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The map label for this gene is aatA [H]

Identifier: 15889474

GI number: 15889474

Start: 2169619

End: 2170821

Strand: Reverse

Name: aatA [H]

Synonym: Atu2196

Alternate gene names: 15889474

Gene position: 2170821-2169619 (Counterclockwise)

Preceding gene: 15889480

Following gene: 159185097

Centisome position: 76.39

GC content: 58.6

Gene sequence:

>1203_bases
ATGGCCTTCCTTGCCGACATTCTCTCCCGCGTAAAGCCATCCGCCACCATCGCCGTTACCCAGAAAGCCCGTGAGCTGAA
AGCCAAGGGTCGCGATGTGATTAGCCTTGGCGCCGGCGAGCCGGATTTCGATACGCCCGATAATATCAAGGAAGCGGCCA
TTGACGCCATCAAGCGCGGCGAAACCAAATACACGCCGGTTTCCGGCATTCCTGAACTGCGCAAGGCGATTGCCGACAAG
TTCAAGCGTGAAAACGGCCTCGACTACAAGCCGGAACAGACAATCGTCGGCACCGGCGGCAAGCAGATCCTCTTCAACGC
CTTCATGGCGACGCTGAACCCCGGTGATGAGGTTGTCATTCCCGCGCCTTACTGGGTCAGCTACCCGGAAATGGTGGCGA
TCTGCGGTGGTACGCCAGTTTTCGTCAACGCCACGCTCGAAGACAATTTCAAGCTGAAGCCGGAAGCACTGGAAAAGGCG
ATCACGCCGAAGACCAAGTGGTTCGTCTTCAACTCGCCTTCCAACCCCTCGGGTGCGGCCTATTCGCATGACGAGCTGAA
GGCGCTGACGGACGTGCTGGTCAAGCATCCGCATGTCTGGGTGCTGACGGACGACATGTATGAGCACCTGACCTATGGCG
ATTTCAAATTCGTCACCCCTGTGGAAGTCGAGCCTTCGCTCTATGACCGGACGTTGACGATGAACGGCGTTTCCAAGGCC
TATGCCATGACTGGCTGGCGTATCGGTTACGCTGCCGGCCCGCTGCCGCTGATCAAGGCCATGGACATGATCCAGGGCCA
GCAGACCTCAGGCGCAAGCTCGATCGCACAGTGGGCAGCTGTCGAAGCTCTGAACGGCACCCAGGATTTCATTCCGGAAA
ACAAGAAGATATTCGAAGGCCGCCGCGATCTCGTCGTTTCCATGCTCAATCAGGCTAAAGGCATCAGCTGCCCGTCACCG
GAAGGTGCATTCTACGTCTACCCGTCCTGCGCCGGCCTGATCGGCAAGACCGCGCCTTCGGGCAAGGTCATCGAGACGGA
TACGGATTTCGTTTCCGAGCTTCTGGAAGCCGAAGGCGTTGCCGTCGTGCAGGGATCGGCTTTCGGCCTTGGCCCGAACT
TCCGCATTTCCTACGCCACGTCGGAAACTCTTCTCGAAGAGGCCTGCAAGCGCATCCAGCGTTTCTGCGCCGATTGCCGC
TGA

Upstream 100 bases:

>100_bases
TTTGACCTTGAAACTATGTCCGTCTTTCGACATAGAAATTGCCGTAGCAGACAAGATTTCCAGCCTCTGCCGATGTCAAC
CCCAATAGGACCGATTAAAA

Downstream 100 bases:

>100_bases
TCGGCCCGCTATATTGTATAAAGAAGCCCGGCAGCGATGCCGGGCTTTTTTCGTTTCGGTCAGAGCCCGAGAAACAGCAG
CATGATGAAGGTGGCGAAGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAFLADILSRVKPSATIAVTQKARELKAKGRDVISLGAGEPDFDTPDNIKEAAIDAIKRGETKYTPVSGIPELRKAIADK
FKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVAICGGTPVFVNATLEDNFKLKPEALEKA
ITPKTKWFVFNSPSNPSGAAYSHDELKALTDVLVKHPHVWVLTDDMYEHLTYGDFKFVTPVEVEPSLYDRTLTMNGVSKA
YAMTGWRIGYAAGPLPLIKAMDMIQGQQTSGASSIAQWAAVEALNGTQDFIPENKKIFEGRRDLVVSMLNQAKGISCPSP
EGAFYVYPSCAGLIGKTAPSGKVIETDTDFVSELLEAEGVAVVQGSAFGLGPNFRISYATSETLLEEACKRIQRFCADCR

Sequences:

>Translated_400_residues
MAFLADILSRVKPSATIAVTQKARELKAKGRDVISLGAGEPDFDTPDNIKEAAIDAIKRGETKYTPVSGIPELRKAIADK
FKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVAICGGTPVFVNATLEDNFKLKPEALEKA
ITPKTKWFVFNSPSNPSGAAYSHDELKALTDVLVKHPHVWVLTDDMYEHLTYGDFKFVTPVEVEPSLYDRTLTMNGVSKA
YAMTGWRIGYAAGPLPLIKAMDMIQGQQTSGASSIAQWAAVEALNGTQDFIPENKKIFEGRRDLVVSMLNQAKGISCPSP
EGAFYVYPSCAGLIGKTAPSGKVIETDTDFVSELLEAEGVAVVQGSAFGLGPNFRISYATSETLLEEACKRIQRFCADCR
>Mature_399_residues
AFLADILSRVKPSATIAVTQKARELKAKGRDVISLGAGEPDFDTPDNIKEAAIDAIKRGETKYTPVSGIPELRKAIADKF
KRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVAICGGTPVFVNATLEDNFKLKPEALEKAI
TPKTKWFVFNSPSNPSGAAYSHDELKALTDVLVKHPHVWVLTDDMYEHLTYGDFKFVTPVEVEPSLYDRTLTMNGVSKAY
AMTGWRIGYAAGPLPLIKAMDMIQGQQTSGASSIAQWAAVEALNGTQDFIPENKKIFEGRRDLVVSMLNQAKGISCPSPE
GAFYVYPSCAGLIGKTAPSGKVIETDTDFVSELLEAEGVAVVQGSAFGLGPNFRISYATSETLLEEACKRIQRFCADCR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=27.6381909547739, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=27.6381909547739, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=27.1317829457364, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=27.1317829457364, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI4507369, Length=390, Percent_Identity=25.8974358974359, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI169881281, Length=394, Percent_Identity=23.0964467005076, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=26.9333333333333, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788627, Length=394, Percent_Identity=28.1725888324873, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=29.5081967213115, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=381, Percent_Identity=29.1338582677165, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=381, Percent_Identity=29.1338582677165, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=26.25, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=23.5602094240838, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=312, Percent_Identity=27.8846153846154, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=385, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573069, Length=360, Percent_Identity=25.5555555555556, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646114, Length=360, Percent_Identity=25.5555555555556, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573067, Length=360, Percent_Identity=25.5555555555556, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573065, Length=360, Percent_Identity=25.5555555555556, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=23.342175066313, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=26.8844221105528, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=26.8844221105528, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=26.8844221105528, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=26.8844221105528, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=26.8844221105528, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=26.8844221105528, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43537; Mature: 43406

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLADILSRVKPSATIAVTQKARELKAKGRDVISLGAGEPDFDTPDNIKEAAIDAIKRG
CCHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
ETKYTPVSGIPELRKAIADKFKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVVI
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPEMVAICGGTPVFVNATLEDNFKLKPEALEKAITPKTKWFVFNSPSNPSGAA
CCCCCCCCHHHEEEECCCEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
YSHDELKALTDVLVKHPHVWVLTDDMYEHLTYGDFKFVTPVEVEPSLYDRTLTMNGVSKA
CCHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCEEEECCCCCCCCHHCCEEEECCCHHH
YAMTGWRIGYAAGPLPLIKAMDMIQGQQTSGASSIAQWAAVEALNGTQDFIPENKKIFEG
HHHCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHH
RRDLVVSMLNQAKGISCPSPEGAFYVYPSCAGLIGKTAPSGKVIETDTDFVSELLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHCCCCCCCCEEECCHHHHHHHHHCCCE
AVVQGSAFGLGPNFRISYATSETLLEEACKRIQRFCADCR
EEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFLADILSRVKPSATIAVTQKARELKAKGRDVISLGAGEPDFDTPDNIKEAAIDAIKRG
CHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
ETKYTPVSGIPELRKAIADKFKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVVI
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPEMVAICGGTPVFVNATLEDNFKLKPEALEKAITPKTKWFVFNSPSNPSGAA
CCCCCCCCHHHEEEECCCEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
YSHDELKALTDVLVKHPHVWVLTDDMYEHLTYGDFKFVTPVEVEPSLYDRTLTMNGVSKA
CCHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCEEEECCCCCCCCHHCCEEEECCCHHH
YAMTGWRIGYAAGPLPLIKAMDMIQGQQTSGASSIAQWAAVEALNGTQDFIPENKKIFEG
HHHCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHH
RRDLVVSMLNQAKGISCPSPEGAFYVYPSCAGLIGKTAPSGKVIETDTDFVSELLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHCCCCCCCCEEECCHHHHHHHHHCCCE
AVVQGSAFGLGPNFRISYATSETLLEEACKRIQRFCADCR
EEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]