Click here to switch to the map view.

The map label for this gene is ccmC [H]

Identifier: 15889943

GI number: 15889943

Start: 2672770

End: 2673531

Strand: Direct

Name: ccmC [H]

Synonym: Atu2688

Alternate gene names: 15889943

Gene position: 2672770-2673531 (Clockwise)

Preceding gene: 15889942

Following gene: 159185327

Centisome position: 94.06

GC content: 61.55

Gene sequence:

>762_bases
ATGAACGAGCAGATCTTCACCATCACCAAATTCAGCGATCTCGCCAACCCCACCCGGTTTCTGGCGCTGGCGGCGCGCAT
TCTGCCCTGGCTCGCTGGGCTCACGGCGCTGGTGCTGGCCGCTGGTCTTTATCTCTCCTTCACCACTGACGGTGATTACC
AGCAGGGTTACACCGTGCGCATCATGTATGTGCATGTGCCCTCTGCCTGGCTGGCGATGATGTGTTATTCGGTCATGGCG
GTCTCTGCCATCGGGACGCTCGTCTGGCGTCATCCGCTGGCGGATGTCAGCCACAAGGCCGCCGCCCCCATTGGTGCTGC
CTTCACGCTGATTGCGCTCATCACCGGCTCGCTCTGGGGCAAACCGATGTGGGGCACCTGGTGGGTGTGGGATGCGCGGC
TCACCTCCGTTTTTGTGCTTTTCCTGATGTATCTCGGGCTGATAGCGCTCAACCGCGCCATGGATGACCCATCCAGAGCA
GCCCGTGTCAGCGCCGTGCTGATCCTCGTCGGTTTCGTGAATATTCCGATCATCAAGTTTTCGGTCGAGTGGTGGAATAC
GCTGCACCAGCCGGCAAGCGTCATCCGCATGGGCGGTTCCGCCATCGATGCAGAGTTTCTGTGGCCGCTTCTGACCATGG
CGATCGGTTTCACGCTGCTGTTCTTCACCTTGCACATCGCCGCCATGCGCAATGAAATCTGGCGCAGGCGCGTGGCCGCG
CAGCGGCGGCTTGCCGCGCGCATGGCCAACCGGGAGGGCTGA

Upstream 100 bases:

>100_bases
TGGCACTGCGCAATGTTATGGATTGACGAAACCGTGATGGATGATCCCCTGTTGACAGGGATCAATTGCGGGGCGGCCAT
TCTCGGGTTACACAAACGGC

Downstream 100 bases:

>100_bases
GGTGATGACACACGCCTTTTATATCGGCATGTCCTATGCGGCGACCGGCCTTGTCGTTCTCTGTCTCATCGCCTGGGTCG
TCGTTGATGGCCAGGCGCGC

Product: ABC transporter, membrane spanning protein (heme)

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNEQIFTITKFSDLANPTRFLALAARILPWLAGLTALVLAAGLYLSFTTDGDYQQGYTVRIMYVHVPSAWLAMMCYSVMA
VSAIGTLVWRHPLADVSHKAAAPIGAAFTLIALITGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRA
ARVSAVLILVGFVNIPIIKFSVEWWNTLHQPASVIRMGGSAIDAEFLWPLLTMAIGFTLLFFTLHIAAMRNEIWRRRVAA
QRRLAARMANREG

Sequences:

>Translated_253_residues
MNEQIFTITKFSDLANPTRFLALAARILPWLAGLTALVLAAGLYLSFTTDGDYQQGYTVRIMYVHVPSAWLAMMCYSVMA
VSAIGTLVWRHPLADVSHKAAAPIGAAFTLIALITGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRA
ARVSAVLILVGFVNIPIIKFSVEWWNTLHQPASVIRMGGSAIDAEFLWPLLTMAIGFTLLFFTLHIAAMRNEIWRRRVAA
QRRLAARMANREG
>Mature_253_residues
MNEQIFTITKFSDLANPTRFLALAARILPWLAGLTALVLAAGLYLSFTTDGDYQQGYTVRIMYVHVPSAWLAMMCYSVMA
VSAIGTLVWRHPLADVSHKAAAPIGAAFTLIALITGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRA
ARVSAVLILVGFVNIPIIKFSVEWWNTLHQPASVIRMGGSAIDAEFLWPLLTMAIGFTLLFFTLHIAAMRNEIWRRRVAA
QRRLAARMANREG

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=222, Percent_Identity=50.9009009009009, Blast_Score=198, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28260; Mature: 28260

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQIFTITKFSDLANPTRFLALAARILPWLAGLTALVLAAGLYLSFTTDGDYQQGYTVR
CCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEE
IMYVHVPSAWLAMMCYSVMAVSAIGTLVWRHPLADVSHKAAAPIGAAFTLIALITGSLWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCC
KPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRAARVSAVLILVGFVNIPIIKF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEE
SVEWWNTLHQPASVIRMGGSAIDAEFLWPLLTMAIGFTLLFFTLHIAAMRNEIWRRRVAA
EHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLAARMANREG
HHHHHHHHHCCCC
>Mature Secondary Structure
MNEQIFTITKFSDLANPTRFLALAARILPWLAGLTALVLAAGLYLSFTTDGDYQQGYTVR
CCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEE
IMYVHVPSAWLAMMCYSVMAVSAIGTLVWRHPLADVSHKAAAPIGAAFTLIALITGSLWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCC
KPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRAARVSAVLILVGFVNIPIIKF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEE
SVEWWNTLHQPASVIRMGGSAIDAEFLWPLLTMAIGFTLLFFTLHIAAMRNEIWRRRVAA
EHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLAARMANREG
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]