Click here to switch to the map view.

The map label for this gene is aroQ

Identifier: 159184715

GI number: 159184715

Start: 1318720

End: 1319157

Strand: Reverse

Name: aroQ

Synonym: Atu1332

Alternate gene names: 159184715

Gene position: 1319157-1318720 (Counterclockwise)

Preceding gene: 159184716

Following gene: 15888656

Centisome position: 46.42

GC content: 55.94

Gene sequence:

>438_bases
ATGAGCAATATCATCATCGTCATCAACGGCCCCAATCTCAATATGCTGGGAAAACGGGAACCGGGTATCTACGGTGGCAA
AACGCTGAAAGACATAGAAAACGATTGTGTGAACGCCGGAGCCGATCTCGGCTTTTCGGTGGAATTTCGCCAATCCAACC
ACGAGGGCGTGCTCGTGGACTGGCTGCATGAGGCGGGCGAGCGGGCGGCGGGTGTCGTCATCAATCCCGGCGCTTACAGC
CACACCTCCATCGCCCTGCACGACGCCATTCGCGCAATTTCGACTCCGGTCGTGGAAGTGCACATCTCCAATATCCATGC
ACGGGAAGAATTCCGCCACAAATCAATGGTCTCGCCCGCAGCCAAGGGCATGATCTGCGGTTTCGGACCATATGGATACG
TCATGGCGCTTCACGCGCTGAAGAACATCACGGCATAA

Upstream 100 bases:

>100_bases
GTGAGATAAGGGGCAGCCCCTGCGCTTTACGGCTTGCAGGGGCTTTTCCTTGAAGGCTGCGCAGTCTATAGGTGTCGCTG
ATTTTCTTATGGAAACGCGA

Downstream 100 bases:

>100_bases
AAAGAAACAAAGAATAGGGTTTGTCATGTCTGAAAAGAAACAGGGTATCGACAAGGAACTGATCCGCGAACTCGCGAATA
TCCTCAATGATACCGACCTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase 1; Type II DHQase 1

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSNIIIVINGPNLNMLGKREPGIYGGKTLKDIENDCVNAGADLGFSVEFRQSNHEGVLVDWLHEAGERAAGVVINPGAYS
HTSIALHDAIRAISTPVVEVHISNIHAREEFRHKSMVSPAAKGMICGFGPYGYVMALHALKNITA

Sequences:

>Translated_145_residues
MSNIIIVINGPNLNMLGKREPGIYGGKTLKDIENDCVNAGADLGFSVEFRQSNHEGVLVDWLHEAGERAAGVVINPGAYS
HTSIALHDAIRAISTPVVEVHISNIHAREEFRHKSMVSPAAKGMICGFGPYGYVMALHALKNITA
>Mature_144_residues
SNIIIVINGPNLNMLGKREPGIYGGKTLKDIENDCVNAGADLGFSVEFRQSNHEGVLVDWLHEAGERAAGVVINPGAYSH
TSIALHDAIRAISTPVVEVHISNIHAREEFRHKSMVSPAAKGMICGFGPYGYVMALHALKNITA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ1_AGRT5 (Q8UFR5)

Other databases:

- EMBL:   AE007869
- PIR:   AD2740
- PIR:   B97521
- RefSeq:   NP_354338.2
- ProteinModelPortal:   Q8UFR5
- SMR:   Q8UFR5
- STRING:   Q8UFR5
- GeneID:   1133370
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1332
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BioCyc:   ATUM176299-1:ATU1332-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15603; Mature: 15472

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIIIVINGPNLNMLGKREPGIYGGKTLKDIENDCVNAGADLGFSVEFRQSNHEGVLVD
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEH
WLHEAGERAAGVVINPGAYSHTSIALHDAIRAISTPVVEVHISNIHAREEFRHKSMVSPA
HHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCC
AKGMICGFGPYGYVMALHALKNITA
CCCCEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNIIIVINGPNLNMLGKREPGIYGGKTLKDIENDCVNAGADLGFSVEFRQSNHEGVLVD
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEH
WLHEAGERAAGVVINPGAYSHTSIALHDAIRAISTPVVEVHISNIHAREEFRHKSMVSPA
HHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCC
AKGMICGFGPYGYVMALHALKNITA
CCCCEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194