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The map label for this gene is nudL [H]

Identifier: 15889527

GI number: 15889527

Start: 2222862

End: 2223494

Strand: Reverse

Name: nudL [H]

Synonym: Atu2251

Alternate gene names: 15889527

Gene position: 2223494-2222862 (Counterclockwise)

Preceding gene: 15889528

Following gene: 159185123

Centisome position: 78.25

GC content: 58.77

Gene sequence:

>633_bases
ATGACAATGACGACACTCAAAGGTTTTACCGCCAGCGATTTCCGCCGCCGGGTGCTGCAGGAAGGTGAGGGCGTGGCCGA
GCGGGAAAATGGCGACCATGTGCTCAATCCGGGCGTGGTGCTTTCTGGCAACGGCATCCGGCTGAAGGATGCCGCCGTGC
TGATACCTGTCATCGACGATGGCAACGATGCGCGGGTGATCTTCACCCAACGCACGGCAACGCTGCGTCAGCATTCCGGT
CAGATTTCCTTTCCGGGCGGCGGCATCGATGCCGAGGACCGCACGCCTGAAGAGGCGGCGTTGCGCGAGACCGAAGAGGA
AATCGGCCTGTCGCGGTCTTTCGTAGAAACGGTTGGACGGCTGCCGGATTACATTTCCGGGACGGGATTTCGTATCAAAC
CGGTGCTGTCGGTCGTCCGCCCCGGTTTTGACCTGACGCTTAATCCCACTGAAGTTGACGAGGTTTTCGAGGTGCCGCTG
TCCTTCCTGATGGACCCGGCCAATCACGGGCGCGGCAGCCGCATCTTTCAGGGGAAGGAGCGGTTTTTCTACGAAATGCC
CTATGGCGAACGTTACATTTGGGGCATTACCGCGGGCATCGTACGAACGATTTACGAGAGGTTTTATACATGA

Upstream 100 bases:

>100_bases
GCGAGGTGGTCGCCGTGGATGGGGTTGAGATGTTCGCGGTGCGCTCGGGCGGGGTGATCTTTCCAGTGATGCCGGCCAAG
GAACTGGAACGGCTTTCGCA

Downstream 100 bases:

>100_bases
ATAGCCTTGCCGGGCAGGACTGGTTCGAAAAACCGGCGCTCAAGCGTATCTTCGCGCTTCTGAATGCCGATGGCGGCGAG
GTGCGGATCGTCGGCGGCGC

Product: MutT family NTP pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTMTTLKGFTASDFRRRVLQEGEGVAERENGDHVLNPGVVLSGNGIRLKDAAVLIPVIDDGNDARVIFTQRTATLRQHSG
QISFPGGGIDAEDRTPEEAALRETEEEIGLSRSFVETVGRLPDYISGTGFRIKPVLSVVRPGFDLTLNPTEVDEVFEVPL
SFLMDPANHGRGSRIFQGKERFFYEMPYGERYIWGITAGIVRTIYERFYT

Sequences:

>Translated_210_residues
MTMTTLKGFTASDFRRRVLQEGEGVAERENGDHVLNPGVVLSGNGIRLKDAAVLIPVIDDGNDARVIFTQRTATLRQHSG
QISFPGGGIDAEDRTPEEAALRETEEEIGLSRSFVETVGRLPDYISGTGFRIKPVLSVVRPGFDLTLNPTEVDEVFEVPL
SFLMDPANHGRGSRIFQGKERFFYEMPYGERYIWGITAGIVRTIYERFYT
>Mature_209_residues
TMTTLKGFTASDFRRRVLQEGEGVAERENGDHVLNPGVVLSGNGIRLKDAAVLIPVIDDGNDARVIFTQRTATLRQHSGQ
ISFPGGGIDAEDRTPEEAALRETEEEIGLSRSFVETVGRLPDYISGTGFRIKPVLSVVRPGFDLTLNPTEVDEVFEVPLS
FLMDPANHGRGSRIFQGKERFFYEMPYGERYIWGITAGIVRTIYERFYT

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=120, Percent_Identity=35, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788115, Length=156, Percent_Identity=35.8974358974359, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536993, Length=141, Percent_Identity=38.2978723404255, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17510677, Length=162, Percent_Identity=31.4814814814815, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859683, Length=155, Percent_Identity=39.3548387096774, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23447; Mature: 23316

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTTLKGFTASDFRRRVLQEGEGVAERENGDHVLNPGVVLSGNGIRLKDAAVLIPVIDD
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCEEEECCCEEEECCEEEEEEEEC
GNDARVIFTQRTATLRQHSGQISFPGGGIDAEDRTPEEAALRETEEEIGLSRSFVETVGR
CCCEEEEEECCHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHC
LPDYISGTGFRIKPVLSVVRPGFDLTLNPTEVDEVFEVPLSFLMDPANHGRGSRIFQGKE
CCHHHCCCCEEHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCC
RFFYEMPYGERYIWGITAGIVRTIYERFYT
CEEEECCCCCEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMTTLKGFTASDFRRRVLQEGEGVAERENGDHVLNPGVVLSGNGIRLKDAAVLIPVIDD
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCEEEECCCEEEECCEEEEEEEEC
GNDARVIFTQRTATLRQHSGQISFPGGGIDAEDRTPEEAALRETEEEIGLSRSFVETVGR
CCCEEEEEECCHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHC
LPDYISGTGFRIKPVLSVVRPGFDLTLNPTEVDEVFEVPLSFLMDPANHGRGSRIFQGKE
CCHHHCCCCEEHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCC
RFFYEMPYGERYIWGITAGIVRTIYERFYT
CEEEECCCCCEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]