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The map label for this gene is tnp [C]

Identifier: 15889390

GI number: 15889390

Start: 2071281

End: 2072819

Strand: Reverse

Name: tnp [C]

Synonym: Atu2107

Alternate gene names: 15889390

Gene position: 2072819-2071281 (Counterclockwise)

Preceding gene: 159185050

Following gene: 17935988

Centisome position: 72.95

GC content: 55.62

Gene sequence:

>1539_bases
ATGTATTCCTACGCAGACAGACTTCGAGCGGTTGAGCTTTATATCCGGCTGGGCAAGCGGCTTAACACGACCATTCGCCA
GCTGGGATATCCCACCAAGAATGCGCTGAGGGGTTGGTATCGCGAGTATGTGCAGCATCTCGACCTGCGTACTCAGCCGG
TAGCGCGAGCGCCAAAATATTCAGAGGCTCAGAGGCAGGCGGCACTTGAGCACTTTCGCACCCATGATCGTTGCATCTCT
GGGACGATGAGGGCGCTCGGCTATCCCGGTCGAGGAACTCTAACCGCATGGGTTCGTGAGGCTTTTCCGGAGGCGCGGAC
ATCAATGGTCGGTCGATCGTGGCACCCTGGCTATTCCGAGGAGGTCCGGCAAGCGGGGGTAATCGGACTATGCAGTGGAG
ATGAAAGTGCTCAGCAGGTAGCTGACCGTCTGGGCGTCTCGAGACCGACATTGTATAGCTGGAAAGACCAGTTACTCGGT
CATGAGGCTTCTTCATCCATGAAACGCCGCAAAGCCAACCCCAAGGTGCCTGAACGTGAAGAACTCGAGCGAAAGCTTGA
AGCCCTCCAACGCGATGTCCGCCAGTTGCAACTCGAACATGATCTCCTGAAAAAGGCCAACGAACTATTAAAAAAAGGTC
TGGGCGTCGATCTGCTGATCCTGAGTAATCGGGAGAAGACACAGCTGATTGACGCCCTCAAGGAAGTTTATCGCTTGCCA
GAGCTGCTTGCCCAACTGCGAATTGCCCGAAGCTCGTACTTCTACCATCGCGCCCGTATGTGCCTGGCAGACAAGTATGC
CGCCGTCCGCCTCAGCCTTGCGGAAATTTTTGAAGCGAACCGTCGTTGTTACGGCTACCGCAGACTACAGGCGTCACTGG
CCAGGAAGAGCGTGATCGTCTCGGAAAAGGTTGTCCAGCGCTTGATGAAGCAGGAGCACTTGGCCGTAGCCAGACCGCGC
CGACGGCGTTTCGGATCATACTTGGGAGAAATAAGTCCGGCACCCGAAAACCTGATCAATCGCGACTTTCATGCAGACGC
GCCGAACGTGAAATGGCTGACAGACATCACCGAGTTCCAGATCCCAGCTGGCAAGGTCTACCTTTCGCCCATCATCGACT
GCTTTGACGGAATGGTCATCAGTTGGTCCATCGGAACCCAACCAGATGCGGGTCTCGTCAACACCATGCTGGATGCAGCC
ATCGGGACCGTCGCCAACGGCGAGGAACGGCCTATCATCCATTCTGATCGAGGAGCCCATTATCGATGGCCCGGCTGGTT
AACCCGTATCAGCGAAGCAAGACTGGTTCGTTCGATGTCCCGAAAGGGATGCTCGCAAGACAACGCCGCGTGCGAAGGGT
TCTTCGGTCGGTTGAAAACTGAGCTCTTCTATCCACGCGACTGGAAGGCAATCACGATCGAACAGTTCGTCGCCGAGGTG
GACGCCTACATCCGATGGTACAATGAGAAGCGTATCAAGATATCGCTGGGATCACTCAGCCCCGTCGAGTATCGTCAGAG
CCTCGGCCTGAAATTATAA

Upstream 100 bases:

>100_bases
AGGTAAATTGTCGTGCCGCAATCTTCGGCGCTGTCGCTCACCGCTGCGAAATGGAAAATCGGGGGTGCGGACGAAAACTT
GGACCACCAGGAGGTAGTTC

Downstream 100 bases:

>100_bases
AGCAGTCCAACTTTTTATCCGCACCCCCATCCTGTCTCGCGAGAATTGCCCAAAGGCCTCGATCAAGGCTTCTTGAACCG
AGTTGAACTGGTCGGTTTGC

Product: IS3 family transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MYSYADRLRAVELYIRLGKRLNTTIRQLGYPTKNALRGWYREYVQHLDLRTQPVARAPKYSEAQRQAALEHFRTHDRCIS
GTMRALGYPGRGTLTAWVREAFPEARTSMVGRSWHPGYSEEVRQAGVIGLCSGDESAQQVADRLGVSRPTLYSWKDQLLG
HEASSSMKRRKANPKVPEREELERKLEALQRDVRQLQLEHDLLKKANELLKKGLGVDLLILSNREKTQLIDALKEVYRLP
ELLAQLRIARSSYFYHRARMCLADKYAAVRLSLAEIFEANRRCYGYRRLQASLARKSVIVSEKVVQRLMKQEHLAVARPR
RRRFGSYLGEISPAPENLINRDFHADAPNVKWLTDITEFQIPAGKVYLSPIIDCFDGMVISWSIGTQPDAGLVNTMLDAA
IGTVANGEERPIIHSDRGAHYRWPGWLTRISEARLVRSMSRKGCSQDNAACEGFFGRLKTELFYPRDWKAITIEQFVAEV
DAYIRWYNEKRIKISLGSLSPVEYRQSLGLKL

Sequences:

>Translated_512_residues
MYSYADRLRAVELYIRLGKRLNTTIRQLGYPTKNALRGWYREYVQHLDLRTQPVARAPKYSEAQRQAALEHFRTHDRCIS
GTMRALGYPGRGTLTAWVREAFPEARTSMVGRSWHPGYSEEVRQAGVIGLCSGDESAQQVADRLGVSRPTLYSWKDQLLG
HEASSSMKRRKANPKVPEREELERKLEALQRDVRQLQLEHDLLKKANELLKKGLGVDLLILSNREKTQLIDALKEVYRLP
ELLAQLRIARSSYFYHRARMCLADKYAAVRLSLAEIFEANRRCYGYRRLQASLARKSVIVSEKVVQRLMKQEHLAVARPR
RRRFGSYLGEISPAPENLINRDFHADAPNVKWLTDITEFQIPAGKVYLSPIIDCFDGMVISWSIGTQPDAGLVNTMLDAA
IGTVANGEERPIIHSDRGAHYRWPGWLTRISEARLVRSMSRKGCSQDNAACEGFFGRLKTELFYPRDWKAITIEQFVAEV
DAYIRWYNEKRIKISLGSLSPVEYRQSLGLKL
>Mature_512_residues
MYSYADRLRAVELYIRLGKRLNTTIRQLGYPTKNALRGWYREYVQHLDLRTQPVARAPKYSEAQRQAALEHFRTHDRCIS
GTMRALGYPGRGTLTAWVREAFPEARTSMVGRSWHPGYSEEVRQAGVIGLCSGDESAQQVADRLGVSRPTLYSWKDQLLG
HEASSSMKRRKANPKVPEREELERKLEALQRDVRQLQLEHDLLKKANELLKKGLGVDLLILSNREKTQLIDALKEVYRLP
ELLAQLRIARSSYFYHRARMCLADKYAAVRLSLAEIFEANRRCYGYRRLQASLARKSVIVSEKVVQRLMKQEHLAVARPR
RRRFGSYLGEISPAPENLINRDFHADAPNVKWLTDITEFQIPAGKVYLSPIIDCFDGMVISWSIGTQPDAGLVNTMLDAA
IGTVANGEERPIIHSDRGAHYRWPGWLTRISEARLVRSMSRKGCSQDNAACEGFFGRLKTELFYPRDWKAITIEQFVAEV
DAYIRWYNEKRIKISLGSLSPVEYRQSLGLKL

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=261, Percent_Identity=28.735632183908, Blast_Score=93, Evalue=7e-19,
Organism=Escherichia coli, GI1789981, Length=279, Percent_Identity=41.2186379928315, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1788405, Length=288, Percent_Identity=30.2083333333333, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787263, Length=288, Percent_Identity=30.2083333333333, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786753, Length=288, Percent_Identity=30.2083333333333, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786570, Length=288, Percent_Identity=30.2083333333333, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786490, Length=288, Percent_Identity=30.2083333333333, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 58784; Mature: 58784

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00019 ACTININ_1 ; PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSYADRLRAVELYIRLGKRLNTTIRQLGYPTKNALRGWYREYVQHLDLRTQPVARAPKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCCH
SEAQRQAALEHFRTHDRCISGTMRALGYPGRGTLTAWVREAFPEARTSMVGRSWHPGYSE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EVRQAGVIGLCSGDESAQQVADRLGVSRPTLYSWKDQLLGHEASSSMKRRKANPKVPERE
HHHHCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
ELERKLEALQRDVRQLQLEHDLLKKANELLKKGLGVDLLILSNREKTQLIDALKEVYRLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
ELLAQLRIARSSYFYHRARMCLADKYAAVRLSLAEIFEANRRCYGYRRLQASLARKSVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEKVVQRLMKQEHLAVARPRRRRFGSYLGEISPAPENLINRDFHADAPNVKWLTDITEFQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEHHHHHHHC
IPAGKVYLSPIIDCFDGMVISWSIGTQPDAGLVNTMLDAAIGTVANGEERPIIHSDRGAH
CCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCC
YRWPGWLTRISEARLVRSMSRKGCSQDNAACEGFFGRLKTELFYPRDWKAITIEQFVAEV
EECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DAYIRWYNEKRIKISLGSLSPVEYRQSLGLKL
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure
MYSYADRLRAVELYIRLGKRLNTTIRQLGYPTKNALRGWYREYVQHLDLRTQPVARAPKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCCH
SEAQRQAALEHFRTHDRCISGTMRALGYPGRGTLTAWVREAFPEARTSMVGRSWHPGYSE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EVRQAGVIGLCSGDESAQQVADRLGVSRPTLYSWKDQLLGHEASSSMKRRKANPKVPERE
HHHHCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
ELERKLEALQRDVRQLQLEHDLLKKANELLKKGLGVDLLILSNREKTQLIDALKEVYRLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
ELLAQLRIARSSYFYHRARMCLADKYAAVRLSLAEIFEANRRCYGYRRLQASLARKSVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEKVVQRLMKQEHLAVARPRRRRFGSYLGEISPAPENLINRDFHADAPNVKWLTDITEFQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEHHHHHHHC
IPAGKVYLSPIIDCFDGMVISWSIGTQPDAGLVNTMLDAAIGTVANGEERPIIHSDRGAH
CCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCC
YRWPGWLTRISEARLVRSMSRKGCSQDNAACEGFFGRLKTELFYPRDWKAITIEQFVAEV
EECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DAYIRWYNEKRIKISLGSLSPVEYRQSLGLKL
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]