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The map label for this gene is chvH

Identifier: 15889812

GI number: 15889812

Start: 2527094

End: 2527663

Strand: Reverse

Name: chvH

Synonym: Atu2553

Alternate gene names: 15889812

Gene position: 2527663-2527094 (Counterclockwise)

Preceding gene: 159185266

Following gene: 159185260

Centisome position: 88.95

GC content: 57.72

Gene sequence:

>570_bases
ATGGTCAAGGTTATCGCCTCATCTGTCCGCAAGGGCAATGTTCTCGACGTGGACGGCAAGCTTTACGTCGTTCTCACCGC
GCAGAACTTCCACCCGGGCAAGGGTACGCCGGTCACGCAGGTGGACATGCGCCGCATCGTTGATGGCACGAAGGTCTCCG
AGCGCTGGCGCACCACCGAGCAGGTCGAGCGGGCTTTCGTCGAGGACCTGAACTTCCAGTTCCTTTATGAAGATGGCGAA
GGCTTCCACTTCATGAACCCTGAGAACTACGATCAGGTCGTGGTCGATGTCGAGACGATGGGTGACCAGAAGGCCTATCT
GCAGGAAGGCATGACCTGCGTTCTTTCCATTCACGAAGGCAATCCGCTGGCTGTCGAACTGCCGCGTCATGTCACGCTGG
AAATCGTGGAAACGGAACCGGTTGTGAAGGGCCAGACGGCTTCTTCTTCCTACAAGCCGGCAATTCTCTCCAATGGCATC
CGCACGATGGTTCCGCCGCATATCGATGCCGGCATCCGCGTGGTCATCGCAACGGAAGACAATTCCTACGTCGAGCGCGC
CAAGAACTGA

Upstream 100 bases:

>100_bases
TAAGGTAGTTGCGCCCCAGAAAAAAGACAAAACGTCTGCCGGGGCCGGTGCTGCCGCGCAGTCCTTTACGACGCATTTCA
TCGAGTTACAAGGAAGTCAT

Downstream 100 bases:

>100_bases
GCCTGAAGGCTGGGTAAGCACAAAGCACCGGGCGACCGGTGCTTTTTTTATTTTGTGACGTGAAATAACAAAAAGCCCGC
GTCGAAACGCGGGCTCTTTG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRIVDGTKVSERWRTTEQVERAFVEDLNFQFLYEDGE
GFHFMNPENYDQVVVDVETMGDQKAYLQEGMTCVLSIHEGNPLAVELPRHVTLEIVETEPVVKGQTASSSYKPAILSNGI
RTMVPPHIDAGIRVVIATEDNSYVERAKN

Sequences:

>Translated_189_residues
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRIVDGTKVSERWRTTEQVERAFVEDLNFQFLYEDGE
GFHFMNPENYDQVVVDVETMGDQKAYLQEGMTCVLSIHEGNPLAVELPRHVTLEIVETEPVVKGQTASSSYKPAILSNGI
RTMVPPHIDAGIRVVIATEDNSYVERAKN
>Mature_189_residues
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRIVDGTKVSERWRTTEQVERAFVEDLNFQFLYEDGE
GFHFMNPENYDQVVVDVETMGDQKAYLQEGMTCVLSIHEGNPLAVELPRHVTLEIVETEPVVKGQTASSSYKPAILSNGI
RTMVPPHIDAGIRVVIATEDNSYVERAKN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=36.1702127659575, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082061, Length=186, Percent_Identity=32.7956989247312, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_AGRT5 (P0A3B5)

Other databases:

- EMBL:   AE007869
- PIR:   AH2889
- PIR:   E97665
- RefSeq:   NP_355493.1
- ProteinModelPortal:   P0A3B5
- SMR:   P0A3B5
- STRING:   P0A3B5
- GeneID:   1134591
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2553
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- PhylomeDB:   P0A3B5
- ProtClustDB:   PRK00529
- BioCyc:   ATUM176299-1:ATU2553-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21106; Mature: 21106

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRIVDGTKVSERWRTTE
CEEEEECCCCCCCEEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCHH
QVERAFVEDLNFQFLYEDGEGFHFMNPENYDQVVVDVETMGDQKAYLQEGMTCVLSIHEG
HHHHHHHHCCCEEEEEECCCCEEECCCCCCCEEEEEEECCCCHHHHHHCCCEEEEEEECC
NPLAVELPRHVTLEIVETEPVVKGQTASSSYKPAILSNGIRTMVPPHIDAGIRVVIATED
CEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECC
NSYVERAKN
CHHHHHCCC
>Mature Secondary Structure
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRIVDGTKVSERWRTTE
CEEEEECCCCCCCEEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCHH
QVERAFVEDLNFQFLYEDGEGFHFMNPENYDQVVVDVETMGDQKAYLQEGMTCVLSIHEG
HHHHHHHHCCCEEEEEECCCCEEECCCCCCCEEEEEEECCCCHHHHHHCCCEEEEEEECC
NPLAVELPRHVTLEIVETEPVVKGQTASSSYKPAILSNGIRTMVPPHIDAGIRVVIATED
CEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECC
NSYVERAKN
CHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194