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The map label for this gene is aglA [H]

Identifier: 159184380

GI number: 159184380

Start: 578234

End: 579889

Strand: Direct

Name: aglA [H]

Synonym: Atu0594

Alternate gene names: 159184380

Gene position: 578234-579889 (Clockwise)

Preceding gene: 15887938

Following gene: 15887940

Centisome position: 20.35

GC content: 59.9

Gene sequence:

>1656_bases
ATGACCGCTTCGGTGACTTCCGCTTTGACGCCTAACAAGGACTGGTGGCGTGGTGCGGTGATCTATCAGATCTACCCGCG
CTCCTATCAGGACTCCAATGGCGACGGCATCGGCGATCTCAAGGGCATTACCGACCGTCTGCATCACATCGCCGGTCTCG
GTGCCGATGCGATCTGGATTTCGCCCTTTTTCACCTCGCCGATGAAGGATTTCGGCTACGACGTCTCGAACTATGTCGAT
GTCGATCCGATGTTCGGCACGCTTGCCGATTTCGACGGGCTGATTGCCGAAGCCCACCGGCTTGGCATCCGCGTGATGAT
CGACCTCGTTCTGTCGCACACGTCTGACCAGCATCCGTGGTTCGTGGAAAGCCGCGCCAGCCGCAACAATCCGAAATCGG
ACTGGTATGTCTGGTCGGAAGCGAAGCCCGATGGCACACCGCCTAACAACTGGCTGTCGATCTTCGGCGGTTCCGGCTGG
CAGTGGGATCCCACCCGCATGCAATATTACATGCACAACTTCCTGACCTCGCAACCGGACCTCAACCTGCATAACCCTGA
AGTGCAGGAGGAACTGCTTAATATCACCCGCTTCTGGCTGAAGCGCGGCGTCGATGGTTTCCGCCTCGACACTATCAACT
TCTATTTCCATGATCTGGAATTACGAGACAACCCGGCGCTGGCACCGGAGCGCCGCAATGCCTCGACCGCGCCTGCAGTC
AATCCCTACAATTTCCAGGAACATCTCTACGATAAGAACCGCCCGGAAAACATCGCCTTCCTGAAGCGCTTCCGCGCGGT
GCTGGACGAATTCCCCGATATCGCCGCCGTTGGCGAAGTGGGCGACAGCCAGCGCGGTCTCGAAATCGTCGGTGAATACA
CCTCCGGCGATGACAAGATGCAGATGTGCTATGCCTTCGAATTCCTCGCACCCGATGCGCTCACCCCCCAGCGCGTTGCC
GATGTGCAGGCGGATTTTGCGCGCGCAGCACCAGAGGGCTGGGCCTGCTGGGCCTTCTCCAACCATGATGTCGTGCGCCA
TGTCAGCCGCTGGGGCGAGCATGTCGAGGACAAGGATGCCTTCGCGAAGCTGCTGTCGGCACTGCTGATGACGCAGCGAG
GCTCCGTCTGCATCTATGAGGGCGAGGAACTGGGCCTCACTGAAGCCGATATTGCTTTCGAGGACTTACAGGACCCCTAT
GGCATCCAGTTCTGGCCGGAATTCAAGGGTCGCGATGGTTGCCGCACGCCGATGGTGTGGGATGCGGGCCATGCGCAGGC
CGGCTTTTCGACTTCGGACAAGATCTGGCTGCCCATTCCGGCCGAGCACAAGCAGCGCGCCGTCAGCGCCCAGCAGGGCA
ACGAGGCGTCGGTGCTGGAGCATTACCGCCGCTTCCTCGCCTTCCGCAAACAGCACCCGGCTTTCGCCAAGGGCGGCATC
GAATTCCAGCCGCTTGAGGGAGACGTGCTGAGCTACACCCGCAAGCTGGGCAACGAAACCATTCTGTGCCTTTTCAATCT
GTCCGCAACGCCGGCAAATGCCACGCTGCCGAAAGGGAACTGGGAGGTTCTCGAAGGCCATGGCTTTGCAAGCGGCCTTG
AAGGCACAAGCGTAGAACTTCCGGCATGGGGCGCTTTCTTCGCCCGTTACGCCTGA

Upstream 100 bases:

>100_bases
TTCTTCGCCCTTCAACGTTATCTCGTGCGTGGCCTGCTCGCGGGCTCCGTCAAGGGAGGCTGATCATTCCATGAACGCCC
ATACCAGACAGGACACTTCC

Downstream 100 bases:

>100_bases
TAGAGCAGGGAGGAACAACCCATGACAAGTCTCGTTCTCAAGGATATCCGCAAATCCTACGGGCAGGTGAAGGTCCTGCA
CGGCATCGACCTGCAGATCG

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTASVTSALTPNKDWWRGAVIYQIYPRSYQDSNGDGIGDLKGITDRLHHIAGLGADAIWISPFFTSPMKDFGYDVSNYVD
VDPMFGTLADFDGLIAEAHRLGIRVMIDLVLSHTSDQHPWFVESRASRNNPKSDWYVWSEAKPDGTPPNNWLSIFGGSGW
QWDPTRMQYYMHNFLTSQPDLNLHNPEVQEELLNITRFWLKRGVDGFRLDTINFYFHDLELRDNPALAPERRNASTAPAV
NPYNFQEHLYDKNRPENIAFLKRFRAVLDEFPDIAAVGEVGDSQRGLEIVGEYTSGDDKMQMCYAFEFLAPDALTPQRVA
DVQADFARAAPEGWACWAFSNHDVVRHVSRWGEHVEDKDAFAKLLSALLMTQRGSVCIYEGEELGLTEADIAFEDLQDPY
GIQFWPEFKGRDGCRTPMVWDAGHAQAGFSTSDKIWLPIPAEHKQRAVSAQQGNEASVLEHYRRFLAFRKQHPAFAKGGI
EFQPLEGDVLSYTRKLGNETILCLFNLSATPANATLPKGNWEVLEGHGFASGLEGTSVELPAWGAFFARYA

Sequences:

>Translated_551_residues
MTASVTSALTPNKDWWRGAVIYQIYPRSYQDSNGDGIGDLKGITDRLHHIAGLGADAIWISPFFTSPMKDFGYDVSNYVD
VDPMFGTLADFDGLIAEAHRLGIRVMIDLVLSHTSDQHPWFVESRASRNNPKSDWYVWSEAKPDGTPPNNWLSIFGGSGW
QWDPTRMQYYMHNFLTSQPDLNLHNPEVQEELLNITRFWLKRGVDGFRLDTINFYFHDLELRDNPALAPERRNASTAPAV
NPYNFQEHLYDKNRPENIAFLKRFRAVLDEFPDIAAVGEVGDSQRGLEIVGEYTSGDDKMQMCYAFEFLAPDALTPQRVA
DVQADFARAAPEGWACWAFSNHDVVRHVSRWGEHVEDKDAFAKLLSALLMTQRGSVCIYEGEELGLTEADIAFEDLQDPY
GIQFWPEFKGRDGCRTPMVWDAGHAQAGFSTSDKIWLPIPAEHKQRAVSAQQGNEASVLEHYRRFLAFRKQHPAFAKGGI
EFQPLEGDVLSYTRKLGNETILCLFNLSATPANATLPKGNWEVLEGHGFASGLEGTSVELPAWGAFFARYA
>Mature_550_residues
TASVTSALTPNKDWWRGAVIYQIYPRSYQDSNGDGIGDLKGITDRLHHIAGLGADAIWISPFFTSPMKDFGYDVSNYVDV
DPMFGTLADFDGLIAEAHRLGIRVMIDLVLSHTSDQHPWFVESRASRNNPKSDWYVWSEAKPDGTPPNNWLSIFGGSGWQ
WDPTRMQYYMHNFLTSQPDLNLHNPEVQEELLNITRFWLKRGVDGFRLDTINFYFHDLELRDNPALAPERRNASTAPAVN
PYNFQEHLYDKNRPENIAFLKRFRAVLDEFPDIAAVGEVGDSQRGLEIVGEYTSGDDKMQMCYAFEFLAPDALTPQRVAD
VQADFARAAPEGWACWAFSNHDVVRHVSRWGEHVEDKDAFAKLLSALLMTQRGSVCIYEGEELGLTEADIAFEDLQDPYG
IQFWPEFKGRDGCRTPMVWDAGHAQAGFSTSDKIWLPIPAEHKQRAVSAQQGNEASVLEHYRRFLAFRKQHPAFAKGGIE
FQPLEGDVLSYTRKLGNETILCLFNLSATPANATLPKGNWEVLEGHGFASGLEGTSVELPAWGAFFARYA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=535, Percent_Identity=32.8971962616822, Blast_Score=281, Evalue=8e-76,
Organism=Escherichia coli, GI1790687, Length=542, Percent_Identity=34.8708487084871, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1786604, Length=517, Percent_Identity=23.7911025145068, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32565753, Length=489, Percent_Identity=24.9488752556237, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25147709, Length=390, Percent_Identity=25.3846153846154, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322245, Length=587, Percent_Identity=31.0051107325383, Blast_Score=279, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6321726, Length=567, Percent_Identity=32.8042328042328, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6321731, Length=560, Percent_Identity=32.6785714285714, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6319776, Length=560, Percent_Identity=32.6785714285714, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6324416, Length=596, Percent_Identity=31.8791946308725, Blast_Score=269, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6322241, Length=596, Percent_Identity=32.3825503355705, Blast_Score=266, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6322021, Length=596, Percent_Identity=32.3825503355705, Blast_Score=266, Evalue=9e-72,
Organism=Drosophila melanogaster, GI24583745, Length=527, Percent_Identity=38.1404174573055, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24586591, Length=521, Percent_Identity=35.700575815739, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI45549022, Length=529, Percent_Identity=34.9716446124764, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24583749, Length=529, Percent_Identity=36.8620037807183, Blast_Score=318, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24583747, Length=529, Percent_Identity=36.8620037807183, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24586587, Length=507, Percent_Identity=35.5029585798817, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24586593, Length=509, Percent_Identity=36.7387033398821, Blast_Score=315, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24586597, Length=523, Percent_Identity=34.4168260038241, Blast_Score=311, Evalue=7e-85,
Organism=Drosophila melanogaster, GI24586599, Length=537, Percent_Identity=33.8919925512104, Blast_Score=311, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24586589, Length=510, Percent_Identity=35.2941176470588, Blast_Score=305, Evalue=6e-83,
Organism=Drosophila melanogaster, GI221330053, Length=568, Percent_Identity=33.4507042253521, Blast_Score=305, Evalue=7e-83,
Organism=Drosophila melanogaster, GI281360393, Length=456, Percent_Identity=33.9912280701754, Blast_Score=241, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 62147; Mature: 62016

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASVTSALTPNKDWWRGAVIYQIYPRSYQDSNGDGIGDLKGITDRLHHIAGLGADAIWI
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
SPFFTSPMKDFGYDVSNYVDVDPMFGTLADFDGLIAEAHRLGIRVMIDLVLSHTSDQHPW
CHHHCCCHHHHCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FVESRASRNNPKSDWYVWSEAKPDGTPPNNWLSIFGGSGWQWDPTRMQYYMHNFLTSQPD
EEECCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
LNLHNPEVQEELLNITRFWLKRGVDGFRLDTINFYFHDLELRDNPALAPERRNASTAPAV
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
NPYNFQEHLYDKNRPENIAFLKRFRAVLDEFPDIAAVGEVGDSQRGLEIVGEYTSGDDKM
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCCCCHH
QMCYAFEFLAPDALTPQRVADVQADFARAAPEGWACWAFSNHDVVRHVSRWGEHVEDKDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHH
FAKLLSALLMTQRGSVCIYEGEELGLTEADIAFEDLQDPYGIQFWPEFKGRDGCRTPMVW
HHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEE
DAGHAQAGFSTSDKIWLPIPAEHKQRAVSAQQGNEASVLEHYRRFLAFRKQHPAFAKGGI
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCCC
EFQPLEGDVLSYTRKLGNETILCLFNLSATPANATLPKGNWEVLEGHGFASGLEGTSVEL
EEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEC
PAWGAFFARYA
CCHHHHHHHCC
>Mature Secondary Structure 
TASVTSALTPNKDWWRGAVIYQIYPRSYQDSNGDGIGDLKGITDRLHHIAGLGADAIWI
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
SPFFTSPMKDFGYDVSNYVDVDPMFGTLADFDGLIAEAHRLGIRVMIDLVLSHTSDQHPW
CHHHCCCHHHHCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FVESRASRNNPKSDWYVWSEAKPDGTPPNNWLSIFGGSGWQWDPTRMQYYMHNFLTSQPD
EEECCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
LNLHNPEVQEELLNITRFWLKRGVDGFRLDTINFYFHDLELRDNPALAPERRNASTAPAV
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
NPYNFQEHLYDKNRPENIAFLKRFRAVLDEFPDIAAVGEVGDSQRGLEIVGEYTSGDDKM
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCCCCHH
QMCYAFEFLAPDALTPQRVADVQADFARAAPEGWACWAFSNHDVVRHVSRWGEHVEDKDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHH
FAKLLSALLMTQRGSVCIYEGEELGLTEADIAFEDLQDPYGIQFWPEFKGRDGCRTPMVW
HHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEE
DAGHAQAGFSTSDKIWLPIPAEHKQRAVSAQQGNEASVLEHYRRFLAFRKQHPAFAKGGI
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCCC
EFQPLEGDVLSYTRKLGNETILCLFNLSATPANATLPKGNWEVLEGHGFASGLEGTSVEL
EEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEC
PAWGAFFARYA
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]