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The map label for this gene is gguB [H]

Identifier: 15889623

GI number: 15889623

Start: 2322833

End: 2324029

Strand: Reverse

Name: gguB [H]

Synonym: Atu2346

Alternate gene names: 15889623

Gene position: 2324029-2322833 (Counterclockwise)

Preceding gene: 159185166

Following gene: 15889622

Centisome position: 81.79

GC content: 59.15

Gene sequence:

>1197_bases
ATGAGTTCGGCAAACACCACAAACGAAGAAAGCAACGTCATCTCGGTCGGGTCGTATATTCGATCCAATATCCGCGAATA
CGGCATGCTGATCGCGCTCGTCGCCATCATGGTTTTCTTCCAGTTCTACACCGGCGGCATCCTGTTCCGCCCTGTGAACC
TGACCAACCTCATCCTGCAGAACTCGTTCATCGTCATCATGGCGCTTGGCATGCTGCTCGTCATCGTGGCCGGGCATATC
GACCTTTCGGTCGGTTCCATCGTCGCCTTCGTCGGCGCGATCGCGGCCATATTGACCGTGCAATGGGGCATGAACCCGTT
TCTGGCGGCGCTGATTTGTCTCGTCATCGGCGGCATCATCGGTGCTGCCCAGGGTTACTGGATCGCCTATCACCGCATTC
CGTCGTTCATCGTGACGCTGGCGGGCATGCTGGTGTTCCGCGGCCTGACGCTTTTCGTGCTCGGCGGCAAGAATATCGGT
CCTTTCCCGACCGATTTCCAGGTCATCAGCACCGGCTTCCTGCCTGATATCGGCGGCATCGAAGGTCTGAACACCACGTC
GATGATCCTGACCGTGCTGATTACGGTCGCGCTGTTCTATCTGGCGTGGCGCCGTCGCGTGGTGAACGTGAAGCATGGCA
TCGACGTGGAGCCGTTCGGTTTCTTCATCGTGCAGAATCTGCTGATCTCCGGCGCTATCCTGTTCCTGGGTTACCAGCTG
TCGACCTATCGTGGCCTGCCGAACGTTCTGATCGTGATGCTGGTTCTGATCGCGCTTTACAGCTTCGTGACGCGCCGCAC
GACCATCGGCCGTCGCGTTTACGCCATGGGCGGCAATGAGAAGGCGACCAAGCTTTCCGGTATCAACACCGAACGCCTGA
GCTTCCTCACCTTCGTCAACATGGGCGTGCTGGCCGGTCTTGCCGGCATGATCATCGCGACCCGCCTCAACTCGGCGACG
CCGAAGGCAGGCGTGGGCTTCGAGCTTGACGTGATCGCGGCCTGCTTCATCGGCGGTGCTTCGGCCTCCGGCGGCGTTGG
CAAGATCACCGGGGCCGTTATCGGCGCCTTCATCATGGGTGTGATGAATAACGGCATGTCGATCGTCGGTCTCGGCATCG
ATTTCCAGCAGATGGTCAAGGGCCTCGTGCTGCTCGCCGCTGTGTTCTTCGACGTCTACAACAAGAACAAGGGCTGA

Upstream 100 bases:

>100_bases
ACGTCATGAACGAAGGCCGCATCGTCGCTGAATTGCCGAAGGGAGAGGCGAGCCAGGAAAGCATCATGCGCGCTATCATG
CGCTCAGGGGAGAAGAACTC

Downstream 100 bases:

>100_bases
TCGGCCCAACTCCTATCGCAGTCAAAAAAGTGGCCGGTTTCCGGCCACTTTCATAAGATGCAGGTGCAATGCACCGCGTA
GAAGAGACAAGGCGCATTGC

Product: ABC transporter, membrane spanning protein (sugar)

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSSANTTNEESNVISVGSYIRSNIREYGMLIALVAIMVFFQFYTGGILFRPVNLTNLILQNSFIVIMALGMLLVIVAGHI
DLSVGSIVAFVGAIAAILTVQWGMNPFLAALICLVIGGIIGAAQGYWIAYHRIPSFIVTLAGMLVFRGLTLFVLGGKNIG
PFPTDFQVISTGFLPDIGGIEGLNTTSMILTVLITVALFYLAWRRRVVNVKHGIDVEPFGFFIVQNLLISGAILFLGYQL
STYRGLPNVLIVMLVLIALYSFVTRRTTIGRRVYAMGGNEKATKLSGINTERLSFLTFVNMGVLAGLAGMIIATRLNSAT
PKAGVGFELDVIAACFIGGASASGGVGKITGAVIGAFIMGVMNNGMSIVGLGIDFQQMVKGLVLLAAVFFDVYNKNKG

Sequences:

>Translated_398_residues
MSSANTTNEESNVISVGSYIRSNIREYGMLIALVAIMVFFQFYTGGILFRPVNLTNLILQNSFIVIMALGMLLVIVAGHI
DLSVGSIVAFVGAIAAILTVQWGMNPFLAALICLVIGGIIGAAQGYWIAYHRIPSFIVTLAGMLVFRGLTLFVLGGKNIG
PFPTDFQVISTGFLPDIGGIEGLNTTSMILTVLITVALFYLAWRRRVVNVKHGIDVEPFGFFIVQNLLISGAILFLGYQL
STYRGLPNVLIVMLVLIALYSFVTRRTTIGRRVYAMGGNEKATKLSGINTERLSFLTFVNMGVLAGLAGMIIATRLNSAT
PKAGVGFELDVIAACFIGGASASGGVGKITGAVIGAFIMGVMNNGMSIVGLGIDFQQMVKGLVLLAAVFFDVYNKNKG
>Mature_397_residues
SSANTTNEESNVISVGSYIRSNIREYGMLIALVAIMVFFQFYTGGILFRPVNLTNLILQNSFIVIMALGMLLVIVAGHID
LSVGSIVAFVGAIAAILTVQWGMNPFLAALICLVIGGIIGAAQGYWIAYHRIPSFIVTLAGMLVFRGLTLFVLGGKNIGP
FPTDFQVISTGFLPDIGGIEGLNTTSMILTVLITVALFYLAWRRRVVNVKHGIDVEPFGFFIVQNLLISGAILFLGYQLS
TYRGLPNVLIVMLVLIALYSFVTRRTTIGRRVYAMGGNEKATKLSGINTERLSFLTFVNMGVLAGLAGMIIATRLNSATP
KAGVGFELDVIAACFIGGASASGGVGKITGAVIGAFIMGVMNNGMSIVGLGIDFQQMVKGLVLLAAVFFDVYNKNKG

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=402, Percent_Identity=38.3084577114428, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1790191, Length=379, Percent_Identity=33.245382585752, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI145693152, Length=161, Percent_Identity=38.5093167701863, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788896, Length=150, Percent_Identity=39.3333333333333, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790524, Length=157, Percent_Identity=38.8535031847134, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693214, Length=342, Percent_Identity=28.9473684210526, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082395, Length=100, Percent_Identity=44, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787793, Length=138, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788471, Length=160, Percent_Identity=35.625, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 42436; Mature: 42305

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSANTTNEESNVISVGSYIRSNIREYGMLIALVAIMVFFQFYTGGILFRPVNLTNLILQ
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
NSFIVIMALGMLLVIVAGHIDLSVGSIVAFVGAIAAILTVQWGMNPFLAALICLVIGGII
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GAAQGYWIAYHRIPSFIVTLAGMLVFRGLTLFVLGGKNIGPFPTDFQVISTGFLPDIGGI
HHCCCCEEHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHCCCCCCCCCC
EGLNTTSMILTVLITVALFYLAWRRRVVNVKHGIDVEPFGFFIVQNLLISGAILFLGYQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
STYRGLPNVLIVMLVLIALYSFVTRRTTIGRRVYAMGGNEKATKLSGINTERLSFLTFVN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCHHHHHHHHHHH
MGVLAGLAGMIIATRLNSATPKAGVGFELDVIAACFIGGASASGGVGKITGAVIGAFIMG
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VMNNGMSIVGLGIDFQQMVKGLVLLAAVFFDVYNKNKG
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSANTTNEESNVISVGSYIRSNIREYGMLIALVAIMVFFQFYTGGILFRPVNLTNLILQ
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
NSFIVIMALGMLLVIVAGHIDLSVGSIVAFVGAIAAILTVQWGMNPFLAALICLVIGGII
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GAAQGYWIAYHRIPSFIVTLAGMLVFRGLTLFVLGGKNIGPFPTDFQVISTGFLPDIGGI
HHCCCCEEHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHCCCCCCCCCC
EGLNTTSMILTVLITVALFYLAWRRRVVNVKHGIDVEPFGFFIVQNLLISGAILFLGYQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
STYRGLPNVLIVMLVLIALYSFVTRRTTIGRRVYAMGGNEKATKLSGINTERLSFLTFVN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCHHHHHHHHHHH
MGVLAGLAGMIIATRLNSATPKAGVGFELDVIAACFIGGASASGGVGKITGAVIGAFIMG
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VMNNGMSIVGLGIDFQQMVKGLVLLAAVFFDVYNKNKG
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]