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The map label for this gene is cobM [H]

Identifier: 15890043

GI number: 15890043

Start: 2798280

End: 2799053

Strand: Reverse

Name: cobM [H]

Synonym: Atu2796

Alternate gene names: 15890043

Gene position: 2799053-2798280 (Counterclockwise)

Preceding gene: 15890044

Following gene: 159185385

Centisome position: 98.5

GC content: 62.66

Gene sequence:

>774_bases
ATGACGGTTCATTTCATCGGCGCCGGTCCGGGCGCCGCCGATCTCATCACGGTGCGCGGGCGCGATCTTATCGCGGCCTG
CCCAGTCTGCCTTTACGCCGGTTCGCTGGTTCCGAAGGCCTTGATCGATTATTGCCCGCCGGGTGCACGCATTGTCGATA
CGGCAGCACTTTCGCTTGACGAGATCGAGGCGGAGTTCGTGGCGGCCGCCAAGGCCGGTAAGGATGTCGCGCGGTTGCAT
TCCGGCGATCTTTCGATCTGGAGCGCCATGGGCGAGCAGATCCGCCGCCTGGAGCGCCTGGGTCTCGATTATACCGTCAC
CCCCGGTGTGCCCTCCTTCGCTGCCGCTGCTGCCACCCTGCAGCGGGAGCTGACGGTGCCGGAAATGGCGCAGAGCCTAG
TGCTGACCCGTATTTCCGGCCGCGCTTCAAAAATGCCTGAGGGTGAGACGCTGAAGGCTTTTGGCGCGACAGGTGCGACA
CTCGCCATTCATCTCGCCATCCATGCCATCGGCAAGGTGGTGGAGGAACTGACACCGCTTTATGGCTCCGATTGCCCGGT
CGCCATTGTCGTGCGTGCCTCCTGGCCGGATGAACGGATCATTCGTGGCACGCTTTTTGATATCGAGGGCAAGCTTGTGG
CCGAGCCGGTGGAACGTACGGCGCTGATCTTCGTCGGGCATGGTCTGGCCTCAACGGATTTCCGCGAAAGTGCGCTTTAT
AGCGCCGACTATGTACGCCGGTTCCGGTCCCCGAAGGAGGATGGTGCGGGCTGA

Upstream 100 bases:

>100_bases
TCGCGCCACGCCTCGTGGTCGGTGACGTCACTGTGGCTATCGCAATGACGAGTGACGCGCCGCATGGTAGCCGCAGCGCC
ATTGAATACGGAGAACAAGA

Downstream 100 bases:

>100_bases
TGCGACGGCGTGGAGGTGGTGCGCCCCTTGAGTGCACCCTGACGGTCAAACACCAGAATATCGAGCGCGATCGCCGGCGT
CTTCAGTGCCGCGGCGGCGG

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTVHFIGAGPGAADLITVRGRDLIAACPVCLYAGSLVPKALIDYCPPGARIVDTAALSLDEIEAEFVAAAKAGKDVARLH
SGDLSIWSAMGEQIRRLERLGLDYTVTPGVPSFAAAAATLQRELTVPEMAQSLVLTRISGRASKMPEGETLKAFGATGAT
LAIHLAIHAIGKVVEELTPLYGSDCPVAIVVRASWPDERIIRGTLFDIEGKLVAEPVERTALIFVGHGLASTDFRESALY
SADYVRRFRSPKEDGAG

Sequences:

>Translated_257_residues
MTVHFIGAGPGAADLITVRGRDLIAACPVCLYAGSLVPKALIDYCPPGARIVDTAALSLDEIEAEFVAAAKAGKDVARLH
SGDLSIWSAMGEQIRRLERLGLDYTVTPGVPSFAAAAATLQRELTVPEMAQSLVLTRISGRASKMPEGETLKAFGATGAT
LAIHLAIHAIGKVVEELTPLYGSDCPVAIVVRASWPDERIIRGTLFDIEGKLVAEPVERTALIFVGHGLASTDFRESALY
SADYVRRFRSPKEDGAG
>Mature_256_residues
TVHFIGAGPGAADLITVRGRDLIAACPVCLYAGSLVPKALIDYCPPGARIVDTAALSLDEIEAEFVAAAKAGKDVARLHS
GDLSIWSAMGEQIRRLERLGLDYTVTPGVPSFAAAAATLQRELTVPEMAQSLVLTRISGRASKMPEGETLKAFGATGATL
AIHLAIHAIGKVVEELTPLYGSDCPVAIVVRASWPDERIIRGTLFDIEGKLVAEPVERTALIFVGHGLASTDFRESALYS
ADYVRRFRSPKEDGAG

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=232, Percent_Identity=28.448275862069, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322922, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 27242; Mature: 27110

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFIGAGPGAADLITVRGRDLIAACPVCLYAGSLVPKALIDYCPPGARIVDTAALSLD
CEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
EIEAEFVAAAKAGKDVARLHSGDLSIWSAMGEQIRRLERLGLDYTVTPGVPSFAAAAATL
HHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHH
QRELTVPEMAQSLVLTRISGRASKMPEGETLKAFGATGATLAIHLAIHAIGKVVEELTPL
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
YGSDCPVAIVVRASWPDERIIRGTLFDIEGKLVAEPVERTALIFVGHGLASTDFRESALY
CCCCCCEEEEEEECCCCCHHHEEEEEECCCCEECCCCCCEEEEEEECCCCCCCHHHHHHH
SADYVRRFRSPKEDGAG
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TVHFIGAGPGAADLITVRGRDLIAACPVCLYAGSLVPKALIDYCPPGARIVDTAALSLD
EEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
EIEAEFVAAAKAGKDVARLHSGDLSIWSAMGEQIRRLERLGLDYTVTPGVPSFAAAAATL
HHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHH
QRELTVPEMAQSLVLTRISGRASKMPEGETLKAFGATGATLAIHLAIHAIGKVVEELTPL
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
YGSDCPVAIVVRASWPDERIIRGTLFDIEGKLVAEPVERTALIFVGHGLASTDFRESALY
CCCCCCEEEEEEECCCCCHHHEEEEEECCCCEECCCCCCEEEEEEECCCCCCCHHHHHHH
SADYVRRFRSPKEDGAG
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]