Click here to switch to the map view.

The map label for this gene is fbcB [H]

Identifier: 15889514

GI number: 15889514

Start: 2208689

End: 2209972

Strand: Reverse

Name: fbcB [H]

Synonym: Atu2238

Alternate gene names: 15889514

Gene position: 2209972-2208689 (Counterclockwise)

Preceding gene: 159185116

Following gene: 159185115

Centisome position: 77.77

GC content: 58.57

Gene sequence:

>1284_bases
ATGAGTGGCCATTCCAGTTATCAGCCGTCCACCGGCATCGAGAGGTGGATCGATTCGCGGCTTCCCTTGCCGCGCATGAT
CTATGACAGCTTCGTTGCCTATCCTGTCCCGCGTAACCTGAACTATGCCTACACTTTTGGTGCGATGCTTGCCGTCATGC
TGATCGTGCAGATTCTCACCGGCGTCGTGCTGGCCATGCATTATGCGGCCGAAACGACGGTCGCCTTCAATTCCGTCGAA
AAGATCATGCGTGACGTCAACCATGGCTGGCTGCTGCGCTACATGCATGCCAACGGCGCGTCGTTCTTCTTCATCGCGGT
TTACCTGCACATTGCCCGCGGCCTTTATTACGGCTCCTACAAGGCGCCGCGTGAAATCCTCTGGATTCTCGGCTGCGTGA
TCTATCTGCTGATGATGGCGACGGGCTTCATGGGCTACGTGCTTCCCTGGGGCCAGATGTCCTTCTGGGGCGCGACCGTC
ATCACCGGCTTCTTCACGGCTTTCCCGCTCGTGGGTGAATGGATCCAGCAGTTCCTGCTCGGTGGCTTTGCGGTGGACAA
TCCGACGCTCAACCGCTTCTTCGCACTTCACTACCTGCTGCCCTTCATGATTGCCGGTGTCGTCATCCTGCACATCTGGG
CGCTGCATGTGACGGGCCAGACCAACCCGACCGGTGTGGAAGTGAAGAGCAAGACCGATACGGTGCCCTTCACGCCCTAC
GCGACGCTGAAGGATGCGCTCGGCGTTTCGGTGTTCCTCATCGCCTATGCCTGGTTCATCTTCTACATGCCGAACTTCCT
CGGCCACCCTGATAACTACATCATGGCGGATCCGCTGAAGACGCCGGCCCACATCGTGCCGGAGTGGTATTATCTGCCGT
TCTACGCGATGCTGCGCGCCATCACCTTCAATGTTGGGCCGATCGATTCCAAGCTCGGCGGCGTTCTCGTCATGTTCGGC
GCGATCATCGTGCTGTTCTTCCTGCCCTGGCTCGATACGTCGAAGGTTCGCTCCGCCGTCTATCGCCCCTGGTACAAGAT
GTTCTTCTGGCTGTTCGTGGTCAACGCCATCCTGCTCGGCTGGCTGGGTTCACGCCCTGCGGAAGGACTTTATGTCGTCA
TGTCGCAGATCGGCACGCTCTACTATTTCGGTTTCTTCCTCGTCATCATGCCGATCCTCGGTCTGGTCGAAACGCCCCGG
CGTATTCCGAATTCGATTACCGAGGCCGTTCTTGAAAAGAAGGCTGCCAAGACGGGTGCCGCGCCAGCGGCCGCCCAGGT
CTGA

Upstream 100 bases:

>100_bases
GCCGCATACGTAAGGGTCCGGCGCCGCAGAACCTCGCCATCCCGACATTTGCATTCACATCCGATACCGTGATCAAGATC
GGATAAGGGGACAGTTATTC

Downstream 100 bases:

>100_bases
GCGCGAAGGAAGGATGACGACAATGAAGACGCTATTCACGAGCATCGCGCTTTTCGCCGCCATTAGCTGTTCCGCCGCCG
CCTTCGCGGCGGAGGAGAGC

Product: ubiquinol-cytochrome c reductase cytochrome b subunit

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSGHSSYQPSTGIERWIDSRLPLPRMIYDSFVAYPVPRNLNYAYTFGAMLAVMLIVQILTGVVLAMHYAAETTVAFNSVE
KIMRDVNHGWLLRYMHANGASFFFIAVYLHIARGLYYGSYKAPREILWILGCVIYLLMMATGFMGYVLPWGQMSFWGATV
ITGFFTAFPLVGEWIQQFLLGGFAVDNPTLNRFFALHYLLPFMIAGVVILHIWALHVTGQTNPTGVEVKSKTDTVPFTPY
ATLKDALGVSVFLIAYAWFIFYMPNFLGHPDNYIMADPLKTPAHIVPEWYYLPFYAMLRAITFNVGPIDSKLGGVLVMFG
AIIVLFFLPWLDTSKVRSAVYRPWYKMFFWLFVVNAILLGWLGSRPAEGLYVVMSQIGTLYYFGFFLVIMPILGLVETPR
RIPNSITEAVLEKKAAKTGAAPAAAQV

Sequences:

>Translated_427_residues
MSGHSSYQPSTGIERWIDSRLPLPRMIYDSFVAYPVPRNLNYAYTFGAMLAVMLIVQILTGVVLAMHYAAETTVAFNSVE
KIMRDVNHGWLLRYMHANGASFFFIAVYLHIARGLYYGSYKAPREILWILGCVIYLLMMATGFMGYVLPWGQMSFWGATV
ITGFFTAFPLVGEWIQQFLLGGFAVDNPTLNRFFALHYLLPFMIAGVVILHIWALHVTGQTNPTGVEVKSKTDTVPFTPY
ATLKDALGVSVFLIAYAWFIFYMPNFLGHPDNYIMADPLKTPAHIVPEWYYLPFYAMLRAITFNVGPIDSKLGGVLVMFG
AIIVLFFLPWLDTSKVRSAVYRPWYKMFFWLFVVNAILLGWLGSRPAEGLYVVMSQIGTLYYFGFFLVIMPILGLVETPR
RIPNSITEAVLEKKAAKTGAAPAAAQV
>Mature_426_residues
SGHSSYQPSTGIERWIDSRLPLPRMIYDSFVAYPVPRNLNYAYTFGAMLAVMLIVQILTGVVLAMHYAAETTVAFNSVEK
IMRDVNHGWLLRYMHANGASFFFIAVYLHIARGLYYGSYKAPREILWILGCVIYLLMMATGFMGYVLPWGQMSFWGATVI
TGFFTAFPLVGEWIQQFLLGGFAVDNPTLNRFFALHYLLPFMIAGVVILHIWALHVTGQTNPTGVEVKSKTDTVPFTPYA
TLKDALGVSVFLIAYAWFIFYMPNFLGHPDNYIMADPLKTPAHIVPEWYYLPFYAMLRAITFNVGPIDSKLGGVLVMFGA
IIVLFFLPWLDTSKVRSAVYRPWYKMFFWLFVVNAILLGWLGSRPAEGLYVVMSQIGTLYYFGFFLVIMPILGLVETPRR
IPNSITEAVLEKKAAKTGAAPAAAQV

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome b family [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=377, Percent_Identity=45.6233421750663, Blast_Score=336, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6226529, Length=364, Percent_Identity=51.0989010989011, Blast_Score=352, Evalue=6e-98,
Organism=Saccharomyces cerevisiae, GI6226532, Length=235, Percent_Identity=51.4893617021277, Blast_Score=249, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6226531, Length=154, Percent_Identity=52.5974025974026, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6226530, Length=127, Percent_Identity=51.9685039370079, Blast_Score=140, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N [H]

EC number: 1.10.2.2

Molecular weight: Translated: 48142; Mature: 48010

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCC
>Mature Secondary Structure 
SGHSSYQPSTGIERWIDSRLPLPRMIYDSFVAYPVPRNLNYAYTFGAMLAVMLIVQILT
CCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVVLAMHYAAETTVAFNSVEKIMRDVNHGWLLRYMHANGASFFFIAVYLHIARGLYYGSY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCC
KAPREILWILGCVIYLLMMATGFMGYVLPWGQMSFWGATVITGFFTAFPLVGEWIQQFLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGFAVDNPTLNRFFALHYLLPFMIAGVVILHIWALHVTGQTNPTGVEVKSKTDTVPFTPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCH
ATLKDALGVSVFLIAYAWFIFYMPNFLGHPDNYIMADPLKTPAHIVPEWYYLPFYAMLRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHCCCHHHHHHHHHHHH
ITFNVGPIDSKLGGVLVMFGAIIVLFFLPWLDTSKVRSAVYRPWYKMFFWLFVVNAILLG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLGSRPAEGLYVVMSQIGTLYYFGFFLVIMPILGLVETPRRIPNSITEAVLEKKAAKTGA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHCCC
APAAAQV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2560136 [H]