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The map label for this gene is coxB [H]

Identifier: 159184457

GI number: 159184457

Start: 762636

End: 763499

Strand: Direct

Name: coxB [H]

Synonym: Atu0767

Alternate gene names: 159184457

Gene position: 762636-763499 (Clockwise)

Preceding gene: 15888105

Following gene: 159184458

Centisome position: 26.84

GC content: 60.76

Gene sequence:

>864_bases
ATGACCTGTCTGCTCACGGCTGTCGGCGCCCACGCCGATCAGCCGGTGCATTGGCAAATGGGCATGCAGGAGGCCGCCAC
GCCGATCATGCACGAAATACGCTGGTTCGAACAATATACACTGTGGTTCATTGTTCCGGTCACGCTTTTCGTTCTTGCGC
TGCTCATCATCGTTGCCGTCAAGTTCCACGCCGCGAAAAATCCGGTGGCTTCCAAGACCAGCCATAACACGGCGATCGAG
GTGGTGTGGACGCTGGCGCCGGTGCTCATTCTCCTGTTCCTCGCTTTCCCCTCGTTCAATCTTCTGAACGCGCAGCTGAC
GCAGCCGGAAAACCCGGACCTGACGCTGAAGGCGACCGCCACGCAGTGGCTGTGGAGCTATGAATACAAGGCCGCCGAGG
GCGCAGAGCCGCTCTCCTTCGACAGCTACCTGCTGAAGGATCAGGATCGCGCCGCTGCCGGCAAGGAAGACAAGGCCCGC
TATCCGCGCCTTCTCGCGGTCGACAATGAAATGGTTGTTCCCGTCGGCAAGACAGTTCGCCTTCTGGTGACGGCGGCTCC
GACGGATGTCATCCACGCCTTCGCCATGCCCGCCTTCGGCGTCAAGATCGATGCCGTTCCGGGCCGCCTCAATGAAACAT
GGTTCAAGCCGGAGAAGGAAGGCCTGTATTACGGCCAATGTTCCGAGCTTTGCGGCAAGGACCACGCTTTCATGCCGATC
GCCATTCGGGTGGTTTCCGAACAGCAGTACAACACCTGGCACGCCGCCGCCGCTTCAGATCTGAACGGCGCGAACCGGGC
GTTGATGGCCTCCGTCGATGGCGCTCCGCGCACGGTCGACGTTGCCGCCAACGAAACCAACTGA

Upstream 100 bases:

>100_bases
TAGTACCATAAGCATGGATTCTGCGTCTGTGATTGATCTAGATCAGACGCGTGAGGGAGAGGGTACCGTGACGAATAGGA
TTTACGCAGCACTGGCGGGG

Downstream 100 bases:

>100_bases
GACCTGGAGTGACGACAATGGCTGGACCTTCCGCACACGACGATCATCACTCGCATGGTCAATCCGCACATGACGCGCAT
GCGCATGACGATCATTCGCA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTCLLTAVGAHADQPVHWQMGMQEAATPIMHEIRWFEQYTLWFIVPVTLFVLALLIIVAVKFHAAKNPVASKTSHNTAIE
VVWTLAPVLILLFLAFPSFNLLNAQLTQPENPDLTLKATATQWLWSYEYKAAEGAEPLSFDSYLLKDQDRAAAGKEDKAR
YPRLLAVDNEMVVPVGKTVRLLVTAAPTDVIHAFAMPAFGVKIDAVPGRLNETWFKPEKEGLYYGQCSELCGKDHAFMPI
AIRVVSEQQYNTWHAAAASDLNGANRALMASVDGAPRTVDVAANETN

Sequences:

>Translated_287_residues
MTCLLTAVGAHADQPVHWQMGMQEAATPIMHEIRWFEQYTLWFIVPVTLFVLALLIIVAVKFHAAKNPVASKTSHNTAIE
VVWTLAPVLILLFLAFPSFNLLNAQLTQPENPDLTLKATATQWLWSYEYKAAEGAEPLSFDSYLLKDQDRAAAGKEDKAR
YPRLLAVDNEMVVPVGKTVRLLVTAAPTDVIHAFAMPAFGVKIDAVPGRLNETWFKPEKEGLYYGQCSELCGKDHAFMPI
AIRVVSEQQYNTWHAAAASDLNGANRALMASVDGAPRTVDVAANETN
>Mature_286_residues
TCLLTAVGAHADQPVHWQMGMQEAATPIMHEIRWFEQYTLWFIVPVTLFVLALLIIVAVKFHAAKNPVASKTSHNTAIEV
VWTLAPVLILLFLAFPSFNLLNAQLTQPENPDLTLKATATQWLWSYEYKAAEGAEPLSFDSYLLKDQDRAAAGKEDKARY
PRLLAVDNEMVVPVGKTVRLLVTAAPTDVIHAFAMPAFGVKIDAVPGRLNETWFKPEKEGLYYGQCSELCGKDHAFMPIA
IRVVSEQQYNTWHAAAASDLNGANRALMASVDGAPRTVDVAANETN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=227, Percent_Identity=36.5638766519824, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6226540, Length=244, Percent_Identity=38.9344262295082, Blast_Score=166, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31679; Mature: 31548

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCLLTAVGAHADQPVHWQMGMQEAATPIMHEIRWFEQYTLWFIVPVTLFVLALLIIVAV
CEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFHAAKNPVASKTSHNTAIEVVWTLAPVLILLFLAFPSFNLLNAQLTQPENPDLTLKATA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEH
TQWLWSYEYKAAEGAEPLSFDSYLLKDQDRAAAGKEDKARYPRLLAVDNEMVVPVGKTVR
HHHEEEEEECCCCCCCCCCCCHHHHCCCCHHCCCCCCHHHCCEEEEECCCEEEECCCEEE
LLVTAAPTDVIHAFAMPAFGVKIDAVPGRLNETWFKPEKEGLYYGQCSELCGKDHAFMPI
EEEEECCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHCCCCCCEEEE
AIRVVSEQQYNTWHAAAASDLNGANRALMASVDGAPRTVDVAANETN
EEEEECCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCEEEEECCCCC
>Mature Secondary Structure 
TCLLTAVGAHADQPVHWQMGMQEAATPIMHEIRWFEQYTLWFIVPVTLFVLALLIIVAV
EEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFHAAKNPVASKTSHNTAIEVVWTLAPVLILLFLAFPSFNLLNAQLTQPENPDLTLKATA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEH
TQWLWSYEYKAAEGAEPLSFDSYLLKDQDRAAAGKEDKARYPRLLAVDNEMVVPVGKTVR
HHHEEEEEECCCCCCCCCCCCHHHHCCCCHHCCCCCCHHHCCEEEEECCCEEEECCCEEE
LLVTAAPTDVIHAFAMPAFGVKIDAVPGRLNETWFKPEKEGLYYGQCSELCGKDHAFMPI
EEEEECCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHCCCCCCEEEE
AIRVVSEQQYNTWHAAAASDLNGANRALMASVDGAPRTVDVAANETN
EEEEECCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA