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The map label for this gene is yjjN [H]

Identifier: 15890061

GI number: 15890061

Start: 2817161

End: 2818171

Strand: Reverse

Name: yjjN [H]

Synonym: Atu2814

Alternate gene names: 15890061

Gene position: 2818171-2817161 (Counterclockwise)

Preceding gene: 159185394

Following gene: 15890060

Centisome position: 99.18

GC content: 59.25

Gene sequence:

>1011_bases
ATGCTGGCGATTTTCTGTGACACTCCCGGTCAATTAACCGCCAAGGATCTGCCGAACCCCGTGCGCGGCGAAGGTGAAGT
CCTGGTACGTATTCGCCGGATTGGCGTTTGCGGCACGGATCTGCACATCTTTACCGGCAACCAGCCCTATCTTTCCTATC
CGCGGATCATGGGTCACGAACTTTCCGGCACGGTTGAGGAGGCACCCGCTGGCAGCCACCTTTCCGCTGGCGATGTGGTG
ACCATAATTCCCTATATGTCCTGCGGGAAATGCAATGCCTGCCTGAAGGGTAAGAGCAATTGCTGCCGCAATATCGGTGT
GCTTGGCGTTCATCGCGATGGCGGCATGGTGGAATATCTGAGCGTGCCGCAGCAATTCGTGCTGAAGGCGGAGGGGCTGA
GCCTCGACCAGGCAGCCATGACGGAATTTCTGGCGATCGGTGCCCATGCGGTGCGTCGCGGTGCCGTCGAAAAAGGGCAA
AAGGTCCTGATCGTCGGTGCCGGCCCGATCGGCATGGCGGTTGCTGTCTTTGCGGTTCTCGATGGCACGGAAGTGACGAT
GATCGACGGTCGCACCGACCGGCTGGATTTCTGCAAGGACCACCTCGGTGTCGCTCATACAGTCGCCCTCGGCGACGGTG
ACAAAGATCGTCTGTCCGACATTACCGGTGGCAATTTCTTCGATGCGGTGTTTGATGCGACCGGCAATCCGAAAGCCATG
GAGCGCGGTTTCTCCTTCGTCGGTCACGGCGGCTCCTATGTTCTGGTGTCCATCGTCGCCAGCGATATCAGCTTCAACGA
CCCGGAATTTCACAAGCGTGAGACGACGCTGCTCGGCAGCCGCAACGCGACGGCTGATGATTTCGAGCGGGTGCTTCGCG
CCTTGCGCGAAGGGAAAGTGCCGGAGGCACTAATCACCCATCGCATGACACTTGCCGATGTTCCCTCGAAGTTCGCCGGC
CTGACCGATCCGAAAGCCGGAGTCATCAAGGGCATGGTGGAGGTCGCATGA

Upstream 100 bases:

>100_bases
CTGGCTGGATTTCTGCCGCGATATCGTGCCGGCGAAGGACCATGCGGCAGTTTTCGGCGGCAACGCCATTCGTTTTTACT
CCCTTACTGACAGGTGATGC

Downstream 100 bases:

>100_bases
CACCCGATACGCCCATCCTGCAATTCGGCACCAGCCGTTTTCTTCTCGCCCATGCGGATCTGTTCGTTTCGCAGGCGCTC
GATAGTGGCGAGGCGCTGGG

Product: zinc-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MLAIFCDTPGQLTAKDLPNPVRGEGEVLVRIRRIGVCGTDLHIFTGNQPYLSYPRIMGHELSGTVEEAPAGSHLSAGDVV
TIIPYMSCGKCNACLKGKSNCCRNIGVLGVHRDGGMVEYLSVPQQFVLKAEGLSLDQAAMTEFLAIGAHAVRRGAVEKGQ
KVLIVGAGPIGMAVAVFAVLDGTEVTMIDGRTDRLDFCKDHLGVAHTVALGDGDKDRLSDITGGNFFDAVFDATGNPKAM
ERGFSFVGHGGSYVLVSIVASDISFNDPEFHKRETTLLGSRNATADDFERVLRALREGKVPEALITHRMTLADVPSKFAG
LTDPKAGVIKGMVEVA

Sequences:

>Translated_336_residues
MLAIFCDTPGQLTAKDLPNPVRGEGEVLVRIRRIGVCGTDLHIFTGNQPYLSYPRIMGHELSGTVEEAPAGSHLSAGDVV
TIIPYMSCGKCNACLKGKSNCCRNIGVLGVHRDGGMVEYLSVPQQFVLKAEGLSLDQAAMTEFLAIGAHAVRRGAVEKGQ
KVLIVGAGPIGMAVAVFAVLDGTEVTMIDGRTDRLDFCKDHLGVAHTVALGDGDKDRLSDITGGNFFDAVFDATGNPKAM
ERGFSFVGHGGSYVLVSIVASDISFNDPEFHKRETTLLGSRNATADDFERVLRALREGKVPEALITHRMTLADVPSKFAG
LTDPKAGVIKGMVEVA
>Mature_336_residues
MLAIFCDTPGQLTAKDLPNPVRGEGEVLVRIRRIGVCGTDLHIFTGNQPYLSYPRIMGHELSGTVEEAPAGSHLSAGDVV
TIIPYMSCGKCNACLKGKSNCCRNIGVLGVHRDGGMVEYLSVPQQFVLKAEGLSLDQAAMTEFLAIGAHAVRRGAVEKGQ
KVLIVGAGPIGMAVAVFAVLDGTEVTMIDGRTDRLDFCKDHLGVAHTVALGDGDKDRLSDITGGNFFDAVFDATGNPKAM
ERGFSFVGHGGSYVLVSIVASDISFNDPEFHKRETTLLGSRNATADDFERVLRALREGKVPEALITHRMTLADVPSKFAG
LTDPKAGVIKGMVEVA

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=268, Percent_Identity=29.4776119402985, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI71565154, Length=247, Percent_Identity=28.7449392712551, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI226510992, Length=339, Percent_Identity=40.4129793510324, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1787863, Length=321, Percent_Identity=30.2180685358255, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788073, Length=345, Percent_Identity=28.4057971014493, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788407, Length=324, Percent_Identity=29.0123456790123, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790045, Length=329, Percent_Identity=26.4437689969605, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790718, Length=307, Percent_Identity=28.3387622149837, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082125, Length=352, Percent_Identity=26.4204545454545, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786825, Length=266, Percent_Identity=26.6917293233083, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788075, Length=348, Percent_Identity=22.7011494252874, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081918, Length=315, Percent_Identity=27.6190476190476, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=281, Percent_Identity=30.9608540925267, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17562878, Length=186, Percent_Identity=31.1827956989247, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=171, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562582, Length=339, Percent_Identity=27.4336283185841, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=337, Percent_Identity=27.299703264095, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=332, Percent_Identity=27.1084337349398, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319955, Length=332, Percent_Identity=27.1084337349398, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319258, Length=355, Percent_Identity=25.9154929577465, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319257, Length=346, Percent_Identity=28.6127167630058, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323099, Length=348, Percent_Identity=25.2873563218391, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=27.2189349112426, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=196, Percent_Identity=30.6122448979592, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17137530, Length=333, Percent_Identity=29.1291291291291, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI17737897, Length=336, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45550770, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221457811, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45551930, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35714; Mature: 35714

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAIFCDTPGQLTAKDLPNPVRGEGEVLVRIRRIGVCGTDLHIFTGNQPYLSYPRIMGHE
CEEEEECCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCHHHCCC
LSGTVEEAPAGSHLSAGDVVTIIPYMSCGKCNACLKGKSNCCRNIGVLGVHRDGGMVEYL
CCCCHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCHHHHHCCCEEEEECCCCEEHHH
SVPQQFVLKAEGLSLDQAAMTEFLAIGAHAVRRGAVEKGQKVLIVGAGPIGMAVAVFAVL
HCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHC
DGTEVTMIDGRTDRLDFCKDHLGVAHTVALGDGDKDRLSDITGGNFFDAVFDATGNPKAM
CCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCHHHHHHCCCCCHHHH
ERGFSFVGHGGSYVLVSIVASDISFNDPEFHKRETTLLGSRNATADDFERVLRALREGKV
HHCCCEECCCCCEEEEEEEHHCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHCCCC
PEALITHRMTLADVPSKFAGLTDPKAGVIKGMVEVA
CHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLAIFCDTPGQLTAKDLPNPVRGEGEVLVRIRRIGVCGTDLHIFTGNQPYLSYPRIMGHE
CEEEEECCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCHHHCCC
LSGTVEEAPAGSHLSAGDVVTIIPYMSCGKCNACLKGKSNCCRNIGVLGVHRDGGMVEYL
CCCCHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCHHHHHCCCEEEEECCCCEEHHH
SVPQQFVLKAEGLSLDQAAMTEFLAIGAHAVRRGAVEKGQKVLIVGAGPIGMAVAVFAVL
HCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHC
DGTEVTMIDGRTDRLDFCKDHLGVAHTVALGDGDKDRLSDITGGNFFDAVFDATGNPKAM
CCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCHHHHHHCCCCCHHHH
ERGFSFVGHGGSYVLVSIVASDISFNDPEFHKRETTLLGSRNATADDFERVLRALREGKV
HHCCCEECCCCCEEEEEEEHHCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHCCCC
PEALITHRMTLADVPSKFAGLTDPKAGVIKGMVEVA
CHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]