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The map label for this gene is ycbL [H]

Identifier: 15889480

GI number: 15889480

Start: 2174222

End: 2174866

Strand: Reverse

Name: ycbL [H]

Synonym: Atu2201

Alternate gene names: 15889480

Gene position: 2174866-2174222 (Counterclockwise)

Preceding gene: 15889485

Following gene: 15889474

Centisome position: 76.54

GC content: 60.0

Gene sequence:

>645_bases
ATGGGAAAGTTGCAGGCGGGCATTATTCCGGTCACGCCATTCGAGCAGAACTGCACCATCCTGTTCGATCAGGATACCAA
GGAAGGCGTCGTCGTTGATCCCGGTGGGGATGTGGACGTCATTCTGCAGGTCGTTGCCGAAAACGGCATCACGCTCAAGG
CAATATGGCTGACGCACGGGCATCTTGACCATGCCGGCGGTGCCGACGAACTGCGCGAAAAGCTTTCCCTGTCGGTCATC
GGGCCGCATGAGCATGACCGGCCGCTGCTGGAGAGGATCGAGGTGCAGGCACAGAAATACGGCATCAGCGGTCTGAAGAA
CGTCGAGCCGGACAGCTGGTTGAAGGATGGTGACAAGGTCTCCTTCGGAGACCACGTCTTTGAGGTCTATCATTGCCCGG
GCCATGCGCCCGGTCATGTCATCTATTACAACCGCGACCAGAACTTCGCCCATGTCGGCGACGTGCTGTTTTCGGGATCG
GTGGGGCGCACCGACCTGCCGGGCGGAAACCACGAGCAATTGATGGCGTCCATTCGCGACAAGCTGCTGCCGCTGGGCGA
CGATGTCGGTTTCATCTGCGGCCATGGCCCGGGCGGGCGGTTGGGTGAGGAACGGCTCAACAACCCCTATCTCAAGGGGC
TTTGA

Upstream 100 bases:

>100_bases
GTGGCCGGGCCGCTGAAAACTGGCATCTTTCCGTCGCCATTGTGCCGCAACCGGTCGCGGGCTATAGGAGGCGGACCCTT
TCAGACAGGAGATACGGGAT

Downstream 100 bases:

>100_bases
ATTGGCCAATAGAGGCCTGCAGGGCGCATAAAAAAACCCGGCATTCCTGCCGGGCTTCAACTAGAAAAGAAAGCCGTTTT
AGGGTCAGCCAGCAATCTGC

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MGKLQAGIIPVTPFEQNCTILFDQDTKEGVVVDPGGDVDVILQVVAENGITLKAIWLTHGHLDHAGGADELREKLSLSVI
GPHEHDRPLLERIEVQAQKYGISGLKNVEPDSWLKDGDKVSFGDHVFEVYHCPGHAPGHVIYYNRDQNFAHVGDVLFSGS
VGRTDLPGGNHEQLMASIRDKLLPLGDDVGFICGHGPGGRLGEERLNNPYLKGL

Sequences:

>Translated_214_residues
MGKLQAGIIPVTPFEQNCTILFDQDTKEGVVVDPGGDVDVILQVVAENGITLKAIWLTHGHLDHAGGADELREKLSLSVI
GPHEHDRPLLERIEVQAQKYGISGLKNVEPDSWLKDGDKVSFGDHVFEVYHCPGHAPGHVIYYNRDQNFAHVGDVLFSGS
VGRTDLPGGNHEQLMASIRDKLLPLGDDVGFICGHGPGGRLGEERLNNPYLKGL
>Mature_213_residues
GKLQAGIIPVTPFEQNCTILFDQDTKEGVVVDPGGDVDVILQVVAENGITLKAIWLTHGHLDHAGGADELREKLSLSVIG
PHEHDRPLLERIEVQAQKYGISGLKNVEPDSWLKDGDKVSFGDHVFEVYHCPGHAPGHVIYYNRDQNFAHVGDVLFSGSV
GRTDLPGGNHEQLMASIRDKLLPLGDDVGFICGHGPGGRLGEERLNNPYLKGL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=203, Percent_Identity=29.5566502463054, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787158, Length=205, Percent_Identity=48.780487804878, Blast_Score=213, Evalue=9e-57,
Organism=Escherichia coli, GI1786406, Length=186, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=191, Percent_Identity=28.2722513089005, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221330176, Length=197, Percent_Identity=26.3959390862944, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23281; Mature: 23149

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLQAGIIPVTPFEQNCTILFDQDTKEGVVVDPGGDVDVILQVVAENGITLKAIWLTHG
CCCCCCCEEECCCCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHCCCCEEEEEEEECC
HLDHAGGADELREKLSLSVIGPHEHDRPLLERIEVQAQKYGISGLKNVEPDSWLKDGDKV
CCCCCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEE
SFGDHVFEVYHCPGHAPGHVIYYNRDQNFAHVGDVLFSGSVGRTDLPGGNHEQLMASIRD
ECCCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
KLLPLGDDVGFICGHGPGGRLGEERLNNPYLKGL
HCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
GKLQAGIIPVTPFEQNCTILFDQDTKEGVVVDPGGDVDVILQVVAENGITLKAIWLTHG
CCCCCCEEECCCCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHCCCCEEEEEEEECC
HLDHAGGADELREKLSLSVIGPHEHDRPLLERIEVQAQKYGISGLKNVEPDSWLKDGDKV
CCCCCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEE
SFGDHVFEVYHCPGHAPGHVIYYNRDQNFAHVGDVLFSGSVGRTDLPGGNHEQLMASIRD
ECCCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
KLLPLGDDVGFICGHGPGGRLGEERLNNPYLKGL
HCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]