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The map label for this gene is ribB

Identifier: 15889192

GI number: 15889192

Start: 1872469

End: 1873110

Strand: Direct

Name: ribB

Synonym: Atu1895

Alternate gene names: 15889192

Gene position: 1872469-1873110 (Clockwise)

Preceding gene: 15889191

Following gene: 15889197

Centisome position: 65.9

GC content: 60.9

Gene sequence:

>642_bases
ATGACCATTGCTAAAATTGAAGACGCCATCGAAGCCATTTCCCGTGGTGAAATGGTGATTGTGGTTGACGACGAAGACCG
CGAAAATGAAGGCGATATCATCGCCGCCTCCGACAGCATCACGCCGCAGCAGATCGCTTTCATGATGAACCATGCGCGCG
GGCTGGTGTGCGTTGCCATGCCGGGCGAGCGTCTGGATGCGCTCGACATTCCGCTGATGGTGTCGCGCAACACCGAATCC
CTCAAGACGGCCTTCACCGTCTCGGTGGACTATATTCCGGGCACCACGACAGGCATCTCCGCCGCCGACCGGGCAAAGAC
GGTGCGTGCGCTGGTGTCGGAAGGCTCACGCCCGGAAGATTTCGCCCGTCCCGGCCATATCTTCCCGCTCCGCGCTAATC
CGGAAGGCGTTCTCGGCCGCACCGGCCACACGGAAGCAGCCGTAGACCTCTGCCGTCTTGCCGGGAAATTCCCGTCCGGC
ACCATCTGCGAAGTCGCCAACGATGACGGCACCATGGCCCGCCTGCCCCAGCTCGAAATCTTCGCCGAACGCCACGGCCT
GCTCGTCGTGACGATCAAGGACCTCGTTTCCTATCTCAAGGGTGAGGTTGTGGAGGAAATGGTGCAGAAGCAGGTGGCTT
GA

Upstream 100 bases:

>100_bases
GTGGGCTTCGCATTGCATTGTTCGCCCAAGGGATATTTGGCGCTTCTTGAAGCGCGAAAATGCCGCAAACCGGCATAACC
CTTGAAAGGCTTGAAATAAA

Downstream 100 bases:

>100_bases
GCTGCGCAAACCTGTGGTGCGAATACCAAAACGCCCGGCGTAGGCCGGGCGTGAATTTGGAGGCAGACATTACTTTTATG
CGACATCGTCCTCAGACTCT

Product: 3, 4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTIAKIEDAIEAISRGEMVIVVDDEDRENEGDIIAASDSITPQQIAFMMNHARGLVCVAMPGERLDALDIPLMVSRNTES
LKTAFTVSVDYIPGTTTGISAADRAKTVRALVSEGSRPEDFARPGHIFPLRANPEGVLGRTGHTEAAVDLCRLAGKFPSG
TICEVANDDGTMARLPQLEIFAERHGLLVVTIKDLVSYLKGEVVEEMVQKQVA

Sequences:

>Translated_213_residues
MTIAKIEDAIEAISRGEMVIVVDDEDRENEGDIIAASDSITPQQIAFMMNHARGLVCVAMPGERLDALDIPLMVSRNTES
LKTAFTVSVDYIPGTTTGISAADRAKTVRALVSEGSRPEDFARPGHIFPLRANPEGVLGRTGHTEAAVDLCRLAGKFPSG
TICEVANDDGTMARLPQLEIFAERHGLLVVTIKDLVSYLKGEVVEEMVQKQVA
>Mature_212_residues
TIAKIEDAIEAISRGEMVIVVDDEDRENEGDIIAASDSITPQQIAFMMNHARGLVCVAMPGERLDALDIPLMVSRNTESL
KTAFTVSVDYIPGTTTGISAADRAKTVRALVSEGSRPEDFARPGHIFPLRANPEGVLGRTGHTEAAVDLCRLAGKFPSGT
ICEVANDDGTMARLPQLEIFAERHGLLVVTIKDLVSYLKGEVVEEMVQKQVA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=194, Percent_Identity=50.5154639175258, Blast_Score=214, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=46.7980295566502, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_AGRT5 (Q8UE66)

Other databases:

- EMBL:   AE007869
- PIR:   A97588
- PIR:   AE2809
- RefSeq:   NP_354873.1
- ProteinModelPortal:   Q8UE66
- SMR:   Q8UE66
- STRING:   Q8UE66
- GeneID:   1133933
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1895
- eggNOG:   COG0108
- HOGENOM:   HBG735778
- OMA:   CELMNED
- PhylomeDB:   Q8UE66
- ProtClustDB:   CLSK557851
- BioCyc:   ATUM176299-1:ATU1895-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 22977; Mature: 22845

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: BINDING 32-32 BINDING 164-164

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAKIEDAIEAISRGEMVIVVDDEDRENEGDIIAASDSITPQQIAFMMNHARGLVCVAM
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEC
PGERLDALDIPLMVSRNTESLKTAFTVSVDYIPGTTTGISAADRAKTVRALVSEGSRPED
CCCCCCCCCCCEEEECCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
FARPGHIFPLRANPEGVLGRTGHTEAAVDLCRLAGKFPSGTICEVANDDGTMARLPQLEI
HCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCEE
FAERHGLLVVTIKDLVSYLKGEVVEEMVQKQVA
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIAKIEDAIEAISRGEMVIVVDDEDRENEGDIIAASDSITPQQIAFMMNHARGLVCVAM
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEC
PGERLDALDIPLMVSRNTESLKTAFTVSVDYIPGTTTGISAADRAKTVRALVSEGSRPED
CCCCCCCCCCCEEEECCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
FARPGHIFPLRANPEGVLGRTGHTEAAVDLCRLAGKFPSGTICEVANDDGTMARLPQLEI
HCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCEE
FAERHGLLVVTIKDLVSYLKGEVVEEMVQKQVA
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194