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The map label for this gene is cobI [H]

Identifier: 15890048

GI number: 15890048

Start: 2802228

End: 2802995

Strand: Reverse

Name: cobI [H]

Synonym: Atu2801

Alternate gene names: 15890048

Gene position: 2802995-2802228 (Counterclockwise)

Preceding gene: 15890049

Following gene: 15890047

Centisome position: 98.64

GC content: 61.33

Gene sequence:

>768_bases
GTGAGTGCTGCGCTTTTTGAACATGCCAAGGGTAAGCTTGTCGGCGTCGGCACTGGTCCGGGTGATCCTGAGCTGCTGAC
GCTGAAAGCCGTGCGCGCCATCGAAAATGCCGATGTTCTCGCCTTTTTCTGCAAGAAGGGCAGCGCCGGCAATGGCCGTG
GCATTGTCGAAGCCTTTATTCGACCCGGCACGCTTGAAATGCCGCTGGTCTATCCCGTCACTGTCGAAAGCGACAAGAAC
GGCGAAGATTATCGCGGCGCGATTGCCGCGTTCTTTGATCAGTCCGCGAAGGATATTGCCGTGCATCTCGATGCCGGGCG
CAATGTGGCCGTGCTCTCTGAAGGCGATCCGCTGTTTTACGGCTCCTATATGCATCTCCATCTGCGGCTTGCGCCGTCCT
ATGAGGCGGAAGTCGTTGCCGGCATCACCGCCATGTCCGGTTGCTGGTCCATGGCCGGCCTGCCGCTCGTGCAGGGCGAC
GATATTCTGAGCGTGCTTCCCGGCACGCTGGCAGAAGAGGTGCTCGCGGAGCGACTTTCCGGCACGGATGGCGCCGTGAT
CATGAAGGTCGGCCGCAATCTGCCGAAAATCCGCCGCGCGCTGGAAGTGGCCGGCAAGCTCGAAGAGGCGCTGTATGTCG
AGCGCGGCACCATGGCGAACAGCCACGCGGTGCGGCTCATCGAGCGTGATGCCTCGCCCGCGCCCTATTTTTCGCTGGTT
CTGGTACCAGGCTGGAAAACCAGGCCAGCAGGGAGCGAAGGGTCATGA

Upstream 100 bases:

>100_bases
AGGCAAGTGCGCTTGGCATTCCCTATGCTATCGTCAAGGGACGTTTGGGCGGCTCGGCCATGACGGCCGCCGCCATCAAC
GCGGTTGCGAGGGCGGGCCT

Downstream 100 bases:

>100_bases
CCGGCAAACTCGTTGTTATCGGCCTTGGTCCCGGCAACGGAAATCAGGTGACGCCTGAGGCGCTGGCCGCTGTCGAGTCA
TCGGAAGATTTTTTCGGTTA

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSAALFEHAKGKLVGVGTGPGDPELLTLKAVRAIENADVLAFFCKKGSAGNGRGIVEAFIRPGTLEMPLVYPVTVESDKN
GEDYRGAIAAFFDQSAKDIAVHLDAGRNVAVLSEGDPLFYGSYMHLHLRLAPSYEAEVVAGITAMSGCWSMAGLPLVQGD
DILSVLPGTLAEEVLAERLSGTDGAVIMKVGRNLPKIRRALEVAGKLEEALYVERGTMANSHAVRLIERDASPAPYFSLV
LVPGWKTRPAGSEGS

Sequences:

>Translated_255_residues
MSAALFEHAKGKLVGVGTGPGDPELLTLKAVRAIENADVLAFFCKKGSAGNGRGIVEAFIRPGTLEMPLVYPVTVESDKN
GEDYRGAIAAFFDQSAKDIAVHLDAGRNVAVLSEGDPLFYGSYMHLHLRLAPSYEAEVVAGITAMSGCWSMAGLPLVQGD
DILSVLPGTLAEEVLAERLSGTDGAVIMKVGRNLPKIRRALEVAGKLEEALYVERGTMANSHAVRLIERDASPAPYFSLV
LVPGWKTRPAGSEGS
>Mature_254_residues
SAALFEHAKGKLVGVGTGPGDPELLTLKAVRAIENADVLAFFCKKGSAGNGRGIVEAFIRPGTLEMPLVYPVTVESDKNG
EDYRGAIAAFFDQSAKDIAVHLDAGRNVAVLSEGDPLFYGSYMHLHLRLAPSYEAEVVAGITAMSGCWSMAGLPLVQGDD
ILSVLPGTLAEEVLAERLSGTDGAVIMKVGRNLPKIRRALEVAGKLEEALYVERGTMANSHAVRLIERDASPAPYFSLVL
VPGWKTRPAGSEGS

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27007; Mature: 26876

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAALFEHAKGKLVGVGTGPGDPELLTLKAVRAIENADVLAFFCKKGSAGNGRGIVEAFI
CCCCHHHCCCCCEEEEECCCCCCCEEEHHHHHHHCCCCEEEEEECCCCCCCCCCHHEEEE
RPGTLEMPLVYPVTVESDKNGEDYRGAIAAFFDQSAKDIAVHLDAGRNVAVLSEGDPLFY
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCEEE
GSYMHLHLRLAPSYEAEVVAGITAMSGCWSMAGLPLVQGDDILSVLPGTLAEEVLAERLS
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHCCHHHHHHHHHHHHC
GTDGAVIMKVGRNLPKIRRALEVAGKLEEALYVERGTMANSHAVRLIERDASPAPYFSLV
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCCEEEEE
LVPGWKTRPAGSEGS
EECCCCCCCCCCCCC
>Mature Secondary Structure 
SAALFEHAKGKLVGVGTGPGDPELLTLKAVRAIENADVLAFFCKKGSAGNGRGIVEAFI
CCCHHHCCCCCEEEEECCCCCCCEEEHHHHHHHCCCCEEEEEECCCCCCCCCCHHEEEE
RPGTLEMPLVYPVTVESDKNGEDYRGAIAAFFDQSAKDIAVHLDAGRNVAVLSEGDPLFY
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCEEE
GSYMHLHLRLAPSYEAEVVAGITAMSGCWSMAGLPLVQGDDILSVLPGTLAEEVLAERLS
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHCCHHHHHHHHHHHHC
GTDGAVIMKVGRNLPKIRRALEVAGKLEEALYVERGTMANSHAVRLIERDASPAPYFSLV
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCCEEEEE
LVPGWKTRPAGSEGS
EECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]