAAGGCGACGCTTGGCACGGCCGACATCTTGGAAGTCATGAAACTTCTGCCGCATCGTTACCCGTT
TTTGCTCATCGACAAGATCATCGAGATCGATGGCGACAGTTCGGCGATCGGCATCAAGAACGTGACGGTCAACGAACCGC
ATTTCACCGGCCATTTCCCTGATCGGCCGATCATGCCGGGCGTTCTGATCGTCGAGGCGATGGCCCAGACGGCCGGCGCC
ATCTGCGCCCGTAACCAGGGCGAGGGCGGTCATCTCGTTTATTTCATGACCATCGACAACGCGCGTTTCCGCAGACCAGT
GGTTCCGGGCGATCGCCTCGAAATCCATGTGGTCAAGCAGCGCCAGCGCGGCAATGTGTTTAAGTTCCATTGCGAAGCGA
AGGTCGAAGGCGCGCTCGTGGCGGAAGCCGATGTCGGCGCGATGATGATCCCCGAGGGCCAGTAA

Upstream 100 bases:

>100_bases
GGCGGCATTCCGGCGCGTCCGATGAAACATTTCCTGCGCGATATGGCCGATATTCTGGCGCGCGCCGAAGAGCGTGATAA
AAAAACAGGAGAAAAAAACA

Downstream 100 bases:

>100_bases
TGAGCACGATCGCGGCTTCGGCGAAAATCCACCCGACTGCCGTTGTCGAGGATGGCGCAGTCATCGGTGAGAATGTCGTC
ATCGGTGCACTTGCCTATGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MADETKATLGTADILEVMKLLPHRYPFLLIDKIIEIDGDSSAIGIKNVTVNEPHFTGHFPDRPIMPGVLIVEAMAQTAGA
ICARNQGEGGHLVYFMTIDNARFRRPVVPGDRLEIHVVKQRQRGNVFKFHCEAKVEGALVAEADVGAMMIPEGQ

Sequences:

>Translated_154_residues
MADETKATLGTADILEVMKLLPHRYPFLLIDKIIEIDGDSSAIGIKNVTVNEPHFTGHFPDRPIMPGVLIVEAMAQTAGA
ICARNQGEGGHLVYFMTIDNARFRRPVVPGDRLEIHVVKQRQRGNVFKFHCEAKVEGALVAEADVGAMMIPEGQ
>Mature_153_residues
ADETKATLGTADILEVMKLLPHRYPFLLIDKIIEIDGDSSAIGIKNVTVNEPHFTGHFPDRPIMPGVLIVEAMAQTAGAI
CARNQGEGGHLVYFMTIDNARFRRPVVPGDRLEIHVVKQRQRGNVFKFHCEAKVEGALVAEADVGAMMIPEGQ

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=47.4452554744526, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_AGRT5 (Q8UFL4)

Other databases:

- EMBL:   AE007869
- PIR:   AG2746
- PIR:   F97527
- RefSeq:   NP_354390.2
- ProteinModelPortal:   Q8UFL4
- SMR:   Q8UFL4
- STRING:   Q8UFL4
- GeneID:   1133421
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1383
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q8UFL4
- ProtClustDB:   PRK00006
- BioCyc:   ATUM176299-1:ATU1383-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16904; Mature: 16773

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: ACT_SITE 58-58

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADETKATLGTADILEVMKLLPHRYPFLLIDKIIEIDGDSSAIGIKNVTVNEPHFTGHFP
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCC
DRPIMPGVLIVEAMAQTAGAICARNQGEGGHLVYFMTIDNARFRRPVVPGDRLEIHVVKQ
CCCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEE
RQRGNVFKFHCEAKVEGALVAEADVGAMMIPEGQ
CCCCCEEEEEEEEEECCEEEEECCCCEEEECCCC
>Mature Secondary Structure 
ADETKATLGTADILEVMKLLPHRYPFLLIDKIIEIDGDSSAIGIKNVTVNEPHFTGHFP
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCC
DRPIMPGVLIVEAMAQTAGAICARNQGEGGHLVYFMTIDNARFRRPVVPGDRLEIHVVKQ
CCCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEE
RQRGNVFKFHCEAKVEGALVAEADVGAMMIPEGQ
CCCCCEEEEEEEEEECCEEEEECCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194