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The map label for this gene is betI

Identifier: 159184483

GI number: 159184483

Start: 826620

End: 827240

Strand: Direct

Name: betI

Synonym: Atu0828

Alternate gene names: 159184483

Gene position: 826620-827240 (Clockwise)

Preceding gene: 159184480

Following gene: 15888169

Centisome position: 29.09

GC content: 62.64

Gene sequence:

>621_bases
ATGCCCAAGATCGGAATGGAGCCTTTGCGCCGCAAGGCGCTTGTGGATGCGGCGTTGCGCACCATAGGCCACCATGGTTC
ACTGAATGTGACAATGTCTGATATCGCCCGGGAAGCGGGCGTGTCGGCAGCGCTTGCGCATCATTATTTCGGCAGCAAGC
AGCAGCTGCTTCTGGAAACCATCCGCAGCCTGCTGCGTGATCTGAGGCGCGATGCCGTGGCGGCACTGATCCGTGCCTCC
GGTCCGCGTGAAAAGCTGAGCGCCATCGTGCACGTCTCCTTCCAGAGCGACCAGTTCACGCCCGAAACGGTAGCGGCCTG
GCTTGCCTTTTACGTCGAGGCGCAGCGCTCGGAAGAAACGCGCCGCCTGCTGGTCATTTATTCCCGCCGCCTGCGCTCCA
ATCTCATGGCGAGCCTCAACCGGCTTTGCCCACCCGACGATGCCGCGCGCATCGCCGAAGGGGCAGCCGCCCTGATCGAC
GGGCTTTATATCCGCCACAGCCTGCGTTCCGCCCCGCTTGGCCTCGCTTCCGCGCCGGCGCTTGTCGAGGATTATTTCGA
CATGCAGCTCAAATCTTTTCCCGATGGACAGCGCGCCAAGCCGTCCATCCGCACTCTCTAG

Upstream 100 bases:

>100_bases
GAAAATATGATCCATCGCAAATCCGCGACATAAAATGGCGCATTTTTTATTGATTGATCACTCAATCAAGAATAATTTGC
CGTCCGTCAAGGAGACGCTT

Downstream 100 bases:

>100_bases
GAGACTTCGACATGACCATTGCGACGCCGCTCAAGGCGCAGCCGAAAGCCTCGCATTTCATCGACGGGGATTATGTCGAG
GACAATACCGGCACGCCGTT

Product: transcriptional regulator BetI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MPKIGMEPLRRKALVDAALRTIGHHGSLNVTMSDIAREAGVSAALAHHYFGSKQQLLLETIRSLLRDLRRDAVAALIRAS
GPREKLSAIVHVSFQSDQFTPETVAAWLAFYVEAQRSEETRRLLVIYSRRLRSNLMASLNRLCPPDDAARIAEGAAALID
GLYIRHSLRSAPLGLASAPALVEDYFDMQLKSFPDGQRAKPSIRTL

Sequences:

>Translated_206_residues
MPKIGMEPLRRKALVDAALRTIGHHGSLNVTMSDIAREAGVSAALAHHYFGSKQQLLLETIRSLLRDLRRDAVAALIRAS
GPREKLSAIVHVSFQSDQFTPETVAAWLAFYVEAQRSEETRRLLVIYSRRLRSNLMASLNRLCPPDDAARIAEGAAALID
GLYIRHSLRSAPLGLASAPALVEDYFDMQLKSFPDGQRAKPSIRTL
>Mature_205_residues
PKIGMEPLRRKALVDAALRTIGHHGSLNVTMSDIAREAGVSAALAHHYFGSKQQLLLETIRSLLRDLRRDAVAALIRASG
PREKLSAIVHVSFQSDQFTPETVAAWLAFYVEAQRSEETRRLLVIYSRRLRSNLMASLNRLCPPDDAARIAEGAAALIDG
LYIRHSLRSAPLGLASAPALVEDYFDMQLKSFPDGQRAKPSIRTL

Specific function: Repressor involved in choline regulation of the bet genes

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1786505, Length=193, Percent_Identity=37.8238341968912, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BETI_AGRT5 (Q8UH57)

Other databases:

- EMBL:   AE007869
- PIR:   A97460
- PIR:   AD2678
- RefSeq:   NP_353849.2
- ProteinModelPortal:   Q8UH57
- SMR:   Q8UH57
- STRING:   Q8UH57
- GeneID:   1132866
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0828
- eggNOG:   COG1309
- HOGENOM:   HBG684746
- OMA:   MINEEAT
- PhylomeDB:   Q8UH57
- ProtClustDB:   PRK00767
- BioCyc:   ATUM176299-1:ATU0828-MONOMER
- HAMAP:   MF_00768
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR017757
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455
- TIGRFAMs:   TIGR03384

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 22770; Mature: 22638

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIGMEPLRRKALVDAALRTIGHHGSLNVTMSDIAREAGVSAALAHHYFGSKQQLLLET
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IRSLLRDLRRDAVAALIRASGPREKLSAIVHVSFQSDQFTPETVAAWLAFYVEAQRSEET
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RRLLVIYSRRLRSNLMASLNRLCPPDDAARIAEGAAALIDGLYIRHSLRSAPLGLASAPA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LVEDYFDMQLKSFPDGQRAKPSIRTL
HHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PKIGMEPLRRKALVDAALRTIGHHGSLNVTMSDIAREAGVSAALAHHYFGSKQQLLLET
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IRSLLRDLRRDAVAALIRASGPREKLSAIVHVSFQSDQFTPETVAAWLAFYVEAQRSEET
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RRLLVIYSRRLRSNLMASLNRLCPPDDAARIAEGAAALIDGLYIRHSLRSAPLGLASAPA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LVEDYFDMQLKSFPDGQRAKPSIRTL
HHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194