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The map label for this gene is adeC

Identifier: 15889568

GI number: 15889568

Start: 2266028

End: 2267755

Strand: Direct

Name: adeC

Synonym: Atu2292

Alternate gene names: 15889568

Gene position: 2266028-2267755 (Clockwise)

Preceding gene: 159185143

Following gene: 159185147

Centisome position: 79.75

GC content: 58.8

Gene sequence:

>1728_bases
ATGGCAATAATACCAGGAGTCGAACAGAAGCCCATGAGTTCCAATTTAGAATCACGCATCGATCAGGGTACCGGCCGTGA
ACCGGCAGATATGGTTCTGAAGGGCGGGCGTTTTTTCGATCTTGTCACCGGGGAACTTGTTGCTTCGGACATTGCTATTT
GCGGCGATACTGTCGTTGGCACATGTGGAGACTACAAGGGTCGGCATGAAATCGATATTTCCGGAAAAATCGTCGTTCCC
GGCTTCATCGATACACATCTCCATATCGAATCCTCGCTCGTTACACCGCATGAATTCGACCGCTGCGTTCTGCCCTATGG
TGTCACCACCGCCATCTGTGACCCGCACGAGATTGCCAATGTGCTGGGCGCGGAAGGGCTTCAGTTCTTCCTCGACAGCG
CCATGGAAACCATCATGGACATCCGCGTGCAGCTCTCCTCCTGCGTGCCCGCCACCCATCTGGAAACATCAGGCGCCGAT
CTACCGATCGAAAAGCTGCTGCCGTTCCGAAATCATCCGAAGGTCATCGGGCTTGCCGAATTCATGAATTTCCCGGGTGT
CATCCACAAGGACCCGGTGTGCATGGCAAAGCTGGAGGCCTTTCAGGGCCAGCATATCGATGGTCACGCACCGCTTCTGT
CGGGAGCGGCGCTCAACGGTTATCTCGCCGCCGGCATCCGTACCGAACATGAATGCACGAGCGCCGCTGAGGCGCTGGAG
AAAATCCGTAAGGGCATGCATATTCTGGTACGCGAAGGTTCGGTCTCGAAGGACCTGCATGCGCTGATGCCTATCATCAC
CGAACGCCTGTCACCCTATCTGGCGCTCTGCACCGATGATCGCAATCCGCTCGATATCGCCGAACAGGGCCATCTGGACT
ATATGATCCGCACGGCGATCGCCAGCGGCGTGGAACCGCTCGCCATCTATCGAGCCGCCTCGATTTCCGCTGCTAAAGCC
TTCGGTCTTCGTGATCGCGGTCTTGTCGCCCCCGGCTGGCGCGCCGATCTCGTGGTCATCGACACCCTGCAGAACTGTAA
GGCGAGCATGGTGCTTTCCGGCGGCCGCCTGGTCGATGACGCCCTGTTTGCCACCCGCAAACCGGTGGCACCCGTCGGTC
TCGACAGCGTCAAGGCCAGACCGGTGCTTGCCTCCCATTTCGGTGTGCCGGTCACGGAGGGCGAAACCCCAGTCATGGGC
GTGCTTCCCGGCAAGATCATCACCGAACATCGCCGCTACAAGCTGCCGACGGATGGCAACCAGACCACCGTCGATCTCGA
AAACGACATCATCAAGGTTGCCGTCATCGAACGTCATGGCAAGAACGGCAATCATGCCAATGGTTTCGTCCAGGGCTTCG
GACTGAAAAAGGGCGCCATCGCCTCCACCGTCGGCCATGACAGCCATAATATCTGCGTCGTCGGCGTGAGCGAAGACGAC
ATGGCGCTGGCCGCCAACCGGCTCGGAGACATCAAGGGTGGTTTCGTGGTGGTGGAAGACGGCCGGGTGACGGGCGAAAT
CGCGCTCCCCGTCGCCGGGCTTATGAGCCTCGAACCTTACGAGACGGTACGCGACACGCTGCACACCCTGCGCAAGGCCG
CCTACGCACTCGGCACCACGCTGGAAGAACCCTTCCTGCAGGTCGCCTTCCTGCCGCTGCCCGTCATTCCGCATTTGAAG
ATTTCGGATATGGGTATGGTGGATGTGGATCGGTTTGCGCTGATTTGA

Upstream 100 bases:

>100_bases
GAATATGAAAATTTTTTACTATAGCTATATTTAAAAACCACGAAAACGCGAAGAAATAGGCTGAAAACAACCCAAGAATG
CAAATGAAAGAAAATATCGC

Downstream 100 bases:

>100_bases
TTGCGCAGCGTATATCGCCGCACGCGGCGGAGACGTCTAGAGCATTTCGAGGAAAGTGGATCCCGGTCTTCCGGCCGAAA
ATGCTCCAACCGTCTTCGCA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 1; Adenine aminase 1

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MAIIPGVEQKPMSSNLESRIDQGTGREPADMVLKGGRFFDLVTGELVASDIAICGDTVVGTCGDYKGRHEIDISGKIVVP
GFIDTHLHIESSLVTPHEFDRCVLPYGVTTAICDPHEIANVLGAEGLQFFLDSAMETIMDIRVQLSSCVPATHLETSGAD
LPIEKLLPFRNHPKVIGLAEFMNFPGVIHKDPVCMAKLEAFQGQHIDGHAPLLSGAALNGYLAAGIRTEHECTSAAEALE
KIRKGMHILVREGSVSKDLHALMPIITERLSPYLALCTDDRNPLDIAEQGHLDYMIRTAIASGVEPLAIYRAASISAAKA
FGLRDRGLVAPGWRADLVVIDTLQNCKASMVLSGGRLVDDALFATRKPVAPVGLDSVKARPVLASHFGVPVTEGETPVMG
VLPGKIITEHRRYKLPTDGNQTTVDLENDIIKVAVIERHGKNGNHANGFVQGFGLKKGAIASTVGHDSHNICVVGVSEDD
MALAANRLGDIKGGFVVVEDGRVTGEIALPVAGLMSLEPYETVRDTLHTLRKAAYALGTTLEEPFLQVAFLPLPVIPHLK
ISDMGMVDVDRFALI

Sequences:

>Translated_575_residues
MAIIPGVEQKPMSSNLESRIDQGTGREPADMVLKGGRFFDLVTGELVASDIAICGDTVVGTCGDYKGRHEIDISGKIVVP
GFIDTHLHIESSLVTPHEFDRCVLPYGVTTAICDPHEIANVLGAEGLQFFLDSAMETIMDIRVQLSSCVPATHLETSGAD
LPIEKLLPFRNHPKVIGLAEFMNFPGVIHKDPVCMAKLEAFQGQHIDGHAPLLSGAALNGYLAAGIRTEHECTSAAEALE
KIRKGMHILVREGSVSKDLHALMPIITERLSPYLALCTDDRNPLDIAEQGHLDYMIRTAIASGVEPLAIYRAASISAAKA
FGLRDRGLVAPGWRADLVVIDTLQNCKASMVLSGGRLVDDALFATRKPVAPVGLDSVKARPVLASHFGVPVTEGETPVMG
VLPGKIITEHRRYKLPTDGNQTTVDLENDIIKVAVIERHGKNGNHANGFVQGFGLKKGAIASTVGHDSHNICVVGVSEDD
MALAANRLGDIKGGFVVVEDGRVTGEIALPVAGLMSLEPYETVRDTLHTLRKAAYALGTTLEEPFLQVAFLPLPVIPHLK
ISDMGMVDVDRFALI
>Mature_574_residues
AIIPGVEQKPMSSNLESRIDQGTGREPADMVLKGGRFFDLVTGELVASDIAICGDTVVGTCGDYKGRHEIDISGKIVVPG
FIDTHLHIESSLVTPHEFDRCVLPYGVTTAICDPHEIANVLGAEGLQFFLDSAMETIMDIRVQLSSCVPATHLETSGADL
PIEKLLPFRNHPKVIGLAEFMNFPGVIHKDPVCMAKLEAFQGQHIDGHAPLLSGAALNGYLAAGIRTEHECTSAAEALEK
IRKGMHILVREGSVSKDLHALMPIITERLSPYLALCTDDRNPLDIAEQGHLDYMIRTAIASGVEPLAIYRAASISAAKAF
GLRDRGLVAPGWRADLVVIDTLQNCKASMVLSGGRLVDDALFATRKPVAPVGLDSVKARPVLASHFGVPVTEGETPVMGV
LPGKIITEHRRYKLPTDGNQTTVDLENDIIKVAVIERHGKNGNHANGFVQGFGLKKGAIASTVGHDSHNICVVGVSEDDM
ALAANRLGDIKGGFVVVEDGRVTGEIALPVAGLMSLEPYETVRDTLHTLRKAAYALGTTLEEPFLQVAFLPLPVIPHLKI
SDMGMVDVDRFALI

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=557, Percent_Identity=40.2154398563734, Blast_Score=406, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC1_AGRT5 (Q7CXF0)

Other databases:

- EMBL:   AE007869
- PIR:   A97635
- PIR:   AC2858
- RefSeq:   NP_355249.1
- ProteinModelPortal:   Q7CXF0
- STRING:   Q7CXF0
- GeneID:   1134330
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2292
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   GKIITEH
- PhylomeDB:   Q7CXF0
- ProtClustDB:   CLSK881576
- BioCyc:   ATUM176299-1:ATU2292-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 61695; Mature: 61564

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIPGVEQKPMSSNLESRIDQGTGREPADMVLKGGRFFDLVTGELVASDIAICGDTVVG
CCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCEEEEHHHHHHHHHHHHCCCCEEE
TCGDYKGRHEIDISGKIVVPGFIDTHLHIESSLVTPHEFDRCVLPYGVTTAICDPHEIAN
CCCCCCCCEEEECCCEEEECCEECCEEEEECCCCCCHHCCCEEECCCCEEECCCHHHHHH
VLGAEGLQFFLDSAMETIMDIRVQLSSCVPATHLETSGADLPIEKLLPFRNHPKVIGLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHCCCCCCCCEEEHHH
FMNFPGVIHKDPVCMAKLEAFQGQHIDGHAPLLSGAALNGYLAAGIRTEHECTSAAEALE
HHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
KIRKGMHILVREGSVSKDLHALMPIITERLSPYLALCTDDRNPLDIAEQGHLDYMIRTAI
HHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCCHHHHHHHHH
ASGVEPLAIYRAASISAAKAFGLRDRGLVAPGWRADLVVIDTLQNCKASMVLSGGRLVDD
HCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCEEEEECCCCCHHH
ALFATRKPVAPVGLDSVKARPVLASHFGVPVTEGETPVMGVLPGKIITEHRRYKLPTDGN
HHHHCCCCCCCCCCCCCCCCCCHHHHCCCEECCCCCCEEEECCCHHHHCCCCEECCCCCC
QTTVDLENDIIKVAVIERHGKNGNHANGFVQGFGLKKGAIASTVGHDSHNICVVGVSEDD
CEEEEECCCEEEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHCCCCCCCEEEEEECCCC
MALAANRLGDIKGGFVVVEDGRVTGEIALPVAGLMSLEPYETVRDTLHTLRKAAYALGTT
HHHHHHHCCCCCCCEEEEECCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
LEEPFLQVAFLPLPVIPHLKISDMGMVDVDRFALI
HHHHHHEEEEECCCCCCCCEECCCCCEECHHHHCC
>Mature Secondary Structure 
AIIPGVEQKPMSSNLESRIDQGTGREPADMVLKGGRFFDLVTGELVASDIAICGDTVVG
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCEEEEHHHHHHHHHHHHCCCCEEE
TCGDYKGRHEIDISGKIVVPGFIDTHLHIESSLVTPHEFDRCVLPYGVTTAICDPHEIAN
CCCCCCCCEEEECCCEEEECCEECCEEEEECCCCCCHHCCCEEECCCCEEECCCHHHHHH
VLGAEGLQFFLDSAMETIMDIRVQLSSCVPATHLETSGADLPIEKLLPFRNHPKVIGLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHCCCCCCCCEEEHHH
FMNFPGVIHKDPVCMAKLEAFQGQHIDGHAPLLSGAALNGYLAAGIRTEHECTSAAEALE
HHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
KIRKGMHILVREGSVSKDLHALMPIITERLSPYLALCTDDRNPLDIAEQGHLDYMIRTAI
HHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCCHHHHHHHHH
ASGVEPLAIYRAASISAAKAFGLRDRGLVAPGWRADLVVIDTLQNCKASMVLSGGRLVDD
HCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCEEEEECCCCCHHH
ALFATRKPVAPVGLDSVKARPVLASHFGVPVTEGETPVMGVLPGKIITEHRRYKLPTDGN
HHHHCCCCCCCCCCCCCCCCCCHHHHCCCEECCCCCCEEEECCCHHHHCCCCEECCCCCC
QTTVDLENDIIKVAVIERHGKNGNHANGFVQGFGLKKGAIASTVGHDSHNICVVGVSEDD
CEEEEECCCEEEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHCCCCCCCEEEEEECCCC
MALAANRLGDIKGGFVVVEDGRVTGEIALPVAGLMSLEPYETVRDTLHTLRKAAYALGTT
HHHHHHHCCCCCCCEEEEECCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
LEEPFLQVAFLPLPVIPHLKISDMGMVDVDRFALI
HHHHHHEEEEECCCCCCCCEECCCCCEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194