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The map label for this gene is thiP [H]

Identifier: 15889965

GI number: 15889965

Start: 2697534

End: 2699159

Strand: Reverse

Name: thiP [H]

Synonym: Atu2713

Alternate gene names: 15889965

Gene position: 2699159-2697534 (Counterclockwise)

Preceding gene: 159185343

Following gene: 159185342

Centisome position: 94.99

GC content: 61.07

Gene sequence:

>1626_bases
ATGATGCTGCGTCGCGATTATCGGCGGTCGATCATTTTGGGGACGGCGGCTTTTGCCGCCGTTTTCCTGTTCATGGCGCT
CGCGGTTTTCGCGCTATTGTCCTTTGATGTCGGCGCATCCGCCGCCGGTGTCATGGATGCCTACACACTGCGCATCCTGC
GCTTCACGCTGTACCAGGCGACGTTGTCCACCCTTTTGTCCATTGCTCTTGGCCTGCCCGTCGCTCTGGCGCTCGCCCGG
CGGAAAGAGTTTCCCGGAAGGATCTGGATCATCCGGCTGATGGCGGTGCCGATGGGGCTACCGGTGATCGTCGGTGCCTT
TGGCATCATCACCATCTGGGGTAGGCAGGGTGTGCTGAACAGTGCCCTTGTTTTTGCCGGGGCGGACGAGCCTTTCAGCA
TATACGGACTTTCCGGCATTCTCATCGCTCACGTCTTCTTCAATCTGCCGCTTAGTGTTCGGCTGATGCTGGCGGGCTTG
GAGCGTATTCCGGGGGAATATTGGCGCATGGCGGCAAGTCTCGGCATGGGGCCGGTTTCGGTTTTCCGTTTCATCGAATG
GCCGGCGGTCTCGCGGCTCATTCCCGGCATTGCCGGGCTAGTTTTCATGCTGTGCGCCACCAGTTTCACGCTCGTGCTTC
TTCTCGGCGGCGGGCCGGCGGCGACAACGCTGGAGGTGGCGATCTATCAGGCGCTGCGGTTCGATTTCGATCCGCAGCGG
GCGATTGCGCTTTCGGTTCTGCAGATCGTCCTCACCGCAGTCCTGCTCGGACTCCTTGCCTTTTTGCCATCGCCGGAAGC
GGAAATCTCCTCGCTCGGTCGCAACATCCGCCGTTTCGACGGCAGAACTACAGGCGCGCGGCTGTGGGACGGTGCGGCAA
TCGTTTTTGCCGTTTTCCTGGTCGGGCTGCCGCTTGTCGCCATAGCTGTTTCGGGGCTGCAGGCCGATCTGTCGCGTCTG
CTCATCGCGCCGATCTTCCTGCGTGCCGCGACGACCAGTCTTTTAATCGCCATGCTGTCGGCAATTCTCGTCGTCCTCTG
CTGCATGGCGATCATCGGCGCACGCCAGGCCATCGGCTCCAGACGCCAACTGGCGTGGCCTTTCGGCCTGCTTTCCGCCC
TGCTTGGGGCGGGGTCGTCGCTGGTGCTGCTTGTTCCGCCCGTCGTGCTGGGAAGCGGATGGTTCCTGCTGTTGCGGGTG
TTTGGTGATGTCAGTTTTTATGCACCCGTTCTCGTGGCGCTCATCAATATGCTGATGGCTCTGCCGCTTGCCATGCGGGT
GATGGAGCCGGCCTTCACCAGCCATTTCCTGCGCACTGGCCGCCTTTCCGCCAGTCTCGGGCTTCAGGGCTATTCGCGGC
TGCGGTTTGCCGATCTGCCGGTTCTCTGGCGGCCCATGCTGATGGCGCTTTCTTTTGCCATGGCGCTATCGCTCGGCGAT
CTGGGGGCAGTTGCACTGTTCGGATCGAAAAATTTCGTGACCTTGCCCTGGCTGGTCTACAGCAATATGGGCAGCTATCG
CACCAACGATGCGGCCGGTTATGCCTTCCTCCTCGGTGTCGTTTGCCTGCTGCTTGCAGCAGGCGGTACTTCACGGCAAT
CCCCATCAGCAAGGGCTGGCATATGA

Upstream 100 bases:

>100_bases
TTTCTGATGGATCCCGAAGAGGTGGCGAAGAACCGCAAAGCCTGGATCGACGAATGGCTTTCGGCCATGAGCATGAACTG
AGGAAGAGGCACGCCCGCGC

Downstream 100 bases:

>100_bases
CAGGCGATGATTTTGCCGTTGCGCTGGATAAGATCAGGCTACGGCTCGGAACGCAGAACTTCGATCTCGATTGCACCTTT
CCGCAAGGTCAGGTGACTGC

Product: thiamine transporter membrane protein

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MMLRRDYRRSIILGTAAFAAVFLFMALAVFALLSFDVGASAAGVMDAYTLRILRFTLYQATLSTLLSIALGLPVALALAR
RKEFPGRIWIIRLMAVPMGLPVIVGAFGIITIWGRQGVLNSALVFAGADEPFSIYGLSGILIAHVFFNLPLSVRLMLAGL
ERIPGEYWRMAASLGMGPVSVFRFIEWPAVSRLIPGIAGLVFMLCATSFTLVLLLGGGPAATTLEVAIYQALRFDFDPQR
AIALSVLQIVLTAVLLGLLAFLPSPEAEISSLGRNIRRFDGRTTGARLWDGAAIVFAVFLVGLPLVAIAVSGLQADLSRL
LIAPIFLRAATTSLLIAMLSAILVVLCCMAIIGARQAIGSRRQLAWPFGLLSALLGAGSSLVLLVPPVVLGSGWFLLLRV
FGDVSFYAPVLVALINMLMALPLAMRVMEPAFTSHFLRTGRLSASLGLQGYSRLRFADLPVLWRPMLMALSFAMALSLGD
LGAVALFGSKNFVTLPWLVYSNMGSYRTNDAAGYAFLLGVVCLLLAAGGTSRQSPSARAGI

Sequences:

>Translated_541_residues
MMLRRDYRRSIILGTAAFAAVFLFMALAVFALLSFDVGASAAGVMDAYTLRILRFTLYQATLSTLLSIALGLPVALALAR
RKEFPGRIWIIRLMAVPMGLPVIVGAFGIITIWGRQGVLNSALVFAGADEPFSIYGLSGILIAHVFFNLPLSVRLMLAGL
ERIPGEYWRMAASLGMGPVSVFRFIEWPAVSRLIPGIAGLVFMLCATSFTLVLLLGGGPAATTLEVAIYQALRFDFDPQR
AIALSVLQIVLTAVLLGLLAFLPSPEAEISSLGRNIRRFDGRTTGARLWDGAAIVFAVFLVGLPLVAIAVSGLQADLSRL
LIAPIFLRAATTSLLIAMLSAILVVLCCMAIIGARQAIGSRRQLAWPFGLLSALLGAGSSLVLLVPPVVLGSGWFLLLRV
FGDVSFYAPVLVALINMLMALPLAMRVMEPAFTSHFLRTGRLSASLGLQGYSRLRFADLPVLWRPMLMALSFAMALSLGD
LGAVALFGSKNFVTLPWLVYSNMGSYRTNDAAGYAFLLGVVCLLLAAGGTSRQSPSARAGI
>Mature_541_residues
MMLRRDYRRSIILGTAAFAAVFLFMALAVFALLSFDVGASAAGVMDAYTLRILRFTLYQATLSTLLSIALGLPVALALAR
RKEFPGRIWIIRLMAVPMGLPVIVGAFGIITIWGRQGVLNSALVFAGADEPFSIYGLSGILIAHVFFNLPLSVRLMLAGL
ERIPGEYWRMAASLGMGPVSVFRFIEWPAVSRLIPGIAGLVFMLCATSFTLVLLLGGGPAATTLEVAIYQALRFDFDPQR
AIALSVLQIVLTAVLLGLLAFLPSPEAEISSLGRNIRRFDGRTTGARLWDGAAIVFAVFLVGLPLVAIAVSGLQADLSRL
LIAPIFLRAATTSLLIAMLSAILVVLCCMAIIGARQAIGSRRQLAWPFGLLSALLGAGSSLVLLVPPVVLGSGWFLLLRV
FGDVSFYAPVLVALINMLMALPLAMRVMEPAFTSHFLRTGRLSASLGLQGYSRLRFADLPVLWRPMLMALSFAMALSLGD
LGAVALFGSKNFVTLPWLVYSNMGSYRTNDAAGYAFLLGVVCLLLAAGGTSRQSPSARAGI

Specific function: Part of the ABC transporter complex thiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1786254, Length=468, Percent_Identity=42.9487179487179, Blast_Score=320, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005947 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57819; Mature: 57819

Theoretical pI: Translated: 11.14; Mature: 11.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLRRDYRRSIILGTAAFAAVFLFMALAVFALLSFDVGASAAGVMDAYTLRILRFTLYQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
TLSTLLSIALGLPVALALARRKEFPGRIWIIRLMAVPMGLPVIVGAFGIITIWGRQGVLN
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCC
SALVFAGADEPFSIYGLSGILIAHVFFNLPLSVRLMLAGLERIPGEYWRMAASLGMGPVS
CCEEEECCCCCCEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHH
VFRFIEWPAVSRLIPGIAGLVFMLCATSFTLVLLLGGGPAATTLEVAIYQALRFDFDPQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCHHH
AIALSVLQIVLTAVLLGLLAFLPSPEAEISSLGRNIRRFDGRTTGARLWDGAAIVFAVFL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHH
VGLPLVAIAVSGLQADLSRLLIAPIFLRAATTSLLIAMLSAILVVLCCMAIIGARQAIGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRQLAWPFGLLSALLGAGSSLVLLVPPVVLGSGWFLLLRVFGDVSFYAPVLVALINMLMA
CCCCCCHHHHHHHHHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLAMRVMEPAFTSHFLRTGRLSASLGLQGYSRLRFADLPVLWRPMLMALSFAMALSLGD
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
LGAVALFGSKNFVTLPWLVYSNMGSYRTNDAAGYAFLLGVVCLLLAAGGTSRQSPSARAG
CCEEEEECCCCCEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
I
C
>Mature Secondary Structure
MMLRRDYRRSIILGTAAFAAVFLFMALAVFALLSFDVGASAAGVMDAYTLRILRFTLYQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
TLSTLLSIALGLPVALALARRKEFPGRIWIIRLMAVPMGLPVIVGAFGIITIWGRQGVLN
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCC
SALVFAGADEPFSIYGLSGILIAHVFFNLPLSVRLMLAGLERIPGEYWRMAASLGMGPVS
CCEEEECCCCCCEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHH
VFRFIEWPAVSRLIPGIAGLVFMLCATSFTLVLLLGGGPAATTLEVAIYQALRFDFDPQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCHHH
AIALSVLQIVLTAVLLGLLAFLPSPEAEISSLGRNIRRFDGRTTGARLWDGAAIVFAVFL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHH
VGLPLVAIAVSGLQADLSRLLIAPIFLRAATTSLLIAMLSAILVVLCCMAIIGARQAIGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRQLAWPFGLLSALLGAGSSLVLLVPPVVLGSGWFLLLRVFGDVSFYAPVLVALINMLMA
CCCCCCHHHHHHHHHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLAMRVMEPAFTSHFLRTGRLSASLGLQGYSRLRFADLPVLWRPMLMALSFAMALSLGD
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
LGAVALFGSKNFVTLPWLVYSNMGSYRTNDAAGYAFLLGVVCLLLAAGGTSRQSPSARAG
CCEEEEECCCCCEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA