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The map label for this gene is trkH [H]

Identifier: 159184663

GI number: 159184663

Start: 1197074

End: 1198411

Strand: Reverse

Name: trkH [H]

Synonym: Atu1204

Alternate gene names: 159184663

Gene position: 1198411-1197074 (Counterclockwise)

Preceding gene: 159184667

Following gene: 15888539

Centisome position: 42.17

GC content: 60.16

Gene sequence:

>1338_bases
GTGTTTGCGCTTTCGGGTTTCATGTGCGGCGGCTTCTCGCTGGCCTGCGCGCTCGCCACCCGCGGCCCTATCACCTCCTT
CAACAAACGTTTCGGCTTCCTGCTCGTCAACCTGCTGTGGCTGGTGTTTTCCATCGTCGGCGCGGTGCCGCTTTACCTGT
CCGAACTTGGTCTGACGCCCGGTCAAGCGCTCTTTGAATCCGTTTCCGCCATCACCACGACAGGATCGACCGCCATATCC
GGGCTAGACCACGCGCCGCAGGGCATTCTCCTCTGGCGGTCGCTGCTCTGCTGGCTCGGCGGCATCGGTATCGTCGCACT
CGGTCTCTTCATCCTGCCGTTGCTGCGCGTGGGCGGCATGACCTTCTTTCGCATGGAGTCTTCCGATACCGGCAACGACC
GGCCCTTCGCGCGGCTGGCAAGCTTTACACGGGCTTTCGTGGCGATCTACATCATCATGACGCTCGCCTGCACCATGGCC
TATGACTTTGCCGGCATGTCACATTTCGATGCGCTGAACCATGCCATGTCGACGGTCGCGACCGGTGGGTTTTCCACCCA
CGACGCCTCCTTTGCCTATTTCAACAATACCGCCCTGCTGTGGATTGCCACCATCTTCCTGATCTTCGGCAGCCTGCCCT
TCTCAGTCATGATCCTGCTTGCGGTGCGCCGCCGGCTGGAGACGCTGCGTGACCCGCAGATCGCCGTCTTCCTTGGTTAT
CTCTGCGCGATCTCGATTGCGGTCGGCGTTTATCATCATTTCAGGAACGGCGTGCCGCTGGACGATGCGCTCAGCCATTC
CTTCTTCAACATGACCTCGATCCTCTCGACCGGCGGTTTTGCGAGCGATGACTATACGCTCTGGGGGCCCTTCGTCGTTG
TCGTCGCCTTTTTCGCGACGTTCATGGGCGGCTGTTCCGGCTCGACGGCGGGCGGCATCAAGGCCTATCGTTTTCTCATC
ATGTTCAACGTGGTGCGGGCCGGCCTCAAAAAACTGATCTATCCGAACGCCGTCTATTCCGTGCGTTATGGCCAGCAGGT
GGTCGATCCGGACACGATCCGTACGATCTTCCTTTTTGTCAGTTGTTTTATCGCCCTGTGGATCGCCGGTAGCCTTGCCA
TGAGCCTGATGGGTTATGATTTCCTCACCGCCACCTCGGCCGTTGCGACCTCGCTTGCCAATGTCGGCCCGGGTATCGGC
CCCATCATCGGCCCGGCCGGCAATTTCTCCACCATCAGCGAACCGGCGCTCTATCTCCTGTCCGTCCTGATGCTGCTCGG
GCGCCTGGAAATCCTGACGGTGCTCGTGCTGCTGATGCCGATTTTCTGGCGCAGCTGA

Upstream 100 bases:

>100_bases
CTCCGTCATCTATGTGGCGTCCATCTTCGGGCTCTACCTTGCAACGGCCATGTTCCTGCCGGCGCTGACCGATCTTTATT
ACGGCAATGACGACTGGATG

Downstream 100 bases:

>100_bases
TCCGGCGAAACAGATGTTGCGCAGGGGCGAATAAAGCGCTTGACCTTCCCACGTTGGAATAGTTCAGGCTCCACCTGTTA
TAATTCCAAACCATGGAGAA

Product: potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MFALSGFMCGGFSLACALATRGPITSFNKRFGFLLVNLLWLVFSIVGAVPLYLSELGLTPGQALFESVSAITTTGSTAIS
GLDHAPQGILLWRSLLCWLGGIGIVALGLFILPLLRVGGMTFFRMESSDTGNDRPFARLASFTRAFVAIYIIMTLACTMA
YDFAGMSHFDALNHAMSTVATGGFSTHDASFAYFNNTALLWIATIFLIFGSLPFSVMILLAVRRRLETLRDPQIAVFLGY
LCAISIAVGVYHHFRNGVPLDDALSHSFFNMTSILSTGGFASDDYTLWGPFVVVVAFFATFMGGCSGSTAGGIKAYRFLI
MFNVVRAGLKKLIYPNAVYSVRYGQQVVDPDTIRTIFLFVSCFIALWIAGSLAMSLMGYDFLTATSAVATSLANVGPGIG
PIIGPAGNFSTISEPALYLLSVLMLLGRLEILTVLVLLMPIFWRS

Sequences:

>Translated_445_residues
MFALSGFMCGGFSLACALATRGPITSFNKRFGFLLVNLLWLVFSIVGAVPLYLSELGLTPGQALFESVSAITTTGSTAIS
GLDHAPQGILLWRSLLCWLGGIGIVALGLFILPLLRVGGMTFFRMESSDTGNDRPFARLASFTRAFVAIYIIMTLACTMA
YDFAGMSHFDALNHAMSTVATGGFSTHDASFAYFNNTALLWIATIFLIFGSLPFSVMILLAVRRRLETLRDPQIAVFLGY
LCAISIAVGVYHHFRNGVPLDDALSHSFFNMTSILSTGGFASDDYTLWGPFVVVVAFFATFMGGCSGSTAGGIKAYRFLI
MFNVVRAGLKKLIYPNAVYSVRYGQQVVDPDTIRTIFLFVSCFIALWIAGSLAMSLMGYDFLTATSAVATSLANVGPGIG
PIIGPAGNFSTISEPALYLLSVLMLLGRLEILTVLVLLMPIFWRS
>Mature_445_residues
MFALSGFMCGGFSLACALATRGPITSFNKRFGFLLVNLLWLVFSIVGAVPLYLSELGLTPGQALFESVSAITTTGSTAIS
GLDHAPQGILLWRSLLCWLGGIGIVALGLFILPLLRVGGMTFFRMESSDTGNDRPFARLASFTRAFVAIYIIMTLACTMA
YDFAGMSHFDALNHAMSTVATGGFSTHDASFAYFNNTALLWIATIFLIFGSLPFSVMILLAVRRRLETLRDPQIAVFLGY
LCAISIAVGVYHHFRNGVPLDDALSHSFFNMTSILSTGGFASDDYTLWGPFVVVVAFFATFMGGCSGSTAGGIKAYRFLI
MFNVVRAGLKKLIYPNAVYSVRYGQQVVDPDTIRTIFLFVSCFIALWIAGSLAMSLMGYDFLTATSAVATSLANVGPGIG
PIIGPAGNFSTISEPALYLLSVLMLLGRLEILTVLVLLMPIFWRS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=431, Percent_Identity=36.4269141531323, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI48994987, Length=434, Percent_Identity=38.2488479262673, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 47995; Mature: 47995

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALSGFMCGGFSLACALATRGPITSFNKRFGFLLVNLLWLVFSIVGAVPLYLSELGLTP
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GQALFESVSAITTTGSTAISGLDHAPQGILLWRSLLCWLGGIGIVALGLFILPLLRVGGM
HHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
TFFRMESSDTGNDRPFARLASFTRAFVAIYIIMTLACTMAYDFAGMSHFDALNHAMSTVA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TGGFSTHDASFAYFNNTALLWIATIFLIFGSLPFSVMILLAVRRRLETLRDPQIAVFLGY
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LCAISIAVGVYHHFRNGVPLDDALSHSFFNMTSILSTGGFASDDYTLWGPFVVVVAFFAT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
FMGGCSGSTAGGIKAYRFLIMFNVVRAGLKKLIYPNAVYSVRYGQQVVDPDTIRTIFLFV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHHHHHHHHHH
SCFIALWIAGSLAMSLMGYDFLTATSAVATSLANVGPGIGPIIGPAGNFSTISEPALYLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
SVLMLLGRLEILTVLVLLMPIFWRS
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFALSGFMCGGFSLACALATRGPITSFNKRFGFLLVNLLWLVFSIVGAVPLYLSELGLTP
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GQALFESVSAITTTGSTAISGLDHAPQGILLWRSLLCWLGGIGIVALGLFILPLLRVGGM
HHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
TFFRMESSDTGNDRPFARLASFTRAFVAIYIIMTLACTMAYDFAGMSHFDALNHAMSTVA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TGGFSTHDASFAYFNNTALLWIATIFLIFGSLPFSVMILLAVRRRLETLRDPQIAVFLGY
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LCAISIAVGVYHHFRNGVPLDDALSHSFFNMTSILSTGGFASDDYTLWGPFVVVVAFFAT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
FMGGCSGSTAGGIKAYRFLIMFNVVRAGLKKLIYPNAVYSVRYGQQVVDPDTIRTIFLFV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHHHHHHHHHH
SCFIALWIAGSLAMSLMGYDFLTATSAVATSLANVGPGIGPIIGPAGNFSTISEPALYLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
SVLMLLGRLEILTVLVLLMPIFWRS
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]