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The map label for this gene is murG

Identifier: 15889378

GI number: 15889378

Start: 2057440

End: 2058576

Strand: Reverse

Name: murG

Synonym: Atu2094

Alternate gene names: 15889378

Gene position: 2058576-2057440 (Counterclockwise)

Preceding gene: 15889379

Following gene: 15889377

Centisome position: 72.44

GC content: 63.59

Gene sequence:

>1137_bases
ATGAACAAGGGTATTGTTCTTCTTGCCGCCGGGGGAACCGGCGGCCATGTGTTTCCGGCGGAAGCCCTGGCGCATACGCT
GAAGGCGCGCGGTTATCAGGTGCATCTCGTCACCGACAGCCGCGCCGAACGTTATGCCGGCAAGTTCCCGGCCGATGAAA
TTCACGTCGTGCCTTCAGCCACCATCGGCTCGAAAAACCCGATTTCGGTCGTGCGTTCGCTCTGGAAACTATGGGTGGGC
CTGCGCACCGCGCGCCGGCTGGTGACGAAACTGAAGCCGGTCGCGGTTGTCGGTTTCGGCGGTTATCCCACCGTGCCGCC
GCTGCTGGCCTCGACCGGACTTGGCGTTCCTTCGATCATTCACGAGCAGAATGCGGTTATGGGCCGCGCCAACAAGGCGC
TCGCTGCCCGCGTGAAGGCGATTGCCGGCGGCTTCCTGCCGCCCGCCAACGGCCAATATTCGGAGAAGACGGTTGCGACC
GGCAATCCGGTGCGCCCGGCGGTGCTGGCTGCATCTGAAATTCCCTATACGCCTTCACAGACGGGCGAGACCTTCCAGCT
TGTGGTTTTCGGCGGCAGCCAGGGCGCGCAGTTCTTTTCGAGCGCCGTTCCGGCAGCGATCTGCCTGATGAAGGACGAGC
AGCGCAAACGCATCGTCGTGACCCAGCAGGCGCGCCCCGAAGACAAGGACAGCGTCATCGCCTCCTACCAGAAGCTGGGT
GTGAAGGCTGACGTTTCCCCCTTCTTCGGCGACATGGCCTCACGCATCGGTGAGGCCGATCTCGTCATCAGCCGCTCGGG
CGCCTCGACCGTATCGGAGCTTTCGGTGATCGGCCGTCCGTCGATCCTCGTGCCTTATCCGCATGCGCTGGACCATGATC
AGGCGGCGAATGCGGCAGCGCTTTCGGCAGCCGGCGGGGCAAGCGTCATCAAGCAGGCGGAACTGTCGCCGCAGAAGCTT
TCCAGCCTGTTGTCATCGGCGCTTGCCGAGCCCGACCGGCTTTCTGCCACCGCGGCAGCGGCCAAGGCGACCGGAAAACC
GCATGCGGCGGATGTGCTGGCCGATCTGGTCGAGGCGATTGCCGAAGGCCGGTCCGTACAGGAATTCAAGAAGAAGAATG
AAGGAGTTGGGGCATGA

Upstream 100 bases:

>100_bases
CGGCTTCCTTCTGGCGCTGACACGCCACAGACCGGAAAAGCGGGCGCAGGAGCGCAGCTTCTTCCGCGTCGGTTCCGGCG
TTCCTGCGGAGTAAACGATC

Downstream 100 bases:

>100_bases
AGATGCCGAAAGCCATAGGCCTTGTGCATTTCATCGGCATAGGCGGGATCGGCATGAGCGGCATTGCCGAAGTGCTTCAC
AATCTCGGCCATCGCGTTCA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNKGIVLLAAGGTGGHVFPAEALAHTLKARGYQVHLVTDSRAERYAGKFPADEIHVVPSATIGSKNPISVVRSLWKLWVG
LRTARRLVTKLKPVAVVGFGGYPTVPPLLASTGLGVPSIIHEQNAVMGRANKALAARVKAIAGGFLPPANGQYSEKTVAT
GNPVRPAVLAASEIPYTPSQTGETFQLVVFGGSQGAQFFSSAVPAAICLMKDEQRKRIVVTQQARPEDKDSVIASYQKLG
VKADVSPFFGDMASRIGEADLVISRSGASTVSELSVIGRPSILVPYPHALDHDQAANAAALSAAGGASVIKQAELSPQKL
SSLLSSALAEPDRLSATAAAAKATGKPHAADVLADLVEAIAEGRSVQEFKKKNEGVGA

Sequences:

>Translated_378_residues
MNKGIVLLAAGGTGGHVFPAEALAHTLKARGYQVHLVTDSRAERYAGKFPADEIHVVPSATIGSKNPISVVRSLWKLWVG
LRTARRLVTKLKPVAVVGFGGYPTVPPLLASTGLGVPSIIHEQNAVMGRANKALAARVKAIAGGFLPPANGQYSEKTVAT
GNPVRPAVLAASEIPYTPSQTGETFQLVVFGGSQGAQFFSSAVPAAICLMKDEQRKRIVVTQQARPEDKDSVIASYQKLG
VKADVSPFFGDMASRIGEADLVISRSGASTVSELSVIGRPSILVPYPHALDHDQAANAAALSAAGGASVIKQAELSPQKL
SSLLSSALAEPDRLSATAAAAKATGKPHAADVLADLVEAIAEGRSVQEFKKKNEGVGA
>Mature_378_residues
MNKGIVLLAAGGTGGHVFPAEALAHTLKARGYQVHLVTDSRAERYAGKFPADEIHVVPSATIGSKNPISVVRSLWKLWVG
LRTARRLVTKLKPVAVVGFGGYPTVPPLLASTGLGVPSIIHEQNAVMGRANKALAARVKAIAGGFLPPANGQYSEKTVAT
GNPVRPAVLAASEIPYTPSQTGETFQLVVFGGSQGAQFFSSAVPAAICLMKDEQRKRIVVTQQARPEDKDSVIASYQKLG
VKADVSPFFGDMASRIGEADLVISRSGASTVSELSVIGRPSILVPYPHALDHDQAANAAALSAAGGASVIKQAELSPQKL
SSLLSSALAEPDRLSATAAAAKATGKPHAADVLADLVEAIAEGRSVQEFKKKNEGVGA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=359, Percent_Identity=33.1476323119777, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_AGRT5 (Q8UDM8)

Other databases:

- EMBL:   AE007869
- PIR:   AG2833
- PIR:   C97611
- RefSeq:   NP_355059.1
- ProteinModelPortal:   Q8UDM8
- STRING:   Q8UDM8
- GeneID:   1134132
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2094
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q8UDM8
- ProtClustDB:   PRK00726
- BioCyc:   ATUM176299-1:ATU2094-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39216; Mature: 39216

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKGIVLLAAGGTGGHVFPAEALAHTLKARGYQVHLVTDSRAERYAGKFPADEIHVVPSA
CCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHCCCCCCCCEEEECCC
TIGSKNPISVVRSLWKLWVGLRTARRLVTKLKPVAVVGFGGYPTVPPLLASTGLGVPSII
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCHHHH
HEQNAVMGRANKALAARVKAIAGGFLPPANGQYSEKTVATGNPVRPAVLAASEIPYTPSQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHEECCCCCCCCCC
TGETFQLVVFGGSQGAQFFSSAVPAAICLMKDEQRKRIVVTQQARPEDKDSVIASYQKLG
CCCEEEEEEEECCCCHHHHHHHHHHHEEHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHC
VKADVSPFFGDMASRIGEADLVISRSGASTVSELSVIGRPSILVPYPHALDHDQAANAAA
CCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHH
LSAAGGASVIKQAELSPQKLSSLLSSALAEPDRLSATAAAAKATGKPHAADVLADLVEAI
HHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AEGRSVQEFKKKNEGVGA
HCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MNKGIVLLAAGGTGGHVFPAEALAHTLKARGYQVHLVTDSRAERYAGKFPADEIHVVPSA
CCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHCCCCCCCCEEEECCC
TIGSKNPISVVRSLWKLWVGLRTARRLVTKLKPVAVVGFGGYPTVPPLLASTGLGVPSII
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCHHHH
HEQNAVMGRANKALAARVKAIAGGFLPPANGQYSEKTVATGNPVRPAVLAASEIPYTPSQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHEECCCCCCCCCC
TGETFQLVVFGGSQGAQFFSSAVPAAICLMKDEQRKRIVVTQQARPEDKDSVIASYQKLG
CCCEEEEEEEECCCCHHHHHHHHHHHEEHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHC
VKADVSPFFGDMASRIGEADLVISRSGASTVSELSVIGRPSILVPYPHALDHDQAANAAA
CCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHH
LSAAGGASVIKQAELSPQKLSSLLSSALAEPDRLSATAAAAKATGKPHAADVLADLVEAI
HHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AEGRSVQEFKKKNEGVGA
HCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194