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The map label for this gene is dinP

Identifier: 159184698

GI number: 159184698

Start: 1284614

End: 1285831

Strand: Reverse

Name: dinP

Synonym: Atu1294

Alternate gene names: 159184698

Gene position: 1285831-1284614 (Counterclockwise)

Preceding gene: 15888622

Following gene: 159184697

Centisome position: 45.25

GC content: 60.18

Gene sequence:

>1218_bases
TTGAGGCGTTGCCGCGCCTGTGGCAGCCCGCGTCTTCTCTATCATTCCGAACTCTACGATCTGAGCATCGCCCATATCGA
TTGCGATGCCTTTTATGCCTCTGTCGAAAAGCGCGACAATCCGGAACTGGCCGATAAACCTGTGATCGTTGGCGGCGGCA
AGCGCGGGGTGGTTTCCACCGCCTGTTATATCGCCCGCATCCACGGCGTGCGCTCCGCCATGCCCATGTTCAAGGCACTG
GAAGCCTGCCCGGATGCGGTCGTCATCAAGCCGGATATGGAAAAATACAGTCGTGTCGGCCGTGAAATCCGGACCATGAT
GCAGGAATTGACGCCGCTAGTGCAGCCGCTTTCCATCGACGAGGCGTTTCTCGATCTTTCAGGTACCGAGAAGCTGCATC
ACGATCCGCCGGCGCGGGTGCTGGCGAAGTTCACCGGACGCGTTGAAAAAGAGGTGGGGGTGAGTGTTTCGGCAGGGCTT
TCCTATTGCAAGTTTCTCGCCAAGGTCGCGTCGGACCTGCAAAAGCCACGCGGCTTTTCTGTTGTCGGCGAAGCGGAGGC
GCTGTCCTTTCTGGCAGCGCGCCCGGTCACGACGATCTGGGGCGTGGGAAAGGCCTTTGCAGCGACGCTGGAGGCGGATG
GCATCCGCATGATCGCGCAATTGCAGGAGATGGAGGAGAGCGAGCTGATGCGCCGTTACGGCGTGATGGGGCAGCGGCTG
TTCCGGCTCGCACGCGGCATTGACGAGCGGCATGTGCATAATAACGATCCGGTCAAAAGCGTATCGTCCGAAACCACCTT
CTTCCACGATATTTCCCGCCATGAGGACCTCGTTCCAATCCTGCGGTCACTCTCCGAAAAAGTTGCCTGGCGGTTAAAGA
AAAGCGGTATTGCCGGCCAGACCGTGGTGCTGAAGATGAAAACGGCGGACTTCAAGAGCCGCACCCGCAACCGCAGGCTT
GATGACCCCACTCAGCTTGCCGACCGCATATTCCGCACCGGCCTTGCCCTGCTGGAAAAAGAAACCGACGGCACGAAATT
CCGCCTCATCGGCATCGGCGTCAGCGATCTGCGCGATGCCGGTCTTGCCGATCCGCCCGATCTCGTTGACAGACAGGCCA
CGCGGCGGGCCGCGGCGGAGGCGGCAATGGACAAGCTGCGCGATAAGTTCGGCAAGGGCAGCGTCGAGACTGGCTACACC
TTCCGCACCCGCAAATAG

Upstream 100 bases:

>100_bases
ATGGTTGGCTACGTTCTGGTTTTGTTTTCGACCCATGTCCACGTCGCACCGCTATGATCCCGGTTTTTGCCGCGACTGCC
TGGCTGGCCAGCCAGAAGGG

Downstream 100 bases:

>100_bases
AGAACTGAAGGCGACCATGCGGACCTTCCCACCAACGTGCGCAATGTATTTTAGATTTTACACAAATTAGTGATGTTGCC
GTCGCCGCTTCCTTAAACTT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRRCRACGSPRLLYHSELYDLSIAHIDCDAFYASVEKRDNPELADKPVIVGGGKRGVVSTACYIARIHGVRSAMPMFKAL
EACPDAVVIKPDMEKYSRVGREIRTMMQELTPLVQPLSIDEAFLDLSGTEKLHHDPPARVLAKFTGRVEKEVGVSVSAGL
SYCKFLAKVASDLQKPRGFSVVGEAEALSFLAARPVTTIWGVGKAFAATLEADGIRMIAQLQEMEESELMRRYGVMGQRL
FRLARGIDERHVHNNDPVKSVSSETTFFHDISRHEDLVPILRSLSEKVAWRLKKSGIAGQTVVLKMKTADFKSRTRNRRL
DDPTQLADRIFRTGLALLEKETDGTKFRLIGIGVSDLRDAGLADPPDLVDRQATRRAAAEAAMDKLRDKFGKGSVETGYT
FRTRK

Sequences:

>Translated_405_residues
MRRCRACGSPRLLYHSELYDLSIAHIDCDAFYASVEKRDNPELADKPVIVGGGKRGVVSTACYIARIHGVRSAMPMFKAL
EACPDAVVIKPDMEKYSRVGREIRTMMQELTPLVQPLSIDEAFLDLSGTEKLHHDPPARVLAKFTGRVEKEVGVSVSAGL
SYCKFLAKVASDLQKPRGFSVVGEAEALSFLAARPVTTIWGVGKAFAATLEADGIRMIAQLQEMEESELMRRYGVMGQRL
FRLARGIDERHVHNNDPVKSVSSETTFFHDISRHEDLVPILRSLSEKVAWRLKKSGIAGQTVVLKMKTADFKSRTRNRRL
DDPTQLADRIFRTGLALLEKETDGTKFRLIGIGVSDLRDAGLADPPDLVDRQATRRAAAEAAMDKLRDKFGKGSVETGYT
FRTRK
>Mature_405_residues
MRRCRACGSPRLLYHSELYDLSIAHIDCDAFYASVEKRDNPELADKPVIVGGGKRGVVSTACYIARIHGVRSAMPMFKAL
EACPDAVVIKPDMEKYSRVGREIRTMMQELTPLVQPLSIDEAFLDLSGTEKLHHDPPARVLAKFTGRVEKEVGVSVSAGL
SYCKFLAKVASDLQKPRGFSVVGEAEALSFLAARPVTTIWGVGKAFAATLEADGIRMIAQLQEMEESELMRRYGVMGQRL
FRLARGIDERHVHNNDPVKSVSSETTFFHDISRHEDLVPILRSLSEKVAWRLKKSGIAGQTVVLKMKTADFKSRTRNRRL
DDPTQLADRIFRTGLALLEKETDGTKFRLIGIGVSDLRDAGLADPPDLVDRQATRRAAAEAAMDKLRDKFGKGSVETGYT
FRTRK

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=422, Percent_Identity=23.696682464455, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI7706681, Length=423, Percent_Identity=23.6406619385343, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI7705344, Length=106, Percent_Identity=45.2830188679245, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI154350220, Length=281, Percent_Identity=28.1138790035587, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1786425, Length=345, Percent_Identity=37.3913043478261, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787432, Length=390, Percent_Identity=24.6153846153846, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=397, Percent_Identity=30.4785894206549, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17537959, Length=303, Percent_Identity=25.0825082508251, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193205702, Length=220, Percent_Identity=31.8181818181818, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=347, Percent_Identity=25.9365994236311, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355641, Length=362, Percent_Identity=23.7569060773481, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644984, Length=362, Percent_Identity=23.7569060773481, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24668444, Length=130, Percent_Identity=32.3076923076923, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO41_AGRT5 (Q8UFV3)

Other databases:

- EMBL:   AE007869
- PIR:   AF2735
- PIR:   F97516
- RefSeq:   NP_354302.2
- ProteinModelPortal:   Q8UFV3
- SMR:   Q8UFV3
- STRING:   Q8UFV3
- GeneID:   1133332
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1294
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   ACYIARI
- PhylomeDB:   Q8UFV3
- ProtClustDB:   PRK02794
- BioCyc:   ATUM176299-1:ATU1294-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 45037; Mature: 45037

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 121-121

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRCRACGSPRLLYHSELYDLSIAHIDCDAFYASVEKRDNPELADKPVIVGGGKRGVVST
CCCCCCCCCCCEEEECHHHEEEEEEEEHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHH
ACYIARIHGVRSAMPMFKALEACPDAVVIKPDMEKYSRVGREIRTMMQELTPLVQPLSID
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAFLDLSGTEKLHHDPPARVLAKFTGRVEKEVGVSVSAGLSYCKFLAKVASDLQKPRGFS
HHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCE
VVGEAEALSFLAARPVTTIWGVGKAFAATLEADGIRMIAQLQEMEESELMRRYGVMGQRL
EECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLARGIDERHVHNNDPVKSVSSETTFFHDISRHEDLVPILRSLSEKVAWRLKKSGIAGQ
HHHHCCCCHHCCCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
TVVLKMKTADFKSRTRNRRLDDPTQLADRIFRTGLALLEKETDGTKFRLIGIGVSDLRDA
EEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHC
GLADPPDLVDRQATRRAAAEAAMDKLRDKFGKGSVETGYTFRTRK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCC
>Mature Secondary Structure
MRRCRACGSPRLLYHSELYDLSIAHIDCDAFYASVEKRDNPELADKPVIVGGGKRGVVST
CCCCCCCCCCCEEEECHHHEEEEEEEEHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHH
ACYIARIHGVRSAMPMFKALEACPDAVVIKPDMEKYSRVGREIRTMMQELTPLVQPLSID
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAFLDLSGTEKLHHDPPARVLAKFTGRVEKEVGVSVSAGLSYCKFLAKVASDLQKPRGFS
HHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCE
VVGEAEALSFLAARPVTTIWGVGKAFAATLEADGIRMIAQLQEMEESELMRRYGVMGQRL
EECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLARGIDERHVHNNDPVKSVSSETTFFHDISRHEDLVPILRSLSEKVAWRLKKSGIAGQ
HHHHCCCCHHCCCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
TVVLKMKTADFKSRTRNRRLDDPTQLADRIFRTGLALLEKETDGTKFRLIGIGVSDLRDA
EEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHC
GLADPPDLVDRQATRRAAAEAAMDKLRDKFGKGSVETGYTFRTRK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194