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The map label for this gene is mtrA [H]

Identifier: 15890012

GI number: 15890012

Start: 2764213

End: 2764896

Strand: Reverse

Name: mtrA [H]

Synonym: Atu2763

Alternate gene names: 15890012

Gene position: 2764896-2764213 (Counterclockwise)

Preceding gene: 15890014

Following gene: 159185368

Centisome position: 97.3

GC content: 57.16

Gene sequence:

>684_bases
ATGACGGCTCGCACTATCCTTCTGGTGGACGATGACGACGATCTTCGGGAGACGCTGACCGAGCAATTATCTCCCTATGA
GGAATTCTCGCTGTTGAGCGGCGCAAACGCCGCGCAGGCGATGCAGACTGCCAAAACCGCCCAGGTCGATCTTCTGATCA
TGGATGTAGGCCTTCCTGATATGGATGGCCGCGAAGCGGTGAAGCTGTTGCGCAAGGGTGGCTTCAAGGCACCGATAATC
ATGCTCACCGGGCACGACACCGATTCCGATACGATTCTGGGGCTGGAAGCAGGCGCAAACGACTACGTGACGAAGCCGTT
CCGCTTCGCCGTGCTTCTGGCGCGCATCCGGGCGCAACTGCGCCAGTATGAACAGAGTGAGGACGCGGTTTTCACCGTCG
GTCCTTATCAGTTCAAGCCCAGCCAGAAGCTGCTGACGACCGAAGACGGCAAGAAAATCCGTCTCACGGAAAAGGAAGCG
GCGATCATCCGTTATCTCTATCGCGCCGGCAGCACGGTGGTAACGCGCGATGTTCTGCTGGAAGAGGTCTGGGGTTACAA
TTCCGGCGTCACCACGCATACGCTCGAAACGCATGTCTATCGTTTGCGCCAGAAGATCGAACGGGATCCTTCCAACGCCG
AAATCCTGGTGACCGAGAACGGTGGTTACAAGATCGTTCCTTGA

Upstream 100 bases:

>100_bases
GAAGTCATAGCACTTCATCATGTGATGGCAATGGGTTGACCTTTTACCGGCAAATCGCTGAATTGGCTGACGATTAAAGT
AAGAAAGGCTGAGAATCCGA

Downstream 100 bases:

>100_bases
GACCGGGCTCGTTCATAGCCGCAAAGCTCACGCCGCGCCTCCTGAAAGGATGCGCGGCGTTTCAACGTCTTGTATTTTGA
CGACCGATATTGGAAAACCG

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTARTILLVDDDDDLRETLTEQLSPYEEFSLLSGANAAQAMQTAKTAQVDLLIMDVGLPDMDGREAVKLLRKGGFKAPII
MLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQYEQSEDAVFTVGPYQFKPSQKLLTTEDGKKIRLTEKEA
AIIRYLYRAGSTVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIVP

Sequences:

>Translated_227_residues
MTARTILLVDDDDDLRETLTEQLSPYEEFSLLSGANAAQAMQTAKTAQVDLLIMDVGLPDMDGREAVKLLRKGGFKAPII
MLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQYEQSEDAVFTVGPYQFKPSQKLLTTEDGKKIRLTEKEA
AIIRYLYRAGSTVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIVP
>Mature_226_residues
TARTILLVDDDDDLRETLTEQLSPYEEFSLLSGANAAQAMQTAKTAQVDLLIMDVGLPDMDGREAVKLLRKGGFKAPIIM
LTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQYEQSEDAVFTVGPYQFKPSQKLLTTEDGKKIRLTEKEAA
IIRYLYRAGSTVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIVP

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=32.8828828828829, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=33.4782608695652, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=32.3144104803493, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=30.6666666666667, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789402, Length=204, Percent_Identity=29.9019607843137, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=174, Percent_Identity=32.7586206896552, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=28.5087719298246, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=27.7533039647577, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=27.2340425531915, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=33.0143540669856, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=26.431718061674, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787229, Length=200, Percent_Identity=31, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=172, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=28.75, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788521, Length=222, Percent_Identity=26.1261261261261, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25397; Mature: 25266

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTILLVDDDDDLRETLTEQLSPYEEFSLLSGANAAQAMQTAKTAQVDLLIMDVGLPD
CCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCEEEEEEEECCCCC
MDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RQYEQSEDAVFTVGPYQFKPSQKLLTTEDGKKIRLTEKEAAIIRYLYRAGSTVVTRDVLL
HHHCCCCCCEEEECCEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHCCCEEHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIVP
HHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TARTILLVDDDDDLRETLTEQLSPYEEFSLLSGANAAQAMQTAKTAQVDLLIMDVGLPD
CCEEEEEEECCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCEEEEEEEECCCCC
MDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RQYEQSEDAVFTVGPYQFKPSQKLLTTEDGKKIRLTEKEAAIIRYLYRAGSTVVTRDVLL
HHHCCCCCCEEEECCEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHCCCEEHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIVP
HHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]