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The map label for this gene is ttdR [H]

Identifier: 159184411

GI number: 159184411

Start: 659193

End: 660092

Strand: Reverse

Name: ttdR [H]

Synonym: Atu0664

Alternate gene names: 159184411

Gene position: 660092-659193 (Counterclockwise)

Preceding gene: 15888010

Following gene: 15888004

Centisome position: 23.23

GC content: 61.11

Gene sequence:

>900_bases
ATGGCAAATCTGGGTGATCTGGAAGTCTTCGCAAGCGTTGCCGCCTCCGGCAGCATGTCGCTGGCCGCCAAGGAGCTTGG
CTATTCGCCCGCCGTGATTTCCAAACGCATCAAGCGGCTGGAAGAAAAGCTCGGCGCACGGCTTTTCCAGCGCACAACGC
GGCAAATCTCTTTGACCGAAGCCGGGCAGGGATTTTACGAGCGGGTGCTGGCCGTGCTGGCGGGGCTTGAAGAAGCCGAG
GACTTTGTGTCCGGCCGGGCCAACACCGTCAACGGCACGCTGAAGGTTTCCGCCCCCACCTCCTTCGGGCGCATGCATAT
CGCGCCACATCTGAAGGGTTTCATGGAGCGGCATCCTGACCTCTCGGTCAATCTGGTGCTCAGCGACGAGTTCATCGATA
TTATCGAAGGCGGTTACGATCTGGCGATCCGCATTGCCGATCTCAATTCCTCAAGCCTCGTCGCCCGCAGGCTGGCGCCG
GTGCGGCGTGTGCTCTGCGCCTCGGCTGATTATGTTGTCGCGCACGGTATGCCCGCGACAATCGAGGATCTGAAGAAACA
CCGCTGCCTGCCGGCGCACAATAATGACATCTGGCGACTGGAGGGACCGGGCGGCGCGCTCAGCATTCGCCCGGAGGGCA
TGCTGGTCACCAATTCGAGCGAGGTGATCCGCGAGGCGGTGATATCAGGGCTTGGTATCGCGCTGCGTTCGACATGGGAT
ATCGGCCATGAATTGCGCAGCGGGAAACTGGTACAGGTGCTGCCCGGTTATGAGGGGTCGCGCAACGTGACGCTGTCTGC
GGTCTATCCGAGCCGGCAGTTCCTGCCTGCCAAGGTGCGGTTGTTCATCGATTATCTCGCCGGGCTTTATGGGCCGTCGC
CCTACTGGGAACAGGGCTAA

Upstream 100 bases:

>100_bases
CATGCACGTTCCTCCAACTGGTATTCTTTCTTTACCACTTTGAAACGGCGCAATCAAATGTTATGGATTTTTTCCATTCT
GGAAATAATCGGAGGCAACT

Downstream 100 bases:

>100_bases
GGCGGTTAAGTCGCGCCGTCACCACCAATCTTCCCTCATCCCTGTGCTCGTCACAGGGATCCAGCCAGCCCAAGTCCTTG
GGCTGAAAAGAGTCTTCCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MANLGDLEVFASVAASGSMSLAAKELGYSPAVISKRIKRLEEKLGARLFQRTTRQISLTEAGQGFYERVLAVLAGLEEAE
DFVSGRANTVNGTLKVSAPTSFGRMHIAPHLKGFMERHPDLSVNLVLSDEFIDIIEGGYDLAIRIADLNSSSLVARRLAP
VRRVLCASADYVVAHGMPATIEDLKKHRCLPAHNNDIWRLEGPGGALSIRPEGMLVTNSSEVIREAVISGLGIALRSTWD
IGHELRSGKLVQVLPGYEGSRNVTLSAVYPSRQFLPAKVRLFIDYLAGLYGPSPYWEQG

Sequences:

>Translated_299_residues
MANLGDLEVFASVAASGSMSLAAKELGYSPAVISKRIKRLEEKLGARLFQRTTRQISLTEAGQGFYERVLAVLAGLEEAE
DFVSGRANTVNGTLKVSAPTSFGRMHIAPHLKGFMERHPDLSVNLVLSDEFIDIIEGGYDLAIRIADLNSSSLVARRLAP
VRRVLCASADYVVAHGMPATIEDLKKHRCLPAHNNDIWRLEGPGGALSIRPEGMLVTNSSEVIREAVISGLGIALRSTWD
IGHELRSGKLVQVLPGYEGSRNVTLSAVYPSRQFLPAKVRLFIDYLAGLYGPSPYWEQG
>Mature_298_residues
ANLGDLEVFASVAASGSMSLAAKELGYSPAVISKRIKRLEEKLGARLFQRTTRQISLTEAGQGFYERVLAVLAGLEEAED
FVSGRANTVNGTLKVSAPTSFGRMHIAPHLKGFMERHPDLSVNLVLSDEFIDIIEGGYDLAIRIADLNSSSLVARRLAPV
RRVLCASADYVVAHGMPATIEDLKKHRCLPAHNNDIWRLEGPGGALSIRPEGMLVTNSSEVIREAVISGLGIALRSTWDI
GHELRSGKLVQVLPGYEGSRNVTLSAVYPSRQFLPAKVRLFIDYLAGLYGPSPYWEQG

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=36.5853658536585, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=37.3287671232877, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=38.2252559726962, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=31.4878892733564, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=31.0580204778157, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=26.9360269360269, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788706, Length=298, Percent_Identity=25.8389261744966, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789173, Length=249, Percent_Identity=28.9156626506024, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790011, Length=293, Percent_Identity=24.5733788395904, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786448, Length=298, Percent_Identity=27.1812080536913, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=297, Percent_Identity=27.6094276094276, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790208, Length=144, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI157672245, Length=177, Percent_Identity=29.9435028248588, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32542; Mature: 32411

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLGDLEVFASVAASGSMSLAAKELGYSPAVISKRIKRLEEKLGARLFQRTTRQISLTE
CCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
AGQGFYERVLAVLAGLEEAEDFVSGRANTVNGTLKVSAPTSFGRMHIAPHLKGFMERHPD
CCCHHHHHHHHHHHCHHHHHHHHCCCCEECCCEEEEECCCCCCCEEECHHHHHHHHHCCC
LSVNLVLSDEFIDIIEGGYDLAIRIADLNSSSLVARRLAPVRRVLCASADYVVAHGMPAT
CEEEEEECCHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
IEDLKKHRCLPAHNNDIWRLEGPGGALSIRPEGMLVTNSSEVIREAVISGLGIALRSTWD
HHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCEEEECHHHHHHHHHHHHCCHHHHHHHH
IGHELRSGKLVQVLPGYEGSRNVTLSAVYPSRQFLPAKVRLFIDYLAGLYGPSPYWEQG
HHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ANLGDLEVFASVAASGSMSLAAKELGYSPAVISKRIKRLEEKLGARLFQRTTRQISLTE
CCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
AGQGFYERVLAVLAGLEEAEDFVSGRANTVNGTLKVSAPTSFGRMHIAPHLKGFMERHPD
CCCHHHHHHHHHHHCHHHHHHHHCCCCEECCCEEEEECCCCCCCEEECHHHHHHHHHCCC
LSVNLVLSDEFIDIIEGGYDLAIRIADLNSSSLVARRLAPVRRVLCASADYVVAHGMPAT
CEEEEEECCHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
IEDLKKHRCLPAHNNDIWRLEGPGGALSIRPEGMLVTNSSEVIREAVISGLGIALRSTWD
HHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCEEEECHHHHHHHHHHHHCCHHHHHHHH
IGHELRSGKLVQVLPGYEGSRNVTLSAVYPSRQFLPAKVRLFIDYLAGLYGPSPYWEQG
HHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]