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The map label for this gene is allD [C]

Identifier: 159184191

GI number: 159184191

Start: 169337

End: 170326

Strand: Direct

Name: allD [C]

Synonym: Atu0164

Alternate gene names: 159184191

Gene position: 169337-170326 (Clockwise)

Preceding gene: 15887518

Following gene: 15887536

Centisome position: 5.96

GC content: 62.22

Gene sequence:

>990_bases
ATGAAATTCTCAATCGCAGAGGCGGAGGATCTCGTATCCTCTATCTTTGAGCGCAATGGCGTTCTGCCGCAAAATGCCCG
TTCTGTGGCAAAGGCGCTGGTCGCCTCCGAGGCGGCTGGCCAGGGCGGCCATGGTTTTCGCCGTATTCCCGTTTATGTCC
GTCAGGCGCGGGTTGGAAAGGTGGACGGTCAGGCGCGTCCCGTGGTGAGGCGCGTGAAGCCGGGCGTGCTCTCGATCGAC
GCCAATCATGGTTATGCCTATCCGGCGATCGACTGCGCTCTTGAAGAATTGCCTGAAATGGCCCGACAGCAGGGCATTGC
GCTGGCAGCGATCCATCGCTCCCACCATGCAGGCGTCATGGCTCTGACGGTCGAGCGTTTTGCGGAAATGGGCCTTGTCG
CGCTCATGTTCGCCAATGCACCAGCCTCCATGGCTCCCTGGGGCGGCCACACGCCGCTTTATGGCACCAACCCCATCGCC
TTTGCGGCCCCCATTGGCGGCGCCGATCCGCTCGTCATCGATCTGGCCCTGTCAAAGGTCGCGCGCGGCAAGATCATGGC
GGCACGACAGAAGGGTGAAACCATTCCCGGCGACTGGGCGCTCGATAGAAACGGCCGGCCGACGACCGATCCAGAGGAGG
CCATTGCCGGAACCATGGTCCCCGCGGGTGAAGCCAAGGGCGCTGCTCTGGCGCTGATGGTGGAGATCATGGCAGCTGCG
GTGACTGGTGGAAATTTCGCATTCCAGGCATCGTCCCTTCTGGATGATAAGGGTGCGCCGCCCTCCCTCGGCCATACGAT
CATCGCCATCGACCCGGTATCCTCTGGCGGCGCAGCCTTTACCGAGCGGCTGGCCCTCATCGCGGGTGAGATCGAAAAGC
AGGAAAATGTGCGGTTGCCCGGTCGCCGCAGCCAGGGCATCCGCAAGCAGGCGCTCGAAAGCGGCATTGCGATCGAAAGC
GACATTCTGGCCGAAATCCAATCGCTTTGA

Upstream 100 bases:

>100_bases
GTGGCCGGTTCATTTTCCATGTTGATTTGCAGCGACCCTATGCCGCAAAGTGGGGCTCATACATCCCATCGCATGCGAGC
CAACAGGAATCACGAAAATC

Downstream 100 bases:

>100_bases
ACCGACAAGAAAAACCCGGCGGATCGAATATGATCCGCCGGGCAAACCGGATATGGCTGCTTCGCATTTGCGTCGATTGG
GCCGGACATCATGTCCAGCC

Product: putative malate dehydrogenase

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKFSIAEAEDLVSSIFERNGVLPQNARSVAKALVASEAAGQGGHGFRRIPVYVRQARVGKVDGQARPVVRRVKPGVLSID
ANHGYAYPAIDCALEELPEMARQQGIALAAIHRSHHAGVMALTVERFAEMGLVALMFANAPASMAPWGGHTPLYGTNPIA
FAAPIGGADPLVIDLALSKVARGKIMAARQKGETIPGDWALDRNGRPTTDPEEAIAGTMVPAGEAKGAALALMVEIMAAA
VTGGNFAFQASSLLDDKGAPPSLGHTIIAIDPVSSGGAAFTERLALIAGEIEKQENVRLPGRRSQGIRKQALESGIAIES
DILAEIQSL

Sequences:

>Translated_329_residues
MKFSIAEAEDLVSSIFERNGVLPQNARSVAKALVASEAAGQGGHGFRRIPVYVRQARVGKVDGQARPVVRRVKPGVLSID
ANHGYAYPAIDCALEELPEMARQQGIALAAIHRSHHAGVMALTVERFAEMGLVALMFANAPASMAPWGGHTPLYGTNPIA
FAAPIGGADPLVIDLALSKVARGKIMAARQKGETIPGDWALDRNGRPTTDPEEAIAGTMVPAGEAKGAALALMVEIMAAA
VTGGNFAFQASSLLDDKGAPPSLGHTIIAIDPVSSGGAAFTERLALIAGEIEKQENVRLPGRRSQGIRKQALESGIAIES
DILAEIQSL
>Mature_329_residues
MKFSIAEAEDLVSSIFERNGVLPQNARSVAKALVASEAAGQGGHGFRRIPVYVRQARVGKVDGQARPVVRRVKPGVLSID
ANHGYAYPAIDCALEELPEMARQQGIALAAIHRSHHAGVMALTVERFAEMGLVALMFANAPASMAPWGGHTPLYGTNPIA
FAAPIGGADPLVIDLALSKVARGKIMAARQKGETIPGDWALDRNGRPTTDPEEAIAGTMVPAGEAKGAALALMVEIMAAA
VTGGNFAFQASSLLDDKGAPPSLGHTIIAIDPVSSGGAAFTERLALIAGEIEKQENVRLPGRRSQGIRKQALESGIAIES
DILAEIQSL

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=335, Percent_Identity=29.8507462686567, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787020, Length=329, Percent_Identity=30.3951367781155, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790000, Length=340, Percent_Identity=22.6470588235294, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17507179, Length=302, Percent_Identity=28.8079470198675, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17536633, Length=285, Percent_Identity=26.3157894736842, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24667908, Length=292, Percent_Identity=28.0821917808219, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45553211, Length=292, Percent_Identity=28.0821917808219, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24667912, Length=292, Percent_Identity=28.0821917808219, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24667904, Length=292, Percent_Identity=28.0821917808219, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24648360, Length=291, Percent_Identity=30.2405498281787, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24658010, Length=305, Percent_Identity=26.2295081967213, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 34371; Mature: 34371

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSIAEAEDLVSSIFERNGVLPQNARSVAKALVASEAAGQGGHGFRRIPVYVRQARVGK
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHCCC
VDGQARPVVRRVKPGVLSIDANHGYAYPAIDCALEELPEMARQQGIALAAIHRSHHAGVM
CCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCE
ALTVERFAEMGLVALMFANAPASMAPWGGHTPLYGTNPIAFAAPIGGADPLVIDLALSKV
EHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHHHHH
ARGKIMAARQKGETIPGDWALDRNGRPTTDPEEAIAGTMVPAGEAKGAALALMVEIMAAA
HHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VTGGNFAFQASSLLDDKGAPPSLGHTIIAIDPVSSGGAAFTERLALIAGEIEKQENVRLP
HCCCCEEEEHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
GRRSQGIRKQALESGIAIESDILAEIQSL
CCCCCHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKFSIAEAEDLVSSIFERNGVLPQNARSVAKALVASEAAGQGGHGFRRIPVYVRQARVGK
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHCCC
VDGQARPVVRRVKPGVLSIDANHGYAYPAIDCALEELPEMARQQGIALAAIHRSHHAGVM
CCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCE
ALTVERFAEMGLVALMFANAPASMAPWGGHTPLYGTNPIAFAAPIGGADPLVIDLALSKV
EHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHHHHH
ARGKIMAARQKGETIPGDWALDRNGRPTTDPEEAIAGTMVPAGEAKGAALALMVEIMAAA
HHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VTGGNFAFQASSLLDDKGAPPSLGHTIIAIDPVSSGGAAFTERLALIAGEIEKQENVRLP
HCCCCEEEEHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
GRRSQGIRKQALESGIAIESDILAEIQSL
CCCCCHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]