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The map label for this gene is yehW [H]

Identifier: 159184204

GI number: 159184204

Start: 200281

End: 201021

Strand: Reverse

Name: yehW [H]

Synonym: Atu0196

Alternate gene names: 159184204

Gene position: 201021-200281 (Counterclockwise)

Preceding gene: 15887550

Following gene: 15887548

Centisome position: 7.07

GC content: 62.08

Gene sequence:

>741_bases
ATGAAAAACGCCTTCTCTTTTCTCTCTCTCGGGCTTCTGGTGCTGGCGCTGATCATTTTTCTTGCCGCGCCGCAAATCTT
CGCACCGATCTTCCGCCCTCTCGTGCAGGCCAATGCGCCGGCCATCTACACGCAGGCCAATCTCTTTTCCCTGACGCTGT
CGCATCTGACCATCGTTGCGATCGCGACCGGCCTCGCCACGCTCACGGCAGGGGCGCTTGCGGTTCTCGTCACCCGGCCT
TTCGGGGCGGATTTCCTGCCGCTGTCGCGCAGCATCGTCAATATCGGCCAGACCTTTCCGCCGGTGGCGGTGTTGGCGCT
GGCCGTGCCGATGATCGGCTTTGGCGAGAAACCCACGCTCATCGCCCTGTTTCTCTATGCACTTCTGCCGGTGTTCGAAA
ATACGCTGACCGGGCTGACAACCCTGCCCGCCACGGTGATGGATGCCGCCAGAGGCAGCGGTATGACCGGCTGGCAACGG
CTCACCAAAGTGGAGCTGCCGCTTGCCCTTCCGGCCATTCTCGCCGGCGTCAGGCTGTCGGCGGTCATCAGCCTTTCCAC
CGCGACCATTGGGTCCACGGTTGCCGCCCGCACGCTCGGCGAAGTGATCATCGCCGGCCTGCAATCCAACAATCTCGCCT
TCATTCTCCAGGGCGGTTTGATCGTTGCTGCACTGGCGATCCTGATCCACGCTGGCTTTTCCGCACTGGAAAGATCCGCA
GCCCGCAAAACCGGACACTGA

Upstream 100 bases:

>100_bases
TATGGGCGGGTCGCGATGTCTTGCCTGTCATAAAGGACGATGGGCAACCCATTGGCCGGGTGCGGCGTGATGTTCTCCTT
CAGCGTGCCACTGGCGCCCC

Downstream 100 bases:

>100_bases
CATGCGGAGCCGTCCAAATTTAAGGTTCCCGGCACCCGCCGCACATGGTAGGGGCTGACCGTCGAAACAGAAACATCAGA
GGTTCGGGTGACACAGGCAA

Product: ABC transporter, membrane spanning protein (proline/glycine/betaine)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKNAFSFLSLGLLVLALIIFLAAPQIFAPIFRPLVQANAPAIYTQANLFSLTLSHLTIVAIATGLATLTAGALAVLVTRP
FGADFLPLSRSIVNIGQTFPPVAVLALAVPMIGFGEKPTLIALFLYALLPVFENTLTGLTTLPATVMDAARGSGMTGWQR
LTKVELPLALPAILAGVRLSAVISLSTATIGSTVAARTLGEVIIAGLQSNNLAFILQGGLIVAALAILIHAGFSALERSA
ARKTGH

Sequences:

>Translated_246_residues
MKNAFSFLSLGLLVLALIIFLAAPQIFAPIFRPLVQANAPAIYTQANLFSLTLSHLTIVAIATGLATLTAGALAVLVTRP
FGADFLPLSRSIVNIGQTFPPVAVLALAVPMIGFGEKPTLIALFLYALLPVFENTLTGLTTLPATVMDAARGSGMTGWQR
LTKVELPLALPAILAGVRLSAVISLSTATIGSTVAARTLGEVIIAGLQSNNLAFILQGGLIVAALAILIHAGFSALERSA
ARKTGH
>Mature_246_residues
MKNAFSFLSLGLLVLALIIFLAAPQIFAPIFRPLVQANAPAIYTQANLFSLTLSHLTIVAIATGLATLTAGALAVLVTRP
FGADFLPLSRSIVNIGQTFPPVAVLALAVPMIGFGEKPTLIALFLYALLPVFENTLTGLTTLPATVMDAARGSGMTGWQR
LTKVELPLALPAILAGVRLSAVISLSTATIGSTVAARTLGEVIIAGLQSNNLAFILQGGLIVAALAILIHAGFSALERSA
ARKTGH

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=231, Percent_Identity=46.7532467532467, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI1788451, Length=162, Percent_Identity=37.037037037037, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789033, Length=157, Percent_Identity=31.2101910828025, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25461; Mature: 25461

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAFSFLSLGLLVLALIIFLAAPQIFAPIFRPLVQANAPAIYTQANLFSLTLSHLTIVA
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
IATGLATLTAGALAVLVTRPFGADFLPLSRSIVNIGQTFPPVAVLALAVPMIGFGEKPTL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHH
IALFLYALLPVFENTLTGLTTLPATVMDAARGSGMTGWQRLTKVELPLALPAILAGVRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
AVISLSTATIGSTVAARTLGEVIIAGLQSNNLAFILQGGLIVAALAILIHAGFSALERSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ARKTGH
HHCCCC
>Mature Secondary Structure
MKNAFSFLSLGLLVLALIIFLAAPQIFAPIFRPLVQANAPAIYTQANLFSLTLSHLTIVA
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
IATGLATLTAGALAVLVTRPFGADFLPLSRSIVNIGQTFPPVAVLALAVPMIGFGEKPTL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHH
IALFLYALLPVFENTLTGLTTLPATVMDAARGSGMTGWQRLTKVELPLALPAILAGVRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
AVISLSTATIGSTVAARTLGEVIIAGLQSNNLAFILQGGLIVAALAILIHAGFSALERSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ARKTGH
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]