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The map label for this gene is xerC

Identifier: 15889883

GI number: 15889883

Start: 2612267

End: 2613214

Strand: Direct

Name: xerC

Synonym: Atu2628

Alternate gene names: 15889883

Gene position: 2612267-2613214 (Clockwise)

Preceding gene: 159185294

Following gene: 15889884

Centisome position: 91.93

GC content: 63.08

Gene sequence:

>948_bases
ATGGAGTACCGCGTGACCGAAATCCTGACATTTGCCGAACCCGATCTCCTGAACGAGCGCCAGTCCTGGCTCGCCACCCT
TGCCGGCGAGCGCCGCCTTGCCGACAACACCGTCGAGGCCTATGAGCGCGACACGCGCCAGTTTCTGAGATTCCTGACCG
GCTATATCGGCAGGCCCGCGGCCATAAGAGATATAGCCGATCTGCGCCCTGTCGATCTGCGTGCTTTTCTGGCCAACCGG
CGCAAGGAAGGCGCCGGCGCGCGTTCACTCGGCCGGCATCTGGCAGGACTGCGCTCGCTTCTTCATCATCTGCAGAAGAA
AGGTCTCGTCAACGCAGCGGGTGCGACCGCCATGCGCGCGCCAAAACAGCCGAAATCCCTGCCGAAACCGCTCACCGACC
GGCAGGCGCTGAAAATCACCACGGCCGAGGCACAGTTGAATGAAGAACCCTGGATCGCCGCCCGCAATGCCGCGGTCCTT
TCGCTGCTTTATGGCTGCGGGCTGCGCATTTCCGAGGCATTGGGTCTCACGCCAGCCGATTTTCCACCCGGCACCCGCAG
CCTGCGCATCACCGGTAAAGGCAACAAGACGCGGATCGTGCCGCTGCTTGCGGTAGTGACGGAAGCGGTCGATACCTACA
GGAAGCTATGTCCCTATGCTCTGGCCGCGGACGAACCGATGTTCCTGGGCGCACGCGGCGGCAAGCTTCAGCCCGCCATC
ATCCAGCGGGAAATGCAGAAGCTGCGCGGCGCTTTCGGCCTGCCGGAAAACGCCACCCCGCATGCGCTGCGCCATTCCTT
CGCCACCCATCTTCTAGCCGGCGGCGGGGACCTGCGCACCATTCAGGAACTGCTTGGCCATGCGAGCCTCTCCACAACAC
AGGTCTATACCGGCGTCGATACCGCACGACTACTGGAAATCTACGACAACGCCCACCCACGTGCCTGA

Upstream 100 bases:

>100_bases
CGACAGGAAAAAGGAAACCGCCCGGGTGTAGTGGGCGCGCCCGGCAAAGTCCACCTCTTAACCAAATACTGACCATAAGA
GCATAGTTTCGGGGGATGGA

Downstream 100 bases:

>100_bases
AGCAGGAATTGGTTAACCGTAAACATTAACCAGACGTCCAAACCGCCGTTCTATAAACGAACAAGAACCGGATTGGACCG
ATGCACAGCCTGATAAAACC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEYRVTEILTFAEPDLLNERQSWLATLAGERRLADNTVEAYERDTRQFLRFLTGYIGRPAAIRDIADLRPVDLRAFLANR
RKEGAGARSLGRHLAGLRSLLHHLQKKGLVNAAGATAMRAPKQPKSLPKPLTDRQALKITTAEAQLNEEPWIAARNAAVL
SLLYGCGLRISEALGLTPADFPPGTRSLRITGKGNKTRIVPLLAVVTEAVDTYRKLCPYALAADEPMFLGARGGKLQPAI
IQREMQKLRGAFGLPENATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDTARLLEIYDNAHPRA

Sequences:

>Translated_315_residues
MEYRVTEILTFAEPDLLNERQSWLATLAGERRLADNTVEAYERDTRQFLRFLTGYIGRPAAIRDIADLRPVDLRAFLANR
RKEGAGARSLGRHLAGLRSLLHHLQKKGLVNAAGATAMRAPKQPKSLPKPLTDRQALKITTAEAQLNEEPWIAARNAAVL
SLLYGCGLRISEALGLTPADFPPGTRSLRITGKGNKTRIVPLLAVVTEAVDTYRKLCPYALAADEPMFLGARGGKLQPAI
IQREMQKLRGAFGLPENATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDTARLLEIYDNAHPRA
>Mature_315_residues
MEYRVTEILTFAEPDLLNERQSWLATLAGERRLADNTVEAYERDTRQFLRFLTGYIGRPAAIRDIADLRPVDLRAFLANR
RKEGAGARSLGRHLAGLRSLLHHLQKKGLVNAAGATAMRAPKQPKSLPKPLTDRQALKITTAEAQLNEEPWIAARNAAVL
SLLYGCGLRISEALGLTPADFPPGTRSLRITGKGNKTRIVPLLAVVTEAVDTYRKLCPYALAADEPMFLGARGGKLQPAI
IQREMQKLRGAFGLPENATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDTARLLEIYDNAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=299, Percent_Identity=35.4515050167224, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790244, Length=301, Percent_Identity=32.890365448505, Blast_Score=158, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_AGRT5 (Q8UC70)

Other databases:

- EMBL:   AE007869
- PIR:   AC2899
- PIR:   D97674
- RefSeq:   NP_355564.1
- ProteinModelPortal:   Q8UC70
- SMR:   Q8UC70
- STRING:   Q8UC70
- GeneID:   1134666
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2628
- eggNOG:   COG0582
- HOGENOM:   HBG727654
- OMA:   LITEMEN
- ProtClustDB:   PRK00236
- BioCyc:   ATUM176299-1:ATU2628-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34532; Mature: 34532

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: ACT_SITE 169-169 ACT_SITE 193-193 ACT_SITE 261-261 ACT_SITE 264-264 ACT_SITE 287-287 ACT_SITE 296-296

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRVTEILTFAEPDLLNERQSWLATLAGERRLADNTVEAYERDTRQFLRFLTGYIGRPA
CCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AIRDIADLRPVDLRAFLANRRKEGAGARSLGRHLAGLRSLLHHLQKKGLVNAAGATAMRA
HHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
PKQPKSLPKPLTDRQALKITTAEAQLNEEPWIAARNAAVLSLLYGCGLRISEALGLTPAD
CCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEHHHHHHHHHHHCCCHHHHHHCCCCCC
FPPGTRSLRITGKGNKTRIVPLLAVVTEAVDTYRKLCPYALAADEPMFLGARGGKLQPAI
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEECCCCCCCHHH
IQREMQKLRGAFGLPENATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVD
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHEECCCH
TARLLEIYDNAHPRA
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MEYRVTEILTFAEPDLLNERQSWLATLAGERRLADNTVEAYERDTRQFLRFLTGYIGRPA
CCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AIRDIADLRPVDLRAFLANRRKEGAGARSLGRHLAGLRSLLHHLQKKGLVNAAGATAMRA
HHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
PKQPKSLPKPLTDRQALKITTAEAQLNEEPWIAARNAAVLSLLYGCGLRISEALGLTPAD
CCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEHHHHHHHHHHHCCCHHHHHHCCCCCC
FPPGTRSLRITGKGNKTRIVPLLAVVTEAVDTYRKLCPYALAADEPMFLGARGGKLQPAI
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEECCCCCCCHHH
IQREMQKLRGAFGLPENATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVD
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHEECCCH
TARLLEIYDNAHPRA
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194