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The map label for this gene is uxaB [H]

Identifier: 15890060

GI number: 15890060

Start: 2816031

End: 2817164

Strand: Reverse

Name: uxaB [H]

Synonym: Atu2813

Alternate gene names: 15890060

Gene position: 2817164-2816031 (Counterclockwise)

Preceding gene: 15890061

Following gene: 159185393

Centisome position: 99.14

GC content: 60.76

Gene sequence:

>1134_bases
ATGACACCCGATACGCCCATCCTGCAATTCGGCACCAGCCGTTTTCTTCTCGCCCATGCGGATCTGTTCGTTTCGCAGGC
GCTCGATAGTGGCGAGGCGCTGGGCCGCATTGCAATCGTCCAGACGACCGGCAATGCCGAGAGCCTGAAGCGCGTTGCGG
CGCTGAACAGCGGCGCACCCTACCCCGTGCGTATTCGCGGTATCAGCGATGGGCAGGAAGTTGACGAGGAAATTCAGGGC
AAGGCAGTCGCGCGGGCTTTGACCGCCGCGACCGATTGGGCCGAGGTGCGCCGTCTCGCCTGTGTGGTCGAGGTCATTCT
GTCCAACACGGGCGATCGCGGTTATGAGCTGGATTCGGGCGACGGACCCGAGCTTGCCGCCGATTTCACCATCGTGCCGA
AAAGCTTTCCGGCGAAGCTTTGCATGCTGCTGCTGGAGCGTTTTGAGCTTAATCCCGAAGCGCCCGTCTCGATTTTCCCC
TGCGAGCTCGTGCCGCGCAACGGCGAAAAGCTGAGCCAAGTCATTCGCCGGCTTGCAGACGAATGGCAATTGCCGGCGGG
TTTTGCCTTCTATCTGAATGAGAAGTGCCGTTTCGCCAATAGTCTGGTGGACCGCATCGTCTCCGAGCCGATCGATCCTG
TCGGCGCCGTGGCGGAACCCTATGCACTCTGGGCGATCGAGAAACAGGAAGGTCTCGTCCTTCCCTGTACCCACCCCGCG
GTGGTGCTGACAGATGATCTCGACCACTATGAAAAACTGAAGTTGTTCCTGCTCAATCTCGGTCACTCCTATCTGGCGGA
GCGCTGGGTGCAGGATGCACGCTCGAAGGGAGAGACGGTGCGGCAGGCCATGGCCGACGACGCTCTGGTGGCGGATATGG
AAGCGCTCTGGCACGACGAGGTTCTGCCGGTCTTTGCAGCTGAAGGCATGGGAGACGAGGCGAAAGCCTATATCGGCCTG
TTGCGGGAGCGTTTGCGCAATCCCTTTCTCGCGCATCGCCTTGCCGATATCGCCGGCAACCATGACGAAAAGAAGCGCCG
CCGTTTTGCCCCGGTCATTGCCGCCGCCGAAAGGCTGGAATTGAAGTTGCCGCAGTCGAAGCTGCGTGCGGCGCTTGCCG
CCATCAAGCAATAA

Upstream 100 bases:

>100_bases
CACTAATCACCCATCGCATGACACTTGCCGATGTTCCCTCGAAGTTCGCCGGCCTGACCGATCCGAAAGCCGGAGTCATC
AAGGGCATGGTGGAGGTCGC

Downstream 100 bases:

>100_bases
TGGAGTTTTTCATGCAGCGCATGGGCATGGTCATCGGCGTCAAGCCTGAGATGATCGCGGAATATAAAAGGCTGCACGCC
GCGGTCTGGCCGGAGGTTCT

Product: altronate oxidoreductase

Products: NA

Alternate protein names: Tagaturonate dehydrogenase; Tagaturonate reductase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTPDTPILQFGTSRFLLAHADLFVSQALDSGEALGRIAIVQTTGNAESLKRVAALNSGAPYPVRIRGISDGQEVDEEIQG
KAVARALTAATDWAEVRRLACVVEVILSNTGDRGYELDSGDGPELAADFTIVPKSFPAKLCMLLLERFELNPEAPVSIFP
CELVPRNGEKLSQVIRRLADEWQLPAGFAFYLNEKCRFANSLVDRIVSEPIDPVGAVAEPYALWAIEKQEGLVLPCTHPA
VVLTDDLDHYEKLKLFLLNLGHSYLAERWVQDARSKGETVRQAMADDALVADMEALWHDEVLPVFAAEGMGDEAKAYIGL
LRERLRNPFLAHRLADIAGNHDEKKRRRFAPVIAAAERLELKLPQSKLRAALAAIKQ

Sequences:

>Translated_377_residues
MTPDTPILQFGTSRFLLAHADLFVSQALDSGEALGRIAIVQTTGNAESLKRVAALNSGAPYPVRIRGISDGQEVDEEIQG
KAVARALTAATDWAEVRRLACVVEVILSNTGDRGYELDSGDGPELAADFTIVPKSFPAKLCMLLLERFELNPEAPVSIFP
CELVPRNGEKLSQVIRRLADEWQLPAGFAFYLNEKCRFANSLVDRIVSEPIDPVGAVAEPYALWAIEKQEGLVLPCTHPA
VVLTDDLDHYEKLKLFLLNLGHSYLAERWVQDARSKGETVRQAMADDALVADMEALWHDEVLPVFAAEGMGDEAKAYIGL
LRERLRNPFLAHRLADIAGNHDEKKRRRFAPVIAAAERLELKLPQSKLRAALAAIKQ
>Mature_376_residues
TPDTPILQFGTSRFLLAHADLFVSQALDSGEALGRIAIVQTTGNAESLKRVAALNSGAPYPVRIRGISDGQEVDEEIQGK
AVARALTAATDWAEVRRLACVVEVILSNTGDRGYELDSGDGPELAADFTIVPKSFPAKLCMLLLERFELNPEAPVSIFPC
ELVPRNGEKLSQVIRRLADEWQLPAGFAFYLNEKCRFANSLVDRIVSEPIDPVGAVAEPYALWAIEKQEGLVLPCTHPAV
VLTDDLDHYEKLKLFLLNLGHSYLAERWVQDARSKGETVRQAMADDALVADMEALWHDEVLPVFAAEGMGDEAKAYIGLL
RERLRNPFLAHRLADIAGNHDEKKRRRFAPVIAAAERLELKLPQSKLRAALAAIKQ

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxaB subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994885, Length=396, Percent_Identity=30.050505050505, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788497, Length=374, Percent_Identity=24.5989304812834, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790028, Length=243, Percent_Identity=27.5720164609054, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.58 [H]

Molecular weight: Translated: 41553; Mature: 41422

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDTPILQFGTSRFLLAHADLFVSQALDSGEALGRIAIVQTTGNAESLKRVAALNSGAP
CCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCC
YPVRIRGISDGQEVDEEIQGKAVARALTAATDWAEVRRLACVVEVILSNTGDRGYELDSG
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DGPELAADFTIVPKSFPAKLCMLLLERFELNPEAPVSIFPCELVPRNGEKLSQVIRRLAD
CCCCCEECEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
EWQLPAGFAFYLNEKCRFANSLVDRIVSEPIDPVGAVAEPYALWAIEKQEGLVLPCTHPA
HCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEECCCCEEEECCCCC
VVLTDDLDHYEKLKLFLLNLGHSYLAERWVQDARSKGETVRQAMADDALVADMEALWHDE
EEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VLPVFAAEGMGDEAKAYIGLLRERLRNPFLAHRLADIAGNHDEKKRRRFAPVIAAAERLE
CHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LKLPQSKLRAALAAIKQ
HCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TPDTPILQFGTSRFLLAHADLFVSQALDSGEALGRIAIVQTTGNAESLKRVAALNSGAP
CCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCC
YPVRIRGISDGQEVDEEIQGKAVARALTAATDWAEVRRLACVVEVILSNTGDRGYELDSG
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DGPELAADFTIVPKSFPAKLCMLLLERFELNPEAPVSIFPCELVPRNGEKLSQVIRRLAD
CCCCCEECEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
EWQLPAGFAFYLNEKCRFANSLVDRIVSEPIDPVGAVAEPYALWAIEKQEGLVLPCTHPA
HCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEECCCCEEEECCCCC
VVLTDDLDHYEKLKLFLLNLGHSYLAERWVQDARSKGETVRQAMADDALVADMEALWHDE
EEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VLPVFAAEGMGDEAKAYIGLLRERLRNPFLAHRLADIAGNHDEKKRRRFAPVIAAAERLE
CHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LKLPQSKLRAALAAIKQ
HCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]