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The map label for this gene is aglR [H]

Identifier: 159184378

GI number: 159184378

Start: 573201

End: 574226

Strand: Reverse

Name: aglR [H]

Synonym: Atu0590

Alternate gene names: 159184378

Gene position: 574226-573201 (Counterclockwise)

Preceding gene: 159184381

Following gene: 159184366

Centisome position: 20.21

GC content: 61.89

Gene sequence:

>1026_bases
ATGAACCTGAAACAGTTGTCGCAACTGCTGGGGATTTCGCAGACGACCATCAGCCGGGCGCTCAATGGCTATCCCGAGGT
CAGCGCGGAAACCCGCCGCCGCGTCATGGAAGCGGCCGAAAAGACCGGTTATCGCCCGAACGCAGCGGCGCAGCGGCTGG
CAACGGGCAAGGTCGGTTCCATCGGTCTTGTCATGCCCATCGGCGAGCACCACCGCTCCGACGTGCATTTCGGTGAGTTT
CTGAGCGGTCTCGGCGAGGAAGCCTCGCGCAGCGGCTTTCATCTCGTCATCATGCCGACCGAACCCGAAAATGAGCGGGA
CGCGCTCCGGGGTCTGGCGGCGAGCGGCAGCGTCGACGGCATCTATCTCGCCTACATGAAAAATAACGACCCCCGCATCG
CCATGATGCAGTCGCTCTCGCTGCCCTTCCTCGTGCATGGCCGCTCCGTCGGCGTGGAGGAGGATTATCCCTATCTCGAC
GTGGACAATGAAGGCGCCTTTCACGATGCGACCCAGCTTCTCCTGCAGCTTGGCCATACGCGCATCGGACTACTGAATGG
CCCGGAAGGTTATGATTTCACCTACCGGCGCTGTCTCGGGGTGGAAAAGGCGCTGGCGGCCAATGGGCTTTCCCTGCACC
CGGATAATAAACGGCATAGCAGCATGACGGATGAAGAAGGTTATCTCGGCATGGAGGCGCTGCTGTCACGCCCGGAAAAA
CCGACCGCCATTCTCTGCGCCAGTACGGCGCTGGCGCTCGGGGCAATCCGTTCGCTCAATCAGCGGGGGTTAAAGCCCGG
CAGGGATATTTCGCTGATCGCCCATGACGACGTGCTGCCGCTTTTGAAGCCCGATAATTTTTCGGTGCCGCTGACCACCA
CACGCTCGTCGCTGAGGGCAGCCGGGGTGCGCGTGGGTCAGCGCCTGATCAATCGCATCAAGCTCAACCAGACGGAACCG
CATCAGGAACTCTGGAAGGCGGAACTCGTGGTGCGCGCTTCGACGGGGCCGGCTCCGAAGGCGTAG

Upstream 100 bases:

>100_bases
AGAAAAGCGGATGGGACTGGTAAAAATCTAAAGCGCTTTGGGAATGTGAGGAGTGGCTTTTAGCCTTTTCCTGAGCGCGC
GCATGGAGGAAATGACAGAC

Downstream 100 bases:

>100_bases
CCGGCCGGTCAATTCAATCAGAACTTCGGCGCGGTCTTGCCGAGCGCACGATGGGCAGCGATGACGGTGTTGGCCATCAG
CATGGCGATCGTCATCGGGC

Product: transcriptional regulator repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNLKQLSQLLGISQTTISRALNGYPEVSAETRRRVMEAAEKTGYRPNAAAQRLATGKVGSIGLVMPIGEHHRSDVHFGEF
LSGLGEEASRSGFHLVIMPTEPENERDALRGLAASGSVDGIYLAYMKNNDPRIAMMQSLSLPFLVHGRSVGVEEDYPYLD
VDNEGAFHDATQLLLQLGHTRIGLLNGPEGYDFTYRRCLGVEKALAANGLSLHPDNKRHSSMTDEEGYLGMEALLSRPEK
PTAILCASTALALGAIRSLNQRGLKPGRDISLIAHDDVLPLLKPDNFSVPLTTTRSSLRAAGVRVGQRLINRIKLNQTEP
HQELWKAELVVRASTGPAPKA

Sequences:

>Translated_341_residues
MNLKQLSQLLGISQTTISRALNGYPEVSAETRRRVMEAAEKTGYRPNAAAQRLATGKVGSIGLVMPIGEHHRSDVHFGEF
LSGLGEEASRSGFHLVIMPTEPENERDALRGLAASGSVDGIYLAYMKNNDPRIAMMQSLSLPFLVHGRSVGVEEDYPYLD
VDNEGAFHDATQLLLQLGHTRIGLLNGPEGYDFTYRRCLGVEKALAANGLSLHPDNKRHSSMTDEEGYLGMEALLSRPEK
PTAILCASTALALGAIRSLNQRGLKPGRDISLIAHDDVLPLLKPDNFSVPLTTTRSSLRAAGVRVGQRLINRIKLNQTEP
HQELWKAELVVRASTGPAPKA
>Mature_341_residues
MNLKQLSQLLGISQTTISRALNGYPEVSAETRRRVMEAAEKTGYRPNAAAQRLATGKVGSIGLVMPIGEHHRSDVHFGEF
LSGLGEEASRSGFHLVIMPTEPENERDALRGLAASGSVDGIYLAYMKNNDPRIAMMQSLSLPFLVHGRSVGVEEDYPYLD
VDNEGAFHDATQLLLQLGHTRIGLLNGPEGYDFTYRRCLGVEKALAANGLSLHPDNKRHSSMTDEEGYLGMEALLSRPEK
PTAILCASTALALGAIRSLNQRGLKPGRDISLIAHDDVLPLLKPDNFSVPLTTTRSSLRAAGVRVGQRLINRIKLNQTEP
HQELWKAELVVRASTGPAPKA

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=28.3625730994152, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787948, Length=342, Percent_Identity=26.3157894736842, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789068, Length=316, Percent_Identity=27.5316455696203, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1789202, Length=279, Percent_Identity=31.1827956989247, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786540, Length=350, Percent_Identity=27.1428571428571, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790194, Length=325, Percent_Identity=26.4615384615385, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788474, Length=308, Percent_Identity=29.2207792207792, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787906, Length=331, Percent_Identity=25.3776435045317, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787580, Length=278, Percent_Identity=20.5035971223022, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=24.3161094224924, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37146; Mature: 37146

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQLSQLLGISQTTISRALNGYPEVSAETRRRVMEAAEKTGYRPNAAAQRLATGKVGS
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
IGLVMPIGEHHRSDVHFGEFLSGLGEEASRSGFHLVIMPTEPENERDALRGLAASGSVDG
EEEEECCCCCCCCCCCHHHHHHHHCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCE
IYLAYMKNNDPRIAMMQSLSLPFLVHGRSVGVEEDYPYLDVDNEGAFHDATQLLLQLGHT
EEEEEEECCCCCEEHHHHCCCCEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCC
RIGLLNGPEGYDFTYRRCLGVEKALAANGLSLHPDNKRHSSMTDEEGYLGMEALLSRPEK
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCHHHHHCCCCC
PTAILCASTALALGAIRSLNQRGLKPGRDISLIAHDDVLPLLKPDNFSVPLTTTRSSLRA
CCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEHHHHHHHH
AGVRVGQRLINRIKLNQTEPHQELWKAELVVRASTGPAPKA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCC
>Mature Secondary Structure
MNLKQLSQLLGISQTTISRALNGYPEVSAETRRRVMEAAEKTGYRPNAAAQRLATGKVGS
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
IGLVMPIGEHHRSDVHFGEFLSGLGEEASRSGFHLVIMPTEPENERDALRGLAASGSVDG
EEEEECCCCCCCCCCCHHHHHHHHCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCE
IYLAYMKNNDPRIAMMQSLSLPFLVHGRSVGVEEDYPYLDVDNEGAFHDATQLLLQLGHT
EEEEEEECCCCCEEHHHHCCCCEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCC
RIGLLNGPEGYDFTYRRCLGVEKALAANGLSLHPDNKRHSSMTDEEGYLGMEALLSRPEK
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCHHHHHCCCCC
PTAILCASTALALGAIRSLNQRGLKPGRDISLIAHDDVLPLLKPDNFSVPLTTTRSSLRA
CCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEHHHHHHHH
AGVRVGQRLINRIKLNQTEPHQELWKAELVVRASTGPAPKA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]